- 1601. 3RD DEG BURN KNEE
- [ ] (UMLS (ICD9CM) C0161294) =Injury or Poisoning
| - 1651. 4'-Deoxyadriamycin
- [A synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin. Esorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent exhibits less cardiotoxicity than the parent antibiotic doxorubicin, but may cause severe myelosuppression. (NCI04) ( NCI )] (UMLS (NCI) C0047760) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
|
- 1602. 3RD DEG BURN LEG NOS
- [ ] (UMLS (ICD9CM) C0161289) =Injury or Poisoning
| - 1652. 4'-Deoxyadriamycin Hydrochloride
- (UMLS (NCI) C0955070) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 1603. 3RD DEG BURN LEG-MULT
- [ ] (UMLS (ICD9CM) C0161296) =Injury or Poisoning
| - 1653. 4'-Deoxyepivincristine
- [A vinca alkaloid compound and semi-synthetic vincristine derivative with antineoplastic activity. Vinepidine binds to and stabilizes tubulin, thereby preventing tubulin polymerization and depolymerization, which result in microtubule assembly and disassembly, respectively. Treated cells are unable to complete mitosis process and are arrested in the metaphase, thereby leading to an inhibition of cell growth. ( NCI )] (UMLS (NCI) C0078255) =Organic Chemical; Pharmacologic Substance ;
|
- 1604. 3RD DEG BURN LIP
- [ ] (UMLS (ICD9CM) C0161070) =Injury or Poisoning
| - 1654. 4'-Methylgenistein
- [An isoflavone found in soy products. Soy isoflavones are being studied to see if they help prevent cancer. ( NCI )] (UMLS (NCI) C0053622) =Organic Chemical; Pharmacologic Substance ;
|
- 1605. 3RD DEG BURN LOW LEG
- [ ] (UMLS (ICD9CM) C0161293) =Injury or Poisoning
| - 1655. 4, 8-Ethenopyrrolo[3',4':3,4]cyclobut[1,2-f]isoindole-1,3,5,7(2H, 6H)tetrone, octahydro-
- [A bisdioxopiperazines analog with antineoplastic activity. Mitinomide inhibits topoisomerase II and slowly promotes DNA-interstrand cross-linking, thereby inhibiting DNA repair, RNA and protein synthesis. This agent acts without increasing topoisomerase II-DNA covalent cleavable complex formation, as do most topoisomerase inhibitors. (NCI04) ( NCI )] (UMLS (NCI) C0066593) =Organic Chemical; Pharmacologic Substance ;
|
- 1606. 3RD DEG BURN MULT FINGER
- [ ] (UMLS (ICD9CM) C0161235) =Injury or Poisoning
| - 1656. 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol]
- [A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. ( MSH )] (UMLS (NCI) C0028347) =Organic Chemical; Pharmacologic Substance ;
=catechol;
=MASOPROCOL;
|
- 1607. 3RD DEG BURN MULT SITE
- [ ] (UMLS (ICD9CM) C0161318) =Injury or Poisoning
| - 1657. 4,4'-(3H-2,1-Benzoxathiol-3-ylidene)bis(2-bromo-3-methyl-6-(1-met-hylethyl)phenol) S,S-dioxide
- [A dye used as an indicator in determining pH. Bromthymol blue is a weak acid. It can be in acid or base form, depending on the pH of the solution. This reagent is yellow in acidic solutions, blue in basic solutions and green in neutral solution. ( NCI )] (UMLS (NCI) C0006251) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid
|
- 1608. 3RD DEG BURN NECK
- [ ] (UMLS (ICD9CM) C0161075) =Injury or Poisoning
| - 1658. 4,4'-(Dimethylamino)benzophenone
- [A white to green colored leaflet material that emits toxic fumes of nitrogen oxides when heated to decomposition. Michler's ketone is used as a chemical intermediate in making dyes and pigments, particularly auramine derivatives, for dyeing paper, textiles, and leather. Exposure to Michler's ketone affects the central nervous system. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0066505) =Organic Chemical; Hazardous or Poisonous Substance
|
- 1609. 3RD DEG BURN NOSE
- [ ] (UMLS (ICD9CM) C0161072) =Injury or Poisoning
| - 1659. 4,4'-Bis(dimethylamino)diphenylmethane
- [A yellow colored, combustible leaflet material that emits toxic fumes of nitrogen oxides when heated to decomposition. Michler's base is used as a chemical intermediate in the manufacture of dyes and for its hydrochloric salt and is also used as an analytical reagent in the determination of lead. Exposure to Michler's base irritates the skin and eyes and can lead to methemoglobinemia and respiratory tract distress. Michler's base is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0067320) =Organic Chemical; Pharmacologic Substance ;
|
- 1610. 3RD DEG BURN PALM
- [ ] (UMLS (ICD9CM) C0161237) =Injury or Poisoning
| - 1660. 4,4'-DADPE
- [A colorless, odorless, combustible aromatic amine that emits toxic fumes of nitrogen oxides when heated to decomposition. 4,4'-Oxydianiline is used in industry in the manufacture of polyimide and polyester resins. Exposure to this substance is irritating to the eyes, skin and respiratory-tract. 4,4'-Oxydianiline is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0057642) =Organic Chemical; Pharmacologic Substance ;
|
- 1611. 3RD DEG BURN SCALP
- [ ] (UMLS (ICD9CM) C0161073) =Injury or Poisoning
| - 1661. 4,4'-Diaminodiphenylsulfide
- [A brown to violet colored solid aromatic amine that emits toxic fumes of nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen and sulfur oxides when heated to decomposition. 4,4'-Thiodianiline is primarily used as a chemical intermediate in the production of certain dyes. Exposure to this substance is irritating to the respiratory tract and can result in methemoglobinemia causing headache, dizziness, weakness and can lead to shortness of breath, collapse and even death. 4,4'-Thiodianiline is a possible mutagen and is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0047830) =Organic Chemical; Pharmacologic Substance ;
|
- 1612. 3RD DEG BURN SCAPULA
- [ ] (UMLS (ICD9CM) C0161181) =Injury or Poisoning
| - 1662. 4,4'-Diamonophenyl
- [A grayish-red, yellowish or white colored, very toxic, crystalline aromatic amine that darkens when exposed to air and light. Benzidine has been widely used for the detection of blood and as a reagent in the manufacture of dyes. Ingestion of benzidine causes cyanosis, headache, mental confusion, nausea and vomiting. Its use is now limited because of strong association between exposure to benzidine and an increased risk of bladder cancer in humans. (NCI05) ( NCI )] (UMLS (NCI) C0005047) =Organic Chemical; Hazardous or Poisonous Substance
|
- 1613. 3RD DEG BURN SHOULDER
- [ ] (UMLS (ICD9CM) C0161180) =Injury or Poisoning
| - 1663. 4,4'-Dichloro-2,2'-methylenediphenol
- [A nontoxic laxative vermicide of chlorinated phenol compound. Dichlorophen is used as a veterinary fungicide, anthelmintic, and anti-protozoan, as well as an ingredient in antimicrobial soaps and shampoos. This agent probably acts by increasing the clearing of intestinal contents, thereby eradicating tapeworm infections from the intestines. ( NCI )] (UMLS (NCI) C0012082) =Organic Chemical; Pharmacologic Substance
|
- 1614. 3RD DEG BURN THIGH
- [ ] (UMLS (ICD9CM) C0161295) =Injury or Poisoning
| - 1664. 4,4'-Dichloro-3-(trifluoromethyl)-carbanilide
- [A synthetic, carbanilide compound with antiseptic activity. Cloflucarban is used as disinfectant and is found in antimicrobial soaps and deodorants. ( NCI )] (UMLS (NCI) C0055912) =Organic Chemical; Pharmacologic Substance ;
|
- 1615. 3RD DEG BURN THUMB
- [ ] (UMLS (ICD9CM) C0161234) =Injury or Poisoning
| - 1665. 4,4'-Methylenebisbenzenamine
- [A yellowish to brownish colored crystalline solid aromatic amine with a faint amine-like odor that is unstable in the presence of light or air and emits toxic fumes of aniline and nitrogen oxides when heated to decomposition. 4,4'-Methylenedianiline is primarily used in industry as a chemical intermediate in the production of 4,4-methylenedianiline diisocyanates and polyisocyanates, but is also used as a cross-linking agent for the determination of tungsten and sulfates, and as a corrosion inhibitor. Exposure to this substance irritates the skin and eyes and causes liver damage. 4,4'-Methylenedianiline is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0047805) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 1616. 3RD DEG BURN TOE
- [ ] (UMLS (ICD9CM) C0161290) =Injury or Poisoning
| - 1666. 4,4'-Sulfonylbis[benzenamine]
- [USP lists as a suppressant of dermatitis herpetiformis. ( CSP )] (UMLS (NCI) C0010980) =Organic Chemical; Pharmacologic Substance =Sulfone;
antibacterial agent;
[AM900] ANTI-INFECTIVES, OTHER;
=DAPSONE 100 MG;
DAPSONE 25 MG |
- 1617. 3RD DEG BURN TRUNK NEC
- [ ] (UMLS (ICD9CM) C0161130) =Injury or Poisoning
| - 1667. 4,4'-[(4-Imino-2,5-cyclohexadien-1-ylidene)methylene]bisbenzenamine Monohydrochloride
- [A green, crystalline, solid dye that is one of the major components of magenta. Basic fuchsin is primarily used for bacterial identification, but is also used as a dye in textiles, leather, and printing inks. Exposure to basic fuchsin is irritating to the eyes and skin. The substance is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0073578) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid =Unclassified Ingredients;
Inactive Ingredient Preparations =BASIC FUCHSIN 0.3 GM;
BASIC FUCHSIN 0.53 %;
|
- 1618. 3RD DEG BURN TRUNK NOS
- [ ] (UMLS (ICD9CM) C0840808) Full-thickness skin loss due to burn [third degree NOS] of unspecified site of trunk =Injury or Poisoning
| - 1668. 4,5-alpha-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one Hydrochloride
- [The hydrochloride salt form of oxymorphone, a semisynthetic opioid with a potent analgesic property. Oxymorphone hydrochloride binds to and activates opiate receptors, specifically mu-receptors, in the central nervous system (CNS). This results in sedation, analgesia, decreased gastrointestinal motility, and respiratory depression. ( NCI )] (UMLS (NCI) C0282275) =Organic Chemical; Pharmacologic Substance =OXYMORPHONE;
=OXYMORPHONE HYDROCHLORIDE 1 MG/ML;
OXYMORPHONE HYDROCHLORIDE 1.5 MG/ML;
OXYMORPHONE HYDROCHLORIDE 5 MG |
- 1619. 3RD DEG BURN UPPER ARM
- [ ] (UMLS (ICD9CM) C0161178) =Injury or Poisoning
| - 1669. 4,5-Diphenyl-2-oxazolepropionic Acid
- [A nonsteroidal anti-inflammatory drug (NSAID) derivative of oxazole-propionic acid with analgesic and antipyretic properties. As a first generation NSAID inhibitor, oxaprozin binds to and inactivates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory prostaglandins. When inhibiting COX-2, this agent may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. (NCI04) ( NCI )] (UMLS (NCI) C0069739) =Organic Chemical; Pharmacologic Substance =Propionic Acids;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC =OXAPROZIN 600 MG;
|
- 1620. 3RD DEG BURN W LOSS-BACK
- [ ] (UMLS (ICD9CM) C0375679) =Injury or Poisoning
| - 1670. 4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
- [A semi-synthetic, morphine-like opioid alkaloid with analgesic activity. Oxycodone exerts its analgesic activity by binding to the mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opioids. Binding of the opiate receptor stimulates the exchange of GTP for GDP on the G-protein complex and inhibits adenylate cyclase, thereby preventing cAMP production. Subsequently, the release of nociceptive neurotransmitters, such as substance P, gamma-aminobutyric acid (GABA), dopamine, acetylcholine, and noradrenaline, is inhibited. Oxycodone also inhibits the release of vasopressin, somatostatin, insulin, and glucagon. In addition, oxycodone closes N-type voltage-gated calcium channels and opens G-protein-coupled inwardly rectifying potassium channels resulting in hyperpolarization and reduction of neuronal excitability. ( NCI )] (UMLS (NCI) C0030049) =Organic Chemical; Pharmacologic Substance =[CN101] OPIOID ANALGESICS;
codeine =4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Hydrochloride;
Oxycodone Terephthalate;
4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Hydrochloride;
Oxycodone Terephthalate;
OXYCODONE 5 MG;
|
- 1621. 3RD DEG BURN W LOSS-CHIN
- [ ] (UMLS (ICD9CM) C0161093) =Injury or Poisoning
| - 1671. 4,5-Trihydroxybenzylidene malononitrile
- [A member of the tyrphostin family of tyrosine kinase inhibitors that competitively binds and inhibits epidermal growth factor receptor and GTPase activity of transducin and induces apoptosis in human leukemic cell lines. (NCI) ( NCI )] (UMLS (NCI) C0213654) =Organic Chemical; Pharmacologic Substance
|
- 1622. 3RD DEG BURN W LOSS-EAR
- [ ] (UMLS (ICD9CM) C0161090) =Injury or Poisoning
| - 1672. 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Hydrochloride
- [The hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism. ( NCI )] (UMLS (NCI) C0282274) =Organic Chemical; Pharmacologic Substance =4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one;
=OXYCODONE HYDROCHLORIDE 5 MG;
OXYCODONE HYDROCHLORIDE 20 MG/ML;
OXYCODONE HYDROCHLORIDE 5 MG/5ML;
OXYCODONE HYDROCHLORIDE 20 MG;
OXYCODONE HYDROCHLORIDE 80 MG;
OXYCODONE HYDROCHLORIDE 160 MG;
OXYCODONE HYDROCHLORIDE 10 MG;
OXYCODONE HYDROCHLORIDE 40 MG;
OXYCODONE HYDROCHLORIDE 15 MG;
OXYCODONE HYDROCHLORIDE 2.5 MG;
OXYCODONE HYDROCHLORIDE 7.5 MG;
OXYCODONE HYDROCHLORIDE 30 MG;
OXYCODONE HYDROCHLORIDE 2.25 MG;
OXYCODONE HYDROCHLORIDE 4.5 MG;
|
- 1623. 3RD DEG BURN W LOSS-EYE
- [ ] (UMLS (ICD9CM) C0161091) =Injury or Poisoning
| - 1673. 4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride
- [The hydrochloride salt form of minocycline, a broad-spectrum, semi-synthetic tetracycline antibiotic with antimicrobial properties. Minocycline hydrochloride exerts its bacteriostatic effect by binding to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to mRNA on the ribosomes during elongation step of protein translation. This leads to an inhibition of bacterial protein synthesis and consequently cell growth. ( NCI )] (UMLS (NCI) C0026186) =Organic Chemical; Antibiotic =MINOCYCLINE;
=MINOCYCLINE HYDROCHLORIDE 50 MG;
MINOCYCLINE HYDROCHLORIDE 100 MG;
MINOCYCLINE HYDROCHLORIDE 75 MG;
MINOCYCLINE HYDROCHLORIDE 50 MG/5ML;
MINOCYCLINE HYDROCHLORIDE 1 MG |
- 1624. 3RD DEG BURN W LOSS-LIP
- [ ] (UMLS (ICD9CM) C0161092) =Injury or Poisoning
| - 1674. 4,9-Dimethoxy-7H-furo[3,2-g][1]benzopyran-7-one
- (UMLS (NCI) C0064041) =Organic Chemical
|
- 1625. 3RD DEG BURN W LOSS-NECK
- [ ] (UMLS (ICD9CM) C0161097) =Injury or Poisoning
| - 1675. 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide
- [A sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particularly used in the treatment of pulmonary arterial hypertension. ( NCI )] (UMLS (NCI) C0252643) =Organic Chemical; Pharmacologic Substance =[CV900] CARDIOVASCULAR AGENTS, OTHER;
Unclassified Ingredients =BOSENTAN 125 MG;
BOSENTAN 62.5 MG;
|
- 1626. 3RD DEG BURN W LOSS-NOSE
- [ ] (UMLS (ICD9CM) C0161094) =Injury or Poisoning
| - 1676. 4-(1-Methylethenyl)-1-cyclohexene-1-carboxylic Acid
- (UMLS (NCI) C0211503) =Organic Chemical
|
- 1627. 3RD DEG BURN WRIST
- [ ] (UMLS (ICD9CM) C1443010) Full-thickness skin loss due to burn [third degree NOS] of wrist;
=Injury or Poisoning ;
| - 1677. 4-(3'-bromoanilino)-6,7-dimethoxyquinazoline
- [A protein tyrosine kinase inhibitor that has specific activity for the epidermal growth factor receptor. (NCI) ( NCI )] (UMLS (NCI) C0258113) =Organic Chemical; Pharmacologic Substance
|
- 1628. 3RD DEGREE BURN NOS
- [ ] (UMLS (ICD9CM) C0375688) =Injury or Poisoning
| - 1678. 4-(3-(p-Butoxyphenoxy)propyl)morpholine Hydrochloride
- [The hydrochloride salt form of pramoxine, a morpholine derivative with local anesthetic property. Pramoxine hydrochloride decreases the permeability of the neuronal membrane to sodium ions by reversibly binding to and inhibiting voltage-gated sodium channels. This results in stabilization of the membrane and , thereby inhibiting the ionic fluxes required for membrane depolarization, hence resulting in the failure to initiate a propagated action potential and subsequent conduction blockade. ( NCI )] (UMLS (NCI) C0147008) =Organic Chemical; Pharmacologic Substance =pramocaine;
=PRAMOXINE HYDROCHLORIDE 1 %WW;
PRAMOXINE HYDROCHLORIDE 10 MG/GM;
PRAMOXINE HYDROCHLORIDE 0.1 %;
PRAMOXINE HYDROCHLORIDE 0.5 %;
PRAMOXINE HYDROCHLORIDE 1 % |
- 1629. 3RD DEGREE SUNBURN
- [ ] (UMLS (ICD9CM) C0452001) =Injury or Poisoning
| - 1679. 4-(3Chloro-4-flurophenylamine)-7-methoxy-6(3-(4morpholinyl)quinazoline
- [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors. Also called ZD 1839. ( NCI )] (UMLS (NCI) C1122962) 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-4-morpholin] propoxy];
Gefitinib;
GEFITINIB PREPARATION =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Unclassified Ingredients =GEFITINIB 250 MG |
- 1630. 3rd Operative
- (UMLS (HL7) C1547208) =Idea or Concept =Procedure DRG Type;
| - 1680. 4-(5,6,7,8-Tetrahydroimidazo(1,5-a)pyridin-5-yl)benzonitrile
- [A selective aromatase inhibitor effective in the treatment of estrogen-dependent disease including breast cancer. ( MSH )] (UMLS (NCI) C0117234) =Organic Chemical; Pharmacologic Substance ;
|
- 1631. 3s
- [Supernumerary maxillary right first molar ( HL7V3.0 )] (UMLS (HL7) C1552117) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
| - 1681. 4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile Monohydrochloride
- [A non-steroidal aromatase inhibitor effective in the treatment of estrogen-dependent disease. ( NCI )] (UMLS (NCI) C0917743) Fadrozole Hydrochloride =Organic Chemical; Pharmacologic Substance ;
|
- 1632. 3T3 cell
- [a ubiquitous tissue culture model for nontransformed animal cells; derived from nonneoplastic immortalized fibroblasts. ( CSP )] (UMLS (CSP) C0085087) =Cell ;
=cell line;
| - 1682. 4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
- [A drug that reduces pain. Celecoxib belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is being studied for cancer prevention. ( NCI )] (UMLS (NCI) C0538927) =Organic Chemical; Pharmacologic Substance =sulfonamide;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC =CELECOXIB 100 MG;
CELECOXIB 200 MG;
CELECOXIB 400 MG |
- 1633. 3TC/d4T/IDV
- (UMLS (NCI) C0393010) =Therapeutic or Preventive Procedure
| - 1683. 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide
- [A substance that is being studied as a treatment for pain and other side effects of cancer therapy. It belongs to the family of drugs called COX-2 inhibitors. ( NCI )] (UMLS (NCI) C0913246) Valdecoxib;
VALDECOXIB PREPARATION;
VALDECOXIB UNIDENTIFIED;
=Organic Chemical; Pharmacologic Substance ;
=[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;
Unclassified Ingredients =VALDECOXIB 10 MG;
VALDECOXIB 20 MG |
- 1634. 4
- [Maxillary right second premolar ( HL7V3.0 )] (UMLS (HL7) C0227037) tooth 4 =Body Part, Organ, or Organ Component =Permanent dentition;
| - 1684. 4-(6-Methoxy-2-naphthalenyl)-2-butanone
- [A naphthylalkanone and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activity. Nabumetone is a prodrug that upon hepatic catalysis converts into the active moiety 6-methoxy-2-naphthylacetic acid (6MNA). 6MNA inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of nabumetone. The formation of thromboxane A2, by thromboxane synthase, is also decreased and results in an inhibition of platelet aggregation. ( NCI )] (UMLS (NCI) C0068334) =Organic Chemical; Pharmacologic Substance ;
=Butanones;
[CN104] NONSTEROIDAL ANTI-INFLAMMATORY ANALGESICS =NABUMETONE 750 MG;
NABUMETONE 500 MG;
|
- 1635. 4
- [After a treatment has been approved and is being marketed, it is studied in a phase IV trial to evaluate side effects that were not apparent in the phase III trial. Thousands of people are involved in a phase IV trial. ( NCI )] (UMLS (NCI) C0282462) study IV =Research Activity ;
=clinical trial;
| - 1685. 4-(Acetylamino)-N-(2-aminophenyl)benzamide
- [A substance that is being studied as an anticancer drug in the treatment of non-small cell lung cancer. Also called N-acetyldinaline. ( NCI )] (UMLS (NCI) C0217598) =Organic Chemical; Pharmacologic Substance ;
|
- 1636. 4 aminosalicylic acid
- [antitubercular agent often administered in association with isoniazid. ( CSP )] (UMLS (CSP) C0030125) =Organic Chemical; Pharmacologic Substance ;
=antitubercular agent;
salicylate | - 1686. 4-(all-trans-retino-yl)aminophenol
- [N-(4-hydroxyphenyl)retinamide; a synthetic retinoid used orally as a chemopreventive agent against prostate cancer in men and in women at risk of developing breast cancer; also effective as an antineoplastic agent. ( CSP )] (UMLS (NCI) C0060197) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
Retinoic Acid Agent |
- 1637. 4 hours
- (UMLS (HL7) C1292426) =Temporal Concept ;
=Duration categories;
| - 1687. 4-(Aminomethyl)benzenesulfonamide Monoacetate
- [The acetate salt form of mafenide, a synthetic sulfonamide analog of para-aminobenzoic acid (PABA) with topical anti-infective activity. Mafenide acetate competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, thereby interferes with normal folic acid metabolism. As a result de novo synthesis of pyrimidines, which requires folate metabolites, is impeded and subsequently DNA synthesis is affected. Mafenide acetate is bacteriostatic against many gram-negative and gram-positive organisms, including Pseudomonas aeruginosa and certain strains of anaerobes. ( NCI )] (UMLS (NCI) C0024453) =Organic Chemical; Pharmacologic Substance =MAFENIDE;
[DE101] ANTIBACTERIAL, TOPICAL =MAFENIDE ACETATE 8.5 %;
MAFENIDE ACETATE 50 GM;
|
- 1638. 4 hours post challenge
- (UMLS (HL7) C1547079) =Temporal Concept =Time delay post challenge;
| - 1688. 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide
- [A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. ( NCI )] (UMLS (NCI) C0039644) =Organic Chemical; Antibiotic ;
=[GA303] H.PYLORI AGENTS;
[AM250] TETRACYCLINES =(4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride;
TETRACYCLINE 125 MG/5ML;
TETRACYCLINE 500 MG |
- 1639. 4 hydroxynonenal
- [ ] (UMLS (CSP) C0048297) =Organic Chemical; Pharmacologic Substance
| - 1689. 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone
- [A yellowish crystalline solid nitrosamine that naturally occurs in tobacco products by oxidation and nitrosation of nicotine during the making and smoking of tobacco. 4-Methylnitrosamino-1,3-pyridyl-1-butanone is only used as a research chemical to induce tumorigenesis. This substance is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0047964) =Organic Chemical; Pharmacologic Substance ;
|
- 1640. 4 hydroxyphenylpyruvate dioxygenase
- [An enzyme that catalyzes the conversion of 4-hydroxyphenylpyruvate plus oxygen to homogentisic acid and carbon dioxide. EC 1.13.11.27. ( MSH )] (UMLS (CSP) C0000507) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 1690. 4-(Nitrooxy)butyl 2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetate
- (UMLS (NCI) C0381496) =Organic Chemical; Pharmacologic Substance ;
|
- 1641. 4 minutes post challenge
- (UMLS (HL7) C1547080) =Temporal Concept =Time delay post challenge;
| - 1691. 4-Acridinecarboxamide,9-((2-methoxy-4-((methylsulfonyl)amino)phenyl)amino-N,5-dimethyl
- (UMLS (NCI) C0130561) =Organic Chemical; Pharmacologic Substance ;
|
- 1642. 4 nitroquinoline N oxide
- [A potent mutagen and carcinogen. This compound and its metabolite 4-hydroxyaminoquinoline-1-oxide bind to nucleic acids. It inactivates bacteria but not bacteriophage. (MeSH) ( NCI )] (UMLS (CSP) C0000511) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 1692. 4-Amino-1-beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
- [pyrimidine analog that inhibits DNA methyltransferase, impairing DNA methylation, also an antimetabolite of cytidine, incorporated primarily into RNA; has been used as an antineoplastic agent. ( CSP )] (UMLS (NCI) C0004475) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 1643. 4',5, 7-Trihydroxyisoflavone
- [trihydroxyisoflavone; phytoestrogen found in soy based foods; may have cancer chemoprotective activity. ( CSP )] (UMLS (NCI) C0061202) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =flavone;
| - 1693. 4-Amino-10-methylfolic Acid
- [folic acid antagonist that acts by inhibiting the synthesis of nucleic acids, thymidylate, and protein; used as an antineoplastic in a wide variety of malignancies, and as an antipsoriatic and antirheumatic. ( CSP )] (UMLS (NCI) C0025677) =Organic Chemical; Pharmacologic Substance ;
=4-Aminofolic acid;
[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
[AN000] ANTINEOPLASTICS;
antifolate;
pteridine;
=METHOTREXATE SODIUM |
- 1644. 4',5,7-Trihydroxy-6-methoxyisoflavone
- [An isoflavone from Pueraria thunbergiana, which induces differentiation and apoptosis in cancer cells. (NCI) ( NCI )] (UMLS (NCI) C0769356) Tectorigenin =Organic Chemical
| - 1694. 4-Amino-2(1H)-pyrimidinone
- [2-keto-4-aminopyrimidine, one of the 5 major bases (with adenine, guanine, uracil, and thymine) which are a component of nucleic acids. ( CSP )] (UMLS (NCI) C0010843) =Organic Chemical; Biologically Active Substance =Pyrimidinones;
aminopyrimidine;
nucleobase;
=4-Amino-5-fluoro-2(1H)-pyrimidinone;
1(3-hydroxy-2-phosphonomethoxypropyl) Cytosine |
- 1645. 4',7-Dihydroxyisoflavone
- [An isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein. It has antioxidant and phytoestrogenic properties. (NCI) ( NCI )] (UMLS (NCI) C0057090) =Organic Chemical; Vitamin ;
| - 1695. 4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
- [An imidazoquinolinamine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activates other transcription factors. This may lead to an increase in mRNA levels and subsequent production of cytokines, especially interferon-alpha (INF-a) and other cytokines, thereby enhancing T-helper 1 (Th1) immune responses. In addition, topical application of resiquimod appears to activate Langerhans' cells leading to an enhanced activation of T-lymphocytes. Due to its immunostimulatory activity, this agent may potentially be useful as a vaccine adjuvant. ( NCI )] (UMLS (NCI) C0965594) Resiquimod =Organic Chemical; Pharmacologic Substance ;
|
- 1646. 4'-(9-Acridinylamino)methane-sulfon-m-anisidide
- [An anticancer drug that belongs to the family of drugs called topoisomerase inhibitors. ( NCI )] (UMLS (NCI) C0002699) =Organic Chemical; Pharmacologic Substance ;
| - 1696. 4-Amino-3-(4-chlorophenyl)-butanoic Acid
- [A synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors. It acts at spinal and supraspinal sites, reducing excitatory transmission. (NCI04) ( NCI )] (UMLS (NCI) C0004609) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 1647. 4'-Amino-6-hydroxyflavone
- [A compound that inhibits the Protein-Tyrosine Kinase Activity of p56lck. ( NCI )] (UMLS (NCI) C0644340) =Organic Chemical; Pharmacologic Substance
| - 1697. 4-Amino-3-[[4'-((2,4-Diaminophenyl)azo)(1,1'-Biphenyl)-4-yl]azo]-5-Hydroxy-6-(Phenylazo)- 2,7-Naphthalenedisulfonic Acid, Disodium Salt
- [A Benzidine-based azo dye that is metabolized to free Benzidine in vivo. Direct black 38 is primarily used for the dyeing of textiles, leather and paper. Benzidine and its metabolic derivatives have been detected in the urine of workers exposed to Benzidine-based dyes. Exposure to this dye is strongly associated with the occurrence of bladder cancer. (NCI05) ( NCI )] (UMLS (NCI) C0058437) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
|
- 1648. 4'-Demethylepipodophyllotoxin 9-[4,6-O-ethylidene-beta-D-glucopyranoside
- [glucopyranosyl substituted naphthalene derived from podophyllin; mutagen and immunosuppressant used in combination antineoplastic therapy for several human malignancies. ( CSP )] (UMLS (NCI) C0015133) =Carbohydrate; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Glucosides;
[IM600] IMMUNE SUPPRESSANTS;
Mutagen;
Mayapple Extract;
PODOFILOX =Etoposide Phosphate;
ETOPOSIDE 20 MG/ML;
ETOPOSIDE 50 MG;
ETOPOSIDE 100 MG;
ETOPOSIDE 200 MG;
ETOPOSIDE 500 MG;
| - 1698. 4-Amino-5-fluoro-2(1H)-pyrimidinone
- [fluorinated cytosine analog that is used as an antifungal agent. ( CSP )] (UMLS (NCI) C0016278) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM700] ANTIFUNGALS;
4-Amino-2(1H)-pyrimidinone;
pyrimidine analog;
halocarbon compound =FLUCYTOSINE 250 MG;
FLUCYTOSINE 500 MG;
|
- 1649. 4'-Deoxy-20',20'-difluoro-C'-norvincaleukoblastine
- [A novel fluorinated Vinca alkaloid with antiangiogenic and antitumor activities. Although the exact mechanism of the mitotic block is not clear, vinflunine could induce cell cycle arrest at G2/M phase, and cause a concentration-dependent reduction of the microtubular network of interphase cells, thereby leading to apoptosis. This agent appears to function as an inhibitor of tubulin assembly, while exhibiting quantitatively different behaviors and showing lower binding capacity than the classic Vinca alkaloids. Furthermore, vinflunine exhibits improved pharmacokinetic properties, including increased lipophilicity, and is more resistant to metabolic degradation. ( NCI )] (UMLS (NCI) C0672663) =Organic Chemical; Pharmacologic Substance ;
| - 1699. 4-Amino-7.beta.-D-ribofuranosyl-7H-pyrrolo(2, 3-d)pyrimidine
- [antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids; an antineoplastic antimetabolite. ( CSP )] (UMLS (NCI) C0041286) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=antifungal antibiotic;
antineoplastic antibiotics;
antitubercular agent;
ribonucleoside;
nucleoside analog;
|
- 1650. 4'-Deoxy-4'-Iododoxorubicin
- [A substance that is being studied as a treatment for cancer, and for primary systemic amyloidosis (a disease in which proteins are deposited in specific organs). It belongs to the family of drugs called anthracycline analogues. ( NCI )] (UMLS (NCI) C0047758) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 1700. 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide
- [A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfisoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death. ( NCI )] (UMLS (NCI) C0038745) =Organic Chemical; Pharmacologic Substance ;
=Sulfanilamides;
[AM650] SULFONAMIDE/RELATED ANTIMICROBIALS =SULFISOXAZOLE DIOLAMINE;
Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-;
SULFISOXAZOLE DIOLAMINE;
Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-;
SULFISOXAZOLE 500 MG;
SULFISOXAZOLE 600 MG;
SULFISOXAZOLE 10 %;
SULFISOXAZOLE 15 % |
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