[Expressed in a variety of tissues (abundantly in erythroid stem cells to differentiated reticulocytes) by human MPP1 Gene (MAGUK Family), 466-aa 52-kDa Palmitoylated Membrane Protein 1 contains 1 PDZ/DHR domain, 1 conserved SH3 domain, 1 guanylate kinase-like domain, and a region that binds to cytoskeletal protein 4.1. Tightly associated with the plasma membrane and extensively palmitoylated, MPP1 interacts with DLG5 and is suspected to play a role in signal transduction. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. (NCI) ( NCI )]
UMLS (NCI) C1335296EMP55
Erythrocyte Membrane Protein p55
p55
Palmitoylated Membrane Protein 1
Palmitoylated Membrane Protein 1 55kD
PEMP
- Amino Acid, Peptide, or Protein
- Biologically Active Substance