- 1. ((o-Carboxyphenyl)thio)ethylmercury, Sodium Salt
- [An organomercurial compound and derivative of thiosalicyclic acid with antibacterial and antifungal properties. Although the mechanism of action has not been fully elucidated, thimerosal inhibits sulfhydryl-containing active site of various enzymes and binds to sulfhydryl compounds, such as glutathione, cysteine, and SH groups of proteins. In addition, thimerosal activates the InsP3 calcium channel on endoplasmic reticular membrane, thereby triggering the release of calcium from intracellular stores resulting in a calcium-induced calcium-influx of extracellular calcium. Consequently, thimerosal may induce or inhibit cellular functions dependent on calcium signaling. ( NCI )] (UMLS (NCI) C0039867) =Organic Chemical; Pharmacologic Substance ;
=Ethylmercury Compounds; [DE101] ANTIBACTERIAL, TOPICAL; Inactive Ingredient Preparations; =xylometazoline 1 MG/ML Nasal Solution; BORIC ACID/NA BORATE SOLN IRRG,OPH; DESOXYRIBONUCLEASE 15000 UNT / FIBRINOLYSIN 25 UNT IRRIGATION SOLUTION; HEMOPHILUS B CONJUGATE VACCINE INJ; HEPATITIS B IMMUNE GLOBULIN (IM) INJ; INFLUENZA VIRUS VACCINE (SPLIT VIRUS),SYRINGE,0.5ML; INFLUENZA VIRUS VACCINE (SPLIT VIRUS),VIL,5ML; Polyvinyl Alcohol 0.3 ML/ML Ophthalmic Solution; Rabies Immune Globulin (Human) Inj 150 IU/ML; TETANUS IMMUNE GLOBULIN,HUMAN 250UNT/ML INJ,SYRINGE,1ML; THIMEROSAL SWAB, MEDICATED; INFLUENZA SUBVIRON VACCINE,VIL,5ML; INFLUENZA SUBVIRON VACCINE,SYRINGE,0.5ML; THIMEROSAL 0.001 %; THIMEROSAL 0.002 %; THIMEROSAL 0.005 %; THIMEROSAL 0.01 %; THIMEROSAL 0.07 %; THIMEROSAL 1:1000; THIMEROSAL 0.1 %; THIMEROSAL 0.004 % | - 51. O-ethyl-S-[2(diethylamino)ethyl]methylphosphonothioate
- [ ] (UMLS (CSP) C1113676) =Organic Chemical; Hazardous or Poisonous Substance
|
- 2. (o,p)-DDD
- [An anticancer drug used in treating adrenocortical cancer and ACTH-producing pituitary tumors (Cushing's disease). ( NCI )] (UMLS (NCI) C0026256) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS; chlorohydrocarbon =MITOTANE 500 MG | - 52. O-ethyl-S-[2(diisopropylamino)ethyl]methylphosphonothioate
- [ ] (UMLS (CSP) C1113677) =Organic Chemical; Hazardous or Poisonous Substance
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- 3. (o-Bromobenzyl)ethyldimethylammonium p-Toluenesulfonate
- [The tosylate salt form of bretylium, a quaternary ammonium salt and non-selective adrenergic neuronal blocking agent with anti-arrhythmic properties. Bretylium tosylate is selectively taken up into peripheral nerve terminals and initially causes a release of norepinephrine from sympathetic nerve endings, thereby causing a sympathomimetic effect. This is followed by a prolonged anti-adrenergic action which prevents further discharge of neurotransmitter from sympathetic nerve endings. Its myocardial effects include a prolongation of action potential as well as refractory period. This drug is used to treat and suppress ventricular arrhythmias, particularly ventricular fibrillation and ventricular tachycardia. ( NCI )] (UMLS (NCI) C0006168) =Organic Chemical; Pharmacologic Substance ;
=Bretylium Compounds; bretylium =BRETYLIUM TOSYLATE 2 MG/ML; BRETYLIUM TOSYLATE 4 MG/ML; BRETYLIUM TOSYLATE 100 MG/ML; BRETYLIUM TOSYLATE 50 MG/ML; | - 53. o-Phosphoric Acid
- [A colorless, odorless phosphorus-containing inorganic acid. Phosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++. Phosphoric acid is used in dentistry and orthodontics as an etching solution, to clean and roughen the surfaces of teeth where dental appliances or fillings will be placed. In addition, phosphoric acid is a constituent in bone and teeth, and plays a role in many metabolic processes. ( NCI )] (UMLS (NCI) C0031700) =Pharmacologic Substance; Inorganic Chemical ;
|
- 4. (OC-6-33)-dichlorodihydroxybis(2-propanamine)platinum
- [A synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and forms DNA crosslinks and platinum-DNA adducts, resulting in DNA replication failure and cell death. Although less prone to glutathione inactivation compared to cisplatin, resistance to this agent has been observed in vitro due to repair of platination damage by tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0057856) =Organic Chemical; Pharmacologic Substance ;
| - 54. O01
- (UMLS (HL7) C1549883) =Intellectual Product =Message structure;
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- 5. (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum
- [An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in cell growth inhibition and apoptosis. ( NCI )] (UMLS (NCI) C1142934) (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinum;
platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43); Satraplatin; =Organic Chemical; Pharmacologic Substance | - 55. O02
- (UMLS (HL7) C1549902) =Intellectual Product =Message structure;
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- 6. *Osmolality
- (UMLS (HL7) C1547034) =Quantitative Concept =Kind of quantity;
| - 56. O03
- (UMLS (HL7) C1549816) =Intellectual Product =Message structure;
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- 7. .omega.-Diethylamino-2,6-dimethylacetanilide
- [drug having anesthetic, sedative, analgesic, anticonvulsant and cardiac depressant activities, used as a local anesthetic; applied topically to the skin and mucous membranes. ( CSP )] (UMLS (NCI) C0023660) =Organic Chemical; Pharmacologic Substance =Acetanilides;
local anesthetic; phenylamide; [DE700] LOCAL ANESTHETICS, TOPICAL; [NT300] ANESTHETICS, MUCOSAL; =2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide Monohydrochloride; LIDOCAINE MISC. POWDER (GM); Lidocaine 0.04 MG/MG; LIDOCAINE 3 %; LIDOCAINE 5 MG; LIDOCAINE 1 %; LIDOCAINE 4 %; LIDOCAINE 5 %; LIDOCAINE 10 %; LIDOCAINE 0.4 %; LIDOCAINE 2.5 % | - 57. O04
- (UMLS (HL7) C1549826) =Intellectual Product =Message structure;
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- 8. 1 or More Positive Axillary Nodes
- [Presence of one or more lymph nodes in the area of the armpit in which cancerous cells have been detected. ( NCI )] (UMLS (NCI) C0279784) =Finding
| - 58. O05
- (UMLS (HL7) C1549824) =Intellectual Product =Message structure;
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- 9. 1,1'-Oxybisethane
- [An organic compound in which two carbon atoms are linked through an oxygen atom (C-O-C). An ether may be a product of the condensation of alcohols. Ether also refers loosely to diethyl-ether, a colorless, volatile, highly inflammable liquid used in industry and biomedical research, and historically important as an anesthetic agent. In vivo, ether acts similarly to alcohol and chloroform, but its stimulant action on the heart is much more marked. Ether is a rapidly diffusible stimulant. (NCI04) ( NCI )] (UMLS (NCI) C0014994) =Organic Chemical; Pharmacologic Substance ;
=1,1'-Oxybisethane; Ethyl Ethers; Organic Chemical; [CN201] ANESTHETICS INHALATION =Ethers, Cyclic; Ethyl Ethers; Methyl Ethers; Phenyl Ethers; 1,1'-Oxybisethane; ETHER 57 %; ETHER 65 %; ETHER 69 % | - 59. O06
- (UMLS (HL7) C1549837) =Intellectual Product =Message structure;
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- 10. 1,12 (OH) D3
- [ ] (UMLS (CSP) C0750730) 1,12(OH)D3 =Inorganic Chemical ;
| - 60. O08
- (UMLS (HL7) C1549834) =Intellectual Product =Message structure;
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- 11. 1,2-Oxathiolane 2,2-Dioxide
- [A synthetic, colorless liquid or white crystalline solid that is readily soluble in water and many organic solvents such as ketones, esters and aromatic hydrocarbons. 1,3-propanesultone is used as a chemical intermediate in the production of detergents, dyes, lathering agents, bacteriostats, fungicides, insecticides, cation-exchange resins, corrosion inhibitors and vulcanization accelerators. When heated to decomposition, it emits toxic fumes of sulfur oxides. Humans are potentially exposed to residues of 1,3-propane sultone when using products manufactured from this compound. The primary routes of potential human exposure to 1,3-propane sultone are ingestion and inhalation. Contact with this chemical can cause mild irritation of the eyes and skin. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0043970) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 61. O09
- (UMLS (HL7) C1549823) =Intellectual Product =Message structure;
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- 12. 1,25 (OH) vitamin D
- [ ] (UMLS (CSP) C0370232) =Organic Chemical; Vitamin
| - 62. O10
- (UMLS (HL7) C1549835) =Intellectual Product =Message structure;
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- 13. 1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose
- [antimetabolite used in the treatment of pancreatic, lung, and other cancers. ( CSP )] (UMLS (NCI) C0045093) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=antimetabolite; [AN000] ANTINEOPLASTICS; deoxycytidine; =1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose, hydrochloride | - 63. O11, O25
- (UMLS (HL7) C1549884) =Intellectual Product =Message structure;
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- 14. 1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose, hydrochloride
- [The hydrochloride salt of an antimetabolite analog of the nucleoside pyrimidine with antineoplastic activity. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. ( NCI )] (UMLS (NCI) C0771488) 2'Deoxy-2',2'-Difluorocytidine, Hydrochloride;
Difluorodeoxycytidine Hydrochloride; Gemcitabine Hydrochloride; GEMCITABINE HYDROCHLORIDE PREPARATION =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ; =1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose; =GEMCITABINE HYDROCHLORIDE 1 GM; GEMCITABINE HYDROCHLORIDE 200 MG | - 64. O12, O26
- (UMLS (HL7) C1549905) =Intellectual Product =Message structure;
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- 15. 1-0-Octadecyl-2-O-methyl-Sn-3-glycero-phosphocholine Liposome
- [A liposomal formulation of the ether lipid 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine with potential antineoplastic activity. TLC ELL-12 induces tumor cell apoptosis via mitochondria- and caspase-mediated mechanisms. Liposomal encapsulation reduces the free agent's hemolytic toxicity. (NCI04) ( NCI )] (UMLS (NCI) C1313443) ELL-12;
TLC ELL-12 =Organic Chemical; Pharmacologic Substance ; | - 65. O13
- (UMLS (HL7) C1549886) =Intellectual Product =Message structure;
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- 16. 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine
- [produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells; several molecular species of platelet activating factor have been identified which vary in the length of the O-alkyl side chain; an important mediator of bronchoconstriction. ( CSP )] (UMLS (NCI) C0032172) =Lipid; Immunologic Factor =Blood Coagulation Factor;
| - 66. O14
- (UMLS (HL7) C1549904) =Intellectual Product =Message structure;
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- 17. 1-Octadecyl-2-methoxy-rac-glycero-3-phosphocholine
- [A synthetic analog of lysophosphatidylcholine, an ether lipid, possessing anti-leishmanial and antineoplastic activity. The mechanism of action for edelfosine has not been fully elucidated. Targeting cellular membranes, edelfosine modulates membrane permeability, membrane lipid composition, and phospholipid metabolism. Edelfosine also inhibits the phosphatidylinositol 3 kinase (PI3K)-AKT/PKB survival pathway, possibly activating the pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. In addition, this agent inhibits protein kinase C, intracellular activation of the Fas/CD95 receptor, and intracellular acidification. Anti-leishmanial activity may be due to inhibition of a glycosomal alkyl-specific-acylCoA acyltransferase. (NCI) ( NCI )] (UMLS (NCI) C0044549) =Lipid; Pharmacologic Substance ;
| - 67. O15
- (UMLS (HL7) C1549891) =Intellectual Product =Message structure;
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- 18. 10-O-Elsaminosylelsarosylchartarin
- [An heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits topoisomerase I and II, resulting in single-strand breaks and inhibition of DNA replication. (NCI04) ( NCI )] (UMLS (NCI) C0059041) =Organic Chemical; Antibiotic ;
| - 68. O15 isotope
- [ ] (UMLS (CSP) C0599274) =Element, Ion, or Isotope
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- 19. 12-O-tetradecanoylphorbol-13-acetate
- [A drug that is being studied as a treatment for hematologic cancer. ( NCI )] (UMLS (NCI) C0039654) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 69. O16
- (UMLS (HL7) C1549906) =Intellectual Product =Message structure;
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- 20. 2,4-Oxazolidinedione, 3,5,5-trimethyl-
- [A dione-type anticonvulsant with antiepileptic activity. Trimethadione reduces T-type calcium currents in thalamic neurons, thereby stabilizing neuronal membranes, raising the threshold for repetitive activities in the thalamus and inhibiting corticothalamic transmission. This decreases the abnormal thalamocortical rhythmicity, which is thought to underlie the paroxysmal three-cycle-per-second spike-and-wave pattern seen with absence (petit mal) seizures. ( NCI )] (UMLS (NCI) C0041038) =Organic Chemical; Pharmacologic Substance ;
=[CN400] ANTICONVULSANTS; oxazole =TRIMETHADIONE 150 MG; TRIMETHADIONE 300 MG; TRIMETHADIONE 40 MG/ML | - 70. O17
- (UMLS (HL7) C1549880) =Intellectual Product =Message structure;
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- 21. 2-Oxazolidinone, 4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)methyl)-,(S)-
- [A member of the triptan class agents with anti-migraine property. Zolmitriptan selectively binds to and activates serotonin (5-HT) 1B expressed in intracranial arteries and 5_HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. Receptor binding results in constriction of cranial vessels, reduction of the vessel pulsation and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Zolmitriptan may also relief migraine headaches by inhibition pro-inflammatory neuropeptide release. ( NCI )] (UMLS (NCI) C0528166) =Organic Chemical; Pharmacologic Substance ;
=[CN105] ANTIMIGRAINE AGENTS; Oxazolidinones =ZOLMITRIPTAN 2.5 MG; ZOLMITRIPTAN 5 MG; | - 71. O17 isotope
- [ ] (UMLS (CSP) C0599062) =Element, Ion, or Isotope
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- 22. 2-Oxazolidinone, 5-((3,5-dimethylphenoxy)methyl)-
- [An oxazolidinone with centrally-acting skeletal muscle relaxant properties. Although the exact mechanism through which metaxalone exerts its effect is largely unknown, it might be due to general central nervous system (CNS) depression. Metaxalone has no direct effect on the contractile mechanisms of striated muscle, the motor end plate, or the nerve fiber. ( NCI )] (UMLS (NCI) C0163055) =Organic Chemical; Pharmacologic Substance ;
=[MS200] SKELETAL MUSCLE RELAXANTS; Oxazolidinones =METAXALONE 400 MG; METAXALONE 800 MG; | - 72. O18
- (UMLS (HL7) C1549903) =Intellectual Product =Message structure;
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- 23. 2-Oxetanone
- [A colorless, highly reactive, liquid, cyclic ether with a slightly sweet odor. Beta-propiolactone was used once mainly in the manufacture of acrylic acid and esters. It also was used as a sterilant for medical materials and procedures. However, it is no longer used for medical disinfection. Dermal exposure to beta-propiolactone causes the burning or blistering of the skin, and ingestion of this substance burns the mouth and stomach while exposure to its vapors causes severe irritation of the eyes, throat and respiratory tract. This substance is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0033472) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 73. O18 isotope
- [ ] (UMLS (CSP) C0599063) =Biologically Active Substance; Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope
|
- 24. 2-oxo-N,3-bis-(2-chloroethyl) tetrahydro-2H-1,3,2-oxazaphosphorin- 2-amine
- [2-oxo-N,3-bis-(2-chloroethyl) tetrahydro-2H-1,3,2-oxazaphosphorin- 2-amine; cyclophosphamide analog with two alkylating groups, used as a DNA strand crosslinker and antineoplastic. ( CSP )] (UMLS (NCI) C0020823) =Organophosphorus Compound; Pharmacologic Substance ;
=Alkylating Activity; [AN000] ANTINEOPLASTICS; (-)-Cyclophosphamide; phosphamide; oxazine; Antineoplastic Alkylating Agent =IFOSFAMIDE 1 GM/VIL; IFOSFAMIDE 3 GM; IFOSFAMIDE 1 GM; | - 74. O19
- (UMLS (HL7) C1549817) =Intellectual Product =Message structure;
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- 25. 22-Oxovincaleukoblastine
- [inhibits microtubule formation in the mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. ( CSP )] (UMLS (NCI) C0042679) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS; vinca alkaloid =Leurocristine Sulfate | - 75. O20
- (UMLS (HL7) C1549828) =Intellectual Product =Message structure;
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- 26. 3-(o-Methoxyphenoxy)-1,2-propanediol
- [A glyceryl guaiacolate with expectorant effects. Guaifenesin increases respiratory tract mucus secretions, acts as an irritant to gastric vagal receptors and recruits efferent parasympathetic reflexes that cause glandular exocytosis. This agent reduces the viscosity of mucus secretion by reducing adhesiveness and surface tension as well as increasing hydration of mucus. Guaifenesin promotes the efficiency of the mucociliary mechanism important in removing accumulated secretions from the upper and lower airway. ( NCI )] (UMLS (NCI) C0018305) =Organic Chemical; Pharmacologic Substance =Guaiacol;
[RE400] MUCOLYTICS; [RE302] NON-OPIOID-CONTAINING ANTITUSSIVES/EXPECTORANTS; =METHOCARBAMOL; Guaifenesin 10 MG/ML; GUAIFENESIN 1200 MG; Guaifenesin 13.4 MG/ML; Guaifenesin 17 MG/ML; GUAIFENESIN 100 MG/5ML; GUAIFENESIN 250 MG; GUAIFENESIN 150 MG/5ML; GUAIFENESIN 200 MG/5ML; GUAIFENESIN 400 MG; GUAIFENESIN 25 MG/5ML; GUAIFENESIN 50 MG; GUAIFENESIN 250 MG/5ML; GUAIFENESIN 500 MG; GUAIFENESIN 600 MG; GUAIFENESIN 125 MG; Guaifenesin 15 MG/ML; GUAIFENESIN 200 MG; GUAIFENESIN 300 MG; Guaifenesin 6 MG/ML; GUAIFENESIN 100 MG; GUAIFENESIN 800 MG; GUAIFENESIN 100 MG/15ML; GUAIFENESIN 575 MG; Guaifenesin 13.3 MG/ML; GUAIFENESIN 150 MG; GUAIFENESIN 75 MG | - 76. O21
- (UMLS (HL7) C1549819) =Intellectual Product =Message structure;
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- 27. 3-o-Chlorophenyl-5-methyl-4-isoxazolylpenicillin Sodium
- [The sodium salt form of cloxacillin, a semi-synthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity. Cloxacillin is bactericidal and binds to specific penicillin-binding proteins on the bacterium and inhibits the transpeptidation enzyme, thereby preventing the cross-linking of peptidoglycans. This leads to an interruption of the bacterial cell wall and causes bacterial lysis. Cloxacillin is active against beta-lactamase producing staphylococci. ( NCI )] (UMLS (NCI) C0037496) =Organic Chemical; Antibiotic ;
=CLOXACILLIN; =CLOXACILLIN SODIUM 250 MG; CLOXACILLIN SODIUM 500 MG | - 77. O23
- (UMLS (HL7) C1549818) =Intellectual Product =Message structure;
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- 28. 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2
- [catalyzes the reduction of testosterone to 5 alphadihydrotestosterone. ( CSP )] (UMLS (NCI) C0039602) =Amino Acid, Peptide, or Protein; Enzyme ;
=hydrocarbon oxidoreductase; | - 78. O24
- (UMLS (HL7) C1549829) =Intellectual Product =Message structure;
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- 29. 3-oxobutyrate
- [ ] (UMLS (CSP) C1536988) =Organic Chemical
| - 79. O27
- (UMLS (HL7) C1549815) =Intellectual Product =Message structure;
|
- 30. 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
- [A flavonol glycoside found in many plants, including BUCKWHEAT; TOBACCO; FORSYTHIA; HYDRANGEA; VIOLA, etc. It has been used therapeutically to decrease capillary fragility. ( MSH )] (UMLS (NCI) C0035976) =Organic Chemical; Pharmacologic Substance ;
=Bioflavonoid; Inactive Ingredient Preparations =RUTIN 50 MG | - 80. O28
- (UMLS (HL7) C1549825) =Intellectual Product =Message structure;
|
- 31. 37 or more completed weeks of gestation
- [ ] (UMLS (ICD9CM) C1135248) 37+ COMP WKS GESTATION;
=Temporal Concept | - 81. O29
- (UMLS (HL7) C1548704) =Intellectual Product =Message structure;
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- 32. 4-o-Tolylazo-o-Toluidine
- [A synthetic organic azo dye used mainly in experimental research, carcinogenic o-Aminoazotoluene induces hepatomas, lung tumors, bladder tumors, and lung hemangioendotheliomas in animals when administered in the diet. (NCI04) ( NCI )] (UMLS (NCI) C0028746) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 82. O30
- (UMLS (HL7) C1548705) =Intellectual Product =Message structure;
|
- 33. 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, Monopotassium Salt,(2R-(2alpha,3Z,5alpha))-
- [A semi-synthetic beta-lactamase inhibitor isolated from streptomyces. Clavunalate potassium contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site. This protects other beta-lactam antibiotics from beta-lactamase catalysis. This drug is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms. ( NCI )] (UMLS (NCI) C0137997) =Organic Chemical; Antibiotic =CLAVULANATE;
=CLAVULANATE POTASSIUM 100 MG/100ML; CLAVULANATE POTASSIUM 62.5 MG/5ML; CLAVULANATE POTASSIUM 62.5 MG; CLAVULANATE POTASSIUM 57 MG/5ML; CLAVULANATE POTASSIUM 28.5 MG; CLAVULANATE POTASSIUM 28.5 MG/5ML; CLAVULANATE POTASSIUM 31.25 MG/5ML; CLAVULANATE POTASSIUM 125 MG; CLAVULANATE POTASSIUM 57 MG; CLAVULANATE POTASSIUM 0.1 GM/VIL; CLAVULANATE POTASSIUM 42.9 MG/5ML; CLAVULANATE POTASSIUM 31.25 MG; | - 83. O31
- (UMLS (HL7) C1548707) =Intellectual Product =Message structure;
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- 34. 5-(o-Chlorobenzyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridinium Chloride
- [The hydrochloride salt form of ticlopidine, a thienopyridine derivative with anticoagulant property. Ticlopidine hydrochloride irreversibly inhibits adenosine-diphosphate (ADP)-induced platelet-fibrinogen binding by binding to the glycoprotein (GP) IIb/IIIA complex, one of the two purinergic receptors activated by ADP. Inhibition of the receptor activation causes the inhibition of adenylyl cyclase, results in decreased levels of cyclic adenosine monophosphate and thereby interferes with platelet membrane function and subsequent, platelet-platelet interaction, release of platelet granule constituents and prolongation of bleeding time. ( NCI )] (UMLS (NCI) C0000598) =Organic Chemical; Pharmacologic Substance
| - 84. O32
- (UMLS (HL7) C1548706) =Intellectual Product =Message structure;
|
- 35. 6-O-Methylerythromycin
- [semi-synthetic macrolide antibiotic; derivative of erythromycin. ( CSP )] (UMLS (NCI) C0055856) =Organic Chemical; Antibiotic ;
=macrolide antibiotic; ERYTHROMYCIN; [AM200] ERYTHROMYCINS/MACROLIDES; [GA303] H.PYLORI AGENTS =CLARITHROMYCIN 125 MG/5ML; CLARITHROMYCIN 250 MG; CLARITHROMYCIN 500 MG; CLARITHROMYCIN 250 MG/5ML; CLARITHROMYCIN 187.5 MG/5ML; CLARITHROMYCIN 28 X 500 MG; | - 85. O33
- (UMLS (HL7) C1549820) =Intellectual Product =Message structure;
|
- 36. 6-[O-(1,1-Dimethylethyl)-D-serine]-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) 2-(aminocarbonyl)hydrazide
- [A drug that belongs to the family of drugs called gonadotropin-releasing hormone analogues. Goserelin is used to block hormone production in the ovaries or testicles. ( NCI )] (UMLS (NCI) C0120107) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=D-His-6-Pro-8-NEt-LHRH; [AN500] ANTINEOPLASTIC HORMONES =D-Ser(bu(t))(6)azgly(10)-LHRH Acetate; | - 86. O34
- (UMLS (HL7) C1549831) =Intellectual Product =Message structure;
|
- 37. 6-[O-(1,1-Dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig)
- [An anticancer drug that belongs to the family of drugs called gonadotropin-releasing hormones. In prostate cancer therapy, buserelin blocks the production of testosterone in the testicles. ( NCI )] (UMLS (NCI) C0006456) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
| - 87. O35
- (UMLS (HL7) C1549821) =Intellectual Product =Message structure;
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- 38. 7-O-[(Methylthio)methyl]paclitaxel
- [An anticancer drug that belongs to the family of drugs called mitotic inhibitors. ( NCI )] (UMLS (NCI) C0796479) beta-(Benzoylamino)-a-hydroxybenzenepropanoic Acid (aR,bS)-(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-4-[(methylthio)methoxy]-5-oxo-7,11-methano-1H;
beta-(Benzoylamino)-alpha-hydroxybenzenepropanoic Acid (aR,bS)-(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-4-[(methylthio)methoxy]-5-oxo-7,11-methano-1H; BMS-184476 =Organic Chemical; Pharmacologic Substance ; | - 88. O36
- (UMLS (HL7) C1549832) =Intellectual Product =Message structure;
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- 39. 8-Oxo-2'-Deoxyguanosine
- [A type of altered DNA base caused by oxidative DNA damage. ( NCI )] (UMLS (NCI) C0081381) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance
| - 89. O6-Benzylguanine/Polifeprosan 20 With Carmustine Implant
- (UMLS (NCI) C0879441) =Therapeutic or Preventive Procedure ;
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- 40. 8-Oxoguanine DNA Glycosylase
- [The protein 8-Oxoguanine DNA Glycosylase, encoded by the OGG1 gene, is an enzyme in base excision repair. OGG1 incises DNA at 8-oxoguanine residues and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-n-methylformamidopyrimidine (FAPY) from damaged DNA. OGG1 also has activities of beta-lyase that nicks DNA 3-prime to the lesion and endonuclease that cleaves DNA near apurinic or apyrimidinic sites to products with 5-prime-phosphate. Alternative splicing of the C-terminal region of the OGG1 gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common (1a/alpha, 1b, 1c, 2a/beta, 2b, 2c, 2d and 2e) and 1a is the prevalent form. OGG1 is ubiquitous and located in nucleus (isoform 1a) and mitochondria (isoform 2a). Defects in OGG1 are associated with tumor formation. ( NCI )] (UMLS (NCI) C1363852) N-Glycosylase/DNA Lyase;
OGG1 =Amino Acid, Peptide, or Protein; Enzyme | - 90. O6-benzylguanine/Temozolomide
- (UMLS (NCI) C0879518) =Therapeutic or Preventive Procedure ;
|
- 41. 8-Oxoguanine DNA Glycosylase Gene
- [This gene is involved in base excision repair of oxidatively damaged DNA. ( NCI )] (UMLS (NCI) C1335081) OGG1;
OGG1 Gene; =Gene or Genome ; | - 91. OAF
- [lymphokine that stimulates bone resorption; a small protein unrelated to parathyroid hormone. ( CSP )] (UMLS (CSP) C0069673) =Amino Acid, Peptide, or Protein; Immunologic Factor =lymphokine;
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- 42. O
- [Mandibular left central primary incisor ( HL7V3.0 )] (UMLS (HL7) C0227100) =Body Part, Organ, or Organ Component =Primary dentition;
| - 92. Oat Cell
- (UMLS (NCI) C1265905) =Cell
|
- 43. O
- [use this term only for elemental or gaseous oxygen (02); for other compounds see OXYGEN COMPOUND. ( CSP )] (UMLS (NCI) C0030054) =Pharmacologic Substance; Element, Ion, or Isotope =Element;
Gas; Chalcogens; oxygen compound; [RE600] NON-ANESTHETIC GASES; =OXYGEN 99.9 %; OXYGEN 100 %; OXYGEN 99 %; OXYGEN 99.5 %; OXYGEN 99.6 %; OXYGEN 21 %; OXYGEN 59.2 %; OXYGEN 98.5 %; OXYGEN 90 %VV; OXYGEN 98 %VV; OXYGEN 97 %VV; OXYGEN 95 %VV; OXYGEN 21 %VV; OXYGEN 80 %VV | - 93. Oat Cell Cancer
- [A neuroendocrine carcinoma composed of small malignant cells which are often said to resemble "oat cells" under the microscope. Small cell carcinoma most often affects the lungs. Clinically, this is often a rapidly growing cancer that spreads to distant sites early. ( NCI )] (UMLS (NCI) C0262584) =Neoplastic Process
|
- 44. o aminobenzoate
- [ ] (UMLS (CSP) C0178778) =Organic Chemical =benzoate;
| - 94. Oat Cell Carcinoma of Extrahepatic Bile Duct
- (UMLS (NCI) C1335979) Oat Cell Carcinoma of the Extrahepatic Bile Duct;
Oat Cell Extrahepatic Bile Duct Carcinoma; Small Cell Adenocarcinoma of Extrahepatic Bile Duct; Small Cell Adenocarcinoma of the Extrahepatic Bile Duct; Small Cell Extrahepatic Bile Duct Carcinoma; =Neoplastic Process ; |
- 45. O antigen
- [The lipopolysaccharide-protein somatic antigens, usually from gram-negative bacteria, important in the serological classification of enteric bacilli. The O-specific chains determine the specificity of the O antigens of a given serotype. O antigens are the immunodominant part of the lipopolysaccharide molecule in the intact bacterial cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed) ( MSH )] (UMLS (CSP) C0069180) =Carbohydrate; Immunologic Factor ;
| - 95. Oat Cell Carcinoma of Prostate
- [A neuroendocrine carcinoma of the prostate gland with unfavorable prognosis, composed of small cells containing neurosecretory granules. Approximately half of the cases show a mixture of small cells and adenocarcinoma cells. ( NCI )] (UMLS (NCI) C1300585) Oat Cell Carcinoma of the Prostate;
Prostate Oat Cell Carcinoma; Prostate Small Cell Carcinoma; Small Cell Carcinoma of Prostate; Small Cell Carcinoma of the Prostate =Neoplastic Process |
- 46. O glycosidase
- [ ] (UMLS (CSP) C0597123) =Amino Acid, Peptide, or Protein; Enzyme =glycosidase;
=alpha galactosidase; alpha glucosidase; amylase; beta galactosidase; beta glucosidase; beta N acetylhexosaminidase; acid maltase; glucocerebrosidase; beta glucuronidase; chondroitinase; mannosidase; lysozyme; exo alpha sialidase; beta fructofuranosidase; LACTASE; N acetylglucosaminidase | - 96. oat sterile dwarf virus
- [ ] (UMLS (CSP) C0599312) =Virus ;
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- 47. O methylglucose
- [ ] (UMLS (CSP) C0598522) =Carbohydrate ;
| - 97. oats
- [ ] (UMLS (CSP) C0028753) =Food
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- 48. O'nyong-nyong virus
- [ ] (UMLS (CSP) C0318742) =Virus
| - 98. OB AIR EMBOL-DELIV W P/P
- [ ] (UMLS (ICD9CM) C0157544) =Disease or Syndrome
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- 49. O,O-diethyl-S-[2(diethylamino)ethyl]phosphorothioate
- [ ] (UMLS (CSP) C1113674) =Organic Chemical; Hazardous or Poisonous Substance
| - 99. OB AIR EMBOLISM-ANTEPART
- [ ] (UMLS (ICD9CM) C0157545) =Disease or Syndrome
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- 50. O-ethyl-S-[2(diethylamino)ethyl]ethylphosphonothioate
- [ ] (UMLS (CSP) C1113675) =Organic Chemical; Hazardous or Poisonous Substance
| - 100. OB AIR EMBOLISM-DELIVER
- [ ] (UMLS (ICD9CM) C0157543) =Disease or Syndrome
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