6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) Monoacetate

[The acetate salt of a synthetic nonapeptide analogue of gonadotropin-releasing hormone. Leuprolide binds to and activates gonadotropin-releasing hormone (GnRH) receptors. Continuous, prolonged administration of leuprolide in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. This agent reduces testosterone production to castration levels and may inhibit androgen receptor-positive tumor progression. ( NCI )]

UMLS (NCI) C0700596

Amino Acid, Peptide, or Protein
Pharmacologic Substance
Hormone

Relation/PAR: 6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig)

Relation/CHD: LEUPROLIDE ACETATE 11.25 MG
LEUPROLIDE ACETATE 15 MG
LEUPROLIDE ACETATE 22.5 MG
LEUPROLIDE ACETATE 30 MG
LEUPROLIDE ACETATE 65 MG
LEUPROLIDE ACETATE 72 MG
LEUPROLIDE ACETATE 7.5 MG
LEUPROLIDE ACETATE 1 MG/0.2ML
LEUPROLIDE ACETATE 3.75 MG

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