- 1701. 4-Aminobenzenesulfonamide
- [potent antibacterial agent, the first of the sulfonamides discovered. ( CSP )] (UMLS (NCI) C0038702) =Organic Chemical; Antibiotic =Sulfanilamides;
benzenesulfonamide;
antibacterial agent;
[GU300] ANTI-INFECTIVES, VAGINAL =Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-;
SULFANILAMIDE 1.05 GM;
SULFANILAMIDE 15 %;
| - 1751. 40-49% BDY BRN/30-39% 3D
- [ ] (UMLS (ICD9CM) C0161345) =Injury or Poisoning
|
- 1702. 4-Aminofolic acid
- [folic acid derivative used as a rodenticide that has been shown to be teratogenic. ( CSP )] (UMLS (NCI) C0002583) =Organic Chemical; Hazardous or Poisonous Substance
| - 1752. 40-49% BDY BRN/40-49% 3D
- [ ] (UMLS (ICD9CM) C0161346) =Injury or Poisoning
|
- 1703. 4-Androstene-3,17-dione
- [delta-4 C19 steroid that is produced in the testes, ovaries and adrenal cortex and can serve as a precursor to testosterone as well as estrone and estradiol. ( CSP )] (UMLS (NCI) C0002860) =Steroid; Pharmacologic Substance; Hormone
| - 1753. 40083
- [Encoded by human IFITM1 Gene (IFN-Induced Transmembrane Protein Family), 125-amino acid 14-kD Interferon-Induced Transmembrane Protein 1 is an IFN-alpha- and -gamma-inducible membrane protein subunit of a multimeric complex involved in antiproliferative and homotypic adhesion signal transduction. IFITM1 Protein appears to demarcate germ cells from somatic neighbors and to mark the onset of germ cell competence. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1312248) CD225 Antigen;
Fragilis Homolog;
IFI17;
IFITM1;
IFITM1 Protein;
Interferon-Induced Protein 17;
Interferon-Induced Transmembrane Protein 1;
Interferon-Inducible Protein 9-27;
Interferon-Inducible Transmembrane Protein 11;
LEU13;
LEU-13 Antigen =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 1704. 4-carboxyphenyl retinamide
- [A synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Carboxyphenyl retinamide induces cell differentiation and inhibits tumor cell growth and carcinogenesis. This agent may also induce cell cycle arrest in the G1 phase in some cancer cell types. (NCI04) ( NCI )] (UMLS (NCI) C0067533) =Organic Chemical; Pharmacologic Substance
| - 1754. 40148
- [Encoded by human DEC1 Gene, widely expressed 70-amino acid DEC1 Protein is a candidate tumor suppressor protein of unknown function; possibly negative regulation of cell proliferation. (from LocusLink, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0664219) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 1705. 4-Chloroamphetamine
- [Chlorinated analog of AMPHETAMINE. Potent neurotoxin that causes release and eventually depletion of serotonin in the CNS. It is used as a research tool. ( MSH )] (UMLS (NCI) C0030131) =Organic Chemical; Pharmacologic Substance ;
| - 1755. 40148
- [This gene may play a role in tumor suppression. ( NCI )] (UMLS (NCI) C1333212) DEC1 Gene;
Deleted in Esophageal Cancer 1 Gene =Gene or Genome ;
|
- 1706. 4-dedimethylamino sancycline
- [An anticancer drug that may stop tumor growth by preventing the growth of new blood vessels into a solid tumor. ( NCI )] (UMLS (NCI) C0763138) 4-Dimethlyamino Sancycline;
4-Dimethlyaminosancycline;
6-deoxy, 6-demethyl, 4-de-dimethylamino tetracycline;
6-deoxy-6-demethyl-4-dedimethylaminotetracycline;
CMT-3;
COL 3;
COL-3 =Organic Chemical; Pharmacologic Substance | - 1756. 40S Ribosomal Protein S19
- [Encoded by human RPS19 Gene (S19E Family), 144-aa 16-kDa cytoplasmic Ribosomal Protein S19 is a component of the 40S ribosomal subunit. S19 lacks cysteine residues and has a possible function in erythropoietic differentiation and proliferation. Composed of small 40S and large 60S subunits containing 4 rRNAs and approximately 80 proteins, ribosomes catalyze protein synthesis. (NCI) ( NCI )] (UMLS (NCI) C0073320) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 1707. 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
- [A tertiary amine possessing antimuscarinic and antispasmodic properties. Oxybutynin blocks muscarinic receptors in smooth muscle, hence inhibiting acetylcholine binding and subsequent reduction of involuntary muscle contractions. Oxybutynin is used to reduce bladder contractions by relaxing bladder smooth muscle. ( NCI )] (UMLS (NCI) C0069805) =Organic Chemical; Pharmacologic Substance ;
=Mandelic Acids;
[GU201] ANTISPASMODICS, URINARY =OXYBUTYNIN CHLORIDE;
OXYBUTYNIN 3.9 MG;
| - 1757. 40s Ribosomal Protein S27
- [Expressed in actively proliferating cells by human RPS27 Gene (S27E Family), 83-aa 9-kDa Ribosomal Protein S27 is located in the cytoplasm as a component of the 40S ribosomal subunit, but is also detected in the nucleus. Composed of small 40S and large 60S subunits containing 4 rRNAs and approximately 80 proteins, ribosomes catalyze protein synthesis. S27 appears to be located near ribosomal protein S18 and to be covalently linked to translation initiation factor eIF3. S27 contains a C4-type zinc finger domain and is able to bind to nucleic acid. (NCI) ( NCI )] (UMLS (NCI) C0527863) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 1708. 4-Dimethylaminoazobenzene
- [A yellow, crystalline solid compound. 4-Dimethylaminoazobenzene was used as a dye for coloring polishes, wax products, polystyrene and soap, and was also used as a pH indicator, but is no longer used or produced in the United States. Exposure to this substance causes dermatitis. 4-dimethylaminoazobenzene is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0012411) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 1758. 40S Ribosomal Protein S3
- [Encoded by human RPS3 Gene (S3P Family), cytoplasmic and nuclear 243-aa 27-kDa Ribosomal Protein S3 contains a KH type-2 domain and is a component of the 40S ribosomal subunit as part of the translation initiation domain. Composed of small 40S and large 60S subunits containing 4 rRNAs and approximately 80 proteins, ribosomes catalyze protein synthesis. RPS3 also appears to be an endonuclease involved in UV-induced DNA repair. (NCI) ( NCI )] (UMLS (NCI) C0073328) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 1709. 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic Acid
- [A sialic acid analog and a neuraminidase inhibitor with antiviral property. Zanamivir selectively inhibits influenza A and B virus neuraminidase, a viral surface glycoprotein, which mediates the cleavages of sialic acid residues on the surfaces of host cells and influenza viral envelopes. The uncleaved sialic acid residues were bound by viral hemagglutinin, thereby resulting in viral aggregation at the host cell surface, thereby preventing the release of influenza virus particles into the respiratory tract. ( NCI )] (UMLS (NCI) C0216660) =Organic Chemical; Pharmacologic Substance ;
=[AM800] ANTIVIRALS;
Sialic Acids =ZANAMIVIR 5 MG | - 1759. 46XX
- [The normal genotype of a female human. ( NCI )] (UMLS (NCI) C0450371) =Organism Attribute ;
|
- 1710. 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-
- [antibiotic substance derived from Penicillium stoloniferum and related species which blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase; mycophenolic acid has selective effects on the immune system, preventing the proliferation of T cells, lymphocytes, and the formation of antibodies from B cells. ( CSP )] (UMLS (NCI) C0026933) =Lipid; Antibiotic =antineoplastic antibiotics;
benzofuran;
Caproates;
=RS 61443 | - 1760. 4a
- [Maxillary right second premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553636) =Medical Device =Artificial dentition;
|
- 1711. 4-Hexylresorcinol
- [A substituted phenol with bactericidal, antihelminthic and potential antineoplastic activities. Hexylresorcinol is used as an antiseptic in mouthwashes and skin wound cleansers. Hexylresorcinol may also inhibit oxidative DNA damage by enhancing the activity of antioxidant enzymes, including glutathione peroxidase and glutathione reductase, which facilitate scavenging reactive oxygen molecules by glutathione (GSH). ( NCI )] (UMLS (NCI) C0019497) =Organic Chemical; Pharmacologic Substance
| - 1761. 4B5 monoclonal antibody anti-idiotype vaccine
- [A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id 4B5 IgG was capable of eliciting both cellular and humoral immune responses against GD2 expression tumor cells. ( NCI )] (UMLS (NCI) C0879386) MoAb 4B5 anti-idiotype vaccine;
Monoclonal Antibody 4B5 Anti-Idiotype Vaccine =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 1712. 4-HYDROXY BUTYRIC ACID
- [A naturally occurring short-chain fatty acid, and immediate precursor of gamma amino butyric acid (GABA) with neuromodulatory and anesthetic properties. Gamma-Hydroxybutyric Acid (GHB) is found in all human tissues, with the highest concentration in the brain. This agent stimulates the GHB receptor, and to a lesser extent GABA-B receptors. Although, the precise function and metabolic pathways of GHB are not fully understood, this agent easily crosses the blood-brain barrier, and affects the activities and levels of dopamine, acetylcholine, dynorphin and serotonin. The primary effect of GHB is central nervous system depression, thereby, its main usage is to induce anesthesia. ( NCI )] (UMLS (NCI) C0673093) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance
| - 1762. 4H-1-benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-8-methoxy-
- (UMLS (NCI) C0072562) =Organic Chemical
|
- 1713. 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
- [An oxicam derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Unlike traditional nonselective NSAIDs, meloxicam preferentially inhibits the activity of cyclo-oxygenase II (COX-II), resulting in a decreased conversion of arachidonic acid into prostaglandin precursors. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of meloxicam. ( NCI )] (UMLS (NCI) C0083381) =Organic Chemical; Pharmacologic Substance =thiazine;
thiazole;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;
=MELOXICAM 7.5 MG;
MELOXICAM 15 MG;
| - 1763. 4H-1-benzopyran-8-acetic Acid, 4-Oxo-2-phenyl
- [A synthetic flavonoid with vascular targeting properties. Flavone acetic acid exhibits an antiproliferative effect on endothelial cells as a result of a superoxide-dependent mechanism, which induces changes in permeability of the vasculature of the tumor. This agent may stimulate tumor necrosis and promote shunting of blood flow to viable regions of the tumor, increasing their oxygenation and rendering them more susceptible to the antitumor effects of hyperthermia and ionizing radiation. (NCI04) ( NCI )] (UMLS (NCI) C0060441) =Organic Chemical; Pharmacologic Substance
|
- 1714. 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboximide-1,1-dioxide
- [4-hydroxy-2-methyl-N-2-pyridyl-2H-1,2- benzothiazine-3-carboxamide- 1,1-dioxide; nonsteroidal antiinflammatory drug (NSAID) which functions by inhibiting prostaglandin synthesis; effective against colon cancer. ( CSP )] (UMLS (NCI) C0031990) =Organic Chemical; Pharmacologic Substance ;
=antiinflammatory agent;
[AN000] ANTINEOPLASTICS;
thiazine;
antiarthritic agent;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;
=PIROXICAM 10 MG;
PIROXICAM 20 MG;
| - 1764. 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-Tetrahydro-6-methyl-, Hydrochloride,(6aR)-
- [The hydrochloride salt form of apomorphine, a derivative of morphine and non-ergoline dopamine agonist with high selectivity for dopamine D2, D3, D4 and D5 receptors. Apomorphine hydrochloride acts by stimulating dopamine receptors in the nigrostriatal system, hypothalamus, limbic system, pituitary gland, and blood vessels. This enhances motor function, suppresses prolactin release, and causes vasodilation and behavioral effects. Apomorphine hydrochloride is used in the treatment of Parkinson's disease and erectile dysfunction. In addition, apomorphine hydrochloride acts on the chemoreceptor trigger zone and is used as a central emetic in the treatment of drug overdose. ( NCI )] (UMLS (NCI) C0237406) =Organic Chemical; Pharmacologic Substance =apomorphine;
TO BE DELETED INGREDIENT PREPARATIONS =APOMORPHINE HYDROCHLORIDE 6 MG;
|
- 1715. 4-hydroxy-3,7-dimethoxy-17-methylmorphin-7-en-6-one
- [An alkaloid isolated from the root of Sinomenium acutum with immunomodulatory and potential anti-angiogenic and activities. Although the mechanism of action remains to be fully elucidated, sinomenine appears to inhibit endothelial proliferation mediated through basic fibroblast growth factor (bFGF), which may contribute to its anti-angiogenic effect. In Chinese medicine, this agent has a long track-record in treating arthritis, which is accounted by its ability to inhibit proliferation of synovial fibroblasts and lymphocytes. In addition, sinomenine has been shown to suppress expressions of genes involved in inflammation and apoptosis, such as interleukin-6, a pleiotropic inflammatory cytokine and JAK3 (Janus kinase 3), Daxx (death-associated protein 6), plus HSP27 (heat shock 27kDa protein 1), respectively. ( NCI )] (UMLS (NCI) C0074568) =Organic Chemical; Pharmacologic Substance ;
| - 1765. 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic Acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-, Ethyl Ester
- [An imidazo-benzodiazepine derivative, effective in reversing benzodiazepine-induced activities. Flumazenil antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel opening events and inhibiting neuronal hyperpolarization. As a result, flumazenil reverses benzodiazepine-induced effects including sedation, psychomotor deficits, amnesia, and hypoventilation in a dose-dependent manner. ( NCI )] (UMLS (NCI) C0016293) =Organic Chemical; Pharmacologic Substance ;
=Benzodiazepinones;
[AD900] ANTIDOTES/DETERRENTS, OTHER =FLUMAZENIL 0.1 MG/ML |
- 1716. 4-Hydroxyacetanilide
- [analgesic antipyretic derivative of acetanilide; weak antiinflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage. ( CSP )] (UMLS (NCI) C0000970) =Organic Chemical; Pharmacologic Substance ;
| - 1766. 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, Monohydrochloride
- [The hydrochloride salt form of molindone, a dihydroindolone compound with antipsychotic and anti-schizophrenic properties not structurally related to other major tranquilizers. Molindone hydrochloride exerts its effect by blocking dopamine receptors, probably D2 and D3, in the reticular activating and limbic systems, thereby decreasing dopamine excess in the brain. This leads to a reduction of spontaneous locomotion and aggressiveness, suppression of conditioned response, antagonism of stereotyped behaviour and hyperactivity induced by amphetamines. ( NCI )] (UMLS (NCI) C0282249) =Organic Chemical; Pharmacologic Substance ;
=MOLINDONE;
=MOLINDONE HYDROCHLORIDE 100 MG;
MOLINDONE HYDROCHLORIDE 20 MG/ML;
MOLINDONE HYDROCHLORIDE 50 MG;
MOLINDONE HYDROCHLORIDE 10 MG;
MOLINDONE HYDROCHLORIDE 25 MG;
MOLINDONE HYDROCHLORIDE 5 MG;
|
- 1717. 4-Hydroxyandrost-4-ene-3,17-dione
- [A synthetic steroidal substance with antineoplastic activity. Formestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. (NCI04) ( NCI )] (UMLS (NCI) C0048306) =Organic Chemical; Pharmacologic Substance
| - 1767. 4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, Dihydrochloride,(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-
- [The hydrochloride salt form of spectinomycin, an aminocyclitol antibiotic derived from Streptomyces spectabilis with antibacterial property. Spectinomycin hydrochloride binds to the bacterial 30S ribosomal subunit, thereby inhibiting peptide elongation and protein synthesis, consequently leading to bacterial cell death. ( NCI )] (UMLS (NCI) C0887525) Spectinomycin Dihydrochloride;
SPECTINOMYCIN HYDROCHLORIDE;
Spectinomycin Hydrochloride Anhydrous;
SPECTINOMYCIN HYDROCHLORIDE PREPARATION;
Spectogard;
=Organic Chemical; Antibiotic ;
=SPECTINOMYCIN;
=SPECTINOMYCIN HYDROCHLORIDE 2 GM/VIL |
- 1718. 4-hydroxyanisole
- [A synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its effect by oxidation of tyrosinase to cytotoxic products in melanocytes. Mequinol may also act by competitively inhibiting the formation of melanin precursors. ( NCI )] (UMLS (NCI) C0048318) =Organic Chemical; Pharmacologic Substance
| - 1768. 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic Acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, Disodium Salt
- [The sodium salt form of nedocromil, a pyranoquinolone derivative with anti-inflammatory properties. Nedocromil sodium inhibits the activation and release of inflammatory mediators (leukotrienes, histamine and prostaglandins) from a variety of cells involved in hypersensitivity reactions, including mast cells, eosinophils, neutrophils, macrophages, monocytes and platelets. As a result, nedocromil sodium inhibits both immediate and late bronchoconstriction, decreases bronchial hyperresponsiveness and inhibits recruitment of other inflammatory cells into the airway epithelium. ( NCI )] (UMLS (NCI) C0886658) FPL 59002KP;
NEDOCROMIL SODIUM;
NEDOCROMIL SODIUM PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=NEDOCROMIL;
=NEDOCROMIL SODIUM 1.75 MG/ACTUAT;
NEDOCROMIL SODIUM 2 %;
|
- 1719. 4-Hydroxytamoxifen
- [A tamoxifen metabolite with both estrogenic and anti-estrogenic effects. 4-hydroxytamoxifen has a higher affinity for the estrogen receptor than tamoxifen, and functions as an antagonist in breast cancer cells. (NCI04) ( NCI )] (UMLS (NCI) C0048403) =Organic Chemical; Pharmacologic Substance
| - 1769. 4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-
- [A pyrazinoisoquinoline derivative with anthelminthic property. Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm. The result is the formation of granulomas and phagocytosis. ( NCI )] (UMLS (NCI) C0032911) =Organic Chemical; Pharmacologic Substance ;
=Anthelminthics;
2 benzazine =PRAZIQUANTEL 600 MG |
- 1720. 4-imino-1,3-diazabicyclo[3,1,0]-hexan-2-one
- (UMLS (NCI) C0097147) =Organic Chemical; Pharmacologic Substance ;
| - 1770. 4H-Pyrido(1,2-a)pyrimidin-4-one, 9-methyl-3-(1H-tetrazol-5-yl)-, Potassium Salt
- [The potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium exerts its action by blocking the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, histamine and leukotrienes, which are involved in the allergic process. Pemirolast potassium also prevents inflammatory mediator release from eosinophils. ( NCI )] (UMLS (NCI) C0872971) Pemirolast Potassium;
PEMIROLAST POTASSIUM PREPARATION;
PEMIROLAST POTASSIUM UNIDENTIFIED =Organic Chemical; Pharmacologic Substance ;
=Pemirolast;
Unclassified Ingredients |
- 1721. 4-Isoxazolecarboxamide, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-
- [An anticancer drug that works by inhibiting a cancer cell growth factor. Also called SU101. ( NCI )] (UMLS (NCI) C0063041) =Organic Chemical; Pharmacologic Substance ;
=isoxazole;
[MS109] ANTIRHEUMATICS, OTHER =LEFLUNOMIDE 10 MG;
LEFLUNOMIDE 20 MG;
LEFLUNOMIDE 100 MG | - 1771. 4H-Pyrrolo(3,2-d)pyrimidin-4-one,1,5-dihydro-2-amino-7-(3-pyridinylmethyl)
- [A substance that is being studied for the treatment of cancer. ( NCI )] (UMLS (NCI) C0338278) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 1722. 4-Methylphenol
- (UMLS (NCI) C0048212) =Organic Chemical ;
| - 1772. 4i
- [Maxillary right second premolar implant ( HL7V3.0 )] (UMLS (HL7) C1552168) =Medical Device =Artificial dentition;
|
- 1723. 4-Nitroestrone
- [A synthetic derivative of estradiol. 4-nitroestrone 3-methyl ether inhibits estrogen sulfotransferase (EST), a progesterone-induced secretory endometrial enzyme which affects estrogen receptor levels. This agent has been shown to be an effective growth inhibitor of some chemically induced animal mammary tumors. (NCI04) ( NCI )] (UMLS (NCI) C0048573) =Steroid; Pharmacologic Substance ;
| - 1773. 4p
- [Maxillary right second premolar prosthesis ( HL7V3.0 )] (UMLS (HL7) C1552219) =Body Part, Organ, or Organ Component =Artificial dentition;
|
- 1724. 4-Nitropyrene
- [A synthetic, orange needle-shaped solid that is that is practically insoluble in water and soluble in diethyl ether, acetone, ethanol, benzene and toluene. It is not used for any commercial applications and is used only for research purposes. When heated to decomposition, 4-nitropyrene emits toxic fumes of nitrogen oxides. 4-Nitropyrene is found in particulate emissions from combustion products, of which diesel exhaust is the principle source. The primary route of potential human exposure to 4-nitropyrene is inhalation. Low concentrations of 6-nitrochrysene have been found in ambient airborne particulates. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0048629) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 1774. 4pd
- [Maxillary right second premolar distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1552218) =Medical Device =Artificial dentition;
|
- 1725. 4-Nitrosomorpholine
- [A yellow, crystalline nitrosamine that is sensitive to light. N-Nitrosomorpholine is not used or produced commercially in the US. This substance has been found as a contaminant in rubber products, including rubber nipples for baby bottles, and is also found in several vegetables, cheeses, alcoholic beverages and fruits. N-Nitrosomorpholine is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0068232) =Organic Chemical; Hazardous or Poisonous Substance
| - 1775. 4pm
- [Maxillary right second premolar mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1552220) =Medical Device =Artificial dentition;
|
- 1726. 4-o-Tolylazo-o-Toluidine
- [A synthetic organic azo dye used mainly in experimental research, carcinogenic o-Aminoazotoluene induces hepatomas, lung tumors, bladder tumors, and lung hemangioendotheliomas in animals when administered in the diet. (NCI04) ( NCI )] (UMLS (NCI) C0028746) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 1776. 4q Chemokine
- [Members of the Alpha-Chemokines are referred to also as the 4q chemokine family because the genes encoding members of this family map to human chromosome 4q12-21. The first two cysteine residues of members of this family are separated by a single amino acids and these proteins, therefore, are called also CXC-Chemokines. Some members of the subgroup of the human CXC-Chemokines are defined by the conserved ELR sequence motif (glutamic acid-leucine-arginine) immediately preceding the first cysteine residue near the amino-terminal end. Chemokines with an ELR sequence motif have been found to chemoattract and activate primarily neutrophils. Chemokines without the ELR sequence motif appear to chemoattract and activate monocytes, dendritic cells, T-cells, NK-cells, B-lymphocytes, basophils, and eosinophils. ( NCI )] (UMLS (NCI) C0282553) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 1727. 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, Monopotassium Salt,(2R-(2alpha,3Z,5alpha))-
- [A semi-synthetic beta-lactamase inhibitor isolated from streptomyces. Clavunalate potassium contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site. This protects other beta-lactam antibiotics from beta-lactamase catalysis. This drug is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms. ( NCI )] (UMLS (NCI) C0137997) =Organic Chemical; Antibiotic =CLAVULANATE;
=CLAVULANATE POTASSIUM 100 MG/100ML;
CLAVULANATE POTASSIUM 62.5 MG/5ML;
CLAVULANATE POTASSIUM 62.5 MG;
CLAVULANATE POTASSIUM 57 MG/5ML;
CLAVULANATE POTASSIUM 28.5 MG;
CLAVULANATE POTASSIUM 28.5 MG/5ML;
CLAVULANATE POTASSIUM 31.25 MG/5ML;
CLAVULANATE POTASSIUM 125 MG;
CLAVULANATE POTASSIUM 57 MG;
CLAVULANATE POTASSIUM 0.1 GM/VIL;
CLAVULANATE POTASSIUM 42.9 MG/5ML;
CLAVULANATE POTASSIUM 31.25 MG;
| - 1777. 4s
- [Supernumerary maxillary right second premolar ( HL7V3.0 )] (UMLS (HL7) C1552118) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 1728. 4-Pergamid
- (UMLS (NCI) C1328687) Pergamid;
=Organophosphorus Compound; Pharmacologic Substance ;
| - 1778. 5
- [Maxillary right first premolar ( HL7V3.0 )] (UMLS (HL7) C0227038) tooth 5 =Body Part, Organ, or Organ Component =Permanent dentition;
|
- 1729. 4-Phenylbutyric Acid
- (UMLS (NCI) C0170531) =Organic Chemical
| - 1779. 5 Alpha-Reductase Inhibitor
- [Substances that inhibit 5-alpha-Reductase, an enzyme that metabolizes testosterone to dihydrotestosterone, and can reduce prostate size. ( NCI )] (UMLS (NCI) C1318898) 5-alpha Reductase Inhibitors;
=Pharmacologic Substance ;
=enzyme inhibitor;
|
- 1730. 4-Piperidinecarboxylic Acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, Monohydrochloride
- [A phenylpiperidine with antidiarrheal activity and active metabolite of diphenoxylate. Difenoxin is chemically related to the narcotic opioid meperidine. Difenoxin hydrochloride acts primarily on the gastrointestinal wall by binding to opioid receptors on acetylcholine-containing nerves and inhibits the release of acetylcholine from presynaptic nerve terminals. This leads to a reduction in intestinal motility. Difenoxin hydrochloride also mimics the action of endogenous opioid peptides at the CNS opioid receptors, (primarily mu-receptors), thereby inducing CNS effects. ( NCI )] (UMLS (NCI) C0770333) Difenoxin Hydrochloride;
DIFENOXIN HYDROCHLORIDE PREPARATION;
Isonipecotic Acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, Hydrochloride =Organic Chemical; Pharmacologic Substance ;
=Difenoxin;
=DIFENOXIN HYDROCHLORIDE 1 MG;
| - 1780. 5 aminolevulinate synthase
- [An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37. ( MSH )] (UMLS (CSP) C0002565) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 1731. 4-Piperidinecarboxylic Acid, 1-(4-cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenyl-, Monohydrochloride,(-)-(1(cis)3alpha,4beta)-
- [The hydrochloride salt form of levocabastine, a synthetic piperidine derivative with antihistamine properties. Levocabastine is a second generation histamine-1 receptor antagonist. When applied locally into the eye as a topical solution, this agent reduces itching, rhinorrhea and symptoms of allergic rhinitis or conjunctivitis. ( NCI )] (UMLS (NCI) C0771194) Levocabastine Hydrochloride;
LEVOCABASTINE HYDROCHLORIDE PREPARATION;
R 50,547;
=Organic Chemical; Pharmacologic Substance =LEVOCABASTINE;
=LEVOCABASTINE HYDROCHLORIDE 0.05 %;
| - 1781. 5 bromodeoxycytidine
- [5-Bromo-2'-deoxycytidine. Can be incorporated into DNA in the presence of DNA polymerase, replacing dCTP. ( MSH )] (UMLS (CSP) C0006232) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance
|
- 1732. 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, Sodium Salt,(2S-cis)-
- [The sodium salt form of sulbactam, a beta-lactam with weak antibacterial property. Sulbactam sodium contains a beta-lactam ring and irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics. Combining this agent with a beta-lactamase sensitive antibiotic such as penicillins and cephalosporins against penicillinase-producing and beta-lactamase-producing organisms, results in a decreased turnover rate of the sensitive antibiotic and enhances its antibacterial property. ( NCI )] (UMLS (NCI) C0282355) =Organic Chemical; Antibiotic ;
=SULBACTAM;
=SULBACTAM SODIUM 1.5 GM/VIL;
SULBACTAM SODIUM 3 GM/VIL;
SULBACTAM SODIUM 5 GM;
| - 1782. 5 bromodeoxyuridine
- [nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite; causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent; it has been given orphan drug status for use in the treatment of primary brain tumors. ( CSP )] (UMLS (CSP) C0006233) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =deoxyuridine;
halocarbon compound;
nucleoside analog;
|
- 1733. 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-,(2S-(2alpha,5alpha,6beta))-, Monosodium Salt
- [The sodium salt form of benzylpenicillin, a semi-synthetic, broad-spectrum penicillin antibiotic with bactericidal activity. Benzylpenicillin sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. ( NCI )] (UMLS (NCI) C0037540) =Organic Chemical; Antibiotic ;
=Penicillin G Benzathine;
PENICILLIN G PROCAINE;
PENICILLIN;
=PENICILLIN G SODIUM 5000000 UNT | - 1783. 5 bromouracil
- [5-bromo-2,4(1H,3H)-pyrimidinedione; brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA; used mainly as an experimental mutagen. ( CSP )] (UMLS (CSP) C0006242) =Nucleic Acid, Nucleoside, or Nucleotide; Hazardous or Poisonous Substance =uracil analog;
|
- 1734. 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-, Monopotassium Salt
- [The potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic. Penicillin G potassium binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, which is a critical component of the bacterial cell wall. This leads to the interruption of cell wall synthesis, consequently leading to bacterial cell growth inhibition and cell lysis. ( NCI )] (UMLS (NCI) C0700462) =Organic Chemical; Antibiotic =Penicillin G Benzathine;
PENICILLIN G PROCAINE;
PENICILLIN;
=PENICILLIN G POTASSIUM 40000 UNT/ML;
PENICILLIN G POTASSIUM 20000 UNT/ML;
PENICILLIN G POTASSIUM 30000 UNT/ML;
PENICILLIN G POTASSIUM 5000000 UNT;
PENICILLIN G POTASSIUM 20000000 UNT;
PENICILLIN G POTASSIUM 1000000 UNT;
| - 1784. 5 fluorodeoxycytidine
- [ ] (UMLS (CSP) C0597703) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance =deoxycytidine;
halocarbon compound;
nucleoside analog;
|
- 1735. 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(((1-aminocyclohexyl)carbonyl)amino)-3,3-dimethyl-7-oxo-,(2S-(2alpha,5alpha,6beta))-
- [A semi-synthetic beta-lactam aminocyclohexylpenicillin antibiotic. Cyclacillin is bactericidal and binds to specific penicllin-binding proteins, thereby inhibiting transpeptidation during peptidoglycan synthesis. This leads to an interruption of the bacterial cell wall, causing instability of bacterial cell wall and results in cell lysis. Cyclacillin is beta-lactamase susceptible. ( NCI )] (UMLS (NCI) C0010523) =Organic Chemical; Antibiotic ;
=Penicillanic Acid;
[AM052] PENICILLINS, AMINO DERIVATIVES | - 1785. 5 fluorouridine
- [uridine analogs; 18F-labeled compound. ( CSP )] (UMLS (CSP) C0049192) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =deoxyuridine;
fluoropyrimidine;
halocarbon compound;
nucleoside analog |
- 1736. 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-((2,6-dimethoxybenzoyl)amino)-3,3-dimethyl-7-oxo-, Monosodium Salt, Monohydrate,(2S-(2alpha,5alpha,6beta))-
- [The sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity. Methicillin sodium is bactericidal and binds to specific penicillin-binding proteins on the bacterium and inhibits the transpeptidation enzyme, thereby preventing the cross-linking of peptidoglycans. This leads to an interruption of the bacterial cell wall and causes bacterial lysis. Methicillin sodium is active against beta-lactamase producing staphylococci. ( NCI )] (UMLS (NCI) C0887175) Celbenin;
METHICILLIN SODIUM;
METHICILLIN SODIUM PREPARATION;
=Organic Chemical; Antibiotic ;
=2,6 dimethoxyphenylpenicillin;
| - 1786. 5 hours post challenge
- (UMLS (HL7) C1547081) =Temporal Concept =Time delay post challenge;
|
- 1737. 4-Thiazolidine Carboxylic Acid
- [A cyclic sulfur amino acid derivative with potential antineoplastic and antioxidant activity. Thiazolidine carboxylic acid (TCA) acts on cellular membranes of malignant cells through an unknown mechanism to induce reverse transformation, a term denoting changes in morphological and growth characteristics that cause malignant cells to revert back to an untransformed state. TCA produces anti-proliferative effects by restoring contact inhibition, a phenomenon characterized by the paracrine inhibition of mitosis following the formation of a critical cell mass, which is presumably the result of cell-to-cell signal transfer. This drug may also produce antioxidant effects secondary to its release of cysteine and restoration of glutathione concentrations, an important protective property useful against DNA-damaging agents, including chemotherapy and radiation. ( NCI )] (UMLS (NCI) C0076425) =Organic Chemical; Pharmacologic Substance
| - 1787. 5 hydroxytryptamine
- [biochemical messenger and regulator, synthesized from tryptophan; in humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. ( CSP )] (UMLS (CSP) C0036751) =Organic Chemical; Neuroreactive Substance or Biogenic Amine ;
=Neurotransmitter;
tryptamine |
- 1738. 4-Thiazolidinecarboxamide, N-(1,1-dimethylethyl)-3- [2-hydroxy-3-[[2-[[(5-isoquinolinyloxy)acetyl]amino]-3- (methylthio)-1-oxopropyl]amino]-1-oxo-4-phenylbutyl]-,[4R-[3[2S*, 3S*(R*)],4R*]]
- [A synthetic peptide-based antiviral agent. As a peptidomimetic substrate containing an unnatural amino acid, allophenylnorstatine, KNI-272 selectively binds to and inhibits the human immunodeficiency virus (HIV) 1 and 2 proteases, thereby preventing cleavage of the gag-pol viral polyprotein and resulting in the release of immature, noninfectious virions. (NCI04) ( NCI )] (UMLS (NCI) C0174543) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 1788. 5 methoxy N,N dimethyltryptamine
- [major of two hallucinogenic components of Teonanacatl, the sacred mushroom of Mexico, the other component being psilocin. ( CSP )] (UMLS (CSP) C0000588) =Organic Chemical; Biologically Active Substance ;
|
- 1739. 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide
- [An antineoplastic agent that inhibits the Bcr-Abl fusion protein tyrosine kinase, an abnormal enzyme produced by chronic myeloid leukemia cells that contain the Philadelphia chromosome. Imatinib also inhibits the receptor tyrosine kinases for platelet-derived growth factor (PDGF) and stem cell factor (SCF)/c-kit; the SCF/c-kit receptor tyrosine kinase is activated in gastrointestinal stromal tumor (GIST). This agent inhibits proliferation and induces apoptosis in cells that overexpress these oncoproteins. ( NCI )] (UMLS (NCI) C0935989) Imatinib;
IMATINIB PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Unclassified Ingredients =4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide Monomethanesulfonate;
IMATINIB 100 MG | - 1789. 5 methoxytryptamine
- [compounds that contain the biogenic monoamine tryptamine and are substituted with one methoxy group and two methyl groups; members of this group include several potent serotonergic hallucinogens found in several unrelated plants, skins of certain toads, and in mammalian brains; they are possibly involved in the etiology of schizophrenia. ( CSP )] (UMLS (CSP) C0000589) =Organic Chemical; Pharmacologic Substance
|
- 1740. 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide Monomethanesulfonate
- [A drug that is being studied for its ability to inhibit the growth of certain cancers. It interferes with a portion of the protein produced by the bcr/abl oncogene. Also called Gleevec and STI571. ( NCI )] (UMLS (NCI) C0939537) Imatinib Mesylate;
IMATINIB MESYLATE PREPARATION =Organic Chemical; Pharmacologic Substance =4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide;
Unclassified Ingredients =IMATINIB MESYLATE 100 MG;
IMATINIB MESYLATE 400 MG | - 1790. 5 methylcytosine
- [a methylated nucleotide base found in eukaryotic DNA. ( CSP )] (UMLS (CSP) C0049308) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance =cytosine analog;
|
- 1741. 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol Hydrochloride
- [The hydrochloride salt form of isoproterenol, a synthetic catechol compound and potent beta adrenergic agonist with peripheral vasodilator, bronchodilator, and cardiac stimulating properties. Isoproterenol exerts its effect on the beta1-receptors in the myocardium, thereby increasing heart rate and cardiac output. In addition, isoproterenol acts on beta2-receptors in bronchiolar and vascular smooth muscle, thereby causing smooth muscle relaxation. ( NCI )] (UMLS (NCI) C0282210) =Organic Chemical; Pharmacologic Substance =isoprenaline;
=ISOPROTERENOL HYDROCHLORIDE 0.2 MG/ML;
| - 1791. 5 minutes post challenge
- (UMLS (HL7) C1547082) =Temporal Concept =Time delay post challenge;
|
- 1742. 4-[2-[4-(3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
- [A synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post-translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras proteins have been found in a wide range of human cancers. (NCI04) ( NCI )] (UMLS (NCI) C1257385) 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide;
Lonafarnib;
=Organic Chemical; Pharmacologic Substance ;
| - 1792. 5' 3' exonuclease
- [Five Prime-Three Prime Exonucleases specifically catalyze the hydrolysis of terminal phosphodiester bonds of nucleic acids. Human XRN1 and XRN2 are similar to mouse Dhm1 and yeast dhp1, involved in homologous recombination, meiosis, telomere maintenance, RNA synthesis and RNA trafficking. XRN1 localizes to cytoplasmic complexes of mRNA-degrading enzymes and prefers RNA over DNA substrates. XRN2 promotes transcription termination by 5-prime to 3-prime exonuclease activity and autocatalytic cotranscriptional cleavage that may induce dissociation of RNA polymerase II from the DNA template, but function has not yet been fully determined. ( NCI )] (UMLS (CSP) C0094209) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 1743. 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol
- [A phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. Perphenazine blocks postsynaptic dopamine 2(D2) receptors in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby preventing the excess of dopamine in the brain. This leads to reduction in psychotic symptoms, such as hallucinations and delusions. Perphenazine appears to exert its antiemetic activity by blocking the dopamine and histamine-1 receptor in the CTZ thereby relieving nausea and vomiting in the brain. In addition, perphenazine binds to alpha-adrenergic receptors. ( NCI )] (UMLS (NCI) C0031184) =Organic Chemical; Pharmacologic Substance =Phenothiazine;
[CN701] PHENOTHIAZINES/RELATED, ANTIPSYCHOTICS =PERPHENAZINE 16 MG;
PERPHENAZINE 2 MG;
PERPHENAZINE 16 MG/5ML;
PERPHENAZINE 8 MG;
PERPHENAZINE 4 MG | - 1793. 5' exonuclease
- [A phosphoric diester hydrolase that removes 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated OLIGONUCLEOTIDES. It has low activity towards POLYNUCLEOTIDES and the presence of 3'-phosphate terminus on the substrate may inhibit hydrolysis. ( MSH )] (UMLS (CSP) C0070828) =Amino Acid, Peptide, or Protein; Enzyme =PDE;
|
- 1744. 4-[4'-(Methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone
- [A substance used for pain relief that is also being studied for its ability to prevent cancer and to block the growth of new blood vessels to solid tumors. It belongs to the family of drugs called nonsteroidal anti-inflammatory drugs. ( NCI )] (UMLS (NCI) C0762662) Rofecoxib;
ROFECOXIB PREPARATION;
=Organic Chemical; Pharmacologic Substance =LACTONE;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC =ROFECOXIB 50 MG;
ROFECOXIB 12.5 MG/5ML;
ROFECOXIB 25 MG/5ML;
ROFECOXIB 25 MG;
ROFECOXIB 12.5 MG;
| - 1794. 5' nucleotidase
- [A class of enzymes present in various organs and in many cells that catalyze the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. Serum 5'-N'Tase is measured as an indicator of liver damage resulting primarily from interference with the secretion of bile. Serum 5'-N'Tase is not as sensitive as some other enzymes (for example, ALP, AST, and ALT) to liver damage, but it is a more liver-specific enzyme. The level of this enzyme parallels alkaline phosphatase (ALP). It is used mostly to differentiate elevations in the above enzymes due to liver damage from damage to skeletal muscle. ( NCI )] (UMLS (CSP) C0000530) =Amino Acid, Peptide, or Protein; Enzyme; Immunologic Factor
|
- 1745. 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone
- [USP lists as an antipsychotic and as an "antidyskinetic" used in Tourette syndrome. ( CSP )] (UMLS (NCI) C0018546) =Organic Chemical; Pharmacologic Substance =butyrophenone;
piperidine;
[CN700] ANTIPSYCHOTICS;
Dopamine Antagonist;
[CN709] ANTIPSYCHOTICS, OTHER;
=HALOPERIDOL DECANOATE;
HALOPERIDOL LACTATE;
HALOPERIDOL DECANOATE;
HALOPERIDOL LACTATE;
HALOPERIDOL 0.5 MG;
HALOPERIDOL 1 MG;
HALOPERIDOL 10 MG;
HALOPERIDOL 2 MG;
HALOPERIDOL 2 MG/ML;
HALOPERIDOL 20 MG;
HALOPERIDOL 5 MG;
HALOPERIDOL 5 MG/ML;
| - 1795. 5' Untranslated Region
- [Sequences on the 5' end of messenger RNAs that are not translated into protein. 5'UTR extends from the transcription start site to just before the ATG translation initiation codon. This region contains the ribosome binding site and other transcription and translation regulating sequences. ( NCI )] (UMLS (NCI) C0600493) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
|
- 1746. 4-[bis(2-chloroethyl)amino]-L-phenylalanine
- [4-bis-(2-chloroethyl)amino-L-phenylalanine; a bifunctional alkylating agent used as a DNA strand crosslinker and antineoplastic. ( CSP )] (UMLS (NCI) C0025241) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Bis(2-chloroethyl)methylamine;
Nitrogen Mustard Compound;
phenylalanine;
Antineoplastic Alkylating Agent;
=3-(p-(bis(2-chloroethyl)amino)phenyl)-L-Alanine, Hydrochloride;
MELPHALAN 2 MG;
| - 1796. 5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-cytidine
- [An anticancer drug that belongs to the family of drugs called antimetabolites. ( NCI )] (UMLS (NCI) C0671970) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
deoxycytidine =CAPECITABINE 150 MG;
CAPECITABINE 500 MG |
- 1747. 4-[[Hydroxy(octadecyloxy)phosphinyl]oxy]-1,1-dimethylpiperidinium, Inner Salt
- [An anticancer drug that belongs to the family of drugs called alkyl phospholipids. ( NCI )] (UMLS (NCI) C0754570) Octadecyl-(N,N-dimethylpiperidino-4-yl)phosphate;
Octadecylphosphopiperidine;
PERIFOSINE;
=Organophosphorus Compound; Pharmacologic Substance | - 1797. 5'-Deoxy-5-fluorouridine
- [A fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by dihydropyrimidine dehydrogenase in the gut wall, is converted into 5-FU in the presence of pyrimidine nucleoside phosphorylase. 5-FU interferes with DNA synthesis and subsequent cell division by reducing normal thymidine production and interferes with RNA transcription by competing with uridine triphosphate for incorporation into the RNA strand. ( NCI )] (UMLS (NCI) C0048808) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
|
- 1748. 40-49% BDY BRN/10-19% 3D
- [ ] (UMLS (ICD9CM) C0161343) =Injury or Poisoning
| - 1798. 5'-Inosinic Acid, Homopolymer Complex with 5'-Cytidylic Acid Homopolymer
- [interferon inducer consisting of a synthetic, mismatched double-stranded RNA; the polymer is made of one strand each of polyinosinic acid and polycytidylic acid. ( CSP )] (UMLS (NCI) C0032414) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =interferon inducer;
polynucleotide |
- 1749. 40-49% BDY BRN/20-29% 3D
- [ ] (UMLS (ICD9CM) C0161344) =Injury or Poisoning
| - 1799. 5'-tct ccc agc gtg cgc cat
- [A drug that may kill cancer cells by blocking the production of a protein that makes cancer cells live longer. ( NCI )] (UMLS (NCI) C0914297) Oblimersen;
olbimersen =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
|
- 1750. 40-49% BDY BRN/3 DEG NOS
- [ ] (UMLS (ICD9CM) C0161342) =Injury or Poisoning
| - 1800. 5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine Hydroxide, Inner Salt
- [physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms; possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. ( CSP )] (UMLS (NCI) C0036002) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance =adenosine;
L-Methionine;
high energy compound;
|
home
