- 2101. 87U6
- [Encoded by human GNAI3 Gene (G-Alpha 1 Family), 353-aa 40-kDa G(i) Alpha 3 Protein is a guanine nucleotide-binding alpha protein subunit of heterotrimeric G protein transducers (alpha, beta, gamma) in transmembrane signaling systems involved in hormonal regulation of adenylate cyclase. Containing virtually identical/similar beta and gamma chains, G proteins are most distinguished by alpha chains. G(i) proteins (alpha(i) subunit) inhibit cyclase in response to beta-adrenergic stimuli. Specific alpha chain regions appear to interact with guanine nucleotides, receptors, effector enzymes, and G protein beta-gamma complex. G proteins that inhibit adenylate kinase are substrates for pertussis toxin. GNAI3 is the stimulatory G protein of receptor-regulated K(+) channels. (NCI) ( NCI )] (UMLS (NCI) C1454213) G Protein Alpha Inhibiting Activity Polypeptide 3;
G(i) Alpha 3 Protein;
G(i) Alpha-3;
GNAI3;
Guanine Nucleotide Binding Protein Alpha Inhibiting Activity Polypeptide 3;
Guanine Nucleotide-Binding Protein G(k) Alpha Subunit =Amino Acid, Peptide, or Protein; Enzyme ;
| - 2151. 90% + BDY BRN/90% + 3RD
- [ ] (UMLS (ICD9CM) C0161391) =Injury or Poisoning
|
- 2102. 8a
- [Maxillary right central incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553640) =Medical Device =Artificial dentition;
| - 2152. 95 kDa Melanocyte-Specific Secreted Glycoprotein
- [Expressed in melanocytes and melanomas by human SILV Gene (PMEL17/NMB Family), 661-aa 70-kDa (precursor) Melanocyte Lineage-Specific Antigen gp100is a probable type I membrane protein containing a putative leader sequence, a potential membrane anchor segment, 5 potential N-glycosylation sites, high levels of serine and threonine, a PKD domain, and amino acid similarity to tyrosinase and CAS2 protein. PMEL17 cross reacts with antityrosinase antibodies and expression correlates with melanin content. The soluble ME20-S form is a probable proteolytic cleavage product. CD8 T lymphocytes recognize a noncontiguous spliced nonameric sequence of gp100 on melanoma cells. Splicing appears to occur by transpeptidation involving an acyl-enzyme intermediate. (NCI) ( NCI )] (UMLS (NCI) C0257766) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 2103. 8B-[(Methylthio)methyl]-6-propylergoline Monomethanesulfonate
- [A semi-synthetic ergot derivative and a dopamine agonist with antiparkinson property. Pergolide mesylate binds to and activates dopamine receptor subtypes D1 and D2, resulting in prolactin secretion inhibition, transient increase in serum concentration of growth hormone, and decrease in serum concentration of luteinizing hormone. Direct stimulation of postsynaptic dopamine receptors in the nigrostriatal system, may account for this agent's antiparkinson activity. ( NCI )] (UMLS (NCI) C0031008) =Organic Chemical; Pharmacologic Substance =PERGOLIDE;
=PERGOLIDE MESYLATE 0.05 MG;
PERGOLIDE MESYLATE 0.25 MG;
PERGOLIDE MESYLATE 1 MG | - 2153. 98 kD Nucleoporin
- [Encoded by human NUP98 Gene (GLFG Nucleoporin Family), 937-amino acid Nucleoporin 98 kD (NUP98) is up regulated by interferon and generated through proteolytic cleavage of a 186 kD precursor yielding NUP98 and NUP96, both associated with the nuclear pore complex (NPC). NPC targeting of NUP96 and NUP98 is cleavage dependent, which may regulate assembly of the NPC, comprised of nearly fifty nucleoporins involved in signal-mediated nuclear import and export of protein and RNA. NUP98 likely functions as an import docking protein. The NUP98 C-terminal RNA-binding domain also contains NPC target sequences, a novel protein fold, and an autocatalytic protease. NUP98 docking/transport function is localized to N-terminal GLFG/FXFG repeats. mRNA nuclear export inhibition by Vesicular Stomatitis Virus M Protein targets NUP98. (from Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0297065) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 2104. 8i
- [Maxillary right central incisor implant ( HL7V3.0 )] (UMLS (HL7) C1552172) =Medical Device =Artificial dentition;
| - 2154. 9a
- [Maxillary left central incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553641) =Body Part, Organ, or Organ Component =Artificial dentition;
|
- 2105. 8p
- [Maxillary right central incisor prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553559) =Body Part, Organ, or Organ Component =Artificial dentition;
| - 2155. 9AC colloidal dispersion
- [A colloidal dispersion formulation of 9-Aminocamptothecin, a water-insoluble camptothecin derivative. Aminocamptothecin binds to the nuclear enzyme topoisomerase I, thereby inhibiting repair of single-strand DNA breakages. Because the terminal lactone ring of aminocamptothecin required for the agent's antitumor activity spontaneously opens under physiological conditions to an inactive carboxy form, the drug must be administered over an extended period of time to achieve effective cytotoxicity. ( NCI )] (UMLS (NCI) C0677807) =Organic Chemical; Pharmacologic Substance ;
|
- 2106. 8p
- [Proximal (short) arm of chromosome 8 ( NCI )] (UMLS (NCI) C0796348) Chromosome 8 Proximal Arm;
Chromosome 8 Short Arm;
Chromosome 8p =Nucleotide Sequence | - 2156. 9H-Purine-9-acetaldehyde, .alpha.-(1-formyl-2-hydroxyethoxy)-1,6-dihydro-6-oxo-, (R-(R*, R*))- (9CI)
- [A toxic purine analogue. Inosine dialdehyde inhibits ribonucleotide reductase, resulting in decreased synthesis of DNA, RNA, and proteins, and G2/M-phase cell cycle arrest. This agent also forms stable covalent crosslinks in proteins, thereby inhibiting the activity of enzymes involved in nucleic acid synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0063555) =Organic Chemical; Pharmacologic Substance ;
|
- 2107. 8p22
- [A chromosome band present on 8p ( NCI )] (UMLS (NCI) C0796365) Chromosome 8p22 =Nucleotide Sequence
| - 2157. 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-
- [A thioxanthene derivative and a dopamine antagonist with antipsychotic property. Thiothixene blocks postsynaptic dopamine receptors in the mesolimbic system and medullary chemoreceptor trigger zone, thereby decreasing dopamine activity leading to decreased stimulation of the vomiting center and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks the D2 somatodendritic autoreceptor, thereby increasing dopamine turnover. Thiothixene possesses weak affinity for the histamine H1 and alpha-adrenergic receptors. ( NCI )] (UMLS (NCI) C0039955) =Organic Chemical; Pharmacologic Substance =Thioxanthenes;
[CN701] PHENOTHIAZINES/RELATED, ANTIPSYCHOTICS =9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-, Dihydrochloride, Dihydrate |
- 2108. 8pd
- [Maxillary right central incisor distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553558) =Medical Device =Artificial dentition;
| - 2158. 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-, Dihydrochloride, Dihydrate
- [The hydrochloride salt form of thiothixene, a thioxanthene derivative and a dopamine antagonist with antipsychotic property. Thiothixene blocks postsynaptic dopamine receptors in the mesolimbic system and medullary chemoreceptor trigger zone, thereby decreasing dopamine activity leading to decreased stimulation of the vomiting center and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks the D2 somatodendritic autoreceptor, thereby increasing dopamine turnover. Thiothixene possesses weak affinity for the histamine H1 and alpha-adrenergic receptors. ( NCI )] (UMLS (NCI) C0304386) =Organic Chemical; Pharmacologic Substance =9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-;
=THIOTHIXENE HYDROCHLORIDE 1 MG;
THIOTHIXENE HYDROCHLORIDE 5 MG;
THIOTHIXENE HYDROCHLORIDE 10 MG;
THIOTHIXENE HYDROCHLORIDE 20 MG;
THIOTHIXENE HYDROCHLORIDE 5 MG/ML;
THIOTHIXENE HYDROCHLORIDE 2 MG/ML;
THIOTHIXENE HYDROCHLORIDE 2 MG |
- 2109. 8pm
- [Maxillary right central incisor mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553560) =Medical Device =Artificial dentition;
| - 2159. 9i
- [Maxillary left central incisor implant ( HL7V3.0 )] (UMLS (HL7) C1552173) =Medical Device =Artificial dentition;
|
- 2110. 8s
- [Supernumerary maxillary right central incisor ( HL7V3.0 )] (UMLS (HL7) C1552122) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
| - 2160. 9p
- [Maxillary left central incisor prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553562) =Body Part, Organ, or Organ Component =Artificial dentition;
|
- 2111. 9
- [Maxillary left central incisor ( HL7V3.0 )] (UMLS (HL7) C0227043) tooth 9 =Body Part, Organ, or Organ Component =Permanent dentition;
| - 2161. 9pd
- [Maxillary left central incisor distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553563) =Medical Device =Artificial dentition;
|
- 2112. 9 minutes post challenge
- (UMLS (HL7) C1547091) =Temporal Concept =Time delay post challenge;
| - 2162. 9pm
- [Maxillary left central incisor mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553561) =Medical Device =Artificial dentition;
|
- 2113. 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,2
- [novel immunosuppressive drug used in transplantation; may inhibit receptor mediated activation of mast cells. ( CSP )] (UMLS (NCI) C0072980) =Organic Chemical; Antibiotic =macrolide antibiotic;
[IM600] IMMUNE SUPPRESSANTS =SIROLIMUS 1 MG/ML;
SIROLIMUS 1 MG;
SIROLIMUS 2 MG | - 2163. 9s
- [Supernumerary maxillary left central incisor ( HL7V3.0 )] (UMLS (HL7) C1552123) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 2114. 9,10,Anthracenedicarboxaldehyde
- [An anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but unlike doxorubicin, does not exhibit cardiotoxicity. (NCI04) ( NCI )] (UMLS (NCI) C0053776) =Organic Chemical; Pharmacologic Substance ;
| - 2164. 9S-6'-Methoxy-cinchonan-9-ol, Mono-D-gluconate(salt)
- [The gluconate salt form of quinidine, an alkaloid with antimalarial and antiarrhythmic (Class la) properties. Quinidine gluconate exerts its anti-malarial activity by acting primarily as an intra-erythrocytic schizonticide through association with the hemepolymer (hemozoin) in the acidic food vacuole of the parasite thereby preventing further polymerization by heme polymerase enzyme. This results in accumulation of toxic heme and death of the parasite. Quinidine gluconate exerts its antiarrhythmic effects by depressing the flow of sodium ions into cells during phase 0 of the cardiac action potential, thereby slowing the impulse conduction through the atrioventricular (AV) node, reducing the maximal rate of phase 0 depolarization and prolonging the refractory period. Quinidine gluconate also reduces the slope of phase 4 depolarization in Purkinje-fibres resulting in slowed conduction and reduced automaticity in the heart. ( NCI )] (UMLS (NCI) C0072869) =Organic Chemical; Pharmacologic Substance =QUINIDINE;
=(9S)-6'-Methoxycinchonan-9-ol Sulfate (2:1) (salt);
QUINIDINE GLUCONATE 80 MG/ML;
QUINIDINE GLUCONATE 324 MG |
- 2115. 9,10-Anthracenedione
- [A polycyclic aromatic hydrocarbon derived from anthracene or pthalic anhydride. Anthraquinone is used in the manufacture of dyes, in the textile and pulp industries, and as a bird repellant. ( NCI )] (UMLS (NCI) C0050133) =Organic Chemical; Antibiotic
| - 2165. A
- [Maxillary right second primary molar ( HL7V3.0 )] (UMLS (HL7) C0227089) =Body Part, Organ, or Organ Component =Primary dentition;
|
- 2116. 9,10-Dihydroergotamine Mesylate
- [An ergot derivative with agonistic activity for alpha-adrenergic, serotonergic, and dopaminergic receptors. Dihydroergotamine mesylate most likely relieves migraine headaches by binding to and stimulating the 5-HT1D receptor subtype, thereby causing constriction of cerebral blood vessels. However, it has also been proposed that dihydroergotamine mesylate acts upon 5-HT1D receptors on sensory nerve endings of the trigeminal system, thereby decreasing the release of pro-inflammatory neuropeptide release. ( NCI )] (UMLS (NCI) C0700532) =Organic Chemical; Pharmacologic Substance =DIHYDROERGOTAMINE;
=DIHYDROERGOTAMINE MESYLATE 1 MG/ML;
DIHYDROERGOTAMINE MESYLATE 4 MG/ML;
| - 2166. a
- [The period of time that it takes for Earth to make a complete revolution around the sun, approximately 365 days; a specific one year period. (NCI) ( NCI )] (UMLS (NCI) C0439234) =Temporal Concept =CalendarCycleTwoLetter;
CalendarCycleOneLetter;
UnitOfMeasureAtomInsens;
UnitOfMeasureAtomSens |
- 2117. 9,11-Conjugated Linoleic Acid
- [A slightly altered form of linoleic acid, which is an omega-6 fatty acid important to human health. It is found in beef and dairy fats. ( NCI )] (UMLS (NCI) C0050156) =Lipid ;
| - 2167. A
- [One of the seven base units of the International System of Units (Systeme International d'Unites, SI), the unit of electric current, named after the French physicist Andre Ampere. It is that constant current which, if maintained in two straight parallel conductors of infinite length and zero diameter separated by one meter in a vacuum, would produce between these conductors a force equal to 2x10(e)7 newton per meter of length. This is dependent upon the definitions of the meter, kilogram, and second. One ampere represents 6.24 x 10(e+18) unit electric charge carriers, such as electrons, passing a specified fixed point in one second. ( NCI )] (UMLS (NCI) C0457243) =Quantitative Concept =UnitOfMeasureAtomInsens;
|
- 2118. 9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester
- [A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerone is used in the treatment of hypertension and congestive heart failure. ( NCI )] (UMLS (NCI) C0961485) Eplerenone;
EPLERENONE PREPARATION;
=Steroid; Pharmacologic Substance =[CV704] POTASSIUM-SPARING/COMBINATIONS DIURETICS;
Unclassified Ingredients =EPLERENONE 25 MG;
EPLERENONE 50 MG;
EPLERENONE 100 MG;
| - 2168. A 2371
- [ ] (UMLS (CSP) C0702003) =Carbohydrate; Indicator, Reagent, or Diagnostic Aid; Antibiotic
|
- 2119. 9,13b-Dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepin-3-amine Hydrochloride
- [An histamine H1 receptor antagonist without sedative activity. Epinastine hydrochloride blocks the histamine H1 receptor and inhibits the release of histamine from mast cells. This prevents the typical allergic symptoms that are caused by histamine activity on capillaries, skin, mucous membranes, and on gastrointestinal and bronchial smooth muscles. Typical histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Epinastine also has affinity for the histamine H2, 5-HT2, and the alpha-1, alpha-2 adrenergic receptors. ( NCI )] (UMLS (NCI) C0772294) Alesion;
Epinastine Hydrochloride;
=Organic Chemical; Pharmacologic Substance ;
| - 2169. A and D Ointment
- [A topical preparation containing fat-soluble vitamins A and D usually in a lanolin-petrolatum base, A and D Ointment promotes healing of minor burns, rashes, sunburn, skin irritations, and acne; and prevents diaper rash. Vitamin A is essential for diverse cellular functions, immune system functions, and maintenance of mucous membranes, while vitamin D regulates calcium and phosphorous metabolism. (NCI04) ( NCI )] (UMLS (NCI) C0305093) =Clinical Drug =[VT050] VITAMIN A;
[VT500] VITAMIN D |
- 2120. 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine, Fumarate
- [A pro-drug, a fumaric acid salt of tenofovir and an acyclic nucleoside phosphonate diester analog with antiviral property. In vivo tenofovir disoproxil fumarate is converted into tenofovir by diester hydrolysis in the intestinal lumen and plasma, followed by internalization into cells by endocytosis and subsequent phosphorylation into tenofovir diphosphate. Tenofovir diphosphate competes with the natural substrate dATP for incorporation into viral DNA by reverse transcriptase of human immunodeficiency virus (HIV). The substituted DNA-tenofovir diphosphate molecule prevents further DNA elongation, and consequently impairs viral replication and propagation. This agent prevents HIV from reproducing in uninfected cells only. Tenofovir also exhibits activity against the hepatitis B virus (HBV). ( NCI )] (UMLS (NCI) C1099776) TDF;
Tenofovir DF;
Tenofovir Disoproxil Fumarate;
TENOFOVIR DISOPROXIL FUMARATE PREPARATION;
=Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =TENOFOVIR;
Unclassified Ingredients =TENOFOVIR DISOPROXIL FUMARATE 300 MG | - 2170. A Disintegrin and Metalloprotease with Thrombospondin Motifs-1
- [A disintegrin and metalloproteinase with thrombospondin motifs-1 (ADAMTS-1), encoded by the ADAMTS1 gene is a member of the ADAMTS protein family. It cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors. It has anti-angiogenic activity and inhibits endothelial cell proliferation. ADAMTS1 may be associated with various inflammatory processes as well as development of cancer cachexia. It is likely to be necessary for normal growth, fertility, and organ morphology and function. ADAMTS1 is secreted and associated with the extracellular matrix. The Spacer Domain and the TSP Type-1 Domains are important for a tight interaction with the extracellular matrix. ADAMTS1 is expressed as a 110-kD protein, an 85-kD protein after cleavage at the subtilisin site, or as a 67-kD protein, which is most abundant, generated by an additional processing event. (From LocusLink, Swiss_Prot and NCI) ( NCI )] (UMLS (NCI) C1307941) A Disintegrin And Metalloproteinase With Thrombospondin Motifs 1;
ADAMTS1;
ADAM-TS1;
METH-1 =Amino Acid, Peptide, or Protein; Enzyme |
- 2121. 9-(2-phophonylmethoxyethyl)adenine
- [an adenine analog, antiviral agent; used for treating hepatitis, HIV and African swine fever virus infections. ( CSP )] (UMLS (CSP) C0050175) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =[AM800] ANTIVIRALS;
Reverse Transcriptase Inhibitor;
adenine analog;
Unclassified Ingredients =Adefovir Dipivoxil;
| - 2171. A Disintegrin and Metalloprotease with Thrombospondin Motifs-9
- [A disintegrin and metalloproteinase with thrombospondin motifs-9 (ADAMTS9), encoded by the ADAMTS9 gene, is a member of the ADAMTS protein family. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This enzyme contains four C-terminal TS motifs. The spacer domain and the TSP Type-1 domains are important for a tight interaction with the extracellular matrix. The precursor is cleaved by a furin endopeptidase. Two isoforms, a long form and a short form, may be produced by alternative splicing. ADAMTS9 is secreted and associated with the extracellular matrix. It is highly expressed in all fetal tissues and expressed slightly in adult ovary, pancreas, heart, kidney, lung, placenta, spinal cord and brain. (From LocusLink, Swiss_Prot and NCI) ( NCI )] (UMLS (NCI) C1257533) A Disintegrin and Metalloproteinase with Thrombospondin Motifs-9;
ADAMTS9;
ADAM-TS9 =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 2122. 9-AC
- [An anticancer drug that belongs to the family of drugs called topoisomerase inhibitors. ( NCI )] (UMLS (NCI) C0214192) =Organic Chemical; Pharmacologic Substance ;
| - 2172. A Disintegrin and Metalloproteinase Domain 11 Gene
- [This gene plays a role in cell-cell and cell-matrix interactions. ( NCI )] (UMLS (NCI) C1332015) ADAM11;
ADAM11 Gene;
=Gene or Genome ;
|
- 2123. 9-AC/G-CSF
- (UMLS (NCI) C0281574) =Therapeutic or Preventive Procedure
| - 2173. A Disintegrin and Metalloproteinase Domain 11 Protein
- [This protein is a member of the ADAM protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. (LocusLink) ( NCI )] (UMLS (NCI) C1332016) ADAM11;
ADAM11 Protein;
Metalloproteinase-Like, Disintegrin-Like and Cysteine-Rich Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 2124. 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione
- [The acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. ( NCI )] (UMLS (NCI) C0040866) =Steroid; Pharmacologic Substance ;
=(11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione;
[DE200] ANTI-INFLAMMATORY, TOPICAL;
[NT200] ANTI-INFLAMMATORIES, NASAL;
[OR900] DENTAL AND ORAL AGENTS, TOPICAL OTHER;
[RE101] ANTI-INFLAMMATORIES, INHALATION;
=(11beta,16alpha)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione;
TRIAMCINOLONE ACETONIDE PWDR;
TRIAMCINOLONE ACETONIDE 0.1 %;
TRIAMCINOLONE ACETONIDE 40 MG/ML;
TRIAMCINOLONE ACETONIDE 100 MCG/ACTUAT;
TRIAMCINOLONE ACETONIDE 10 MG/ML;
TRIAMCINOLONE ACETONIDE 55 MCG/ACTUAT;
TRIAMCINOLONE ACETONIDE 2.5 MG/GM;
TRIAMCINOLONE ACETONIDE 50 MCG/ACTUAT;
TRIAMCINOLONE ACETONIDE 3 MG/ML;
TRIAMCINOLONE ACETONIDE 3.3 MG/50GM;
TRIAMCINOLONE ACETONIDE 0.025 %;
TRIAMCINOLONE ACETONIDE 0.147 MG/GM;
TRIAMCINOLONE ACETONIDE 0.5 %;
TRIAMCINOLONE ACETONIDE 1 MG/GM | - 2174. A Disintegrin and Metalloproteinase Domain 15
- [MDC-15; ADAM-15; metargidin. Member of a sequence-related family of cysteine-rich membrane proteins containing metalloproteinase-like and disintegrin-like domains; contains an RGD sequence in its disintegrin domain. ( NCI )] (UMLS (NCI) C1313290) ADAM15;
EC 3.4.24.-;
MDC15;
Metalloprotease-RGD-Disintegrin Protein;
Metalloproteinase-Like Disintegrin-Like and Cysteine-Rich Protein 15;
Metargidin =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 2125. 9-amino-20(S)-camptothecin
- (UMLS (NCI) C0950849) 9-Amino-20-(S)-camptothecin =Organic Chemical; Pharmacologic Substance
| - 2175. A Disintegrin and Metalloproteinase Domain 15 Gene
- [This gene is involved in the restructuring of the mesangial matrix. ( NCI )] (UMLS (NCI) C1332017) ADAM15;
ADAM15 Gene;
=Gene or Genome ;
|
- 2126. 9-Beta-D-arabinofuranosyl-9H-purine-6-amine Monohydrate
- [A nucleoside antibiotic isolated from the bacterium Streptomyces antibioticus with antineoplastic activity. Vidarabine inhibits DNA polymerase, resulting in the inhibition of DNA replication in tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0042646) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=adenosine;
arabinonucleoside;
[OP203] ANTIVIRALS, TOPICAL OPHTHALMIC;
=2-Fluoro-9-beta-arabinofuranosyladenine;
VIDARABINE 3 %;
| - 2176. A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, Alpha, Converting Enzyme) Gene
- [This gene plays a role in the cleavage of membrane proteins, resulting in the release of their extracellular domains from cells. ( NCI )] (UMLS (NCI) C1412186) ADAM17;
ADAM17 Gene =Gene or Genome ;
|
- 2127. 9-Chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate
- [A glucocorticoid receptor agonist with metabolic, anti-inflammatory, and immunosuppressive activity. Clocortolone pivalate exerts its effect by interacting with specific intracellular receptors and subsequently binds to DNA to modify gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. ( NCI )] (UMLS (NCI) C0055900) =Steroid; Pharmacologic Substance; Hormone =Fluocortolone;
CLOCORTOLONE =CLOCORTOLONE PIVALATE 0.1 % | - 2177. A Disintegrin-Like and Metalloprotease (Reprolysin Type) with Thrombospondin Type 1 Motif, 1 Gene
- [This gene is involved in the inhibition of angiogenesis and cell proliferation. ( NCI )] (UMLS (NCI) C1332018) ADAMTS1;
ADAMTS1 Gene;
=Gene or Genome ;
|
- 2128. 9-cis-Retinoic Acid/Interferon Alfa
- [A combination drug therapy. ( NCI )] (UMLS (NCI) C0338247) =Therapeutic or Preventive Procedure
| - 2178. A Disintegrin-Like and Metalloprotease (Reprolysin Type) with Thrombospondin Type 1 Motif, 9 Gene
- [This gene plays a role in apoptosis and development. ( NCI )] (UMLS (NCI) C1332020) ADAMTS9;
ADAMTS9 Gene;
=Gene or Genome ;
|
- 2129. 9-cis-Retinoic Acid/Tamoxifen
- (UMLS (NCI) C0338279) =Therapeutic or Preventive Procedure ;
| - 2179. A follow up visit from a previous appointment
- (UMLS (HL7) C1548402) =Idea or Concept =Appointment reason codes;
|
- 2130. 9-Ethyl 6-Mercaptopurine
- [A synthetic alkyl derivative prodrug of the antineoplastic agent 6-mercaptopurine (6-MP). In vivo, 9-ethyl 6-mercaptopurine appears to be converted to 6-MP, which substitutes for the normal nucleoside and fraudulently incorporates into DNA and inhibits de novo purine synthesis, thereby inducing cell death. (NCI04) ( NCI )] (UMLS (NCI) C0626019) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 2180. A generic substitution was dispensed.
- (UMLS (HL7) C1549557) =Idea or Concept =Substitution Status;
|
- 2131. 9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
- [A synthetic glucocorticoid receptor agonist with metabolic, anti-inflammatory and immunosuppressive activity. Desoximetasone activates specific intracellular receptors, which bind to distinct sites on DNA to modify gene transcription. This results in an induction of the synthesis of anti-inflammatory proteins and suppression of the synthesis of inflammatory mediators. This leads to an overall reduction in chronic inflammation and autoimmune reactions. Desoximetasone is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. ( NCI )] (UMLS (NCI) C0011707) =Steroid; Pharmacologic Substance; Hormone =(11Beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione;
Pregnadienediols;
[DE200] ANTI-INFLAMMATORY, TOPICAL;
=DESOXIMETASONE 0.25 %;
DESOXIMETASONE 0.5 %;
DESOXIMETASONE 0.05 % | - 2181. A Kinase (PRKA) Anchor Protein (Gravin) 12 Gene
- [This gene plays a role in signal transduction and angiogenesis. ( NCI )] (UMLS (NCI) C1332070) AKAP12;
AKAP12 Gene;
=Gene or Genome |
- 2132. 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate
- [The acetate salt form of fluorometholone, a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Fluorometholone acetate exerts its effect by interacting with cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. ( NCI )] (UMLS (NCI) C0724587) Fluorometholone Acetate;
FLUOROMETHOLONE ACETATE PREPARATION =Steroid; Pharmacologic Substance ;
=FLUOROMETHOLONE;
=FLUOROMETHOLONE ACETATE 0.1 %;
| - 2182. A Kinase (PRKA) Anchor Protein (Yotiao) 9
- [The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in many isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. (from LocusLink) ( NCI )] (UMLS (NCI) C0672770) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 2133. 9-NC
- [An alkaloid drug belonging to a class of anticancer agents called topoisomerase inhibitors. ( NCI )] (UMLS (NCI) C0213800) =Organic Chemical; Pharmacologic Substance ;
| - 2183. A Kinase (PRKA) Anchor Protein (Yotiao) 9 Gene
- [This gene plays a role in signal transduction and modulates synaptic transmission. ( NCI )] (UMLS (NCI) C1332072) AKAP9;
AKAP9 Gene;
=Gene or Genome |
- 2134. 9-Nitro-20 (S-)Camptothecin
- [A semisynthetic agent related to camptothecin with potent antitumor and antiviral properties. Rubitecan binds to and inhibits the enzyme topoisomerase I and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells; this agent also prevents repair of reversible single-strand DNA breaks. (NCI04) ( NCI )] (UMLS (NCI) C0213799) =Organic Chemical; Pharmacologic Substance ;
| - 2184. A Kinase (PRKA) Anchor Protein 12
- [The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. (from LocusLink) ( NCI )] (UMLS (NCI) C0289793) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 2135. 9-[(3-Methyl-2-butenyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one
- (UMLS (NCI) C0063435) =Organic Chemical; Pharmacologic Substance
| - 2185. A Kinase (PRKA) Anchor Protein 13 Gene
- [This gene is involved in signal transduction and protein trafficking. ( NCI )] (UMLS (NCI) C1332071) AKAP13;
AKAP13 Gene;
=Gene or Genome |
- 2136. 90 kDa Ribosomal Protein S6 Kinase 5
- [Widely expressed in heart, brain, placenta, lung, kidney, and liver by human RPS6KA5 Gene (S6 Ser/Thr Kinase Family), predominantly nuclear 802-aa 90-kDa Ribosomal Protein S6 Kinase Alpha 5 is a Ser/Thr kinase that associates with, phosphorylates, and controls NF-Kappa-B p65 subunit (RELA) transcriptional activity in response to TNF. RPS6KA5 activity requires the presence of both kinase domains. Likely activated by ERK1/2 and p38 Ser/Thr phosphorylations, RPS6KA5 transiently dissociates from complexes with ERK1/2 following mitogenic stimulation and may mediate growth factor and stress induced activation of transcription factor CREB. RPS6KA5 also associates with MAPK14/p38alpha. (NCI) ( NCI )] (UMLS (NCI) C0913240) Mitogen- and Stress-Activated Protein Kinase 1;
Nuclear Mitogen-and Stress-Activated Protein Kinase-1;
Ribosomal Protein S6 Kinase 90kD Polypeptide 5;
Ribosomal Protein S6 Kinase Alpha 5;
RLSK;
RPS6KA5;
RSK-Like Protein Kinase;
=Amino Acid, Peptide, or Protein; Enzyme ;
| - 2186. A Kinase Anchor Protein 13
- [Encoded by human oncogene AKAP13 Gene, 424-amino acid 49 kD A Kinase Anchor Protein 13 is a signal transduction RHO/RAC GEF involved in cytoskeletal organization and cell cycle progression. Alpha helical hydrophilic LBC is conserved among vertebrates and expressed in skeletal muscle, heart, lung, and hematopoietic cells. It contains phosphorylation sites, N-terminal DH and PH domains, and an N-terminal EF-hand motif. LBC binds to PKA RII tethering it near substrates. AKAP13 stimulates RHO/RAC, but not CDC42 or RAS. In ovary, placenta, breast, and testis, 170 kD BRX contains a LBC region preceded by 3 novel regions; C-terminal regions 4 and 5 bind to the ESR1 ligand-binding domain. BRX also binds RXR, PPAR, and THR. Chimeric onco-LBC lacks the C-terminus, which promotes transforming activity. Proto-LBC is membrane bound; onco-LBC is cytosolic. (OMIM, Swiss-Prot, and NCI) ( NCI )] (UMLS (NCI) C1318045) AKAP13;
A-Kinase (PRKA) Anchor Protein 13;
BRX;
HT31;
LBC;
P47 =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 2137. 90 Y-B3
- [A radioimmunoconjugate of monoclonal antibody (MoAb) B3 conjugated with isotope yttrium 90. MoAb B3 is a murine MoAb that recognizes a Lewis Y carbohydrate antigen present on the surface of many carcinomas. This radioimmunoconjugate emits beta particles that causes cytotoxicity in tumor cells and has both diagnostic and therapeutic uses. ( NCI )] (UMLS (NCI) C0935761) MOAB B3, Yttrium Y 90;
Y 90 Monoclonal Antibody B3;
Y90-B3;
Yttrium Y 90 Monoclonal Antibody B3 =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor | - 2187. A kinase anchoring protein
- [class of proteins that target cAMP dependent protein kinase to various sites within the cell. ( CSP )] (UMLS (CSP) C0872014) AKAP;
=Amino Acid, Peptide, or Protein; Biologically Active Substance =binding protein;
|
- 2138. 908
- [The calcium salt form of fosamprenavir, prodrug of amprenavir, and a human immunodeficiency virus (HIV) protease inhibitor with antiviral property. Fosamprenavir is converted to amprenavir by cellular phosphatases in the epithelial cells of the intestine. Then amprenavir binds to the active site of HIV-1 protease, thereby preventing the proteolytic cleavage of viral Gag-Pol polypeptide into individual functional proteins, thereby leading to the formation of immature non-infectious viral particles. ( NCI )] (UMLS (NCI) C1321660) Fosamprenavir Calcium =Organophosphorus Compound; Pharmacologic Substance
| - 2188. A previously unscheduled walk-in visit
- (UMLS (HL7) C1548404) =Intellectual Product =Appointment reason codes;
|
- 2139. 90Sr
- [A radioactive isotope of the heavy metal strontium, Strontium-90 is a by-product of uranium and plutonium fission. SR-90 is linked to bone, and other, cancers. Acting chemically in vivo like calcium, it tends to concentrate in bones and teeth. Used as a radioactive tracer in medical and agricultural studies, controlled amounts of strontium-90 have also been used as a treatment for bone cancer. (NCI04) ( NCI )] (UMLS (NCI) C0303547) =Element, Ion, or Isotope
| - 2189. A product from a controlled/non-related inventory was evaluated
- (UMLS (HL7) C1546983) =Idea or Concept =Product source;
|
- 2140. 90Y
- [Radioactive isotope of yttrium. A beta/gamma-emitter with a half life of 2.7 days. ( NCI )] (UMLS (CSP) C0303596) =Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope
| - 2190. A product from a reserve sample was evaluated
- (UMLS (HL7) C1546984) =Idea or Concept =Product source;
|
- 2141. 90Y-DOTA-Biotin
- [A radioactive substance (yttrium-90) joined by a large chemical link (DOTA) to biotin, a vitamin. ( NCI )] (UMLS (NCI) C0677849) =Organic Chemical; Pharmacologic Substance
| - 2191. A product from the same lot as the actual product involved was evaluated
- (UMLS (HL7) C1546982) =Idea or Concept =Product source;
|
- 2142. 90% + BDY BRN/10-19% 3RD
- [ ] (UMLS (ICD9CM) C0161383) =Injury or Poisoning
| - 2192. A race-based population
- (UMLS (HL7) C1548149) =Idea or Concept =Nature of Abnormal Testing;
|
- 2143. 90% + BDY BRN/20-29% 3RD
- [ ] (UMLS (ICD9CM) C0161384) =Injury or Poisoning
| - 2193. A request for a tentative (e.g., "penciled in") appointment
- (UMLS (HL7) C1548407) =Idea or Concept =Appointment Type Codes;
|
- 2144. 90% + BDY BRN/30-39% 3RD
- [ ] (UMLS (ICD9CM) C0161385) =Injury or Poisoning
| - 2194. A request to add a completed appointment, used to maintain records of completed appointments that did not appear in the schedule (e.g., STAT, walk-in, etc.)
- (UMLS (HL7) C1548405) =Intellectual Product =Appointment Type Codes;
|
- 2145. 90% + BDY BRN/3D DEG NOS
- [ ] (UMLS (ICD9CM) C0161382) =Injury or Poisoning
| - 2195. A routine check-up, such as an annual physical
- (UMLS (HL7) C1548400) =Intellectual Product =Appointment reason codes;
|
- 2146. 90% + BDY BRN/40-49% 3RD
- [ ] (UMLS (ICD9CM) C0161386) =Injury or Poisoning
| - 2196. A sex-based population
- (UMLS (HL7) C1548150) =Idea or Concept =Nature of Abnormal Testing;
|
- 2147. 90% + BDY BRN/50-59% 3RD
- [ ] (UMLS (ICD9CM) C0161387) =Injury or Poisoning
| - 2197. A therapeutic substitution was dispensed.
- (UMLS (HL7) C1549559) =Idea or Concept =Substitution Status;
|
- 2148. 90% + BDY BRN/60-69% 3RD
- [ ] (UMLS (ICD9CM) C0161388) =Injury or Poisoning
| - 2198. A'ananin
- (UMLS (HL7) C1555606) Ahahnelin;
=Language =ArapahoGrosVentre;
|
- 2149. 90% + BDY BRN/70-79% 3RD
- [ ] (UMLS (ICD9CM) C0161389) =Injury or Poisoning
| - 2199. A-43818
- (UMLS (NCI) C0701460) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone
|
- 2150. 90% + BDY BRN/80-89% 3RD
- [ ] (UMLS (ICD9CM) C0161390) =Injury or Poisoning
| - 2200. A-4828
- (UMLS (NCI) C0149248) =Organic Chemical; Pharmacologic Substance
|
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