- 1. (+)-(4S)-4,11-diethyl-4-hydroxy-9-[(4-piperidino-piperidino)carbonyloxy]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinol-3,14,(4H,12H)-dione
- [DNA topoisomerase I inhibitor. ( CSP )] (UMLS (NCI) C0123931) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
(+)-Camptothecin;
enzyme inhibitor;
=Irinotecan Hydrochloride | - 51. *Substance Concentration Ratio
- (UMLS (HL7) C1264681) =Quantitative Concept =Kind of quantity;
|
- 2. (+)-(S)-4,4'-(1-Methyl-1,2-ethanediyl)di(2,6-piperazinedione)
- [A drug used to protect the heart from the toxic effects of anthracycline drugs such as doxorubicin. It belongs to the family of drugs called chemoprotective agents. ( NCI )] (UMLS (NCI) C0086444) =Organic Chemical; Pharmacologic Substance ;
=Razoxane;
[CV900] CARDIOVASCULAR AGENTS, OTHER =Dexrazoxane Hydrochloride;
| - 52. *Substance Content
- (UMLS (HL7) C1547042) =Quantitative Concept =Kind of quantity;
|
- 3. (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
- [An imidazole derivate and active d-isomer of medetomidine with analgesic, anxiolytic and sedative properties. Dexmedetomidine selectively binds to presynaptic alpha-2 adrenoceptors located in the brain, thereby inhibiting the release of norepinephrine from synaptic vesicles. This leads to an inhibition of postsynaptic activation of adrenoceptors, which inhibit sympathetic activity, thereby leading to sedation and anxiolysis. The analgesic effect of this agent is mediated by binding to alpha2-adrenoceptors in the spinal cord. ( NCI )] (UMLS (NCI) C0113293) =Organic Chemical; Pharmacologic Substance =imidazole;
[CN309] SEDATIVES/HYPNOTICS, OTHER =DEXMEDETOMIDINE HCL | - 53. *Substance Content Rate
- (UMLS (HL7) C1264670) =Quantitative Concept =Kind of quantity;
|
- 4. (+)-Simalikalactone D
- [A quassinoid phytochemical isolated from Simaba multiflora, Quassia africana and other plant species with potential antineoplastic activity. This agent also has antimalarial and antiviral properties. (NCI04) ( NCI )] (UMLS (NCI) C0074548) =Organic Chemical
| - 54. *Substance Fraction
- (UMLS (HL7) C1264665) =Quantitative Concept =Kind of quantity;
|
- 5. (+/-)-Sulforaphane
- [A naturally-occurring phytochemical belonging to the class of isothiocyanates. As the aglycone metabolite of glucosinolate glucoraphanin (sulforaphane glucosinolate), sulforaphane acts as an antioxidant and potent stimulator of endogenous detoxifying enzymes. This agent displays anticarcinogenic properties due to its ability to induce phase II detoxification enzymes, such as glutathione S-transferase and quinone reductase, thereby providing protection against certain carcinogens and toxic, reactive oxygen species. Broccoli sprouts contain large amounts of sulforaphane, which is also found in other cruciferous vegetables including cabbage and kale. (NCI04) ( NCI )] (UMLS (NCI) C0163159) =Organic Chemical; Pharmacologic Substance ;
| - 55. *Substance Rate
- (UMLS (HL7) C1264671) =Quantitative Concept =Kind of quantity;
|
- 6. (-) Strand ssRNA Virus
- [A single stranded RNA virus where the RNA strand is the complement of a mRNA. ( NCI )] (UMLS (NCI) C1093214) Negative Sense ssRNA Virus;
Negative Strand ssRNA Virus;
ssRNA Virus, (-) Strand =Virus ;
| - 56. *Substance Ratio
- (UMLS (HL7) C1264682) =Quantitative Concept =Kind of quantity;
|
- 7. (-)-Salbutamol Hydrochloride
- [The hydrochloride salt form of levalbuterol, a relatively selective sympathomimetic beta2 receptor agonist with bronchodilator activity. Levalbuterol hydrochloride binds to beta2-adrenergic receptors in bronchial smooth muscle and activates intracellular adenyl cyclase, thereby increasing the production of cyclic-3', 5'-adenosine monophosphate (cAMP). Increased cAMP levels lead to the activation of protein kinase A, which inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, resulting in relaxation of bronchial smooth muscles. The increased cyclic AMP concentrations also inhibit the release of inflammatory mediators from mast cells. ( NCI )] (UMLS (NCI) C0772502) 1,3-Benzenedimethanol, alpha1-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, Hydrochloride,(alpha1R)-;
LEVALBUTEROL HYDROCHLORIDE;
=Organic Chemical; Pharmacologic Substance | - 57. *Susceptibility
- (UMLS (HL7) C1547045) =Quantitative Concept =Kind of quantity;
|
- 8. (15S)-15-Methylprostaglandin F(sub 2alpha) Tromethamine
- [A synthetic 15-methyl analogue of the naturally occurring prostaglandin F2alpha. Carboprost tromethamine induces myometrium smooth muscle contraction by binding to the prostaglandin F2alpha receptors. This drug can be used to induce contractions to end pregnancy or to induce labour and to control severe postpartum bleeding. Due to its contractile effects on gastrointestinal smooth muscle, carboprost tromethamine can cause vomiting and diarrhea. ( NCI )] (UMLS (NCI) C0054721) =Organic Chemical; Pharmacologic Substance ;
| - 58. 1
- [The first step in testing a new treatment in humans. These studies test the best way to give a new treatment (for example, by mouth, intravenous infusion, or injection) and the best dose. The dose is usually increased a little at a time in order to find the highest dose that does not cause harmful side effects. Because little is known about the possible risks and benefits of the treatments being tested, phase I trials usually include only a small number of patients who have not been helped by other treatments. ( NCI )] (UMLS (NCI) C0920321) clinical trial phase I;
Clinical Trials, Phase I;
Early-Stage Clinical Trials;
Phase 1 Study;
Phase I Clinical Trials;
Phase I Protocol;
Phase I Study;
phase I trial;
Trial Phase 1 =Research Activity =clinical trial;
|
- 9. (1S,3S)-3-Acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-6,11-dioxo-1-naphthacenyl-3-amino-2,3,6-trideoxy-alpha-L-hexopyranoside
- [An anticancer drug that belongs to the family of drugs called antitumor antibiotics. Also called 4-demethoxydaunorubicin. ( NCI )] (UMLS (NCI) C0020789) =Organic Chemical; Pharmacologic Substance ;
=antineoplastic antibiotics;
(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione =Idarubicin HCl;
| - 59. 10s
- [Supernumerary maxillary left lateral incisor ( HL7V3.0 )] (UMLS (HL7) C1552124) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 10. (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione
- [An enteric-coated formulation of ixabepilone, a semisynthetic analogue of epothilone B and a non-taxane tubulin inhibitor, with antineoplastic activity. Ixabepilone binds to and stabilizes tubulin molecules, thereby interfering with the dynamics of microtubule assembly/disassembly. This results in cell cycle arrest at G2-M phase and leads to apoptosis of fast growing tumor cells. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. Compared to intravenously administered ixabepilone, the oral formulation is a less cumbersome way of administering this agent. ( NCI )] (UMLS (NCI) C1135132) Azaepothilone B;
Epothilone;
IXABEPILONE;
Oral Ixabepilone =Organic Chemical; Pharmacologic Substance ;
| - 60. 11s
- [Supernumerary maxillary left canine ( HL7V3.0 )] (UMLS (HL7) C1552125) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 11. (2S)-2-Methylbutanoic Acid, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester
- [HMG coA reductase inhibitor which inhibits cholesterol biosynthesis and thus lowers blood cholesterol levels; also blocks isoprenylation of protein CAAX motifs. ( CSP )] (UMLS (NCI) C0024027) =Organic Chemical; Pharmacologic Substance ;
=antihypercholesterolemic agent;
[CV350] ANTILIPEMIC AGENTS;
naphthalene;
=[1S-[1alpha,3alpha,7beta,8beta(2S*,4S*),8abeta]]-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl 2,2-dimethylbutanoate;
LOVASTATIN 10 MG;
LOVASTATIN 20 MG;
LOVASTATIN 40 MG;
| - 61. 12s
- [Supernumerary maxillary left first premolar ( HL7V3.0 )] (UMLS (HL7) C1552126) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 12. (2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoxy)propyl)carboyl)-2-hydroxy-5-methylhexanohydroxamic Acid
- [An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Marimastat is a matrix metalloproteinase inhibitor. ( NCI )] (UMLS (NCI) C0338344) =Organic Chemical; Pharmacologic Substance
| - 62. 13s
- [Supernumerary maxillary left second premolar ( HL7V3.0 )] (UMLS (HL7) C1552127) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 13. (2S,3S)-3,4-Dimethyl-2-phenylmorpholine L-(+)-tartrate(1:1)
- [A phenylalkylamine sympathomimetic amine with appetite depressant property. Phendimetrazine tartrate is a prodrug that is hydrolyzed to the active metabolite phenmetrazine, which competes with norepinephrine and dopamine for their presynaptic transporters, thereby blocks the reuptake of these monoamines at the neuronal junctions. As a result, this prolongs activities of dopamine and norepinephrine and leads to central nervous system (CNS) stimulation and metabolic effects, including appetite-suppression, decreased gastric acid secretion and increased blood pressure. ( NCI )] (UMLS (NCI) C0148932) =Organic Chemical; Pharmacologic Substance ;
=PHENDIMETRAZINE;
=PHENDIMETRAZINE TARTRATE 35 MG;
PHENDIMETRAZINE TARTRATE 105 MG;
PHENDIMETRAZINE TARTRATE 17.5 MG | - 63. 14-3-3 Sigma
- [Stratifin was first identified as an epithelial cell antigen (HME-1) exclusively expressed in epithelia. The protein is a putative cytoplasmic, p53-regulated homodimeric inhibitor of G2/M progression that is over expressed in squamous cell carcinoma of the head and neck. The gene is a member of a large 14-3-3 gene family. ( NCI )] (UMLS (NCI) C0972212) Epithelial Cell Marker Protein 1;
SFN;
Stratifin =Amino Acid, Peptide, or Protein; Enzyme; Indicator, Reagent, or Diagnostic Aid |
- 14. (2S,3S)-3-acetyl-1,2,3,4,6,11-hexahydro-3,5,10,12-tetrahydroxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
- [An anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0007308) =Organic Chemical; Antibiotic ;
| - 64. 14s
- [Supernumerary maxillary left first molar ( HL7V3.0 )] (UMLS (HL7) C1552128) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 15. (2S,5R,6R)-6-((R)-2-Amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid
- [semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic. ( CSP )] (UMLS (NCI) C0002680) =Organic Chemical; Antibiotic ;
| - 65. 153Sm-EDTMP
- (UMLS (NCI) C0772051) Samarium Sm 153 Lexidronam;
Samarium Sm-153 EDTMP;
Samarium-153 EDTMP;
Samarium-153 Ethylenediaminetetramethylenephosphonate;
Samarium-153 Ethylenediaminetetramethylenephosphonic Acid;
Sm-153 EDTMP =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid |
- 16. (2S-cis)-Benzoic Acid[1-[4-[3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3-naphthacenyl]ethylidene]hydrazide
- [A benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39590&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39590&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1458" NCI Thesaurus) ( PDQ )] (UMLS (NCI) C0206788) =Organic Chemical; Antibiotic ;
| - 66. 15s
- [Supernumerary maxillary left second molar ( HL7V3.0 )] (UMLS (HL7) C1552129) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 17. (3S)-N-Hydroxy-2,2-dimethyl-4-{{4-(4-piridinyloxy)phenyl}sulfonyl}-3-thiomorpholinecarboxamide
- [An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Prinomastat is a matrix metalloproteinase inhibitor. Also called AG3340. ( NCI )] (UMLS (NCI) C0919273) AG3340;
Pinomastat;
Prinomastat;
Prinomastat/AG 3340 =Organic Chemical; Pharmacologic Substance ;
| - 67. 16s
- [Supernumerary maxillary left third molar ( HL7V3.0 )] (UMLS (HL7) C1552130) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 18. (3S,3'S)-3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione
- (UMLS (NCI) C0052565) =Organic Chemical; Biologically Active Substance
| - 68. 17s
- [Supernumerary mandibular left third molar ( HL7V3.0 )] (UMLS (HL7) C1552131) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 19. (4S,4aR,5S,5aR,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide Mono(5-sulfosalicylate)(Salt)
- [The sulfosalicylate salt form of meclocycline, a tetracycline antibiotic with broad-spectrum antibacterial and antiprotozoal activity. Meclocycline sulfosalicylate is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative bacteria. ( NCI )] (UMLS (NCI) C0700494) =Organic Chemical; Antibiotic ;
| - 69. 18s
- [Supernumerary mandibular left second molar ( HL7V3.0 )] (UMLS (HL7) C1552132) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 20. (4S,4aR,5S,5aR,6S,12aS)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide, Monohydrochloride
- [The hydrochloride salt form of oxytetracycline, a tetracycline derivative produced by Streptomyces rimosus exhibiting antimicrobial activity. Oxytetracycline hydrochloride interferes with binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby preventing peptide elongation and inhibiting protein synthesis. It is often used to treat skin conditions. ( NCI )] (UMLS (NCI) C0017449) =Organic Chemical; Antibiotic ;
=OXYTETRACYCLINE;
=OXYTETRACYCLINE 50 MG/ML;
OXYTETRACYCLINE HYDROCHLORIDE 500 MG;
OXYTETRACYCLINE HYDROCHLORIDE 100 MG;
OXYTETRACYCLINE HYDROCHLORIDE 125 MG;
OXYTETRACYCLINE HYDROCHLORIDE 250 MG;
OXYTETRACYCLINE HYDROCHLORIDE 30 MG/GM;
OXYTETRACYCLINE HYDROCHLORIDE 0.5 %;
| - 70. 18S Ribosomal RNA
- [The second largest of the three RNA components of the mammalian ribosome. ( NCI )] (UMLS (NCI) C0035703) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance
|
- 21. (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride
- [The hydrochloride salt form of tetracycline, a broad-spectrum naphthacene antibiotic, produced semisynthetically from chlortetracycline, an antibiotic isolated from the Streptomyces aureofaciens. In bacteria, tetracycline hydrochloride blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis and bacterial cell growth. ( NCI )] (UMLS (NCI) C0546879) =Organic Chemical; Antibiotic =4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide;
[DE752] ANTIACNE AGENTS, TOPICAL;
[OP201] ANTIBACTERIALS, TOPICAL OPHTHALMIC;
=TETRACYCLINE HYDROCHLORIDE 56 X 500 MG;
TETRACYCLINE HYDROCHLORIDE 125 MG/5ML;
TETRACYCLINE HYDROCHLORIDE 250 MG;
TETRACYCLINE HYDROCHLORIDE 500 MG;
TETRACYCLINE HYDROCHLORIDE 2.2 MG/ML;
TETRACYCLINE HYDROCHLORIDE 1 %;
TETRACYCLINE HYDROCHLORIDE 250 MG/ML;
TETRACYCLINE HYDROCHLORIDE 100 MG;
TETRACYCLINE HYDROCHLORIDE 3 %;
TETRACYCLINE HYDROCHLORIDE 100 MG/ML;
| - 71. 19s
- [Supernumerary mandibular left first molar ( HL7V3.0 )] (UMLS (HL7) C1552133) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 22. (4S-(4R*,7S,8R*,9R*,13Z,16R*(E)))-4,8-Dihydroxy-5,5,7,9,13-pentamethyl-16-(1-methyl-2-(2-methyl-4-thiazolyl)ethenyl)oxacyclohexadec-13-ene-2,6-dione
- [A natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Also known as desoxyepothilone B, epothilone D binds to tubulin and inhibits the disassembly of microtubules, resulting in the inhibition of mitosis, cellular proliferation, and cell motility. (NCI04) ( NCI )] (UMLS (NCI) C0962559) 12,13-Deoxyepothilone B;
Desoxyepothilone B;
Epothilone D;
=Organic Chemical; Pharmacologic Substance ;
| - 72. 1s
- [Supernumerary maxillary right third molar ( HL7V3.0 )] (UMLS (HL7) C1552115) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 23. (8S-cis)-10-((3-Amino-2,3,6-trideoxy-beta-L-arabino-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
- [A 4'-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. ( NCI )] (UMLS (NCI) C0014582) =Organic Chemical; Pharmacologic Substance =antineoplastic antibiotics;
(8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroacetyl)-1-methoxy-5,12-naphthacenedione =(8S-cis)-10-((3-Amino-2,3,6-trideoxy-beta-L-arabino-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Hydrochloride | - 73. 1ST DEG BURN ABDOMN WALL
- [ ] (UMLS (ICD9CM) C0840797) Erythema due to burn [first degree] of abdominal wall =Injury or Poisoning
|
- 24. (8S-cis)-10-((3-Amino-2,3,6-trideoxy-beta-L-arabino-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Hydrochloride
- [The hydrochloride salt of the 4'-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. ( NCI )] (UMLS (NCI) C0700582) =Organic Chemical; Pharmacologic Substance =(8S-cis)-10-((3-Amino-2,3,6-trideoxy-beta-L-arabino-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione;
=EPIRUBICIN HCL 2 MG/ML | - 74. 1ST DEG BURN ANKLE
- [ ] (UMLS (ICD9CM) C0161274) =Injury or Poisoning
|
- 25. (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroacetyl)-1-methoxy-5,12-naphthacenedione
- [antineoplastic antibiotic obtained from Streptomyces peucetius; a hydroxy derivative of daunorubicin. ( CSP )] (UMLS (NCI) C0013089) =Organic Chemical; Antibiotic ;
=Anthracycline Antibiotic;
antineoplastic antibiotics;
(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione;
=(8S-cis)-10-((3-Amino-2,3,6-trideoxy-beta-L-arabino-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione;
N-trifluoroacetyladriamycin 14-valerate;
14-Hydroxydaunorubicin Hydrochloride;
(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-tri-hydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride;
14-Hydroxydaunorubicin Hydrochloride;
(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-tri-hydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride;
| - 75. 1ST DEG BURN ARM NOS
- [ ] (UMLS (ICD9CM) C0161157) =Injury or Poisoning
|
- 26. (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-tri-hydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride
- [A liposome-encapsulated form of the hydrochloride salt of the anthracycline antineoplastic antibiotic doxorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids. Liposomal delivery of doxorubicin HCL improves drug penetration into tumors and decreases drug clearance, thereby increasing the duration of therapeutic drug effects; a liposomal formulation of doxorubicin also modulates toxicity, specifically the cardiac effects commonly seen with anthracycline antitumor drugs. ( NCI )] (UMLS (NCI) C1445757) Doxorubicin HCl Liposome;
Doxorubicin Hydrochloride Liposomal;
Doxorubicin Hydrochloride Liposome;
DOXORUBICIN HYDROCHLORIDE LIPOSOME PREPARATION;
Liposomal Doxorubicin Hydrochloride;
=Organic Chemical; Antibiotic =(8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroacetyl)-1-methoxy-5,12-naphthacenedione;
=DOXORUBICIN HYDROCHLORIDE LIPOSOME 2 MG/ML;
| - 76. 1ST DEG BURN ARM-MULT
- [ ] (UMLS (ICD9CM) C0161164) =Injury or Poisoning
|
- 27. (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
- [anthracycline antibiotic produced by Streptomyces coeruleorubidus or Streptomyces peucetius and used as an antineoplastic. ( CSP )] (UMLS (NCI) C0011015) =Organic Chemical; Pharmacologic Substance =Anthracycline Antibiotic;
antineoplastic antibiotics;
Anthracyclines;
=(8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroacetyl)-1-methoxy-5,12-naphthacenedione;
(1S,3S)-3-Acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-6,11-dioxo-1-naphthacenyl-3-amino-2,3,6-trideoxy-alpha-L-hexopyranoside;
5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-, hydrochloride;
DAUNORUBICIN CITRATE LIPOSOME;
5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-, hydrochloride;
DAUNORUBICIN CITRATE LIPOSOME | - 77. 1ST DEG BURN AXILLA
- [ ] (UMLS (ICD9CM) C0161161) =Injury or Poisoning
|
- 28. (9S)-6'-Methoxycinchonan-9-ol Sulfate (2:1) (salt)
- [The sulfate salt form of quinidine, an alkaloid with antimalarial and antiarrhythmic (Class la) properties. Quinidine sulfate exerts its anti-malarial activity by acting primarily as an intra-erythrocytic schizonticide through association with the hemepolymer (hemozoin) in the acidic food vacuole of the parasite thereby preventing further polymerization by heme polymerase enzyme. This results in accumulation of toxic heme and death of the parasite. Quinidine sulfate exerts its antiarrhythmic effects by depressing the flow of sodium ions into cells during phase 0 of the cardiac action potential, thereby slowing the impulse conduction through the atrioventricular (AV) node, reducing the rate of phase 0 depolarization and prolonging the refractory period. Quinidine sulfate also reduces the slope of phase 4 depolarization in Purkinje-fibres resulting in slowed conduction and reduced automaticity in the heart. ( NCI )] (UMLS (NCI) C0034415) =Organic Chemical; Pharmacologic Substance ;
=QUINIDINE;
9S-6'-Methoxy-cinchonan-9-ol, Mono-D-gluconate(salt);
quinidine polygalacturonate;
=QUINIDINE SULFATE 200 MG;
QUINIDINE SULFATE 100 MG;
QUINIDINE SULFATE 300 MG | - 78. 1ST DEG BURN BACK
- [ ] (UMLS (ICD9CM) C0840798) Erythema due to burn [first degree] of back [any part] =Injury or Poisoning
|
- 29. (S)-(-)-Perillyl alcohol
- [A drug used in cancer prevention that belongs to the family of plant drugs called monoterpenes. ( NCI )] (UMLS (NCI) C0207661) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance
| - 79. 1ST DEG BURN BREAST
- [ ] (UMLS (ICD9CM) C0161109) =Injury or Poisoning
|
- 30. (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
- [potent and specific inhibitor of peptidyl dipeptidase A; it acts to suppress the renin-angiotensin system and inhibits blood pressure responses to exogenous angiotensin. ( CSP )] (UMLS (NCI) C0006938) =Amino Acid, Peptide, or Protein; Pharmacologic Substance =Amino Acids, Cyclic;
[CV800] ACE INHIBITORS;
PROLINE;
=CAPTOPRIL 100 MG;
CAPTOPRIL 12.5 MG;
CAPTOPRIL 25 MG;
CAPTOPRIL 50 MG;
| - 80. 1ST DEG BURN CHEST WALL
- [ ] (UMLS (ICD9CM) C0161110) =Injury or Poisoning
|
- 31. (S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
- [A propanolamine derivative and a non-selective beta-adrenergic antagonist with antihypertensive property. Timolol competitively binds to beta-1-adrenergic receptors in the heart and vascular smooth muscle and beta-2-receptors in the bronchial and vascular smooth muscle, resulting in a decrease in beta-adrenergic stimulation. Beta-1-receptor blockade results in a decrease in resting and exercise heart rate and cardiac output, a decrease in both systolic and diastolic blood pressure, and, possibly, a reduction in reflex orthostatic hypotension. Beta-2-blockade results in an increase in peripheral vascular resistance. The ultimate results include vasodilation, and negative chronotropic and inotropic cardiac effects. In addition, timolol reduces intra-ocular pressure possibly by decreasing aqueous humor production by reduction of blood flow to the ciliary processes and cAMP synthesis. ( NCI )] (UMLS (NCI) C0040233) =Organic Chemical; Pharmacologic Substance =Propanolamines;
[CV100] BETA-BLOCKERS/RELATED;
[OP101] BETA-BLOCKERS, TOPICAL OPHTHALMIC;
[OP109] ANTIGLAUCOMA, OTHER =TIMOLOL MALEATE;
TIMOLOL HEMIHYDRATE;
TIMOLOL MALEATE;
TIMOLOL HEMIHYDRATE;
| - 81. 1ST DEG BURN CHIN
- [ ] (UMLS (ICD9CM) C0433307) =Injury or Poisoning
|
- 32. (s)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dione
- [antineoplastic drug which acts as a DNA topoisomerase inhibitor. ( CSP )] (UMLS (NCI) C0146224) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
(+)-Camptothecin =(S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4'
6,7] indolizino[1,2-b] quinoline-3,14-(4H,12H)-dione monohydrochloride | - 82. 1ST DEG BURN EAR
- [ ] (UMLS (ICD9CM) C0161046) =Injury or Poisoning
|
- 33. (S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4'
6,7] indolizino[1,2-b] quinoline-3,14-(4H,12H)-dione monohydrochloride - [An oral formulation of hydrochloride salt of topotecan, a semisynthetic derivative of camptothecin, a quinoline alkaloid extracted from the Asian tree Camptotheca acuminate, with potential antineoplastic activity. Topotecan selectively inhibits topoisomerase I activity by stabilizing the topoisomerase I-DNA covalent complexes during S phase of cell cycle, thereby inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when encountered by the DNA replication machinery. Compared to intravenously administered topotecan, the oral formulation is a more convenient way of administering this agent. ( NCI )] (UMLS (NCI) C0886549) Hycamptamine;
Oral Topotecan Hydrochloride;
Topotecan HCl;
Topotecan hydrochloride;
topotecan hydrochloride (oral);
TOPOTECAN HYDROCHLORIDE PREPARATION =Organic Chemical; Pharmacologic Substance ;
=(s)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dione;
=TOPOTECAN HYDROCHLORIDE 4 MG | - 83. 1ST DEG BURN ELBOW
- [ ] (UMLS (ICD9CM) C0161159) =Injury or Poisoning
|
- 34. (S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole
- [oral imidazole used as an anthelminthic, effective against roundworms, hookworms and strongyloids; also an immunopotentiator; has been used to stimulate immune response in cancer. ( CSP )] (UMLS (NCI) C0023556) =Organic Chemical; Pharmacologic Substance =Anthelminthics;
imidazole;
thiazole;
[AN400] ANTINEOPLASTIC ADJUVANTS =LEVAMISOLE 50 MG | - 84. 1ST DEG BURN EYE
- [ ] (UMLS (ICD9CM) C0161047) =Injury or Poisoning
|
- 35. (S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole Monohydrochloride
- [The chloride salt form of the anthelmintic drug levamisole. Co-administered with fluorouracil in the treatment of Dukes' stage C colon cancer, levamisole restores immune function through stimulating antibody formation, enhancing T-cell activity, and potentiating macrophage function. (NCI04) ( NCI )] (UMLS (NCI) C0733383) Cloridrato de Levamizol;
LEVAMISOLE HYDROCHLORIDE;
l-Tetramisole Hydrochloride;
=Organic Chemical; Pharmacologic Substance | - 85. 1ST DEG BURN FACE NEC
- [ ] (UMLS (ICD9CM) C0161052) =Injury or Poisoning
|
- 36. (S)-alpha-Ethyl-2-oxo-1-pyrrolidineacetamide
- [A pyrrolidine with antiepileptic activity. The exact mechanism through which levetiracetam exerts its effects is unknown but does not involve inhibitory and excitatory neurotransmitter activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity. ( NCI )] (UMLS (NCI) C0377265) =Organic Chemical; Pharmacologic Substance ;
=[CN400] ANTICONVULSANTS;
etiracetam =LEVETIRACETAM 500 MG;
LEVETIRACETAM 250 MG;
LEVETIRACETAM 750 MG;
| - 86. 1ST DEG BURN FINGER
- [ ] (UMLS (ICD9CM) C0161213) =Injury or Poisoning
|
- 37. (S)-alpha-Methylbenzeneethanamine Sulfate
- [The salt of the dextro-isomer of amphetamine and sympathomimetic amine with CNS stimulating properties. Dextroamphetamine sulphate acts by facilitating the release of catecholamines, particularly noradrenaline and dopamine, from nerve terminals in the brain and inhibits their uptake. This leads to an increase in motor activity, causes euphoria, mental alertness and excitement and suppresses appetite. This drug causes dependence and may cause an increase in heart rate and blood pressure. It is used in the treatment of narcolepsy and attention deficit hyperactivity disorder. ( NCI )] (UMLS (NCI) C0011810) =Organic Chemical; Pharmacologic Substance ;
=Dextroamphetamine;
=DEXTROAMPHETAMINE SULFATE 1.25 MG;
DEXTROAMPHETAMINE SULFATE 15 MG;
DEXTROAMPHETAMINE SULFATE 5 MG;
DEXTROAMPHETAMINE SULFATE 5 MG/5ML;
DEXTROAMPHETAMINE SULFATE 7.5 MG;
DEXTROAMPHETAMINE SULFATE 10 MG;
DEXTROAMPHETAMINE SULFATE 2.5 MG;
DEXTROAMPHETAMINE SULFATE 3.75 MG;
| - 87. 1ST DEG BURN FOOT
- [ ] (UMLS (ICD9CM) C0161273) =Injury or Poisoning
|
- 38. (S)-dihydroorotate:oxygen oxidoreductase
- [A flavoprotein (FAD, FMN). Catalyzes the reaction of S-dihydroorotate and oxygen into orotate and hydrogen peroxide. Ferricyanide can act as acceptor. [EC 1.3.3.1 created 1961] (from IUBMB) ( NCI )] (UMLS (NCI) C0058099) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 88. 1ST DEG BURN FOREARM
- [ ] (UMLS (ICD9CM) C0161158) =Injury or Poisoning
|
- 39. (S)-N,N'-bis(2-Hydroxy-1-(hydroxymethyl)ethyl)-2,4,6-triiodo-5-lactamidoisophthalamide
- [An organic iodine compound and used as a non-ionic water soluble radiographic contrast medium. Iopamidol blocks x-rays as they pass through the body, thereby allowing body structures not containing iodine to be visualized. The degree of opacity produced by iopamidol is directly proportional to the total amount of the iodinated contrast agent in the path of the x-rays. The visualization of body structures is dependent upon the distribution and elimination of iopamidol. (NCI05) ( NCI )] (UMLS (NCI) C0022026) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid =Triiodobenzoic Acids;
[DX101] NON-IONIC CONTRAST MEDIA =IOPAMIDOL 410 MG/ML;
IOPAMIDOL 510 MG/ML;
IOPAMIDOL 261 MG/ML;
IOPAMIDOL 612 MG/ML;
IOPAMIDOL 755 MG/ML;
IOPAMIDOL 408 MG/ML;
| - 89. 1ST DEG BURN GENITALIA
- [ ] (UMLS (ICD9CM) C0161113) =Injury or Poisoning
|
- 40. (S)-N,N,alpha-Trimethylphenethylamine
- (UMLS (NCI) C0058252) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 90. 1ST DEG BURN HAND NOS
- [ ] (UMLS (ICD9CM) C0274090) =Injury or Poisoning
|
- 41. (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide
- [inhibits tubulin-tubulin binding and thus destabilizes microtubules; used to block mitosis, axonal transport, and other microtubule dependent cellular functions in vitro, and clinically to treat gout. ( CSP )] (UMLS (NCI) C0009262) =Organic Chemical; Pharmacologic Substance ;
=alkaloid;
Antimitotic Agent;
[MS400] ANTIGOUT AGENTS;
cycloheptane =COLCHICINE 0.5 MG;
COLCHICINE 0.5 MG/ML;
COLCHICINE 0.6 MG;
COLCHICINE 0.65 MG | - 91. 1ST DEG BURN HAND-MULT
- [ ] (UMLS (ICD9CM) C0161220) =Injury or Poisoning
|
- 42. (S)-n1-[3-[(1-phenylethyl)amino]propyl]bleomycinamide
- [A semisynthetic analog of Bleomycin, a mixture of several basic glycopeptide antineoplastic antibiotics isolated from the fungus Streptomyces verticillus. Peplomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals that cause single- and double-stranded breaks in DNA. This agent appears to show greater antitumor activity than bleomycin; its use is limited due to pulmonary toxicity. (NCI04) ( NCI )] (UMLS (NCI) C0135981) =Amino Acid, Peptide, or Protein; Antibiotic ;
| - 92. 1ST DEG BURN HEAD NOS
- [ ] (UMLS (ICD9CM) C0273941) =Injury or Poisoning
|
- 43. (S)-Pyrrolidinecarbodithioic Acid
- (UMLS (NCI) C0084183) =Organic Chemical; Pharmacologic Substance
| - 93. 1ST DEG BURN HEAD-MULT
- [ ] (UMLS (ICD9CM) C0161054) =Injury or Poisoning
|
- 44. (S-(R*,R*))-1,2,3,4-butanetetrol,1,4-dimethanesulfonate
- [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0076959) =Organic Chemical; Pharmacologic Substance ;
| - 94. 1ST DEG BURN KNEE
- [ ] (UMLS (ICD9CM) C0161276) =Injury or Poisoning
|
- 45. (SP-4-2)-Diamminedichloroplatinum
- [inorganic, water soluble platinum complex; radiation sensitizing agent. ( CSP )] (UMLS (NCI) C0008838) =Pharmacologic Substance; Inorganic Chemical =[AN000] ANTINEOPLASTICS;
(SP-4-2)-Diamminedichloroplatinum;
Nitrogen Compounds;
Platinum Agents;
Chlorine Compounds;
=(SP-4-2)-Diamminedichloroplatinum;
(SP-4-2)-diammine[1,1-cyclobutanedicarboxylato(2--)-O,O']platinum;
CISPLATIN 0.5 MG/ML;
CISPLATIN 10 MG;
CISPLATIN 100 MG;
CISPLATIN 50 MG | - 95. 1ST DEG BURN LEG NOS
- [ ] (UMLS (ICD9CM) C0161271) =Injury or Poisoning
|
- 46. (SP-4-2)-diammine[1,1-cyclobutanedicarboxylato(2--)-O,O']platinum
- [organoplatinum compound with antineoplastic activity. ( CSP )] (UMLS (NCI) C0079083) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
(SP-4-2)-Diamminedichloroplatinum;
Organoplatinum Compounds;
=CARBOPLATIN 450 MG;
CARBOPLATIN 150 MG;
CARBOPLATIN 50 MG;
| - 96. 1ST DEG BURN LEG-MULT
- [ ] (UMLS (ICD9CM) C0161278) =Injury or Poisoning
|
- 47. *Saturation Fraction
- (UMLS (HL7) C1547041) =Quantitative Concept =Kind of quantity;
| - 97. 1ST DEG BURN LIP
- [ ] (UMLS (ICD9CM) C0161048) =Injury or Poisoning
|
- 48. *Substance Amount
- (UMLS (HL7) C1264637) =Quantitative Concept =Kind of quantity;
| - 98. 1ST DEG BURN LOWER LEG
- [ ] (UMLS (ICD9CM) C0161275) =Injury or Poisoning
|
- 49. *Substance Concentration
- (UMLS (HL7) C0457929) =Quantitative Concept =Kind of quantity;
| - 99. 1ST DEG BURN MULT FINGER
- [ ] (UMLS (ICD9CM) C0161215) =Injury or Poisoning
|
- 50. *Substance Concentration Increment
- (UMLS (HL7) C1264654) =Quantitative Concept =Kind of quantity;
| - 100. 1ST DEG BURN MULT SITE
- [ ] (UMLS (ICD9CM) C0161316) =Injury or Poisoning
|
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