- 1. (gamma)
- [The gamma-distribution used for data that is skewed and bounded to the right, i.e. where the maximum of the distribution curve is located near the origin. The g-distribution has a two parameters a and b. The relationship to mean m and variance s2 is m = a b and s2 = a b2. ( HL7V3.0 )] (UMLS (HL7) C1552644) =Intellectual Product =ProbabilityDistributionType;
| - 51. G(s) Alpha
- [G(s) alpha is a subunit of the heterotrimeric G(s) protein. G(s) alpha couples hormone-receptor binding to adenylyl cylase activity and cAMP signaling. ( NCI )] (UMLS (NCI) C0086903) =Amino Acid, Peptide, or Protein; Enzyme
|
- 2. (Glycolato-O,O')diammineplatinum(II)
- [A second-generation cisplatin analogue with antineoplastic activity. Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucelophillic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death. This agent appears to be less nephrotoxic and neurotoxic compared to both cisplatin and carboplatin. ( NCI )] (UMLS (NCI) C0093999) =Organic Chemical; Pharmacologic Substance
| - 52. G-actin
- (UMLS (NCI) C0016890) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 3. .gamma.-(p-bis(2-chloroethyl)aminophenyl)butyric acid
- [nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others; may be a carcinogen. ( CSP )] (UMLS (NCI) C0008163) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance =[AN000] ANTINEOPLASTICS;
Nitrogen Mustard Compound;
Antineoplastic Alkylating Agent;
haloalkylamine =CHLORAMBUCIL 2 MG;
| - 53. G-CSF
- [G-CSF. A colony-stimulating factor that stimulates the production of neutrophils (a type of white blood cell). It is a cytokine that belongs to the family of drugs called hematopoietic (blood-forming) agents. Also called filgrastim. ( NCI )] (UMLS (NCI) C0376562) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=Colony Stimulating Factor 3;
Colony-Stimulating Factors, Recombinant =FILGRASTIM |
- 4. 1-[5-guanidino-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]pentanoyl]-4-methyl-piperidine-2-carboxylic acid
- [A synthetic derivative of L-arginine with antithrombotic activity. Argatroban is a univalent and direct inhibitor of fibrin-bound thrombin. This agent reversibly binds to the thrombin active site thereby preventing the thrombin-dependent reactions, which include conversion of fibrinogen to fibrin; the activation of factors V, VIII and XI; the activation of protein C; and platelet aggregation. Argatroban is highly selective for thrombin and is able to inhibit the action of both free and clot-associated thrombin. As a result, stabilization of blood clots and coagulation is inhibited. ( NCI )] (UMLS (NCI) C0048470) =Organic Chemical; Pharmacologic Substance =[BL100] ANTICOAGULANTS;
Pipecolic Acids =ARGATROBAN 100 MG/ML | - 54. g/24.h
- (UMLS (NCI) C0439417) =Quantitative Concept
|
- 5. 14G2A
- [A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity. Monoclonal antibody 14G2A binds to the ganglioside GD2 and induces antibody-dependent cell mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. (NCI04) ( NCI )] (UMLS (NCI) C0280838) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 55. g/l
- [The SI derived unit of mass concentration defined as the concentration of one kilogram of a substance in unit volume of the mixture equal to one cubic meter, or the concentration of one milligram of a substance in unit volume of the mixture equal to one milliliter, or one gram of a substance per one liter of the mixture. It is also a unit of mass density (volumic mass) defined as the density of substance which mass equal to one milligram occupies the volume one milliliter. ( NCI )] (UMLS (NCI) C0439294) =Quantitative Concept
|
- 6. 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic Acid
- [A sialic acid analog and a neuraminidase inhibitor with antiviral property. Zanamivir selectively inhibits influenza A and B virus neuraminidase, a viral surface glycoprotein, which mediates the cleavages of sialic acid residues on the surfaces of host cells and influenza viral envelopes. The uncleaved sialic acid residues were bound by viral hemagglutinin, thereby resulting in viral aggregation at the host cell surface, thereby preventing the release of influenza virus particles into the respiratory tract. ( NCI )] (UMLS (NCI) C0216660) =Organic Chemical; Pharmacologic Substance ;
=[AM800] ANTIVIRALS;
Sialic Acids =ZANAMIVIR 5 MG | - 56. g/m2
- [A metric unit of areal density equal to approximately 0.029 4935 ounce per square yard. Also used as a dose calculation unit. ( NCI )] (UMLS (NCI) C1300564) Gram per Meter Squared;
Gram per Square Meter;
Gram Per Square Metre;
gsm =Quantitative Concept |
- 7. 40083
- [Encoded by human IFITM1 Gene (IFN-Induced Transmembrane Protein Family), 125-amino acid 14-kD Interferon-Induced Transmembrane Protein 1 is an IFN-alpha- and -gamma-inducible membrane protein subunit of a multimeric complex involved in antiproliferative and homotypic adhesion signal transduction. IFITM1 Protein appears to demarcate germ cells from somatic neighbors and to mark the onset of germ cell competence. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1312248) CD225 Antigen;
Fragilis Homolog;
IFI17;
IFITM1;
IFITM1 Protein;
Interferon-Induced Protein 17;
Interferon-Induced Transmembrane Protein 1;
Interferon-Inducible Protein 9-27;
Interferon-Inducible Transmembrane Protein 11;
LEU13;
LEU-13 Antigen =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 57. g/m3
- [The metric unit of mass concentration defined as the concentration of one gram of a substance in unit volume of the mixture equal to one cubic meter. The concept also refers to the metric unit of mass density (volumic mass) defined as the density of substance which mass equal to one gram occupies the volume one cubic meter. ( NCI )] (UMLS (NCI) C0439268) =Quantitative Concept
|
- 8. 40148
- [Encoded by human DEC1 Gene, widely expressed 70-amino acid DEC1 Protein is a candidate tumor suppressor protein of unknown function; possibly negative regulation of cell proliferation. (from LocusLink, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0664219) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 58. g/mL
- [A unit of mass concentration defined as the concentration of one kilogram of a substance in unit volume of the mixture equal to one liter. The concept also refers to the unit of mass density (volumic mass) defined as the density of substance which mass equal to one kilogram occupies the volume one liter. ( NCI )] (UMLS (NCI) C1300565) Gram per Milliliter;
kg/L;
Kilogram per Liter;
Kilogram Per Litre;
kilogram(s)/litre;
mg/mcl;
mg/uL;
Microgram per Nanoliter;
Milligram per Microliter;
ug/nL =Quantitative Concept |
- 9. 40148
- [This gene may play a role in tumor suppression. ( NCI )] (UMLS (NCI) C1333212) DEC1 Gene;
Deleted in Esophageal Cancer 1 Gene =Gene or Genome ;
| - 59. G0 phase
- [A quiescent state of cells during G1 PHASE. ( MSH )] (UMLS (CSP) C0079394) =Temporal Concept ;
|
- 10. G
- [Maxillary left lateral primary incisor ( HL7V3.0 )] (UMLS (HL7) C0227091) =Body Part, Organ, or Organ Component =Primary dentition;
| - 60. G1
- [Phase of the cell cycle preceding DNA synthesis (Gap 1 phase). The subphases of G1 include competence, entry (G1a), progression (G1b), and assembly (G1c), based on the effects of limiting growth factors, nutrients, or inhibitors. ( NCI )] (UMLS (NCI) C0079395) =Temporal Concept ;
|
- 11. g
- [Inertial force produced by accelerations or gravity, expressed in gravitational units; one G is equal to the pull of gravity at the earth's surface at sea level and 45 degrees North latitude (32.1725 ft/sec2; 980.621 cm/sec2). ( NCI )] (UMLS (NCI) C0086323) =Natural Phenomenon or Process
| - 61. G1
- [Describes tumor cells that generally retain the appearance of normal cells and tend to grow and spread at a slower rate than undifferentiated or poorly differentiated tumor cells. ( NCI )] (UMLS (NCI) C0205615) =Qualitative Concept
|
- 12. g
- [A metric unit of mass equal to one one thousandth of a kilogram. (NCI) ( NCI )] (UMLS (NCI) C0439208) =Quantitative Concept =UnitOfMeasureAtomBaseUnitSens;
UnitOfMeasureAtomBaseUnitInsens;
UnitOfMeasureAtomSens;
| - 62. G1
- (UMLS (NCI) C0687695) =Qualitative Concept ;
|
- 13. G Alpha Interacting Protein
- [Expressed most in lung, placenta, liver, and heart by human RGS19 Gene (RGS Family), membrane-bound fatty acylated 217-aa 25-kDa Regulator of G-protein Signaling 19 is a guanosine triphosphatase-activating protein, containing 1 RGS domain, that specifically interacts with G protein GAI3 and down-regulates G Alpha i/G Alpha q-linked signaling. Heavily palmitoylated in the Cys string motif and mainly phosphorylated on Ser residues, RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, driving them into the inactive GDP-bound form. RGS19 binds to G-Alpha subfamily 1 members and interacts with GIPC PDZ domain. (NCI) ( NCI )] (UMLS (NCI) C0384780) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 63. G12 grant
- [ ] (UMLS (CSP) C1537015) =Research Activity
|
- 14. G Antigen Family D, Protein 3
- [Expressed in testis and placenta by human GAGED3 Gene (GAGE Family, CT Family), 111-aa 12-kD XAGE3 Protein has unknown function and shares similarity with GAGE/PAGE proteins, as well as with Pyridoxal-Dependent Decarboxylase Conserved Domain (C. elegans) and Larval Locomotory Behavior Glutamate Decarboxylase (Drosophila). (NCI) ( NCI )] (UMLS (NCI) C1333657) GAGED3;
GAGED3 Protein;
XAGE-2 Protein;
XAGE3 Protein;
XAGE-3 Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 64. G15 Protein
- [Widely expressed by human RBM5 Gene, 815-aa 92-kDa RNA Binding Motif Protein 5 contains 2 RRM domains, a G-patch domain, and a RANBP2-type zinc finger and specifically binds to RNA. (NCI) ( NCI )] (UMLS (NCI) C0907884) Putative Tumor Suppressor LUCA15;
RNA Binding Motif Protein 5;
RNA-Binding Protein 5 =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 15. G Beta Gamma
- [G beta-gamma dimers associate with the alpha subunit to comprise heterotrimeric G proteins. This dimer stimulates various, and sometimes opposing, cell signaling events in response to ligation of a G protein coupled receptor, such as the beta-adrenergic, adenosine, dopamine, LTB4, and PGE2 receptors, among many others. ( NCI )] (UMLS (NCI) C1333730) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 65. G17DT
- [An immunotoxin containing an epitope of human gastrin conjugated to diphtheria toxin, with antineoplastic activity. The gastrin epitope in this vaccine is chemically identical or similar to the endogenous gastrin-17 (G-17), a 17-amino acid peptide hormone that stimulates secretion of gastric acid by the stomach. Diphtheria toxin inhibits protein synthesis via modifying translation elongation factor 2 (EF-2). Vaccination with this immunotoxin may elicit production of antibodies against gastrinoma cells overexpressing gastrin, in addition to the toxic effects on protein synthesis exerted by the diphtheria toxin moiety. ( NCI )] (UMLS (NCI) C0935889) Gastrin Immunotoxin =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 16. G Cell Neoplasm
- [A gastrin-secreting endocrine neoplasm of the non-beta islet cells. It is usually located in the pancreas but it is also found at other anatomic sites, including stomach and small intestine. ( NCI )] (UMLS (NCI) C0017150) =Neoplastic Process =Islet Cell Adenoma;
=gastrinoma syndrome | - 66. G2
- [Phase of the cell cycle following DNA synthesis and preceding mitosis (Gap 2 phase). The chromosomes are tetraploid in this phase. ( NCI )] (UMLS (NCI) C0079396) =Temporal Concept ;
|
- 17. G protein
- [family of small membrane-bound proteins which, in the presence of GTP/GDP, transduce signals from receptor to effector molecules across the membrane; do not use for other guanine nucleotide binding proteins. ( CSP )] (UMLS (CSP) C0086376) =Amino Acid, Peptide, or Protein; Enzyme ;
=guanine nucleotide binding protein;
=transducin;
exchange factor;
| - 67. G2
- [Describes tumor cells that have lost some of the appearance of normal cells. They tend to grow and spread at a faster rate than well differentiated tumor cells. ( NCI )] (UMLS (NCI) C0205616) =Qualitative Concept
|
- 18. G protein coupled receptor
- [Cell surface receptors that are coupled to G-proteins (GTP-binding protein). G-protein coupled receptors are thought to have seven membrane spanning domains and have been divided into 2 subclasses: those in which the binding site is in the extracellular domain for example receptors for glycoprotein hormones, such as thyroid stimulating hormone (TSH) and follicle-stimulating hormone (FSH) and those in which the ligand binding site is likely to be in the plane of the 7 transmembrane domains for example rhodopsin and receptors for small neurotransmitters and hormones for example muscarinic acetylcholine receptor. ( NCI )] (UMLS (CSP) C0682972) =Amino Acid, Peptide, or Protein; Receptor
| - 68. G20 grant
- [ ] (UMLS (CSP) C1537016) =Governmental or Regulatory Activity
|
- 19. G protein coupled receptor kinase
- [serine and threonine protein kinases that specifically recognize activated G protein coupled receptor proteins. ( CSP )] (UMLS (CSP) C0872043) =Amino Acid, Peptide, or Protein; Enzyme =EC 2.7.1.37;
| - 69. G207
- [A recombinant herpes simplex virus (HSV-1) mutant strain, with antineoplastic property. G207 is attenuated and is engineered to selectively replicate within cancer cells. This oncolytic HSV mutant virus has defects in genes encoding for both ribonucleotide reductase and the neurovirulence factor, ICP34.5 (gamma34.5), and is thus neuroattenuated. G207 has potent anticancer vaccination effects due to its cytotoxicity to cancer cells. Furthermore, it can be used as a gene transfer vector without compromising safety. ( NCI )] (UMLS (NCI) C1134718) =Pharmacologic Substance
|
- 20. G Protein Gene
- [Classification. Proto-oncogenes that code for G proteins. ( NCI )] (UMLS (NCI) C0812324) Proto-Oncogene, G-Protein;
=Gene or Genome ;
| - 70. G22P1
- [This gene is involved in DNA repair and DNA metabolic processes. ( NCI )] (UMLS (NCI) C1333651) G22P1 Gene;
Thyroid Autoantigen 70kDa (Ku Antigen) Gene;
=Gene or Genome ;
|
- 21. G Protein Pathway Suppressor 1 Gene
- [This gene is involved in suppression of signal transduction. ( NCI )] (UMLS (NCI) C1333702) GPS1;
GPS1 Gene =Gene or Genome | - 71. G28-5 sFv-PE40
- [An immunotoxin consisting of an anti-CD40 antibody linked to a 40kD fragment of Pseudomonas exotoxin. ( NCI )] (UMLS (NCI) C0540053) =Organic Chemical; Pharmacologic Substance; Immunologic Factor
|
- 22. G Protein Pathway Suppressor 2
- [G Protein Pathway Suppressor 2 Protein (GPS2), encoded by the GPS2 gene, are two distinct protein isoforms from specified transcript variants. In budding yeast, GPS is a suppressor of lethal G-protein subunit-activating mutations in the pheromone response pathway. In mammalian cells, GPS2 has been shown to suppress RAS- and mitogen-activated protein kinase-mediated signaling and interfere c-Jun N-terminal Kinase activation. GPS2 is also involved in transcriptional activation of papillomavirus genes through its interaction with virus E2 and E6 proteins. (from LocusLink) ( NCI )] (UMLS (NCI) C0533630) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 72. G3
- [Describes tumor cells that generally have lost most of the appearance of normal cells. They tend to grow and spread. ( NCI )] (UMLS (NCI) C0205617) =Qualitative Concept
|
- 23. G Protein Pathway Suppressor 2 Gene
- [This gene plays a role in suppression of signal transduction. ( NCI )] (UMLS (NCI) C1333703) GPS2;
GPS2 Gene =Gene or Genome | - 73. G3
- (UMLS (NCI) C0450094) =Qualitative Concept ;
|
- 24. G Protein, Beta-2 Subunit
- [Expressed in oocytes and blastocysts by human GNB2 Gene, 340-aa 37-kDa Guanine Nucleotide Binding Protein Beta 2 is a heterotrimeric G protein beta subunit with 7 WD repeats and involved in transmembrane signaling as a transducer that regulates G protein alpha subunits and integrates signals between receptors and effector proteins. The G protein beta and gamma subunits are required for GTPase activity, for GTP replacement of GDP, and for G protein/effector interaction. (NCI) ( NCI )] (UMLS (NCI) C1333885) GNB2;
Guanine Nucleotide Binding Protein Beta 2;
Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 2;
Signal-Transducing Guanine Nucleotide-Binding Regulatory Protein Beta Subunit;
Transducin Beta Chain 2;
=Amino Acid, Peptide, or Protein; Biologically Active Substance | - 74. G3Fax Image
- [This is recommended only for fax applications. ( HL7V3.0 )] (UMLS (HL7) C1554998) =Idea or Concept =ImageMediaType;
|
- 25. G Protein, Beta-3 Subunit
- [Encoded by human GNB3 Gene, 340-aa 37-kDa Guanine Nucleotide Binding Protein Beta 3 is a heterotrimeric G protein beta subunit with 7 WD repeats and involved in transmembrane signaling as a transducer that regulates G protein alpha subunits and integrates signals between receptors and effector proteins. The G protein beta and gamma subunits are required for GTPase activity, for GTP replacement of GDP, and for G protein/effector interaction. A splicing polymorphism is associated with essential hypertension and obesity. ( NCI )] (UMLS (NCI) C1122941) GNB3;
GTP-Binding Regulatory Protein Beta-3 Chain;
Guanine Nucleotide Binding Protein Beta 3;
Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 3;
Transducin Beta Chain 3 =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 75. G4
- (UMLS (NCI) C0547054) =Qualitative Concept
|
- 26. G Protein-Coupled Receptor 109B Gene
- [This gene is involved in G protein-coupled receptor signal transduction and nicotinic acid receptor activity. ( NCI )] (UMLS (NCI) C1333902) GPR109B;
GPR109B Gene =Gene or Genome ;
| - 76. G6PD
- [This gene plays a role in carbohydrate metabolism. ( NCI )] (UMLS (NCI) C1333652) G6PD Gene;
Glucose-6-Phosphate Dehydrogenase Gene;
=Gene or Genome ;
|
- 27. G Protein-Coupled Receptor 17
- [G Protein-Coupled Receptor 17, encoded by the GPR17 gene, is a putative receptor for purines coupled to G-proteins. Two alternative products are primarily expressed in brain. This Integral membrane protein belongs to family 1 of G-protein coupled receptors. (from Swiss-Prot and OMIM) ( NCI )] (UMLS (NCI) C1333731) GPR17;
P2Y-Like Receptor;
Probable P2Y Purinoceptor GPR17;
R12 =Amino Acid, Peptide, or Protein; Receptor | - 77. G6PD deficiency
- [common hereditary enzyme deficiency causing varying degrees of hemolytic anemia; can cause favism, some drug induced hemolytic anemias, and chronic nonspherocytic hemolytic anemia. ( CSP )] (UMLS (CSP) C0017920) =Disease or Syndrome =ANEMIA HEMOLITIKOA;
glycogen storage disease;
Congenital Metabolic Disorder;
enzyme deficiency |
- 28. G Protein-Coupled Receptor 17 Gene
- [This gene is involved in G protein-coupled receptor signal transduction but an exact function is not known. ( NCI )] (UMLS (NCI) C1333691) GPR17;
GPR17 Gene;
=Gene or Genome | - 78. GA
- [A country in Western Africa, bordering the Atlantic Ocean at the Equator, between Republic of the Congo and Equatorial Guinea. (NCI) ( NCI )] (UMLS (NCI) C0016910) =Geographic Area ;
◊ [A country in Western Africa, bordering the North Atlantic Ocean and Senegal. (NCI) ( NCI )] (UMLS (NCI) C0016993) Geographic Area ; ◊ [A state in the southeastern United States. Its capital is Atlanta. ( NCI )] (UMLS (NCI) C0017452) Geographic Area |
- 29. G Protein-Coupled Receptor 32
- [Encoded by human GPR32 Gene (GPCR1 Family), 356-aa 40-kDa integral membrane protein G Protein-Coupled Receptor 32 is an orphan receptor with greatest similarity to chemoattractant receptors, particularly the formylpeptide receptor (FPR1). (NCI) ( NCI )] (UMLS (NCI) C0757496) GPR32;
Probable G Protein-Coupled Receptor GPR32;
=Amino Acid, Peptide, or Protein; Receptor ;
| - 79. Ga
- [rare, metallic element; symbol Ga, atomic number 31, and atomic weight 69.72. ( CSP )] (UMLS (NCI) C0016980) =Element, Ion, or Isotope ;
=heavy metal;
=gallium chloride;
Gallium nitrate;
gallium citrate |
- 30. G Protein-Coupled Receptor 32 Gene
- [This gene is involved in G protein-coupled receptor signal transduction. ( NCI )] (UMLS (NCI) C1333693) GPR32;
GPR32 Gene =Gene or Genome | - 80. Ga67 isotope
- [ ] (UMLS (CSP) C0599272) =Element, Ion, or Isotope
|
- 31. G Protein-Coupled Receptor 39
- [Widely expressed by human GPR39 Gene (GPCR1 Family), 453-aa 51-kDa 7-transmembrane orphan G Protein-Coupled Receptor 39 exhibits high homology to the growth hormone secretagogue receptor (GHSR). (NCI) ( NCI )] (UMLS (NCI) C1333733) GPR39;
Putative G Protein-Coupled Receptor GPR39 =Amino Acid, Peptide, or Protein; Receptor | - 81. Ga68 isotope
- [ ] (UMLS (CSP) C0599273) =Element, Ion, or Isotope
|
- 32. G Protein-Coupled Receptor 39 Gene
- [This gene is involved in G protein-coupled receptor signal transduction and the regulation of growth factor release. ( NCI )] (UMLS (NCI) C1333694) GPR39;
GPR39 Gene =Gene or Genome | - 82. GAB2
- [GRB2-Associated Binding Protein 2 (GAB2), encoded by the human GAB2 gene, is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Upon tyrosine phosphorylation, GAB2 interacts with SHP2 tyrosine phosphatase and GRB2 adapter protein. It is the limiting component of the GAB2-SHP2 complex, signaling Erk MAP kinase activation and terminal differentiation of K562 CML cells. GAB2 also has an inhibitory effect on the activation of ELK1-dependent transcription triggered by a dominant active Ras mutant or under growth factor stimulation. Two alternatively spliced transcripts encode different isoforms and the short isoform is the main isoform. This protein is overexpressed and estrogen regulated in human breast cancer. (From LocusLink, OMIM and NCI) ( NCI )] (UMLS (NCI) C0387800) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 33. G Protein-Coupled Receptor 54
- [Encoded by human GPR54 Gene, 395-aa 43-kDa G Protein-Coupled Receptor 54 is a Gq/11-coupled receptor for endogenous KISS1 (Metastin), which appears to inhibit chemotaxis. (NCI) ( NCI )] (UMLS (NCI) C1097812) G Protein-Coupled Receptor AXOR12;
GPR54;
G-Protein-Coupled Receptor GPR54;
Metastin Receptor;
=Amino Acid, Peptide, or Protein; Receptor ;
| - 83. GAB2
- [This gene plays a role in signal transduction and regulates T-cell proliferation. It is also involved in bone homeostasis and mediates the differentiation of progenitor cells into osteopaths. ( NCI )] (UMLS (NCI) C1333653) GAB2 Gene;
GRB2-Associated Binding Protein 2 Gene;
=Gene or Genome ;
|
- 34. G Protein-Coupled Receptor 54 Gene
- [This gene plays a role in G protein-coupled receptor signal transduction and is associated with thyroid carcinoma. ( NCI )] (UMLS (NCI) C1333695) GPR54;
GPR54 Gene =Gene or Genome | - 84. GABA aminotransferase
- [An enzyme that converts brain gamma-aminobutyric acid (GAMMA-AMINOBUTYRIC ACID) into succinate semialdehyde, which can be converted to succinic acid and enter the citric acid cycle. It also acts on beta-alanine. EC 2.6.1.19. ( MSH )] (UMLS (CSP) C0002543) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 35. G Protein-Coupled Receptor 68
- [G Protein-Coupled Receptor 68, encoded by the GPR68 gene, belongs to family 1 of G-protein coupled receptors. This integral membrane protein is a receptor for sphingosylphosphorylcholine and couples to G proteins that stimulate phosphoinositide hydrolysis. It acts as a proton-sensing receptor stimulating inositol phosphate formation and is involved in pH homeostasis. The skeleton participates in pH homeostasis as a buffering organ and osteoblasts respond to pH changes in the physiologic range. This receptor represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. (from Swiss-Prot and OMIM) ( NCI )] (UMLS (NCI) C1259265) GPR68;
OGR-1;
Ovarian Cancer G Protein-Coupled Receptor 1;
Sphingosylphosphorylcholine Receptor;
=Amino Acid, Peptide, or Protein; Receptor ;
| - 85. GABA receptor
- [regulate a family of transmembrane chloride channels such that binding of GABA or its analogs permits increased chloride influx, membrane hyperpolarization, and inhibition of postsynaptic electrical activity. ( CSP )] (UMLS (CSP) C0206518) =Amino Acid, Peptide, or Protein; Receptor =neurotransmitter receptor;
chloride channel |
- 36. G Protein-Coupled Receptor 68 Gene
- [This gene is involved in G protein-coupled receptor signal transduction and pH homeostasis. ( NCI )] (UMLS (NCI) C1333696) GPR68;
GPR68 Gene =Gene or Genome | - 86. GAC1
- [Glioma Amplified on Chromosome 1 Protein, encoded by the human GAC1 gene, belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. GAC1 has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. (From LocusLink and NCI) ( NCI )] (UMLS (NCI) C1308623) Glioma Amplification on Chromosome 1;
Glioma Amplified on Chromosome 1 Protein;
Glioma Amplified on Chromosome 1 Protein (Leucine-Rich);
Leucine Rich Repeat Neuronal 5 Protein;
LRRN5 =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 37. G Protein-Coupled Receptor Gene
- [These genes encodes G protein-coupled receptors (GPRs or GPCRs). GPRs contain 7 hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops and transduce a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins. (from OMIM 604161) ( NCI )] (UMLS (NCI) C1367690) GPCR;
GPR =Gene or Genome | - 87. GADD45 Gene Product
- [Growth Arrest and DNA-Damage-Inducible, Alpha, encoded by the GADD45A gene, is widely expressed in normal tissues and its expression is increased by DNA damage. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. The GADD45A protein responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. This nuclear protein interacts with the proliferating cell nuclear antigen (PCNA), a component of DNA replication/repair complexes, and the cyclin dependent kinase inhibitor p21Cip1. ( NCI )] (UMLS (NCI) C1098917) GADD45A;
GADD45A Protein;
Growth Arrest and DNA Damage-Inducible Gene 45 Protein;
Growth Arrest and DNA-Damage-Inducible, Alpha =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 38. G Protein-Coupled Receptor Kinase 1 Gene
- [This gene is involved in sensory transduction necessary for vision. ( NCI )] (UMLS (NCI) C1335620) GRK1;
GRK1 Gene =Gene or Genome ;
| - 88. GADD45A
- [This gene plays a role in signal transduction and is induced in response to environmental stress. It is involved in apoptosis, DNA repair and negative regulation of cell growth. ( NCI )] (UMLS (NCI) C1333655) GADD45A Gene;
Growth Arrest and DNA-Damage-Inducible, Alpha Gene;
=Gene or Genome ;
|
- 39. G Protein-Coupled Receptor Kinase 1B
- [Encoded by human RHOK Gene (GPRK Family), 563-aa 64-kDa membrane-bound Rhodopsin Kinase, containing 1 RGS domain, regulates GPCR rhodopsin desensitization and initiates rhodopsin deactivation by phosphorylation following light stimulation. (NCI) ( NCI )] (UMLS (NCI) C1384522) GRK1;
Rhodopsin Kinase;
RHOK;
RK;
=Amino Acid, Peptide, or Protein; Enzyme | - 89. GADODIAMIDE
- (UMLS (NCI) C0082646) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
=Gadolinium DTPA;
Inactive Ingredient Preparations =GADODIAMIDE 287 MG/ML;
|
- 40. G Protein-Coupled Receptor Kinase 4 Gene
- [This gene is involved in signal transduction. ( NCI )] (UMLS (NCI) C1333698) GRK4;
GRK4 Gene =Gene or Genome | - 90. gadolinium
- [element of the rare earth family of metals, atomic symbol Gd, atomic number 64, and atomic weight 157.25; chelated gadolinium is used as a paramagnetic contrast agent in magnetic resonance imaging, and Gd153 is used in dual photon absorptiometry. ( CSP )] (UMLS (CSP) C0016911) =Pharmacologic Substance; Element, Ion, or Isotope =Metals, Rare Earth;
|
- 41. G Protein-Coupled Receptor Kinase 5 Gene
- [This gene plays a role in signal transduction and the regulation of polymorphonuclear leukocyte motility. ( NCI )] (UMLS (NCI) C1333699) GRK5;
GRK5 Gene =Gene or Genome | - 91. Gadolinium Texaphyrin
- [A substance that makes tumor cells more sensitive to radiation; it can also enhance tumor images using magnetic resonance imaging (MRI). Motexafin gadolinium belongs to the family of drugs called metalloporphyrin complexes. Also called gadolinium texaphyrin. ( NCI )] (UMLS (NCI) C0964264) Gd (III) Texaphryin;
Gd-Tex;
Motexafin Gadolinium =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid |
- 42. G Protein-Coupled Receptor Kinase 6 Gene
- [This gene is involved in signal transduction. ( NCI )] (UMLS (NCI) C1333700) GRK6;
GRK6 Gene =Gene or Genome | - 92. GADOTERIDOL
- (UMLS (NCI) C0060930) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
=Heterocyclic Compound;
Organometallic Compound;
[DX900] DIAGNOSTICS, OTHER;
=GADOTERIDOL 279.3 MG/ML;
|
- 43. G Protein-Coupled Receptor Kinase 7 Gene
- [This gene plays a role in signal transduction within the retina. ( NCI )] (UMLS (NCI) C1333701) GRK7;
GRK7 Gene =Gene or Genome | - 93. Gadoversetamide
- [A paramagnetic extracellular magnetic resonance imaging (MRI) contrast agent that facilitates visualization of abnormal vascularity. When placed in a magnetic field, gadoversetamide decreases T1 (spin-lattice or longitudinal relaxation time) and T2 (spin-spin or transverse relaxation time) values in tissues where it accumulates. At the recommended dose, the effect is primarily on T1 relaxation time, and produces an increase in signal intensity. Gadoversetamide does not cross the intact blood-brain barrier. However, abnormal vascularity or disruption of the blood-brain barrier allows accumulation of gadoversetamide. (NCI05) ( NCI )] (UMLS (NCI) C0754820) GADOVERSETAMIDE PREPARATION =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
=Optimark;
[DX201] IMAGING AGENTS (IN VIVO) RADIOPHARMACEUTICALS =GADOVERSETAMIDE 330.9 MG/ML;
|
- 44. G Protein-Coupled Receptor Kinase Gene
- [G Protein-Coupled Receptor Kinase Genes encode G Protein-Coupled Receptor Kinases, which regulate through phosphorylation the signaling function of G protein-coupled receptors and signal transduction. (NCI) ( NCI )] (UMLS (NCI) C1333739) =Gene or Genome ;
| - 94. GAG
- [DNA sequences that form the coding region for proteins associated with the viral core in retroviruses. gag is short for group-specific antigen. ( MSH )] (UMLS (NCI) C0017346) =Gene or Genome
|
- 45. G Protein-Coupled Receptor Kinase Interactor 1 Gene
- [This gene plays a role in signal transduction and cytoskeletal remodeling. ( NCI )] (UMLS (NCI) C1333676) GIT1;
GIT1 Gene =Gene or Genome ;
| - 95. gag gene related protein
- [ ] (UMLS (CSP) C0751607) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 46. G Protein-Coupled Receptor Kinase Interactor 2 Gene
- [This gene is involved in signal transduction and regulation of receptor signaling. ( NCI )] (UMLS (NCI) C1333677) GIT2;
GIT2 Gene;
=Gene or Genome ;
| - 96. GAG Protein
- [retroviral protein encoded by the gag gene; gag refers to group- specific antigen. ( CSP )] (UMLS (NCI) C0017279) =Amino Acid, Peptide, or Protein; Biologically Active Substance =Viral Protein;
|
- 47. G Protein-Coupled Receptor Kinase-Interactor 1
- [G Protein-Coupled Receptor Kinase-Interactor 1: GIT1 is a multidomain protein that is thought to function as an integrator of signaling pathways controlling vesicle trafficking, adhesion and cytoskeletal organization. (from J Cell Sci 2002 Apr 1;115(Pt 7):1497-510) ( NCI )] (UMLS (NCI) C1333736) GIT1;
=Amino Acid, Peptide, or Protein; Biologically Active Substance | - 97. gag(glycosaminoglycan)
- [polymers of alternating sugar acids and aminosugars, which may be sulfated or otherwise further substituted; contribute to adhesion, elasticity, viscosity, etc., of extracellular substances. ( CSP )] (UMLS (CSP) C0017973) =Carbohydrate; Biologically Active Substance ;
=glycan;
=chondroitin;
HYALURONATE;
sulfomucopolysaccharide;
chondroitin;
heparin;
heparan sulfate;
Hyaluronic Acid |
- 48. G Protein-Coupled Receptor, Family C, Group 5, Member C
- [Expressed in stomach, kidney, liver, lung, pancreas, central nervous system, and prostate by human GPRC5C Gene (GPCRc Family), 441-aa 48-kDa 7-transmembrane G Protein-Coupled Receptor Family C Group 5 Member C has an extracellular N-terminal domain, an intracellular C-terminal domain, and conserved cysteines residues. The specific protein function is unknown; it may mediate retinoic acid effects on G protein signal transduction. (NCI) ( NCI )] (UMLS (NCI) C0963060) GPRC5C;
Orphan G-Protein Coupled Receptor;
Retinoic Acid Responsive Gene Protein;
=Amino Acid, Peptide, or Protein; Receptor ;
| - 98. gagging
- [Clinical manifestation of the digestive system consisting of contraction of the muscle of the pharynx caused by stimulation of sensory receptors on the soft palate, by psychic stimuli, or systemically by drugs. ( MSH )] (UMLS (CSP) C0016927) =Finding ;
=gastrointestinal sign/symptom;
|
- 49. G Protein-Coupled Receptor, Family C, Group 5, Member C Gene
- [This gene plays a role in G protein-coupled receptor signal transduction but the specific function of this protein is unknown. ( NCI )] (UMLS (NCI) C1333697) GPRC5C;
GPRC5C Gene =Gene or Genome | - 99. gait
- [manner of running, walking, or moving on foot; applicable to humans or animals. ( CSP )] (UMLS (CSP) C0016928) =Finding ;
=chordate locomotion;
|
- 50. G(q) Alpha
- [the alpha subunit of the G(q) class of heterotrimeric G proteins. ( NCI )] (UMLS (NCI) C1333650) =Amino Acid, Peptide, or Protein; Enzyme
| - 100. GAL-8
- [Constitutively and ubiquitously expressed by human LGALS8 Gene (S-Lectin Family), 316-amino acid 35.5-kD extracellular Galectin 8 contains two carbohydrate-binding (recognition) domains (CRDs) and binds to beta galactoside in cell adhesion, cell cycle regulation, inflammation, immunomodulation, apoptosis, and metastasis. Galectin 8 may be involved in activation of various cell types through cross-linkage of cell surface glycoproteins and may be involved in some types of cancer. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1098710) Galectin 8;
Lectin, Galactoside-Binding, Soluble, 8;
LGALS8;
LGALS8 Protein;
PCTA1;
Po66 Carbohydrate Binding Protein;
PO66 Carbohydrate-Binding Protein;
PO66-CBP;
Prostate Carcinoma Tumor Antigen;
Prostate Carcinoma Tumor Antigen 1 =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
home
