- 2201. A-65
- [An amide analogue of Trichostatin A studied for potential antineoplastic activity. A-65 inhibits zinc-dependent histone deacetylase, inducing terminal cell differentiation and anti-angiogenic activity. (NCI04) ( NCI )] (UMLS (NCI) C1510673) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 2251. AA
- [Island in the Caribbean Sea, north of Venezuela. (NCI) ( NCI )] (UMLS (NCI) C0282379) =Geographic Area
|
- 2202. A-85761
- (UMLS (NCI) C0384232) =Organic Chemical; Pharmacologic Substance ;
| - 2252. AAA
- [Encoded by human APP Gene (APP Family), Amyloid Beta A4 Protein Precursor is an N-/O-glycosylated sulfated metal ion-binding type I cell surface protein containing a BPTI protease inhibitor domain. Widely expressed APP is processed by secretases into soluble peptides, membrane-anchored fragments, plaque amyloid components, and cytotoxic fragments. Phosphorylation by Casein Kinases, CDC5, CDC2, and MAPK10 can affect processing, interaction with Fe65, and SHC binding. A kinesin I membrane receptor for cell mobility, adhesion, and axonogenesis/synaptogenesis, APP variants inhibit Notch signaling, regulate copper homeostasis, bind lipoproteins, activate transcription, and enhance apoptosis via G(O) and JIP pathways. NPXY is required for binding protein PID domains, endocytosis, and BaSS sorting. APP defects cause Alzheimer's disease and cerebroarterial amyloidosis. ( NCI )] (UMLS (NCI) C0611285) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 2203. A-DNA
- [A-DNA is a shorter and wider helix than B-DNA. Most RNA and RNA-DNA duplex are in this form. While deep, narrow major groove is not easily accessible to proteins but wide, shallow minor groove is accessible to proteins but with lower information content than major groove. A-DNA is the favored conformation at low water concentrations. Base pairs are tilted to helix axis and displaced from axis and sugar pucker is C3'-endo (in RNA 2'-OH inhibits C2'-endo conformation). When examined from the top of the helix, there is a large hole in the middle, the sugar phosphate backbone is at the edge of the helix, and the bases are displaced towards the edge. ( NCI )] (UMLS (NCI) C0000702) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance
| - 2253. AAF
- [hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the arylhydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide; used to study the carcinogenicity and mutagenicity of aromatic amines. ( CSP )] (UMLS (CSP) C0001034) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 2204. A-Esterase
- [Acts on many phenolic esters. The reactions of EC 3.1.8.1 aryldialkylphosphatase, were previously attributed to this enzyme. [EC 3.1.1.2 created 1961, modified 1989] (from IUBMB Enzyme Nomenclature). ( NCI )] (UMLS (NCI) C0052451) =Amino Acid, Peptide, or Protein; Enzyme
| - 2254. AAFC
- [A Cytosine Arabinoside derivative that inhibits pyrimidine synthesis, causing inhibition of DNA synthesis. (NCI) ( NCI )] (UMLS (NCI) C0049176) =Organic Chemical; Pharmacologic Substance ;
|
- 2205. A-MethaPred
- (UMLS (NCI) C0701467) =Steroid; Pharmacologic Substance; Hormone
| - 2255. Aagenaes Syndrome
- (UMLS (NCI) C0268314) =Disease or Syndrome ;
|
- 2206. A-Microtubule
- (UMLS (NCI) C1510674) =Cell Component ;
| - 2256. AAT
- (UMLS (NCI) C0052586) =Therapeutic or Preventive Procedure ;
|
- 2207. A-myb Messenger RNA Overexpression
- (UMLS (NCI) C1510675) A-myb mRNA Overexpression;
=Cell or Molecular Dysfunction ;
| - 2257. AAT1
- [Expressed in liver, kidney, heart, fat, and skeletal muscle by glucocorticoid-induced human GPT Gene (Alanine Aminotransferase Family), 495-aa 54-kDa Glutamic-Pyruvate Transaminase is a homodimeric cytoplasmic pyridoxal phosphate-dependent enzyme involved in cellular nitrogen metabolism, amino acid metabolism, and liver gluconeogenesis. GPT mediates conversion of major intermediate metabolites, catalyzing reversible transamination between alanine and alpha-ketoglutarate to form pyruvate and glutamate. (NCI) ( NCI )] (UMLS (NCI) C0001899) =Amino Acid, Peptide, or Protein; Enzyme
|
- 2208. a-protein
- [HMGA1a is one of three protein products of the same gene, HMGA1, generated by alternative splicing. The HMGA1a protein contains three basic domains, named AT-hooks and an acidic C-terminal region. AT-hooks are responsible for binding to AT-rich sequences inside the minor groove of DNA. Phosphorylation of HMGA1a by both PKC and cdc-2 kinases strongly reduces its DNA binding affinity and is critical in cell cycle progression. HMGA1a activates the interferon-beta gene (IFN-beta) by functioning as the essential architectural component for the assembly and stability of the IFN-beta enhanceosome. (PMID11576996) ( NCI )] (UMLS (NCI) C0038164) =Amino Acid, Peptide, or Protein; Immunologic Factor; Indicator, Reagent, or Diagnostic Aid
| - 2258. AAV2
- [This strain of viridae is a non-pathogenic human parvovirus that is icosahedral, 20-25 nm in diameter, minus sense, and comprised of a 5 kb. single-stranded DNA genome. The virus is generally monomorphic and has been developed as a gene therapy vector for the treatment of numerous diseases. Wild-type AA-2 retains the ability to preferentially integrate its DNA into a 4 kilobase region of human chromosome 19, designated AAVS1, making it an attractive gene therapy vehicle. The virus has demonstrated anti-cancer activity by inducing apoptosis and inhibiting the growth of cancer cells. ( NCI )] (UMLS (NCI) C0319124) =Virus
|
- 2209. A-RAF Protein Kinase
- [Encoded by human ARAF1 Gene (MIL/RAF Family), cytoplasmic A-RAF [serine/threonine] Protein Kinase contains a DAG binding and a RBD domain, and is involved in transduction of mitogenic signals from cell membrane to nucleus. ( NCI )] (UMLS (NCI) C0100762) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 2259. Ab
- [infection-fighting protein molecule in blood or secretory fluids that tags, neutralizes, and helps destroy pathogenic microorganisms such as bacteria or viruses and toxins; they are generally known as immunoglobulins, and are made and secreted by B-lymphocytes in response to stimulation by antigens; each specific antibody binds only to the specific antigen that stimulated its production. ( CSP )] (UMLS (NCI) C0003241) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 2210. A/He Mouse
- (UMLS (NCI) C1510706) =Mammal ;
| - 2260. AB FINDINGS-BREAST NEC
- [ ] (UMLS (ICD9CM) C0949148) Other abnormal findings on radiological examination of breast =Disease or Syndrome
|
- 2211. A/HeJ
- (UMLS (NCI) C1510705) A/HeJ Mouse;
=Mammal ;
| - 2261. AB FTL HRT RT/RH B/F LAB
- [ ] (UMLS (ICD9CM) C0695249) =Pathologic Function
|
- 2212. A/J
- (UMLS (NCI) C1510707) A/J Mouse;
=Mammal ;
| - 2262. AB FTL HRT RT/RH DUR LAB
- [ ] (UMLS (ICD9CM) C0695250) =Pathologic Function
|
- 2213. A/JOlaHsd
- (UMLS (NCI) C1510708) A/JOlaHsd Mouse;
=Mammal ;
| - 2263. AB FTL HRT RT/RHY NOS
- [ ] (UMLS (ICD9CM) C0695251) =Pathologic Function
|
- 2214. A/WySnJ
- (UMLS (NCI) C1510709) A/WySnJ Mouse;
=Mammal ;
| - 2264. AB MAMMOGRAM NOS
- [ ] (UMLS (ICD9CM) C0949146) Abnormal mammogram, unspecified =Disease or Syndrome
|
- 2215. A01, A04, A08, A13
- (UMLS (HL7) C1548674) =Intellectual Product =Message structure;
| - 2265. AB NOS UNCOMPLICAT-COMP
- [ ] (UMLS (ICD9CM) C0156582) =Injury or Poisoning
|
- 2216. A02
- (UMLS (HL7) C1548675) =Intellectual Product =Message structure;
| - 2266. AB NOS UNCOMPLICAT-INC
- [ ] (UMLS (ICD9CM) C0156581) =Injury or Poisoning
|
- 2217. A03
- (UMLS (HL7) C1548676) =Intellectual Product =Message structure;
| - 2267. AB NOS UNCOMPLICAT-UNSP
- [ ] (UMLS (ICD9CM) C0156580) =Pathologic Function
|
- 2218. A05, A14, A28, A31
- (UMLS (HL7) C1548677) =Intellectual Product =Message structure;
| - 2268. AB NOS W COMPL NEC-COMP
- [ ] (UMLS (ICD9CM) C0156575) =Pathologic Function
|
- 2219. A06, A07
- (UMLS (HL7) C1548678) =Intellectual Product =Message structure;
| - 2269. AB NOS W COMPL NEC-INC
- [ ] (UMLS (ICD9CM) C0156574) =Pathologic Function
|
- 2220. A09, A10, A11, A12
- (UMLS (HL7) C1548679) =Intellectual Product =Message structure;
| - 2270. AB NOS W COMPL NEC-UNSP
- [ ] (UMLS (ICD9CM) C0156573) =Injury or Poisoning
|
- 2221. A10/AS2-1
- (UMLS (NCI) C0281644) =Therapeutic or Preventive Procedure
| - 2271. AB NOS W COMPL NOS-COMP
- [ ] (UMLS (ICD9CM) C0156579) =Pathologic Function
|
- 2222. A10/MTX
- (UMLS (NCI) C0796429) Antineoplaston A10/Methotrexate =Therapeutic or Preventive Procedure
| - 2272. AB NOS W COMPL NOS-INC
- [ ] (UMLS (ICD9CM) C0156578) =Pathologic Function
|
- 2223. A15
- (UMLS (HL7) C1548680) =Intellectual Product =Message structure;
| - 2273. AB NOS W COMPL NOS-UNSP
- (UMLS (ICD9CM) C1299558) Unspecified abortion with unspecified complication;
Unspecified type of abortion, unspecified, with unspecified complication =Pathologic Function |
- 2224. A16
- (UMLS (HL7) C1548681) =Intellectual Product =Message structure;
| - 2274. AB NOS W EMBOLISM-COMP
- [ ] (UMLS (ICD9CM) C0156571) =Injury or Poisoning
|
- 2225. A17
- (UMLS (HL7) C1548682) =Intellectual Product =Message structure;
| - 2275. AB NOS W EMBOLISM-INC
- [ ] (UMLS (ICD9CM) C0156570) =Disease or Syndrome
|
- 2226. A18
- (UMLS (HL7) C1548683) =Intellectual Product =Message structure;
| - 2276. AB NOS W EMBOLISM-UNSP
- [ ] (UMLS (ICD9CM) C0156568) =Disease or Syndrome
|
- 2227. A19
- (UMLS (HL7) C1549870) =Intellectual Product =Message structure;
| - 2277. AB NOS W METAB DIS-COMP
- [ ] (UMLS (ICD9CM) C0156563) =Injury or Poisoning
|
- 2228. A1G4 anti-idiotype monoclonal antibody vaccine
- [An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune responses against GD2 expression tumor cells. ( NCI )] (UMLS (NCI) C0677670) =Pharmacologic Substance; Immunologic Factor ;
| - 2278. AB NOS W METAB DIS-INC
- [ ] (UMLS (ICD9CM) C0156562) =Injury or Poisoning
|
- 2229. A20
- (UMLS (HL7) C1548684) =Intellectual Product =Message structure;
| - 2279. AB NOS W METAB DIS-UNSP
- [ ] (UMLS (ICD9CM) C0156561) =Injury or Poisoning
|
- 2230. A21, A22, A23, A25, A26, A27, A29, A32, A33
- (UMLS (HL7) C1548685) =Intellectual Product =Message structure;
| - 2280. AB NOS W PELV DAMAG-COMP
- [ ] (UMLS (ICD9CM) C0156555) =Injury or Poisoning
|
- 2231. A24
- (UMLS (HL7) C1548686) =Intellectual Product =Message structure;
| - 2281. AB NOS W PELV DAMAG-INC
- [ ] (UMLS (ICD9CM) C0156554) =Injury or Poisoning
|
- 2232. A27.15
- [A murine IgG1 monoclonal antibody directed against the human transferrin (Tf) receptor. Monoclonal antibody A27.15 binds to the Tf receptor, blocking the binding of transferrin to the receptor and resulting in decreased tumor cell growth. (NCI04) ( NCI )] (UMLS (NCI) C0677772) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 2282. AB NOS W PELV DAMAG-UNSP
- [ ] (UMLS (ICD9CM) C1263817) Unspecified abortion complicated by damage to pelvic organs or tissues;
Unspecified type of abortion, unspecified, complicated by damage to pelvic organs or tissues;
=Injury or Poisoning |
- 2233. A28807, Rat Strain
- [Very docile. Susceptible to the induction of autoimmune thyroiditis. Low and intermediate antibody responses to 1 and 10 g BSA, respectively. Low antibody response to streptococcal group A carbohydrate; not linked to the MHC. High relative heart weight in 10-week old males (20/23). ( NCI )] (UMLS (NCI) C1510676) =Mammal ;
| - 2283. AB NOS W RENAL FAIL-COMP
- [ ] (UMLS (ICD9CM) C0156559) =Injury or Poisoning
|
- 2234. A2G Mouse
- (UMLS (NCI) C1510677) =Mammal ;
| - 2284. AB NOS W RENAL FAIL-INC
- [ ] (UMLS (ICD9CM) C0156558) =Injury or Poisoning
|
- 2235. A30, A34, A35, A36, A46, A47, A48, A49
- (UMLS (HL7) C1548687) =Intellectual Product =Message structure;
| - 2285. AB NOS W RENAL FAIL-UNSP
- [ ] (UMLS (ICD9CM) C0156556) =Disease or Syndrome
|
- 2236. A32
- [Active in neural crest cells during development and expressed primarily in neuroectodermal lineages and vascular smooth muscle in adult tissues by human MCAM Gene (Ig Superfamily), 646-aa 72-kDa (precursor) Melanoma Adhesion Molecule is a cell surface type I membrane glycoprotein containing 3 Ig-like C2-type domains and 2 Ig-like V-type domains and a possible adhesion molecule homologue of cell adhesion molecule NCAM. (NCI) ( NCI )] (UMLS (NCI) C0386212) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
| - 2286. AB-DIC
- (UMLS (NCI) C0081426) =Therapeutic or Preventive Procedure ;
|
- 2237. A33
- [A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells. ( NCI )] (UMLS (NCI) C0392959) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 2287. Abacavir
- [A synthetic carbocyclic nucleoside analog. In vivo, the activated triphosphate metabolite of abacavir is incorporated into the viral DNA instead of the natural substrate deoxyguanosine, thereby inhibiting human immunodeficiency virus (HIV) reverse transcriptase (RT) and, so, the replication of the viral DNA and infectious viral particles. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS. ( NCI )] (UMLS (NCI) C0663655) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM800] ANTIVIRALS;
deoxyribonucleoside;
Reverse Transcriptase Inhibitor;
1592U89 =Abacavir Sulfate;
|
- 2238. A37
- (UMLS (HL7) C1548688) =Intellectual Product =Message structure;
| - 2288. Abacavir Sulfate
- [The sulfate salt form of abacavir, a synthetic carbocyclic nucleoside analog. In vivo, the activated triphosphate metabolite of abacavir is incorporated into the viral DNA instead of the natural substrate deoxyguanosine, thereby inhibiting human immunodeficiency virus (HIV) reverse transcriptase (RT) and, so, the replication of the viral DNA and infectious viral particles. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS. ( NCI )] (UMLS (NCI) C0724515) ABACAVIR SULFATE PREPARATION;
=Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=Abacavir;
=ABACAVIR SULFATE 100 MG/5ML;
ABACAVIR SULFATE 300 MG;
|
- 2239. A38
- (UMLS (HL7) C1548689) =Intellectual Product =Message structure;
| - 2289. Abagovomab
- [A murine immunoglobulin G1 (IgG1) monoclonal anti-idiotype antibody (ACA125). Vaccination with abagovomab may stimulate the host immune system to mount an antibody response and subsequent antibody-dependent cell-mediated cytotoxicity response against CA125 positive tumor cells, thereby decreasing tumor growth. (NCI04) ( NCI )] (UMLS (NCI) C1327946) Monoclonal Antibody ACA125 Anti-Idiotype Vaccine =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 2240. A39, A40, A41, A42
- (UMLS (HL7) C1548690) =Intellectual Product =Message structure;
| - 2290. abalone
- [ ] (UMLS (CSP) C0598488) =Invertebrate ;
|
- 2241. A3AR
- [Widely expressed by human ADORA3 Gene (GPCR1 Family), 318-aa 36-kDa Adenosine A3 Receptor is a cell-surface integral membrane protein containing 7 transmembrane domains and 3 potential N-glycosylation sites that interacts with a heterotrimeric G protein complex in response to adenosine ligand to suppress cAMP accumulation through adenylate cyclase inhibition. ADORA3 exhibits about 71% homology with A3ar (rat). Released during ischemia, adenosine exerts a potent protective effect through ADORA3 on cardiac ventricular cells. ADORA3 may have a role in reproduction. ( NCI )] (UMLS (NCI) C0664494) =Amino Acid, Peptide, or Protein; Receptor ;
| - 2291. Abandonment or neglect of infants and helpless persons
- [ ] (UMLS (ICD9CM) C0261659) =Human-caused Phenomenon or Process
|
- 2242. A43, A44
- (UMLS (HL7) C1548691) =Intellectual Product =Message structure;
| - 2292. Abasic Site Formation
- [Abasic Site Formation involves the creation of an apurinic or apyrimidinic site resulting from the loss of a purine or pyrimidine residue from DNA. ( NCI )] (UMLS (NCI) C1510710) Formation of Abasic Site;
=Cell or Molecular Dysfunction |
- 2243. A45
- (UMLS (HL7) C1548692) =Intellectual Product =Message structure;
| - 2293. Abatement of event after product withdrawn
- (UMLS (HL7) C1546994) =Idea or Concept =Causality Observations;
|
- 2244. A50, A51
- (UMLS (HL7) C1548693) =Intellectual Product =Message structure;
| - 2294. Abbokinase
- (UMLS (NCI) C0701941) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Enzyme ;
|
- 2245. A52, A53, A55
- (UMLS (HL7) C1548694) =Intellectual Product =Message structure;
| - 2295. Abbott 40566
- (UMLS (NCI) C0740167) =Organic Chemical; Pharmacologic Substance ;
|
- 2246. A54
- (UMLS (HL7) C1548695) =Intellectual Product =Message structure;
| - 2296. Abbott Laboratories
- (UMLS (HL7) C1546858) =Health Care Related Organization =Manufacturers of Vaccines (code=MVX);
|
- 2247. A60
- (UMLS (HL7) C1548696) =Intellectual Product =Message structure;
| - 2297. Abbott Laboratories (includes Ross Products Division)
- [Abbott Laboratories (includes Ross Products Division) ( HL7V3.0 )] (UMLS (HL7) C1552881) =Health Care Related Organization =VaccineManufacturer;
|
- 2248. A61, A62
- (UMLS (HL7) C1548697) =Intellectual Product =Message structure;
| - 2298. Abbott-56268
- (UMLS (NCI) C0701282) =Organic Chemical; Antibiotic
|
- 2249. A990, Rat Strain
- [Resistant to Cysticercus. Susceptible to estrogen-induced mammary and adrenal tumors. Good reproduction. High open-field defecation (2/12, males, 3/12 females) and low ambulation (11/12), Harrington (1972). Low wheel activity (12/12) (Harrington 1971b). Aggressive towards handlers (Harrington 1981). ( NCI )] (UMLS (NCI) C1510678) =Mammal ;
| - 2299. ABBP-1
- [Heterogeneous Nuclear Ribonucleoprotein A/B, encoded by the HNRPAB gene, belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and they form a component of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It acts as the catalytic component of the multiprotein editosome complex which mediates apolipoprotein B mRNA editing. Two alternatively spliced transcript variants has been described for this gene which encode different isoforms. (from LocusLink) ( NCI )] (UMLS (NCI) C0534522) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 2250. aa
- [organic acid containing one or more amino groups, especially any of a group that make up proteins and are important to living cells; those that are nonessential can be synthesized by the body while essential acids must be obtained through the diet; there are also several important amino acids, such as the neurotransmitter g-aminobutyric acid, that have no relation to proteins. ( CSP )] (UMLS (NCI) C0002520) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance
| - 2300. Abbreviation
- [A shortened form of a word or phrase. ( NCI )] (UMLS (NCI) C0000723) =Intellectual Product ;
|
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