- 1. (+)-4-Amino-3-isoxazolidinone
- [An analogue of the amino acid D-alanine with broad-spectrum antibiotic and glycinergic activities. D-cycloserine interferes with bacterial cell wall synthesis by competitively inhibiting two enzymes, L-alanine racemase and D-alanine:D-alanine ligase, thereby impairing peptidoglycan formation necessary for bacterial cell wall synthesis. This agent may be bactericidal or bacteriostatic, depending on its concentration at the infection site and the susceptibility of the organism. In addition, D-cycloserine is an excitatory amino acid and partial agonist at the glycine binding site of the NMDA receptor in the central nervous system (CNS); binding to the central NMDA receptor may result in amelioration of neuropathic pain. ( NCI )] (UMLS (NCI) C0010590) =Amino Acid, Peptide, or Protein; Antibiotic =2-Amino-3-hydroxypropionic Acid;
[AM500] ANTITUBERCULARS =CYCLOSERINE 250 MG; | - 51. (Aorto)coronary bypass of two coronary arteries
- [ ] (UMLS (ICD9CM) C0190228) =Therapeutic or Preventive Procedure
|
- 2. (+)-6-[Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
- [An anticancer drug that inhibits the transformation of normal cells to cancer cells. It belongs to the family of drugs called enzyme inhibitors. ( NCI )] (UMLS (NCI) C1176289) Tipifarnib;
=Organic Chemical; Pharmacologic Substance | - 52. (asterisk) Life of the "unit." Used for blood products.
- (UMLS (HL7) C1547057) =Temporal Concept =Duration categories;
|
- 3. (+)-A 127722
- (UMLS (NCI) C0663262) =Organic Chemical; Pharmacologic Substance ;
| - 53. *Activity
- (UMLS (HL7) C1561536) =Idea or Concept =Kind of quantity;
|
- 4. (+)-Aldosterone
- [hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. ( CSP )] (UMLS (NCI) C0002006) =Steroid; Pharmacologic Substance; Hormone
| - 54. *Arbitrary
- (UMLS (HL7) C1264693) =Quantitative Concept =Kind of quantity;
|
- 5. (+)-alpha-Tocopherol
- [A naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acids), d-alpha-Tocopherol is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. Vitamin E also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04) ( NCI )] (UMLS (NCI) C0969677) .alpha. Tocopherol;
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol; alpha Tocopherol; ALPHA-TOCOPHEROL; d-Alpha-Tocopherol; Tocopherol-Alpha; Tocopherol-D-Alpha; =Lipid; Pharmacologic Substance; Vitamin | - 55. .alpha.-Linolenic acid
- [An essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostaglandin resulting in reduced inflammation and prevention of certain chronic diseases. ( NCI )] (UMLS (NCI) C0051405) =Lipid; Biologically Active Substance ;
=Fatty Acids, Omega-3; Linolenic Acids =LINOLENIC ACID |
- 6. (+)-alpha-Tocopherol Acetate
- [The acetate ester of a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acid), vitamin E is a generic name for a group of compounds known as tocopherols and tocotrienols (tocols). This agent is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. Vitamin E also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04) ( NCI )] (UMLS (NCI) C0078373) =Organic Chemical; Pharmacologic Substance; Vitamin =(+/-)-alpha-Tocopherol;
(+)-alpha-Tocopherol Acetate; Unclassified Ingredient Preparations; =(+)-alpha-Tocopherol Acetate; THICKENUP POWDER; TOCOPHERYL ACETATE,ALPHA 15 MG; TOCOPHERYL ACETATE,ALPHA 30 UNT; OMEGA-3 (N-3) POLYUNSATURATED FATTY ACIDS 1GM CAP; TOCOPHERYL ACETATE,D-ALPHA 30 MG; VITAMIN E ACETATE 30 IU; VITAMIN E ACETATE 30 UNT; | - 56. 1 aminocyclopentyl 1,3 dicarboxylate
- [ ] (UMLS (CSP) C0044270) =Organic Chemical; Pharmacologic Substance ;
|
- 7. (+-)-2-Amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide Monohydrochloride
- [The hydrochloride salt form of midodrine, a direct-acting prodrug and sympathomimetic agent with antihypotensive properties. Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier, and is therefore not associated with effects on the central nervous system. ( NCI )] (UMLS (NCI) C0733394) 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol Hydrochloride;
MIDODRINE HYDROCHLORIDE; MIDODRINE HYDROCHLORIDE PREPARATION; Midodrine Monohydrochloride =Organic Chemical; Pharmacologic Substance =MIDODRINE; =MIDODRINE HYDROCHLORIDE 2.5 MG; MIDODRINE HYDROCHLORIDE 5 MG; MIDODRINE HYDROCHLORIDE 10 MG | - 57. 1,1a,2,2,3,3a,4,5,5,5a,5b,6-Dodecachloro-octahydro-1,3,4-metheno-1H-cyclbuta[cd]pentalene
- [A white, stable, odorless, synthetic, crystalline solid chlorinated hydrocarbon. Mirex was used as an insecticide against ants and as a fire-retardant for plastics, paint, rubber, paper and electrical appliances, but it is no longer produced or used in the US. Exposure to Mirex irritates the skin and eyes and causes a headache as well as dizziness, nausea and vomiting and affects the central nervous system, lungs, liver and kidneys. Mirex is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0026209) =Organic Chemical; Hazardous or Poisonous Substance
|
- 8. (+-)-alpha-((tert-Butylamino)methyl)-3,5-dihydroxybenzyl Alcohol Sulfate(2:1)(salt)
- [The sulfate salt form of terbutaline, an ethanolamine derivative with bronchodilating and tocolytic properties. Terbutaline sulfate selectively binds to and activates beta-2 adrenergic receptors, leading to intracellular adenyl cyclase activation via a trimeric G protein and subsequent increase in cyclic cAMP production. Increased cAMP levels result in relaxation of bronchial and vascular smooth muscle mediated through the activation of protein kinase A (PKA), which phosphorylates proteins in control of muscle tone. cAMP also inhibits calcium ion release from intracellular stores, reduces calcium entry into cells and induces the sequestration of intracellular calcium all of which aids the relaxation of airway muscles. Terbutaline sulfate also increases mucociliary clearance and reduces release of inflammatory cell mediators. ( NCI )] (UMLS (NCI) C0039543) =Organic Chemical; Pharmacologic Substance ;
=TERBUTALINE; =TERBUTALINE SULFATE 1 MG/ML; TERBUTALINE SULFATE 2.5 MG; TERBUTALINE SULFATE 5 MG | - 58. 1,2,3,4,4a,4b,7,9,10,10a-Decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthrenepropionic Acid Delta-Lactone
- [A progesterone derivative with antineoplastic activity. Testolactone inhibits steroid aromatase, thereby preventing the formation of estrogen from adrenal androstenedione and reducing endogenous estrogen levels. (NCI04) ( NCI )] (UMLS (NCI) C0039600) =Steroid; Pharmacologic Substance; Hormone =Androstadienes;
Homosteroids; [AN500] ANTINEOPLASTIC HORMONES; =TESTOLACTONE 50 MG |
- 9. (+/-)-alpha-Tocopherol
- [A substance used in cancer prevention. It belongs to the family of drugs called tocopherols. ( NCI )] (UMLS (NCI) C0042874) =Lipid; Pharmacologic Substance; Vitamin =benzopyran;
[DE350] EMOLLIENTS; (+/-)-alpha-Tocopherol; [VT000] VITAMINS =(+)-alpha-Tocopherol Acetate; VITAMIN E OIL; TOCOPHERYL ACID SUCCINATE,D-ALPHA; TOCOPHEROL,DL-ALPHA; (+)-alpha-Tocopherol Acetate; AMINOBENZOIC ACID LOTION (ML); PEPTAMEN LIQUID UNFLAVORED,250ML; PEPTAMEN LIQUID VANILLA,250ML; ALOE VERA/VITAMIN E OIL,TOP; CARA-KLENZ,SKIN & WOUND CLEANSER; CARRINGTON INCONTINENCE SKIN KIT; ISOCAL HN (VANILLA) LIQUID,240ML; ISOCAL LIQUID,CAN,240ML; ISOCAL LIQUID,CAN,360ML; More… | - 59. 1-((6-Allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea
- [A synthetic ergoline derivative and a long-acting dopamine receptor agonist with high affinity for the dopamine D2 receptor. Cabergoline exerts an inhibitory effect on prolactin secretion by acting on dopamine receptors present in pituitary lactotrophes. This drug also binds to dopamine D2 receptors in the corpus striatum, thereby mimicking the actions of dopamine on motor control. Cabergoline also possesses antioxidant and neuroprotective properties due to its free radical scavenging activity. Cabergoline is used in the treatment of Parkinson's disease and in the treatment of hyperprolactinemia. ( NCI )] (UMLS (NCI) C0107994) =Organic Chemical; Pharmacologic Substance =ergoline;
[AU900] AUTONOMIC AGENTS, OTHER =CABERGOLINE 0.5 MG |
- 10. (-)-alpha-(1-Aminoethyl)-3,4-dihydroxybenzyl Alcohol
- [The levoisomer of nordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin's antihypertensive effect is exerted through activation of alpha 2-adrenergic receptors in the cardiovascular control center of the CNS thereby suppressing the sympathetic output from the brain and subsequently lowering blood pressure. Levonordefrin binds to and activates peripheral alpha 2- adrenergic receptors, thereby causing vasoconstriction. ( NCI )] (UMLS (NCI) C0520472) =Organic Chemical; Pharmacologic Substance ;
=Nordefrin; [DE700] LOCAL ANESTHETICS, TOPICAL =LEVONORDEFRIN 1:20000 | - 60. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine
- [1-(4-amino-6,7-dimethoxy- 2-quinazolinyl) -4-(2-furoyl) piperazine. ( CSP )] (UMLS (NCI) C0032912) =Organic Chemical; Pharmacologic Substance ;
=antihypertensive agent; PIPERAZINE; quinazoline; [CV150] ALPHA-BLOCKERS/RELATED =Terazosin; DOXAZOSIN; PRAZOSIN HYDROCHLORIDE; PRAZOSIN 5 MG; PRAZOSIN 1 MG |
- 11. (--)-2Amino-3-)3,4-dihydroxyphenyl)propanoic Acid
- [naturally occuring form of DOPA and precursor of dopamine; used as an antiparkinsonian agent; unlike dopamine it can be administered orally. ( CSP )] (UMLS (NCI) C0023570) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine ;
=[CN500] ANTIPARKINSON AGENTS; dihydroxyphenylalanine =LEVODOPA 100 MG; LEVODOPA 200 MG; LEVODOPA 250 MG; Carbidopa 12.5 MG / entacapone 200 MG / Levodopa 50 MG Oral Tablet; LEVODOPA 150 MG | - 61. 1-(alpha-methoxymethyl ethanol)-2-Nitroimidazole
- [1-(alpha-methoxymethyl ethanol)-2-nitroimidazole; trichimonicide and experimental mutagen and radiosensitizer, probably due to its ability to form DNA-attacking free radical under hypoxic conditions. ( CSP )] (UMLS (NCI) C0026218) =Organic Chemical; Pharmacologic Substance =Antiprotozoal Agent;
imidazole; Radiation Sensitizers; |
- 12. (1 Alpha,11 alpha)-11-(acetyloxy)-1-(methoxymethyl)-2-oxaandrosta-5,8-dieno(6,5,4-bc)furan- 3,7,17-trione
- [A potent fungal metabolite isolated from Penicillium wortmannin that selectively inhibits phosphatidylinositol 3-kinase and affects the signal transduction pathway. (NCI) ( NCI )] (UMLS (NCI) C0078517) =Steroid; Pharmacologic Substance; Biologically Active Substance
| - 62. 1-(aminomethyl)cyclohexaneacetic Acid
- [A substance that is being studied as a treatment for relieving hot flashes in women with breast cancer. It belongs to the family of drugs called anticonvulsants. ( NCI )] (UMLS (NCI) C0060926) =Organic Chemical; Pharmacologic Substance ;
=Acetic Acids; [CN400] ANTICONVULSANTS =GABAPENTIN 100 MG; GABAPENTIN 300 MG; GABAPENTIN 400 MG; GABAPENTIN 600 MG; GABAPENTIN 800 MG; GABAPENTIN 250 MG/5ML |
- 13. (11alpha,13E)-(+-)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic Acid Methyl Ester
- [A radioprotective agent that belongs to the family of drugs called prostaglandins. ( NCI )] (UMLS (NCI) C0085174) =Eicosanoid; Pharmacologic Substance =Prostaglandins E, Synthetic;
[GA309] ANTIULCER AGENTS, OTHER =Misoprostol 0.2 MG; Misoprostol 0.1 MG; | - 63. 1-ABaP
- [A polycyclic aromatic hydrocarbon belongs to the family of mutagen benzo(a)pyrene. 1-aminobenzo(a)pyrene consists of five fused rings with an amino-group attached to the first carbon atom of the aromatic hydrocarbon ring with potential carcinogenicity. ( NCI )] (UMLS (NCI) C0768966) 1-Aminobenzo[a]pyrene;
=Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance |
- 14. (11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic Acid
- [The naturally occuring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3'5'-cAMP. ( NCI )] (UMLS (NCI) C0002335) =Eicosanoid; Pharmacologic Substance ;
| - 64. 1-Acetamido-4-ethoxybenzene
- [A synthetic, white crystalline solid that is slightly soluble in water and benzene, soluble in acetone and very soluble in pyrimidine. It is used in research as the preferred marker for detecting CYP1A2-based inhibition potential in vitro. Human ingestion of phenacetin can result in a bluish discoloration of the skin due to a lack of oxygen in the blood (cyanosis), dizziness and respiratory depression. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0031364) =Organic Chemical; Pharmacologic Substance =Acetanilides;
[CN850] ANTIPYRETICS; [CN103] NON-OPIOID ANALGESICS; TO BE DELETED INGREDIENT PREPARATIONS; Unclassified Ingredient Preparations; |
- 15. (17-alpha)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one
- [A synthetic form of the naturally occurring female sex hormone progesterone. Etonogestrel binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression. As a result of the negative feedback mechanism, luteinizing hormone (LH) release is inhibited, which leads to an inhibition of ovulation and an alteration in the cervical mucus and endometrium. ( NCI )] (UMLS (NCI) C0047683) =Steroid; Pharmacologic Substance ;
=[HS200] CONTRACEPTIVES, SYSTEMIC; Unclassified Ingredients =ETONOGESTREL 0.12 MG | - 65. 1-Acetyl-2-picolinoylhydrazine
- [A hydrazine compound that has been investigated for antineoplastic activity. (NCI04) ( NCI )] (UMLS (NCI) C0052754) =Organic Chemical; Pharmacologic Substance
|
- 16. (17Alpha)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one
- [The levorotatory form of norgestrel and synthetic progestogen with progestational and androgenic activity. Levonorgestrel binds to the progesterone receptor in the nucleus of target cells, thereby stimulating the resulting hormone-receptor complex, initiating transcription, and increasing the synthesis of certain proteins. This results in a suppression of luteinizing hormone (LH) activity and an inhibition of ovulation, as well as an alteration in the cervical mucus and endometrium. ( NCI )] (UMLS (NCI) C0023566) =Steroid; Pharmacologic Substance; Hormone ;
=female antifertility drug; (+/-)-13-Ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one; [HS800] PROGESTINS; [HS200] CONTRACEPTIVES, SYSTEMIC =LEVONORGESTREL 0.05 MG; LEVONORGESTREL 0.15 MG; LEVONORGESTREL 0.25 MG; LEVONORGESTREL 0.1 MG; LEVONORGESTREL 0.75 MG; LEVONORGESTREL 36 MG; LEVONORGESTREL 0.05-0.125 MG; LEVONORGESTREL 52 MG; | - 66. 1-Allyl-3,4-methylenedioxybenzene
- [A naturally-occurring, colorless to slightly yellow liquid that is soluble in ethanol, ether, and chloroform. Safrole is no longer used in the United States. Minimal exposure to safrole may occur through the use of edible spices, including nutmeg and mace, which contain low levels of this compound. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0036049) =Organic Chemical; Hazardous or Poisonous Substance
|
- 17. (17alpha)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol
- [semisynthetic alkylated estradiol with a 17-alpha-ethinyl substitution; has high estrogenic potency when administered orally, and is often used as the estrogenic component in oral contraceptives. ( CSP )] (UMLS (NCI) C0015011) =Steroid; Pharmacologic Substance; Hormone =[HS300] ESTROGENS;
estrogen analog; Norpregnatrienes; =(17alpha)-3-Methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17-ol; QUINESTROL; ETHINYL ESTRADIOL 0.03 MG; ETHINYL ESTRADIOL 0.5 MG; ETHINYL ESTRADIOL 0.02 MG; ETHINYL ESTRADIOL 0.05 MG; ETHINYL ESTRADIOL 0.035 MG; ETHINYL ESTRADIOL 0.01 MG; ETHINYL ESTRADIOL 0.025 MG; ETHINYL ESTRADIOL 0-35 MCG; ETHINYL ESTRADIOL 0.015 MG; ETHINYL ESTRADIOL 0.03-0.04 MG; ETHINYL ESTRADIOL 0.25 MG; {7 (Ethinyl Estradiol 0.035 MG / Norethindrone 0.5 MG Oral Tablet) / 7 (Ethinyl Estradiol 0.035 MG / Norethindrone 0.75 MG Oral Tablet) / 7 (Ethinyl Estradiol 0.035 MG / Norethindrone 1 MG Oral Tablet) / 7 (Inert Ingredients 1 MG Oral Tablet) } Pack [Necon 7/7/7 28 Day]; {21 (Ethinyl Estradiol 0.03 MG / Norgestrel 0.3 MG Oral Tablet) / 7 (Inert Ingredients 1 MG Oral Tablet) } Pack [Lo/Ovral 28 Day] | - 67. 1-Amino-2,4-dibromo-9,10-anthracenedione
- [A synthetic, light sensitive, red powder that is insoluble in water and soluble in many organic solvents. It is used as both an intermediate for the production of anthraquinone dyes and as a starting material for the manufacture of vat dyes. The primary route of potential human exposure to 1-amino-2,4-dibromoanthraquinone is dermal contact. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0626387) =Organic Chemical
|
- 18. (17alpha)-3-Methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17-ol
- [A semisynthetic estrogen. Metabolized by the liver to ethynyl estradiol, mestranol serves as the estrogen component in several combination oral contraceptives. (NCI04) ( NCI )] (UMLS (NCI) C0025506) =Steroid; Pharmacologic Substance =[HS300] ESTROGENS;
(17alpha)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol =MESTRANOL 0.1 MG; MESTRANOL 0.15 MG; MESTRANOL 0.05 MG; MESTRANOL 50 MCG | - 68. 1-Amino-2-methyl-9,10-anthracenedione
- [A synthetic, red powder that is insoluble in water and soluble in acetone, ethanol, ether, benzene, chloroform and acetic acid. It is used almost exclusively as a dye and dye intermediate for the production of a variety of anthraquinone dyes. The primary routes of potential human exposure to 1-amino-2-methylanthraquinone are inhalation and dermal contact. However, human exposure is limited because this compound is no longer produced in the United States. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0044271) =Organic Chemical
|
- 19. (17alpha)-Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol
- [A synthetic hormone that belongs to the family of drugs called androgens and is used to treat endometriosis. It is being evaluated in the treatment of endometrial cancer. ( NCI )] (UMLS (NCI) C0010961) =Steroid; Pharmacologic Substance =Pregnadienes;
[HS100] ANDROGENS/ANABOLICS =DANAZOL 100 MG; DANAZOL 50 MG; DANAZOL 200 MG; | - 69. 1-amino-3,5-dimethyladamantane Hydrochloride
- [The hydrochloride salt form of memantine, a moderate affinity, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine hydrochloride exerts its effect by binding to the cation channels on the NMDA receptor located in the central nervous system, thereby blocking the NMDA receptor and preventing the binding of the excitatory amino acid glutamate. This results in a reduction of abnormal excitement in the brain, which is often seen in Alzheimer's disease. Memantine hydrochloride also acts as an antagonist at the 5HT 3 receptor and the nicotinic receptor. ( NCI )] (UMLS (NCI) C0771988) Ebixia;
MEMANTINE HYDROCHLORIDE =Organic Chemical; Pharmacologic Substance ; |
- 20. (1alpha,2alpha,3beta,4alpha,5alpha,6beta)1,2,3,4,5,6-Hexachlorocyclohexane
- [gamma isomer of benzene hexachloride, a carcinogenic insecticide more potent than DDT (chlorophenothane); it is used to kill lice and mites, applied topically to the skin. ( CSP )] (UMLS (NCI) C0005038) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 70. 1-Amino-6,17-dihydroxy-7,10,18,21-tetraoxo-27-(n-acetylhydroxylamino)-6,11,17,22-tetraazaheptaeicosane
- [natural product isolated from Streptomyces pilosus; it forms iron complexes and is used as a chelating agent, particularly in the mesylate form. ( CSP )] (UMLS (NCI) C0011145) =Organic Chemical; Biologically Active Substance; Indicator, Reagent, or Diagnostic Aid =chelating agent;
Hydroxamic Acids; hydroxamate; [AD300] HEAVY METAL ANTAGONISTS =DEFEROXAMINE MESYLATE; |
- 21. (1alpha,3beta,5Z,7E)-9,10-Secocholesta-3,7,10(19),16-tetraene-1,3,25-triol
- (UMLS (NCI) C0255545) =Steroid; Pharmacologic Substance ;
| - 71. 1-Aminocyclopentane
- [A synthetic amino acid derivative of cyclopentanecarboxylic acid, Cycloleucine displays immunosuppressive, antineoplastic, and cytostatic properties. Believed to act in vivo as a valine antagonist and an NMDA receptor antagonist acting at the glycine site, Cycloleucine is a competitive inhibitor of many enzymes, such as methionine adenosyltransferase (S-adenosylmethionine biosynthesis). Toxicity is correlated with a block of nucleic acid methylation; cell cycle progression; and DNA, RNA and protein biosynthesis. (NCI04) ( NCI )] (UMLS (NCI) C0010575) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 22. (1alpha,3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
- [most biologically active metabolite of cholecalciferol; acts via a DNA-binding steroid receptor which induces transcription of calcium transport factors in gut; USP drug (calcitriol) is given as an antihypocalcemic. ( CSP )] (UMLS (NCI) C0006674) =Steroid; Pharmacologic Substance; Hormone; Vitamin =(1alpha,3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol;
Dihydroxycholecalciferols; [VT500] VITAMIN D; steroid hormone =Calcipotriene; (1alpha,3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; Calcitriol 0.00025 MG; Calcitriol 0.0005 MG; Calcitriol 0.001 MG/ML; Calcitriol 0.002 MG/ML | - 72. 10a
- [Maxillary left lateral incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553642) =Medical Device =Artificial dentition;
|
- 23. (1alpha,3beta,5Z,7E)-9,10-Secostigmasta-5,7,10(19)-triene-1,3-diol
- (UMLS (NCI) C0534957) =Steroid ;
| - 73. 11a
- [Maxillary left canine abutment ( HL7V3.0 )] (UMLS (HL7) C1553643) =Medical Device =Artificial dentition;
|
- 24. (1alpha,3beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diol
- [A substance that is being studied in the prevention of recurrent prostate cancer. It belongs to the family of drugs called vitamin D analogs. ( NCI )] (UMLS (NCI) C0043668) =Steroid; Pharmacologic Substance; Vitamin =Ergocalciferols;
[VT509] VITAMIN D, OTHER =Doxercalciferol 0.002 MG/ML; DOXERCALCIFEROL 0.0025 MG; | - 74. 12-Allyldeoxoartemisinin
- [A semi-synthetic analogue of Artemisinin - a sesquiterpene lactone extracted from the dry leaves of Artemisia Annua (sweet wormwood) used as anti-malaria agent. Limited data is available on Artemisinin antineoplastic activity. ( NCI )] (UMLS (NCI) C0294412) =Organic Chemical; Pharmacologic Substance ;
|
- 25. (1aR,2Z,4E,14R,15aR)-8-Chloro-1a,14,15,15a-Tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione
- [A macrocyclic antifungal antibiotic that inhibits signal-dependent transcriptional activation and induces differentiation in leukemia. (NCI) ( NCI )] (UMLS (NCI) C0207800) =Organic Chemical; Pharmacologic Substance ;
| - 75. 12a
- [Maxillary left first premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553644) =Medical Device =Artificial dentition;
|
- 26. (1aS,8S,8aR,8bS)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
- [antineoplastic antibiotic produced by Streptomyces caespitosus that acts as an alkylating agent causing cross-linking of DNA and inhibition of DNA synthesis. ( CSP )] (UMLS (NCI) C0002475) =Organic Chemical; Antibiotic
| - 76. 13a
- [Maxillary left second premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553645) =Medical Device =Artificial dentition;
|
- 27. (2alpha,3beta)-2,3,23-Trihydroxyurs-12-en-28-oic acid, O-6-deoxy-alpha-L-mannopyranosyl-(1--4)--beta-D-glucopyranosyl-(1--6)-O-beta-D-glucopyranosyl Ester
- (UMLS (NCI) C0052506) =Organic Chemical; Pharmacologic Substance
| - 77. 14a
- [Maxillary left first molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553646) =Medical Device =Artificial dentition;
|
- 28. (3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid
- [A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract. ( NCI )] (UMLS (NCI) C0042105) =Steroid; Pharmacologic Substance; Biologically Active Substance =Deoxycholic Acid;
(3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid; [GA900] GASTRIC MEDICATIONS, OTHER; =(3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid; URSODIOL 250 MG; Ursodeoxycholate 300 MG | - 78. 15a
- [Maxillary left second molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553647) =Medical Device =Artificial dentition;
|
- 29. (4-Amino-1-hydroxybutylidene)bisphosphonic Acid
- [bone resorption inhibitor. ( CSP )] (UMLS (NCI) C0102118) =Organophosphorus Compound; Pharmacologic Substance ;
=inhibitor/antagonist; biphosphonate; [HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER; =ALENDRONATE 70 MG; ALENDRONATE 35 MG; ALENDRONATE 10 MG; ALENDRONATE 5 MG; ALENDRONATE 40 MG; | - 79. 16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure
- [A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect. ( NCI )] (UMLS (NCI) C0027444) =Organic Chemical; Antibiotic =macrolide antibiotic;
[OP202] ANTIFUNGALS, TOPICAL OPHTHALMIC =NATAMYCIN 5 %WV; |
- 30. (4Alpha,5alpha,17beta)-4,5-epoxy-3,17-dihydroxyandrost-2-ene-2-carbonitrile
- [A synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex, resulting in the decreased synthesis of mineralocorticoids and glucocorticoids and the decreased conversion of pregnenolone to progesterone. (NCI04) ( NCI )] (UMLS (NCI) C0077144) =Steroid; Pharmacologic Substance =Stanolone;
[HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER; TO BE DELETED INGREDIENT PREPARATIONS; =TRILOSTANE 60 MG; TRILOSTANE 30 MG; | - 80. 16a
- [Maxillary left third molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553648) =Medical Device =Artificial dentition;
|
- 31. (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride
- [The hydrochloride salt form of naltrexone, a noroxymorphone derivative with competitive opioid antagonistic property. Naltrexone reverses the effects of opioid analgesics by binding to the various opioid receptors in the central nervous system, including the mu-, kappa- and gamma-opioid receptors. This leads to an inhibition of the typical actions of opioid analgesics, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. Naltrexone is longer-acting and more potent compared to naloxone. ( NCI )] (UMLS (NCI) C0355800) =Organic Chemical; Pharmacologic Substance =NALTREXONE;
=NALTREXONE HYDROCHLORIDE 50 MG | - 81. 16alpha-Fluoroandrost-5-en-17-one
- (UMLS (NCI) C0539515) =Steroid; Pharmacologic Substance ;
|
- 32. (5alpha,17beta)-17-Hydroxyandrostan-3-one
- [potent androgenic metabolite of testosterone; dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone; unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid. ( CSP )] (UMLS (NCI) C0038148) =Steroid; Pharmacologic Substance; Hormone =androgen;
Androstanols =(4Alpha,5alpha,17beta)-4,5-epoxy-3,17-dihydroxyandrost-2-ene-2-carbonitrile | - 82. 17 Alpha-methyl-delta4-androsten-17beta-ol-4-one
- (UMLS (NCI) C1449554) =Steroid; Pharmacologic Substance
|
- 33. (5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
- [orally active testosterone 5-alpha reductase inhibitor, used as an alternative to surgery for treatment of benign prostatic hyperplasia. ( CSP )] (UMLS (NCI) C0060389) =Steroid; Pharmacologic Substance ;
=Androstenes; [AN000] ANTINEOPLASTICS; Azasteroids; enzyme inhibitor; [HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER; =FINASTERIDE 1 MG; FINASTERIDE 5 MG | - 83. 17-(Acetyloxy)-6-chloropregna-4,6-diene-3,20-dione
- [An orally active synthetic progestational hormone used often in combinations as an oral contraceptive. ( MSH )] (UMLS (NCI) C0008214) =Steroid; Pharmacologic Substance ;
|
- 34. (5alpha,6alpha)-17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol Hydrochloride
- [The hydrochloride salt form of nalbuphine, a synthetic phenanthrene opioid with opiate agonist and antagonist effects, used to treat moderate to severe pain and provide preoperative and postoperative analgesia and sedation. Nalbuphine hydrochloride binds to kappa-, mu- and delta-opioid receptors but not to sigma-opioid receptors. This opioid exerts its analgesic actions primarily through kappa-opioid-receptor agonism and partially through mu-opioid receptor agonism. ( NCI )] (UMLS (NCI) C0600099) =Organic Chemical; Pharmacologic Substance =NALBUPHINE;
=NALBUPHINE HYDROCHLORIDE 20 MG/ML; NALBUPHINE HYDROCHLORIDE 1.5 MG/ML; NALBUPHINE HYDROCHLORIDE 10 MG/ML | - 84. 17-(Allylamino)-17-demethoxygeldanamycin
- [A benzoquinone antineoplastic antibiotic derived from the antineoplastic antibiotic geldanamycin. Tanespimycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins; the inhibition of HSP90 promotes the proteasomal degradation of oncogenic signaling proteins that may be overexpressed by tumor cells. ( NCI )] (UMLS (NCI) C0675974) =Organic Chemical; Antibiotic ;
|
- 35. (6alpha)-17-(Acetyloxy)-6-methylpregn-4-ene-3,20-dione
- [A synthetic, acetate derivative of the sex hormone progesterone. Medroxyprogesterone 17-acetate (NCI04) ( NCI )] (UMLS (NCI) C0065864) =Steroid; Pharmacologic Substance; Hormone =(6Alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione;
=MEDROXYPROGESTERONE ACETATE 14 TABS X 5 MG; MEDROXYPROGESTERONE ACETATE DAY15-28 X 5 MG; MEDROXYPROGESTERONE ACETATE 5 MG; MEDROXYPROGESTERONE ACETATE 2.5 MG; MEDROXYPROGESTERONE ACETATE 100 MG/ML; MEDROXYPROGESTERONE ACETATE 10 MG; MEDROXYPROGESTERONE ACETATE 25 MG; MEDROXYPROGESTERONE ACETATE 400 MG/ML; MEDROXYPROGESTERONE ACETATE 150 MG/ML; | - 85. 17a
- [Mandibular left third molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553649) =Medical Device =Artificial dentition;
|
- 36. (6Alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione
- [synthetic progestin derived from 17-hydroxyprogesterone; a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms. ( CSP )] (UMLS (NCI) C0025147) =Steroid; Pharmacologic Substance; Hormone =[HS800] PROGESTINS;
17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione; progesterone analog; =(6alpha)-17-(Acetyloxy)-6-methylpregn-4-ene-3,20-dione | - 86. 17ad
- [Mandibular left third molar abutment distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1553651) =Medical Device =Artificial dentition;
|
- 37. (6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
- [synthetic glucocorticoid derived from progesterone, used in replacement therapy for adrenal insufficiency and as an anti-inflammatory and immunosuppressant. ( CSP )] (UMLS (NCI) C0025815) =Steroid; Pharmacologic Substance; Hormone =[HS051] GLUCOCORTICOIDS;
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione =(7alpha,11beta,16alpha)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione; 11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-Acetate; METHYLPREDNISOLONE SODIUM SUCCINATE; 11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-Acetate; METHYLPREDNISOLONE SODIUM SUCCINATE; METHYLPREDNISOLONE 2 MG; METHYLPREDNISOLONE 24 MG; METHYLPREDNISOLONE 32 MG; METHYLPREDNISOLONE 8 MG; METHYLPREDNISOLONE 16 MG; METHYLPREDNISOLONE 4 MG | - 87. 17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione
- [principal progestational hormone, secreted by the corpus luteum, placenta, and in minute amounts by the adrenal cortex; it prepares the uterus for the reception and development of the fertilized ovum; it acts on the mammary glands and on the brain; it serves as an intermediate in the biosynthesis of sex steroids and adrenal corticosteroids. ( CSP )] (UMLS (NCI) C0033308) =Steroid; Pharmacologic Substance; Hormone =C21 steroid;
Pregnenediones; [HS800] PROGESTINS; gonadal steroid hormone =HYDROXYPROGESTERONE; (6Alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione; PROGESTERONE 2.5 MG; PROGESTERONE 25 MG/ML; PROGESTERONE 50 MG/ML; PROGESTERONE 100 MG; PROGESTERONE PWDR; PROGESTERONE 200 MG; PROGESTERONE 8 %; PROGESTERONE 4 %; |
- 38. (6alpha,11beta,16alpha)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
- [A synthetic glucocorticoid and derivative of fluocinolone acetonide with anti-inflammatory and antipruritic activity. Fluocinonide binds the glucocorticoid receptor, followed by translocation of the ligand-receptor complex to the nucleus and transcription activation of genes containing glucocorticoid-responsive elements. Lipocortin-1 is one factor induced by fluocinonide that interacts and inhibits cytosolic phospholipase 2 alpha, thereby preventing phospholipase translocation to the perinuclear membrane and subsequent release and conversion of arachidonic acid to inflammatory prostaglandins. In addition, MAPK phosphatase 1 is induced, thereby preventing the triggering of the MAPK cascade resulting in pro-inflammatory effects via Jun N-terminal kinase and c-Jun. Finally, fluocinonide binds to and inhibits nuclear factor kappa-B directly, resulting in inhibition of cyclooxygenase 2 transcription and subsequent prostaglandin synthesis. ( NCI )] (UMLS (NCI) C0016299) =Steroid; Pharmacologic Substance ;
=(6alpha,11beta,16alpha)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione; [DE200] ANTI-INFLAMMATORY, TOPICAL =FLUOCINONIDE 0.05 % | - 88. 17am
- [Mandibular left third molar abutment mesial hemisection ( HL7V3.0 )] (UMLS (HL7) C1553650) =Medical Device =Artificial dentition;
|
- 39. (6alpha,11beta,16alpha)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
- [The acetonide salt form of fluocinolone, a synthetic fluorinated corticosteroid with antiinflammatory, antipruritic and vasoconstrictive properties. Fluocinolone is a glucocorticoid receptor agonist that binds to cytoplasmic glucocorticoid receptors and subsequently translocates to the nucleus where it initiates the transcription of glucocorticoid-responsive genes such as lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both are potent mediators of inflammation. Fluocinolone exerts its vasoconstrictive effect through inhibition of nitric oxide synthase, thereby blocking nitric oxide production and effectively diminishing the effect of nitric oxide on vascular smooth muscles leading to reduced blood flow. ( NCI )] (UMLS (NCI) C0016298) =Steroid; Pharmacologic Substance ;
=Pregnadienes; Steroids, Fluorinated; FLUOCINOLONE; =(6alpha,11beta,16alpha)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione; FLUNISOLIDE; FLUOCINOLONE ACETONIDE PWDR,TOP; FLUOCINOLONE ACETONIDE 0.2 %; FLUOCINOLONE ACETONIDE 0.01 %; FLUOCINOLONE ACETONIDE 0.025 %; FLUOCINOLONE ACETONIDE 0.1 % | - 89. 18a
- [Mandibular left second molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553652) =Medical Device =Artificial dentition;
|
- 40. (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid, S-(Fluoromethyl) Ester
- [The propionate salt form of fluticasone, a synthetic trifluorinated glucocorticoid receptor agonist with antiallergic, antiinflammatory and antipruritic effects. Binding and activation of the glucocorticoid receptor results in the activation of lipocortin that in turn inhibits cytosolic phospholipase A2, which triggers cascade of reactions involved in synthesis of inflammatory mediators, such as prostaglandins and leukotrienes. Secondly, mitogen-activated protein kinase (MAPK) phosphatase 1 is induced, thereby leads to dephosphorylation and inactivation of Jun N-terminal kinase directly inhibiting c-Jun mediated transcription. Finally, transcriptional activity of nuclear factor (NF)-kappa-B is blocked, thereby inhibits the transcription of cyclooxygenase 2, which is essential for prostaglandin production. ( NCI )] (UMLS (NCI) C0117996) =Organic Chemical; Pharmacologic Substance =FLUTICASONE;
=FLUTICASONE PROPIONATE 50 MCG; FLUTICASONE PROPIONATE 500 MCG; FLUTICASONE PROPIONATE 50 MCG/ACTUAT; FLUTICASONE PROPIONATE 0.05 %; FLUTICASONE PROPIONATE 110 MCG/ACTUAT; FLUTICASONE PROPIONATE 44 MCG/ACTUAT; FLUTICASONE PROPIONATE 220 MCG/ACTUAT; FLUTICASONE PROPIONATE 250 MCG; FLUTICASONE PROPIONATE 100 MCG; FLUTICASONE PROPIONATE 0.005 % | - 90. 18ad
- [Mandibular left second molar abutment distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1553654) =Medical Device =Artificial dentition;
|
- 41. (7alpha,11beta,16alpha)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione
- [The dipropionate salt form of alclometasone, a synthetic corticosteroid with low to medium potency. Alclometasone dipropionate is a glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, immunosuppressive, antipruritic, and vasoconstrictive effects of natural glucocorticoids. This drug interacts with specific intracellular receptors and binds to DNA to modify gene expression. This results in an induction of synthesis of certain proteins while inhibiting the synthesis of others. Alclometasone dipropionate is used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. (NCI05) ( NCI )] (UMLS (NCI) C0051113) =Steroid; Pharmacologic Substance ;
=(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione; ALCLOMETASONE =ALCLOMETASONE DIPROPIONATE 0.05 %; | - 91. 18am
- [Mandibular left second molar abutment mesial hemisection ( HL7V3.0 )] (UMLS (HL7) C1553653) =Medical Device =Artificial dentition;
|
- 42. (7aS-cis)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one
- (UMLS (NCI) C0664750) =Organic Chemical; Pharmacologic Substance ;
| - 92. 19a
- [Mandibular left first molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553655) =Medical Device =Artificial dentition;
|
- 43. (9alpha,10beta,11beta,13alpha)-(+)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H-9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
- [exhibits cytotoxic or antitumor properties; naturally derived from cultures of Streptomyces; inhibits protein kinase C. ( CSP )] (UMLS (NCI) C0075193) =Organic Chemical; Pharmacologic Substance ;
=alkaloid; | - 93. 19ad
- [Mandibular left first molar abutment distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1553657) =Medical Device =Artificial dentition;
|
- 44. (aa Beta, 17 beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
- [11-((4-dimethylamino) phenyl)-17-hydroxy-17-(1-propynyl) estra-4,9- dien-3-one; progesterone and glucocorticoid antagonist with potential applications in terminating pregnancy, controlling menstruation, and treating hypercortisolism. ( CSP )] (UMLS (NCI) C0026088) =Steroid; Pharmacologic Substance ;
=abortifacient; Estrenes; hormone antagonist; [HS200] CONTRACEPTIVES, SYSTEMIC =MIFEPRISTONE 200 MG; | - 94. 19am
- [Mandibular left first molar abutment mesial hemisection ( HL7V3.0 )] (UMLS (HL7) C1553656) =Medical Device =Artificial dentition;
|
- 45. (All-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid
- [A naturally-occurring acid of retinol. Tretinoin binds to and activates retinoic acid receptors (RARs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, and inhibition of tumorigenesis. This agent also inhibits telomerase, resulting in telomere shortening and eventual apoptosis of some tumor cell types. The oral form of tretinoin has teratogenic and embryotoxic properties. ( NCI )] (UMLS (NCI) C0040845) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
[VT050] VITAMIN A; [DE752] ANTIACNE AGENTS, TOPICAL; =3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-trans-4-trans-6-cis-8-trans-nonatetraenoic Acid; TRETINOIN 10 MG; TRETINOIN PWDR; TRETINOIN 0.05 %; TRETINOIN 0.1 %; TRETINOIN 0.01 %; TRETINOIN 0.025 %; TRETINOIN 0.04 %; | - 95. 1a
- [Maxillary right third molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553633) =Medical Device =Artificial dentition;
|
- 46. (All-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid
- [A drug used in cancer prevention that belongs to the family of drugs called retinoids. It is also used in the treatment of psoriasis. ( NCI )] (UMLS (NCI) C0050559) =Organic Chemical; Pharmacologic Substance ;
=Retinoic Acid Agent; [DE801] ANTIPSORIATICS, SYSTEMIC =ACITRETIN 10 MG; ACITRETIN 25 MG | - 96. 1alphaH,5alphaH-Tropan-3alpha-ol, 6beta,7beta-epoxy-,(-)-tropate(ester)
- [anticholinergic alkaloid. ( CSP )] (UMLS (NCI) C0036442) =Organic Chemical; Pharmacologic Substance =alkaloid;
Belladonna Alkaloids; 1alphaH,5alphaH-Tropan-3alpha-ol, 6beta,7beta-epoxy-,(-)-tropate(ester); tropane; Anticholinergic Agent; [CN550] ANTIVERTIGO AGENTS =1alphaH,5alphaH-Tropan-3alpha-ol, 6beta,7beta-epoxy-,(-)-tropate(ester); Scopolamine Derivatives; HYOSCINE HYDROBROMIDE; SCOPOLAMINE 0.33 MG |
- 47. (all-Z)-5,8,11,14-Eicosatetraenoic Acid
- [An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.(ChemID Plus) ( NCI )] (UMLS (NCI) C0003695) =Eicosanoid ;
| - 97. 1alphaH,5alphaH-Tropanium, 6beta,7beta-epoxy-3alpha-hydroxy-8-methyl-, bromide,(-)-tropate(8CI)
- [The bromide salt form of methscopolamine, a quaternary ammonium derivative of scopolamine with anticholinergic properties. Methscopolamine bromide exerts its effect on muscarine receptors in the gastrointestinal tract, thereby blocking the actions of acetylcholine. This leads to an inhibition of gastric secretions and gastrointestinal motility. ( NCI )] (UMLS (NCI) C0141756) =Organic Chemical; Pharmacologic Substance =METHSCOPOLAMINE;
=METHSCOPOLAMINE BROMIDE 2.5 MG |
- 48. (Aorto)coronary bypass of four or more coronary arteries
- [ ] (UMLS (ICD9CM) C0190236) =Therapeutic or Preventive Procedure
| - 98. 2 Alpha-Methyldihydrotestosterone Propionate
- [The propionate salt form of dromostanolone, a synthetic anabolic steroid related to dihydrotestosterone that has antiestrogenic effects. Dromostanolone inhibits the growth of estrogen receptor-presenting breast cancers; its virilizing effects limit its clinical usefulness. (NCI) ( NCI )] (UMLS (NCI) C0058758) =Steroid; Pharmacologic Substance
|
- 49. (Aorto)coronary bypass of one coronary artery
- [ ] (UMLS (ICD9CM) C0190224) =Therapeutic or Preventive Procedure
| - 99. 2 amino 4 phosphonobutyrate
- [ ] (UMLS (CSP) C0206979) =Organic Chemical; Pharmacologic Substance ;
|
- 50. (Aorto)coronary bypass of three coronary arteries
- [ ] (UMLS (ICD9CM) C0190232) =Therapeutic or Preventive Procedure
| - 100. 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium Chloride
- [slowly hydrolyzed cholinergic agonist that acts at both muscarinic and nicotinic receptors. ( CSP )] (UMLS (NCI) C0006945) =Organic Chemical; Pharmacologic Substance =choline;
cholinergic agent; [OP102] MIOTICS, TOPICAL OPHTHALMIC; [OP109] ANTIGLAUCOMA, OTHER =CARBACHOL 0.75 %WV; CARBACHOL 1.5 %; CARBACHOL 2.25 %; CARBACHOL 3 %; CARBACHOL 0.01 % |