[A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation. (NCI04) ( NCI )]
UMLS (NCI) C0025828 - Nucleic Acid, Nucleoside, or Nucleotide
- Pharmacologic Substance