- 1901. 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2,3-dihydro-2-imino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxomonosodium Salt,(6R-(6alpha,7beta(Z)))-
- [The sodium salt form of ceftizoxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Ceftizoxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis. ( NCI )] (UMLS (NCI) C0282391) =Organic Chemical; Antibiotic ;
=CEFTIZOXIME;
=ceftizoxime 1 gm injectable powder for injection;
ceftizoxime 10 gm injectable powder for injection;
CEFTIZOXIME SODIUM 2 GM/VIL;
CEFTIZOXIME SODIUM 20 MG/ML;
CEFTIZOXIME SODIUM 40 MG/ML;
CEFTIZOXIME SODIUM 1 GM;
CEFTIZOXIME SODIUM 2 GM;
CEFTIZOXIME SODIUM 500 MG | - 1951. 6 minutes post challenge
- (UMLS (HL7) C1547084) =Temporal Concept =Time delay post challenge;
|
- 1902. 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((1Z)-2-(4-methyl-5-thiazolyl)ethenyl)-8-oxo-,2,2-dimethyl-1-oxopropoxy)methyl Ester,(6R,7R)-
- [A semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Cefditoren pivoxil is a prodrug that is rapidly hydrolyzed by intestinal esterases during absorption to the microbiologically active cefditoren, an active aminothiazolyl cephalosporin. Cefditoren inactivates penicillin binding proteins (PBPs) thereby interfering with peptidoglycan synthesis and inhibiting bacterial cell wall synthesis. Another consequence of beta-lactam exposure results in the loss of lipoteichoic acids from the cell wall. Lipoteichoic acids inhibit murein hydrolase activity and their absence from the cell wall triggers uncontrolled autolytic activity rendering bacterial cells susceptible to osmotic shock. This results in a reduction of cell wall stability and causes cell lysis. ( NCI )] (UMLS (NCI) C0245519) =Organic Chemical; Antibiotic ;
=CEFDITOREN;
Unclassified Ingredients | - 1952. 6 phosphofructokinase
- [An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, C TYPE; found in platelets, brain, and other tissues. ( MSH )] (UMLS (CSP) C0031651) =Amino Acid, Peptide, or Protein; Enzyme ;
=alcohol phosphotransferase;
|
- 1903. 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl)carbonyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, Disodium Salt,(6R-(6alpha,7alpha))-
- [The disodium salt form of cefotetan and a semi-synthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefotetan disodium causes inhibition of bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. This results in a reduction of cell wall stability and causes cell lysis. ( NCI )] (UMLS (NCI) C0700471) =Organic Chemical; Antibiotic =CEFOTETAN;
=CEFOTETAN DISODIUM 1 GM/VIL;
CEFOTETAN DISODIUM 2 GM/VIL;
CEFOTETAN DISODIUM 1 GM/50ML;
CEFOTETAN DISODIUM 2 GM/50ML;
CEFOTETAN DISODIUM 10 GM/VIL;
CEFOTETAN DISODIUM 2 GM;
CEFOTETAN DISODIUM 1 GM;
| - 1953. 6 thiopurine riboside
- [ ] (UMLS (CSP) C0599534) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 1904. 5-[3, 3-Bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamide
- [A synthetic derivative of imidazole with potent antineoplastic properties. Imidazole mustard alkylates DNA, preferentially at guanine residues, resulting in DNA interstrand crosslinks and inhibition of DNA replication and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0063382) =Organic Chemical; Pharmacologic Substance
| - 1954. 6,7 benzomorphan
- [ ] (UMLS (CSP) C0178433) =Organic Chemical ;
=morphinan;
=cyclazocine;
PENTAZOCINE |
- 1905. 5-[5-fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide)
- (UMLS (NCI) C1176020) Sunitinib =Organic Chemical; Pharmacologic Substance
| - 1955. 6,7-Epoxytropine Tropate
- [A toluidine derivative and intermediate-acting amino amide with local anesthetic property. Prilocaine stabilizes the neuronal membrane by preferential binding to and inhibiting depolarization of the voltage-gated sodium channel. This results in a decrease in membrane permeability and subsequent inhibition of the ionic sodium influx required for the initiation and conduction of impulses. ( NCI )] (UMLS (NCI) C0033124) =Organic Chemical; Pharmacologic Substance =Anilides;
[CN204] LOCAL ANESTHETICS, INJECTION =2-(Propylamino)-o-propionotoluidide Hydrochloride;
PRILOCAINE 2.5 % |
- 1906. 5-[[2-(2-Butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole
- [A synthetic derivative of benzodioxole and used as an insecticide synergist, Piperonyl Butoxide enhances the active properties of pyrethrin, pyrethroid, rotenone, and carbamate pesticide ingredients by inhibiting insect microsomal enzyme detoxification activity. It is toxic and suspected of causing anorexia, carcinogenesis, convulsions, and dermal irritation, as well as hepatic and renal damage. (NCI04) ( NCI )] (UMLS (NCI) C0031962) =Organic Chemical; Hazardous or Poisonous Substance =Dioxoles;
Pediculicide =PIPERONYL BUTOXIDE TECHNICAL;
PIPERONYL BUTOXIDE 3 %;
| - 1956. 6-(2,2-Dimethyl-5-oxo-4-phenyl-1-imidazolidinyl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid
- [A semi-synthetic penicillin compound with bactericidal properties. Hetacillin is a prodrug that is converted to ampicillin. Ampicillin binds to inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs, including transpeptidases, carboxypeptidases, and endopeptidases, participate in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. This results in the weakening of the bacterial cell wall and eventually causes cell lysis. (NCI05) ( NCI )] (UMLS (NCI) C0062587) =Organic Chemical; Antibiotic ;
|
- 1907. 5-[[4-[4(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl\-2,4-thiazolidinedione
- [A drug used in diabetes treatment that is being studied for its effect on reducing the risk of cancer cell growth in fat tissue. ( NCI )] (UMLS (NCI) C0245514) =Organic Chemical; Pharmacologic Substance ;
=Chromans;
antihyperglycemic;
thiazole;
Unclassified Ingredient Preparations | - 1957. 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid
- [A topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression. This agent stimulates skin growth through modulation of cellular differentiation, inflammatory processes and keratinization of follicular epithelial cells. Adapalene may increase dermal sensitivity to ultraviolet radiation. (NCI04) ( NCI )] (UMLS (NCI) C0165631) =Organic Chemical; Pharmacologic Substance =naphthalene;
[DE752] ANTIACNE AGENTS, TOPICAL =ADAPALENE 0.1 % |
- 1908. 50-59% BDY BRN/10-19% 3D
- [ ] (UMLS (ICD9CM) C0161349) =Injury or Poisoning
| - 1958. 6-(methylmercapto)purine ribonucleoside
- [A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation. (NCI04) ( NCI )] (UMLS (NCI) C0025828) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
|
- 1909. 50-59% BDY BRN/20-29% 3D
- [ ] (UMLS (ICD9CM) C0161350) =Injury or Poisoning
| - 1959. 6-11 years old
- [a human child aged 6 through 11 years of age; when school grades are referenced, this age group is typically grade 1-5 or 6; also index with appropriate human and clinical research terms. ( CSP )] (UMLS (CSP) C0596947) =Age Group ;
=child (0-11);
|
- 1910. 50-59% BDY BRN/3 DEG NOS
- [ ] (UMLS (ICD9CM) C0161348) =Injury or Poisoning
| - 1960. 6-Acetamido-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4H)-one
- (UMLS (NCI) C0050460) =Organic Chemical; Pharmacologic Substance
|
- 1911. 50-59% BDY BRN/30-39% 3D
- [ ] (UMLS (ICD9CM) C0161351) =Injury or Poisoning
| - 1961. 6-Aminocaproic Acid
- [A synthetic lysine derivative with antifibrinolytic activity. Aminocaproic acid competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin (fibrinolysin), an enzyme that degrades fibrin clots as well as fibrinogen and other plasma proteins including the procoagulant factors V and VIII. Aminocaproic acid competitively reduces the conversion of plasminogen to plasmin by plasminogen activators. It directly inhibits proteolytic activity of plasmin, but higher doses are required than are needed to reduce plasmin formation. Aminocaproic acid is used in the treatment of hemorrhage and prophylactically against hemorrhage, including hyperfibrinolysis-induced hemorrhage and postsurgical hemorrhage. ( NCI )] (UMLS (NCI) C0000608) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 1912. 50-59% BDY BRN/40-49% 3D
- [ ] (UMLS (ICD9CM) C0161352) =Injury or Poisoning
| - 1962. 6-Chloro-2,3,4,5-tetrahydro-1-(p-hydroxyphenyl)-1H-3-benzazepine-7,8-diol methanesulfonate(salt)
- [The mesylate salt form of fenoldopam, a benzazepine derivative with rapid-acting vasodilator activity. Fenoldopam mesylate is a racemic mixture of S- and R- isomers; the latter is responsible for the biological activity and has a significantly higher affinity for dopamine D1-like receptors (D1 and D5) as well as moderate affinity to alpha2-adrenoceptors. This agent selectively activates the dopamine D1-like receptor, thereby causing vasodilatation and increasing renal perfusion. ( NCI )] (UMLS (NCI) C0700481) =Organic Chemical; Pharmacologic Substance =FENOLDOPAM;
=FENOLDOPAM MESYLATE 10 MG/ML;
|
- 1913. 50-59% BDY BRN/50-59% 3D
- [ ] (UMLS (ICD9CM) C0161353) =Injury or Poisoning
| - 1963. 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- [The hydrogenated derivative of chlorothiazide, a thiazide diuretic with antihypertensive and anti-urolithic effects. This agent binds to the electroneutral Na-K-Cl cotransporter (NKCC) and thereby impairs Na+, K+ and Cl- reabsorption on the luminal membrane of the early segment in the distal convoluted tubule in the kidney. This leads to an increase in urinary excretion of sodium, chloride, potassium, bicarbonate and water subsequently reducing plasma and extracellular fluid volume leading to a reduction in blood pressure. Hydrochlorothiazide also decreases urinary calcium and uric acid excretion by direct action on the distal tubule. ( NCI )] (UMLS (NCI) C0020261) =Organic Chemical; Pharmacologic Substance ;
=chlorothiazide;
[CV701] THIAZIDES/RELATED DIURETICS =2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-Dioxide;
Hydrochlorothiazide 10 MG/ML;
HYDROCHLOROTHIAZIDE 100 MG;
HYDROCHLOROTHIAZIDE 12.5 MG;
HYDROCHLOROTHIAZIDE 15 MG;
HYDROCHLOROTHIAZIDE 25 MG;
HYDROCHLOROTHIAZIDE 30 MG;
HYDROCHLOROTHIAZIDE 50 MG;
HYDROCHLOROTHIAZIDE 6.25 MG;
HYDROCHLOROTHIAZIDE 125 MG;
HYDROCHLOROTHIAZIDE .25 MG |
- 1914. 506U78
- [An anticancer drug that belongs to the family of drugs called antimetabolites. ( NCI )] (UMLS (NCI) C0759671) Compound 506U78;
GW506U78;
=Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 1964. 6-Chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine Dihydrochloride
- [The dihydrochloride salt of quinacrine, a 9-aminoacridine derivative, with potential antineoplastic property in addition to its antiparasitic activity. Quinacrine may exert its antineoplastic activity by inhibiting the transcription and activity of both basal and inducible nuclear factor-kappaB (NF-kappaB). Continuous NF-kappaB signaling, as present in many tumors as well as during chronic inflammation, promotes the expression of anti-apoptotic proteins and cytokines while suppressing the expression of pro-apoptotic proteins, such as p53, thereby inhibiting apoptosis and inducing proliferation. The repression of NF-kappaB by quinacrine leads to an induction of the transcription of the tumor suppressor p53. The activation of p53 restores p-53-dependent apoptotic pathways and potentially leads to an inhibition of tumor cell growth. ( NCI )] (UMLS (NCI) C0949411) Atabrine Dihydrochloride;
Mepacrine Dihydrochloride;
Quinacrine Dihydrochloride;
Quinacrine Hydrochloride;
SN 390 =Organic Chemical; Pharmacologic Substance |
- 1915. 51 chromium release assay
- [effector Cytotoxic T Lymphocytes (CTL) bind targets (infected cells) bearing virus peptide on syngeneic Class I MHC and signal the targets to undergo apoptosis; if the targets are labeled with 51Chromium before the CTL are added, the amount of 51Cr released into the supernatant is proportional to the number of targets killed. ( CSP )] (UMLS (CSP) C0201618) =Laboratory Procedure =immunologic assay;
| - 1965. 6-D-(2-naphthyl)alanyl-GnRH
- [A potent synthetic agonist of GONADOTROPIN-RELEASING HORMONE with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central PRECOCIOUS PUBERTY and ENDOMETRIOSIS. ( MSH )] (UMLS (NCI) C0064906) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=D-His-6-Pro-8-NEt-LHRH;
[HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER =(6-D-(2-Naphthyl)alanine)LHRH Acetate;
|
- 1916. 510 (K)
- (UMLS (HL7) C1548593) =Idea or Concept =Marketing basis;
| - 1966. 6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig)
- [GRH/LHRH analog used to suppress circulating gonadotropin and sex steroid levels; USP lists as an antineoplastic. ( CSP )] (UMLS (NCI) C0085272) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine; Hormone =[AN000] ANTINEOPLASTICS;
D-His-6-Pro-8-NEt-LHRH;
peptide hormone analog;
[AN500] ANTINEOPLASTIC HORMONES =6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) Monoacetate |
- 1917. 510 (K) exempt
- (UMLS (HL7) C1548592) =Idea or Concept =Marketing basis;
| - 1967. 6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) Monoacetate
- [The acetate salt of a synthetic nonapeptide analogue of gonadotropin-releasing hormone. Leuprolide binds to and activates gonadotropin-releasing hormone (GnRH) receptors. Continuous, prolonged administration of leuprolide in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. This agent reduces testosterone production to castration levels and may inhibit androgen receptor-positive tumor progression. ( NCI )] (UMLS (NCI) C0700596) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone =6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig);
=LEUPROLIDE ACETATE 11.25 MG;
LEUPROLIDE ACETATE 15 MG;
LEUPROLIDE ACETATE 22.5 MG;
LEUPROLIDE ACETATE 30 MG;
LEUPROLIDE ACETATE 65 MG;
LEUPROLIDE ACETATE 72 MG;
LEUPROLIDE ACETATE 7.5 MG;
LEUPROLIDE ACETATE 1 MG/0.2ML;
LEUPROLIDE ACETATE 3.75 MG |
- 1918. 51W89
- (UMLS (NCI) C0530101) =Organic Chemical; Pharmacologic Substance ;
| - 1968. 6-D-Tryptophan-, 4,4'Mmethylenebis(3-hydroxy-2-naphthalenecarboxylate) (Salt)
- [The pamoate salt of triptorelin, a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion after prolonged administration. After chronic, continuous administration, a sustained decrease in LH, FSH and testicular and ovarian steroidogenesis is observed. The serum testosterone concentration may fall to levels typically seen in surgically castrated men. (NCI04) ( NCI )] (UMLS (NCI) C1137102) Pamorelin;
Triptorelin Pamoate;
TRIPTORELIN PAMOATE UNIDENTIFIED;
TRIPTORELIN PAMOATE PREPARATION;
TRIPTORELIN PAMOATE UNIDENTIFIED =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone =6-D-Tryptophan-LH-RH;
Unclassified Ingredients =TRIPTORELIN PAMOATE 11.25 MG |
- 1919. 520C9x22 Bispecific Antibody
- [A partially humanized bivalent antibody targeting cytotoxic effector cells expressing Fc gamma receptor type I (Fc gammaRI, or CD64) against HER2/neu-overexpressing tumor cells. Bispecific antibody MDX-H210 was constructed by chemically linking Fab' fragments of the anti-HER2/neu-specific monoclonal antibody, 520C9, and the Fab' fragments of the anti-Fc gammaRI-specific monoclonal antibody, H22. While HER2/neu is overexpressed in a variety of malignancies, expression of Fc gammaRI is limited primarily to cytotoxic immune cells, including monocytes, macrophages, and cytokine-activated polymorphonuclear (PMN) cells. Therefore, HER2/neu expressing tumor cells bound by MDX-H210 can be selectively recognized by effector cells and triggers antibody-dependent cell-mediated cytotoxicity (ADCC), resulting in tumor cell lysis. ( NCI )] (UMLS (NCI) C0281736) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 1969. 6-D-Tryptophan-9-(N-ethyl-L-prolinamide)-1-9-luteinizing Hormone-releasing Factor (Swine)
- [A synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04) ( NCI )] (UMLS (NCI) C0083220) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
|
- 1920. 55 kDa Erythrocyte Membrane Protein
- [Expressed in a variety of tissues (abundantly in erythroid stem cells to differentiated reticulocytes) by human MPP1 Gene (MAGUK Family), 466-aa 52-kDa Palmitoylated Membrane Protein 1 contains 1 PDZ/DHR domain, 1 conserved SH3 domain, 1 guanylate kinase-like domain, and a region that binds to cytoskeletal protein 4.1. Tightly associated with the plasma membrane and extensively palmitoylated, MPP1 interacts with DLG5 and is suspected to play a role in signal transduction. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. (NCI) ( NCI )] (UMLS (NCI) C1335296) EMP55;
Erythrocyte Membrane Protein p55;
p55;
Palmitoylated Membrane Protein 1;
Palmitoylated Membrane Protein 1 55kD;
PEMP =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 1970. 6-D-Tryptophan-LH-RH
- [A hormonal anticancer drug that belongs to the family of drugs called gonadotropin-releasing analogues. ( NCI )] (UMLS (NCI) C0077275) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone =[AN500] ANTINEOPLASTIC HORMONES;
Unclassified Ingredients =6-D-Tryptophan-, 4,4'Mmethylenebis(3-hydroxy-2-naphthalenecarboxylate) (Salt) |
- 1921. 566C80
- (UMLS (NCI) C0700939) =Organic Chemical; Pharmacologic Substance ;
| - 1971. 6-deoxy-3,5 di-O-methyl 6-(3-methyl-3-nitrosoureido)-alpha-D-glucofuranoside
- (UMLS (NCI) C0116847) =Organic Chemical; Pharmacologic Substance ;
|
- 1922. 593A
- (UMLS (NCI) C0098709) =Organic Chemical; Pharmacologic Substance ;
| - 1972. 6-DIAZO-5-OXO-L-NORLEUCINE
- [An antibiotic isolated from Streptomyces with potential antineoplastic activity. Diazooxonorleucine inhibits several glutamine-dependent biosynthetic pathways including the synthesis of D-glucosamine phosphate, purines and pyrimidines. As an L-glutamine antagonist, diazooxonorleucine inhibits phosphate-activated glutaminase, thereby interfering with glutamine metabolism, ultimately depleting cells of this essential amino acid and reducing the capacity to proliferate. Another mechanism of action including inhibition of glycoprotein, gamma-guanosine triphosphatease, DNA and RNA synthesis has been proposed. ( NCI )] (UMLS (NCI) C0012020) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 1923. 5a
- [Maxillary right first premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553637) =Medical Device =Artificial dentition;
| - 1973. 6-Dibromodideoxydulcitol
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0026252) =Carbohydrate; Pharmacologic Substance ;
|
- 1924. 5a-Reductase Inhibition
- (UMLS (NCI) C0280703) =Therapeutic or Preventive Procedure
| - 1974. 6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline
- [Antioxidant; also a post-harvest dip to prevent scald on apples and pears. ( MSH )] (UMLS (NCI) C0015051) =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid
|
- 1925. 5alpha,7alpha(S))-alpha-tert-Butyl-17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol Hydrochloride
- [The hydrochloride salt form of buprenorphine, a synthetic phenanthrene with narcotic analgesic activity. Buprenorphine hydrochloride is a partial agonist at the mu-opioid receptor and an antagonist at the kapa-opioid receptor in the central nervous system. However, under the conditions of recommended use it behaves as a classic mu-opioid agonist, mimicking the actions of endogenous peptides at CNS opioid receptors. The agonist action results in a raised pain threshold and increased tolerance to pain. However, it also causes sedation, physical dependence, and respiratory depressant effects and decreases heart rate and blood pressure. ( NCI )] (UMLS (NCI) C0701445) =Organic Chemical; Pharmacologic Substance ;
=buprenorphine;
=BUPRENORPHINE HYDROCHLORIDE 0.3 MG/ML;
BUPRENORPHINE HYDROCHLORIDE 2 MG;
BUPRENORPHINE HYDROCHLORIDE 8 MG | - 1975. 6-Fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic Acid
- [A synthetic quinolinecarboxylic acid analogue with antineoplastic properties. Brequinar inhibits the enzyme dihydroorotate dehydrogenase, thereby blocking de novo pyrimidine biosynthesis. This agent may also enhance the in vivo antitumor effect of antineoplastic agents such as 5-FU. (NCI04) ( NCI )] (UMLS (NCI) C0280509) =Organic Chemical; Pharmacologic Substance
|
- 1926. 5alphaR
- [ ] (UMLS (CSP) C0599937) =Amino Acid, Peptide, or Protein; Enzyme
| - 1976. 6-Hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone Hydrochloride
- [The hydrochloride salt form of raloxifene, a selective benzothiophene estrogen receptor modulator (SERM) with lipid lowering effects and activity against osteoporosis. Raloxifene hydrochloride specifically binds to estrogen receptors in responsive tissue, including liver, bone, breast, and endometrium. The resulting ligand-receptor complex is translocated to the nucleus where, depending on the tissue type, it promotes or suppresses the transcription of estrogen-regulated genes, thereby exerting its agonistic or antagonistic effects. This agent functions as an estrogen agonist in lipid metabolism, thereby decreasing total and LDL cholesterol levels. In tissue like bone, it decreases bone resorption and bone turnover and increases bone mineral density. Raloxifene hydrochloride acts as an estrogen antagonist in uterine and breast tissue. This agent also exerts an anti-proliferative effect on estrogen-sensitive breast cancer. ( NCI )] (UMLS (NCI) C0618111) =Organic Chemical; Pharmacologic Substance ;
=[6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone;
=RALOXIFENE HYDROCHLORIDE 60 MG |
- 1927. 5FU/Leucovorin
- (UMLS (NCI) C0278707) =Therapeutic or Preventive Procedure
| - 1977. 6-Mercaptopurine Monohydrate
- (UMLS (NCI) C0886849) Purine-6-thiol Monohydrate;
Purine-6-thiol, monohydrate =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
|
- 1928. 5FU/Leucovorin/Gemcitabine
- (UMLS (NCI) C0677790) =Therapeutic or Preventive Procedure
| - 1978. 6-Mercaptopurine ribonucleoside
- [A sulfhydryl analog of inosine and an antimetabolite with potential antineoplastic and immunosuppressive properties. Thioinosine interferes with de novo purine synthesis and perturbs the pool of nucleotides necessary for DNA replication. As a result, this agent inhibits DNA synthesis, blocks cellular proliferation and induces apoptosis. ( NCI )] (UMLS (NCI) C0039904) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 1929. 5FU/Leucovorin/Irinotecan
- (UMLS (NCI) C0281534) =Therapeutic or Preventive Procedure
| - 1979. 6-Methoxy-7,4'-dihydroxyisoflavone
- (UMLS (NCI) C0253391) =Organic Chemical ;
|
- 1930. 5FU/Leucovorin/Levamisole
- (UMLS (NCI) C0278901) =Therapeutic or Preventive Procedure
| - 1980. 6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid
- [6-methoxy-alpha-methyl-2-naphthaleneacetic acid; nonsteroidal antiinflammatory drug (NSAID); acts by inhibiting cyclooxygenase and thus prostaglandin synthesis; tocolytic oxytocin antagonist. ( CSP )] (UMLS (NCI) C0027396) =Organic Chemical; Pharmacologic Substance =NSAIDs;
[CN850] ANTIPYRETICS;
Naphthaleneacetic Acids;
naphthalene;
antiarthritic agent;
oxidoreductase inhibitor;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;
[CN104] NONSTEROIDAL ANTI-INFLAMMATORY ANALGESICS =NAPROXEN SODIUM;
NAPROXEN 250 MG;
NAPROXEN 375 MG;
NAPROXEN 500 MG;
NAPROXEN 125 MG/5ML;
|
- 1931. 5H-(1)Benzopyrano(2,3-b)pyridine-3-carboxylic Acid, 2-Amino-7-(1-methylethyl)-5-oxo-
- [An anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor. Amlexanox decreases the time ulcers take to heal as well as the pain associated with the ulcers. ( NCI )] (UMLS (NCI) C0103049) =Organic Chemical; Pharmacologic Substance =aminopyridine;
[OR900] DENTAL AND ORAL AGENTS, TOPICAL OTHER =AMLEXANOX 5 %;
| - 1981. 6-Methyleneandrosta-1,4-diene-3,17-dione
- [An anticancer drug used to decrease estrogen production and suppress the growth of estrogen-dependent tumors. ( NCI )] (UMLS (NCI) C0851344) Exemestane;
EXEMESTANE PREPARATION =Steroid; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
FCE 24304 =EXEMESTANE 25 MG |
- 1932. 5H-Benzo(5,6)cyclohepta(1,2-b)pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-
- [A long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms. ( NCI )] (UMLS (NCI) C0908935) Desloratadine;
DESLORATADINE PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=[AH900] ANTIHISTAMINES, OTHER;
Unclassified Ingredients =DESLORATADINE 5 MG;
| - 1982. 6-N-(1-hydroxymethyla-2-hydroxy)ethylamino-12,13-dihydro-13-(beta-D-gluco pyranosyl)-5H-indolo[2,3-a]-pyrrolol[3,4-c]-carbazole-5,7(6H)-dione
- [A synthetic indolocarbazole with antineoplastic activity. Edotecarin inhibits the enzyme topoisomerase I through stabilization of the DNA-enzyme complex and enhanced single-strand DNA cleavage, resulting in inhibition of DNA replication and decreased tumor cell proliferation. (NCI04) ( NCI )] (UMLS (NCI) C1328673) Edotecarin;
=Organic Chemical; Pharmacologic Substance |
- 1933. 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)-2-methylpropyl)-, Maleate(1:1)
- [The maleate salt form of trimipramine, a tricyclic secondary amine of the dibenzazepine class, with an antidepressant property. Trimipramine maleate appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. ( NCI )] (UMLS (NCI) C0242523) =Organic Chemical; Pharmacologic Substance =TRIMIPRAMINE;
=TRIMIPRAMINE MALEATE 100 MG;
TRIMIPRAMINE MALEATE 25 MG;
TRIMIPRAMINE MALEATE 50 MG | - 1983. 6-NC
- [A synthetic solid appearing as chrome-red crystals or orange-yellow to light-yellow needles that is slightly soluble in acetic acid, cold ethanol, diethyl ether, benzene, and carbon disulfide, and soluble in hot nitrobenzene. It is not used for any commercial applications and is used only for research purposes, principally as an internal standard in the chemical analysis of nitroarenes. The primary route of potential human exposure to 6-nitrochrysene is inhalation. Low concentrations of this chemical have been found in ambient airborne particulates. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0049682) =Organic Chemical; Hazardous or Poisonous Substance
|
- 1934. 5H-Dibenz(b,f)azepine-5-carboxamide
- [anticonvulsant and antineuralgic used in the treatment of pain associated with trigeminal neuralgia and in epilepsy manifested by tonic-clonic and partial seizures. ( CSP )] (UMLS (NCI) C0006949) =Organic Chemical; Pharmacologic Substance =[CN100] ANALGESICS;
[CN400] ANTICONVULSANTS;
azepine;
Dibenzazepines =10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide;
CARBAMAZEPINE 100 MG;
CARBAMAZEPINE 100 MG/5ML;
CARBAMAZEPINE 200 MG;
CARBAMAZEPINE 300 MG;
CARBAMAZEPINE 400 MG;
| - 1984. 6-O-Methylerythromycin
- [semi-synthetic macrolide antibiotic; derivative of erythromycin. ( CSP )] (UMLS (NCI) C0055856) =Organic Chemical; Antibiotic ;
=macrolide antibiotic;
ERYTHROMYCIN;
[AM200] ERYTHROMYCINS/MACROLIDES;
[GA303] H.PYLORI AGENTS =CLARITHROMYCIN 125 MG/5ML;
CLARITHROMYCIN 250 MG;
CLARITHROMYCIN 500 MG;
CLARITHROMYCIN 250 MG/5ML;
CLARITHROMYCIN 187.5 MG/5ML;
CLARITHROMYCIN 28 X 500 MG;
|
- 1935. 5H-Dibenzo(a,d)cycloheptene-5-propanamine, N-methyl-, Hydrochloride
- [The hydrochloride salt form of protriptyline, a tricyclic secondary amine with antidepressant property. Protriptyline hydrochloride blocks the re-uptake of norepinephrine and serotonin by nerve terminals, thereby increasing available norepinephrine and serotonin. Protriptyline does not block dopamine transport but may have an indirect dopamine-facilitating effect through interactions of increased peri-synaptic abundance of norepinephrine, particularly in the cerebral cortex, where adrenergic terminals exceed dopaminergic terminals. This results in elevation of mood and behavioral activity. In addition, this agent exhibits anticholinergic activity. ( NCI )] (UMLS (NCI) C0700557) =Organic Chemical; Pharmacologic Substance ;
=PROTRIPTYLINE;
=PROTRIPTYLINE HYDROCHLORIDE 10 MG;
PROTRIPTYLINE HYDROCHLORIDE 5 MG;
| - 1985. 6-Propyl-2-thiouracil
- [A thiourea derivative with antithyroid property. Propylthiouracil (PTU) interferes with the oxidation of iodine possibly by interaction with peroxidase or a peroxidase-mediated complex reaction, thereby inhibiting synthesis of thyroid hormones tri-iodothyronine (T3) and thyroxine (T4). In addition, this agent inhibits the Type I 5'-deiodinase (D1), an enzyme involved in the peripheral conversion of thyroxine to tri-iodothyronine. This results in decreased plasma triodothyronine concentrations and decreased entrance of thyroxine into cells thereby reducing thyroid hormone activity. ( NCI )] (UMLS (NCI) C0033511) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =thiouracil;
[HS852] ANTITHYROID AGENTS =PROPYLTHIOURACIL 50 MG;
|
- 1936. 5H-indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione,1,11-dichloro-12,13-dihydro-12-(4-O-methyl-beta-D-glucopyranosyl)
- [An anticancer drug that belongs to the family of drugs called antineoplastic antibiotics. ( NCI )] (UMLS (NCI) C0073012) =Organic Chemical; Antibiotic ;
| - 1986. 6-Quinoxalinamine, 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1)
- [The tartrate salt form of brimonidine, an imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine tartrate acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine tartrate also enhances the outflow of aqueous humor. This drug is used in the treatment of glaucoma to reduce intraocular pressure. ( NCI )] (UMLS (NCI) C0077768) =Organic Chemical; Pharmacologic Substance ;
=Brimodine;
=BRIMONIDINE TARTRATE 0.2 %;
BRIMONIDINE TARTRATE 0.15 %;
|
- 1937. 5HT transporter
- [responsible for accumulation of serotonin in peripheral blood cells, placenta, and lungs. ( CSP )] (UMLS (CSP) C0170657) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=membrane transport protein;
| - 1987. 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine
- [immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis; possible carcinogen. ( CSP )] (UMLS (NCI) C0004482) =Organic Chemical; Pharmacologic Substance
|
- 1938. 5i
- [Maxillary right first premolar implant ( HL7V3.0 )] (UMLS (HL7) C1552169) =Medical Device =Artificial dentition;
| - 1988. 6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic Acid]cyclosporin D
- [An analogue of cyclosporin-A. Valspodar inhibits p-glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention and activity of some drugs in some drug-resistant tumor cells. This agent also induces caspase-mediated apoptosis. (NCI04) ( NCI )] (UMLS (NCI) C0753474) Cyclo((2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoyl)-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-me;
SZD PSC 833;
Valspodar;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
|
- 1939. 5p
- [Maxillary right first premolar prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553550) =Body Part, Organ, or Organ Component =Artificial dentition;
| - 1989. 6-[(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]- 3-Pyridinecarboxylic Acid, Ethyl Ester
- [A synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation. (NCI04) ( NCI )] (UMLS (NCI) C0288792) =Organic Chemical; Pharmacologic Substance ;
=Nicotinic Acids;
[DE752] ANTIACNE AGENTS, TOPICAL =TAZAROTENE 0.1 %;
TAZAROTENE 0.05 % |
- 1940. 5p Deletion Syndrome
- [infantile syndrome characterized by a cat-like cry, failure to thrive, microcephaly, mental retardation, spastic quadriparesis, micro- and retrognathia, glossoptosis, bilateral epicanthus, hypertelorism, and tiny external genitalia; caused by a deletion of the short arm of chromosome 5. ( CSP )] (UMLS (NCI) C0010314) =Congenital Abnormality; Disease or Syndrome =Abnormalities, Multiple;
Chromosomal anomalies;
syndrome;
Chromosomal Disorders, Nervous System | - 1990. 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
- [A quinolinone derivative and cellular phosphodiesterase inhibitor, more specific for phosphodiesterase III (PDE III). Although the exact mechanism of action of is unknown, cilostazol and its metabolites appears to inhibit PDE III activity, thereby suppressing cyclic adenosine monophosphate (cAMP) degradation. This results in an increase in cAMP in platelets and blood vessels, leading to inhibition of platelet aggregation and vasodilation. ( NCI )] (UMLS (NCI) C0055729) =Organic Chemical; Pharmacologic Substance ;
=Tetrazoles;
[CV900] CARDIOVASCULAR AGENTS, OTHER =CILOSTAZOL 100 MG;
CILOSTAZOL 50 MG;
|
- 1941. 5pd
- [Maxillary right first premolar distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553549) =Medical Device =Artificial dentition;
| - 1991. 6-[O-(1,1-Dimethylethyl)-D-serine]-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) 2-(aminocarbonyl)hydrazide
- [A drug that belongs to the family of drugs called gonadotropin-releasing hormone analogues. Goserelin is used to block hormone production in the ovaries or testicles. ( NCI )] (UMLS (NCI) C0120107) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=D-His-6-Pro-8-NEt-LHRH;
[AN500] ANTINEOPLASTIC HORMONES =D-Ser(bu(t))(6)azgly(10)-LHRH Acetate;
|
- 1942. 5pm
- [Maxillary right first premolar mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553551) =Medical Device =Artificial dentition;
| - 1992. 6-[O-(1,1-Dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig)
- [An anticancer drug that belongs to the family of drugs called gonadotropin-releasing hormones. In prostate cancer therapy, buserelin blocks the production of testosterone in the testicles. ( NCI )] (UMLS (NCI) C0006456) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
|
- 1943. 5q
- [Distal (long) arm of chromosome 5 ( NCI )] (UMLS (NCI) C0796347) Chromosome 5 Distal Arm;
Chromosome 5 Long Arm;
Chromosome 5q;
=Nucleotide Sequence | - 1993. 60-69% BDY BRN/10-19% 3D
- [ ] (UMLS (ICD9CM) C0161356) =Injury or Poisoning
|
- 1944. 5q- Syndrome
- [5Q minus syndrome. A rare disorder caused by loss of part of the long arm (Q arm) of human chromosome 5. This syndrome affects myeloid (bone marrow) cells, causing treatment-resistant anemia, and myelodysplastic syndromes that may lead to acute myelogenous leukemia. ( NCI )] (UMLS (NCI) C0740302) Myelodysplastic Syndrome Associated with Isolated del (5q) Chromosome Abnormality =Disease or Syndrome ;
| - 1994. 60-69% BDY BRN/20-29% 3D
- [ ] (UMLS (ICD9CM) C0161357) =Injury or Poisoning
|
- 1945. 5q31
- [A chromosome band present on 5q ( NCI )] (UMLS (NCI) C0796362) Chromosome 5q31 =Nucleotide Sequence
| - 1995. 60-69% BDY BRN/3 DEG NOS
- [ ] (UMLS (ICD9CM) C0161355) =Injury or Poisoning
|
- 1946. 5s
- [Supernumerary maxillary right first premolar ( HL7V3.0 )] (UMLS (HL7) C1552119) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
| - 1996. 60-69% BDY BRN/30-39% 3D
- [ ] (UMLS (ICD9CM) C0161358) =Injury or Poisoning
|
- 1947. 6
- [Maxillary right canine ( HL7V3.0 )] (UMLS (HL7) C0227039) tooth 6 =Body Part, Organ, or Organ Component =Permanent dentition;
| - 1997. 60-69% BDY BRN/40-49% 3D
- [ ] (UMLS (ICD9CM) C0161359) =Injury or Poisoning
|
- 1948. 6 aminonicotinamide
- [A synthetic analogue and nicotinamide antagonist with cytotoxic properties, 6-Aminonicotinamide forms an abnormal NAD (ubiquitous metabolic pathway coenzyme) analog that inhibits NAD-dependent enzyme activity associated with ATP production. 6-Aminonicotinamide impairs cartilage formation, may have teratogenic effects, and enhances the effect of radiation and cisplatin treatment (formation of platinum-DNA complexes). (NCI04) ( NCI )] (UMLS (CSP) C0000610) =Organic Chemical; Pharmacologic Substance; Vitamin; Hazardous or Poisonous Substance
| - 1998. 60-69% BDY BRN/50-59% 3D
- [ ] (UMLS (ICD9CM) C0161360) =Injury or Poisoning
|
- 1949. 6 hours
- (UMLS (HL7) C1292428) =Temporal Concept ;
=Duration categories;
| - 1999. 60-69% BDY BRN/60-69% 3D
- [ ] (UMLS (ICD9CM) C0161361) =Injury or Poisoning
|
- 1950. 6 hours post challenge
- (UMLS (HL7) C1547083) =Temporal Concept =Time delay post challenge;
| - 2000. 60S Ribosomal pProtein L19
- [Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. Ribosomal Protein L19, encoded by the RPL19 gene is a ribosomal protein that is a component of the 60S subunit. This protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. (From LocusLink) ( NCI )] (UMLS (NCI) C0073283) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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