UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
selected terms: 70,266 page 14 of 703

1301. 2ND DEG BURN BREAST
[ ] (UMLS (ICD9CM) C0840802) Blisters with epidermal loss due to burn [second degree] of breast =Injury or Poisoning
1351. 3 day report
(UMLS (HL7) C1546920) =Temporal Concept =Report timing;
1302. 2ND DEG BURN CHEST WALL
[ ] (UMLS (ICD9CM) C0161118) =Injury or Poisoning
1352. 3 DEG BRN W LOSS LEG-MLT
[ ] (UMLS (ICD9CM) C0161314) =Injury or Poisoning
1303. 2ND DEG BURN CHIN
[ ] (UMLS (ICD9CM) C0161060) =Injury or Poisoning
1353. 3 DEG BRN W LOSS-LEG NOS
[ ] (UMLS (ICD9CM) C0161307) =Injury or Poisoning
1304. 2ND DEG BURN EAR
[ ] (UMLS (ICD9CM) C0273948) =Injury or Poisoning
1354. 3 DEG BRN W LOSS-LOW LEG
[ ] (UMLS (ICD9CM) C0161311) =Injury or Poisoning
1305. 2ND DEG BURN ELBOW
[ ] (UMLS (ICD9CM) C0161168) =Injury or Poisoning
1355. 3 DEG BURN BACK OF HAND
[ ] (UMLS (ICD9CM) C0161238) =Injury or Poisoning
1306. 2ND DEG BURN EYE
[ ] (UMLS (ICD9CM) C0161058) =Injury or Poisoning
1356. 3 DEG BURN FINGR W THUMB
[ ] (UMLS (ICD9CM) C0161236) =Injury or Poisoning
1307. 2ND DEG BURN FACE NEC
[ ] (UMLS (ICD9CM) C0161063) =Injury or Poisoning
1357. 3 DEG BURN W LOSS-ANKLE
[ ] (UMLS (ICD9CM) C0161310) =Injury or Poisoning
1308. 2ND DEG BURN FINGER
[ ] (UMLS (ICD9CM) C0161223) =Injury or Poisoning
1358. 3 DEG BURN W LOSS-FOOT
[ ] (UMLS (ICD9CM) C0161309) =Injury or Poisoning
1309. 2ND DEG BURN FOOT
[ ] (UMLS (ICD9CM) C0161282) =Injury or Poisoning
1359. 3 DEG BURN W LOSS-KNEE
[ ] (UMLS (ICD9CM) C0161312) =Injury or Poisoning
1310. 2ND DEG BURN FOREARM
[ ] (UMLS (ICD9CM) C0161167) =Injury or Poisoning
1360. 3 DEG BURN W LOSS-THIGH
[ ] (UMLS (ICD9CM) C0161313) =Injury or Poisoning
1311. 2ND DEG BURN GENITALIA
[ ] (UMLS (ICD9CM) C0161121) =Injury or Poisoning
1361. 3 DEG BURN W LOSS-TOE
[ ] (UMLS (ICD9CM) C0375684) =Injury or Poisoning
1312. 2ND DEG BURN HAND NOS
[ ] (UMLS (ICD9CM) C0274133) =Injury or Poisoning
1362. 3 hours post challenge
(UMLS (HL7) C1547076) =Temporal Concept =Time delay post challenge;
1313. 2ND DEG BURN HAND-MULT
[ ] (UMLS (ICD9CM) C0161230) =Injury or Poisoning
1363. 3 methoxy 4 hydroxyphenylethyleneglycol
[metabolite of epinephrine and norepinephrine found in blood, brain, CSF, and urine, where it is used as a measure of catecholamine turnover. ( CSP )] (UMLS (CSP) C0025691) =Organic Chemical; Biologically Active Substance ;
=alcohol;
1314. 2ND DEG BURN HEAD NOS
[ ] (UMLS (ICD9CM) C0375674) =Injury or Poisoning
1364. 3 minutes post challenge
(UMLS (HL7) C1547078) =Temporal Concept =Time delay post challenge;
1315. 2ND DEG BURN HEAD-MULT
[ ] (UMLS (ICD9CM) C0161065) =Injury or Poisoning
1365. 3 months (90 days) post challenge
(UMLS (HL7) C1547077) =Temporal Concept =Time delay post challenge;
1316. 2ND DEG BURN KNEE
[ ] (UMLS (ICD9CM) C0161285) =Injury or Poisoning
1366. 3 Prime Repair Exonuclease 1
[TREX1 protein is phosphorylated by Ataxia Telangiectasia and Rad3 Related Protein (ATR), regulates ATR expression, and is an essential component of the DNA damage checkpoint pathway. TREX1 and ATR are mutually dependent partners in cell cycle checkpoint signaling pathways. The downstream ORF encodes isozymes that contain 3-prime-to-5-prime exonuclease activity and the excision of nucleotides from DNA 3-prime termini are required by DNA replication, repair, and recombination. They remove mismatched, modified, fragmented, and normal nucleotides to generate the appropriate 3-prime termini for subsequent steps in the DNA metabolic pathways. (NCI) ( NCI )] (UMLS (NCI) C0967200) ATR Interacting Protein;
ATR-Interacting Protein;
ATRIP;
Deoxyribonuclease III, DnaQ/MutD (E. coli)-Like;
DKFZp434J0310;
DNase III;
DRN3;
FLJ12343;
Three Prime Repair Exonuclease 1;
TREX1;
=Amino Acid, Peptide, or Protein; Enzyme ;
1317. 2ND DEG BURN LEG NOS
[ ] (UMLS (ICD9CM) C0161280) =Injury or Poisoning
1367. 3 Self-Sustaining Sequence Replication
[Molecular, 3 Self-Sustaining Sequence Replication ( HL7V3.0 )] (UMLS (HL7) C1553155) =Laboratory Procedure =ObservationMethod;
1318. 2ND DEG BURN LEG-MULT
[ ] (UMLS (ICD9CM) C0161287) =Injury or Poisoning
1368. 3' 5' exonuclease
[Three Prime-Five Prime Exonucleases prefer mismatched 3-prime termini, catalyze nucleoside monophosphate excision from 3-prime DNA termini and may be a DNA polymerase III subunit, which does not have intrinsic exonuclease activity. 3-prime terminal nucleotide excision from DNA is required to generate termini for subsequent DNA metabolic pathways. ( NCI )] (UMLS (CSP) C0950448) 3'-5' Exonuclease;
=Amino Acid, Peptide, or Protein; Enzyme
1319. 2ND DEG BURN LIP
[ ] (UMLS (ICD9CM) C0161059) =Injury or Poisoning
1369. 3' deoxyadenosine
[An anticancer drug that belongs to a family of drugs called antitumor antibiotics. ( NCI )] (UMLS (CSP) C0056331) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
1320. 2ND DEG BURN LOWER LEG
[ ] (UMLS (ICD9CM) C0161284) =Injury or Poisoning
1370. 3' exonuclease
[ ] (UMLS (CSP) C0075028) =Amino Acid, Peptide, or Protein; Enzyme ;
=exonuclease;
1321. 2ND DEG BURN MULT FINGER
[ ] (UMLS (ICD9CM) C0161225) =Injury or Poisoning
1371. 3' Untranslated Region
[Sequences on the 3' end of messenger RNAs that are not translated into protein. The 3'UTR is involved in many post-transcriptional regulatory pathways, including regulating translation efficiency, mRNA stability, and polyadenylation signals. ( NCI )] (UMLS (NCI) C0600600) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance
1322. 2ND DEG BURN MULT SITE
[ ] (UMLS (ICD9CM) C0161317) =Injury or Poisoning
1372. 3', 5'-Dichloroamethopterin
[A chlorinated methotrexate derivative. Dichloromethotrexate inhibits the enzyme dihydrofolate reductase, thereby preventing the synthesis of purine nucleotides and thymidylates and inhibiting DNA and RNA synthesis. This agent is metabolized and excreted by the liver. (NCI04) ( NCI )] (UMLS (NCI) C0046764) =Organic Chemical; Pharmacologic Substance
1323. 2ND DEG BURN NECK
[ ] (UMLS (ICD9CM) C0161064) =Injury or Poisoning
1373. 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine
[An anticancer drug that belongs to the family of plant drugs called vinca alkaloids. ( NCI )] (UMLS (NCI) C0078257) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
VINBLASTINE =NVB
1324. 2ND DEG BURN NOSE
[ ] (UMLS (ICD9CM) C0161061) =Injury or Poisoning
1374. 3'-Azido-3'-deoxythymidine
[synthetic thymidine analog that inhibits replication of some retroviruses, including human immunodeficiency virus; used in the management of AIDS or HIV infection. ( CSP )] (UMLS (NCI) C0043474) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM800] ANTIVIRALS;
Dideoxynucleosides;
dT;
2'3' dideoxynucleoside =ZIDOVUDINE 100 MG;
ZIDOVUDINE 300 MG;
ZIDOVUDINE 10 MG/ML
1325. 2ND DEG BURN PALM
[ ] (UMLS (ICD9CM) C0161227) =Injury or Poisoning
1375. 3'-C-Ethynylcytidine
(UMLS (NCI) C0533115) =Organic Chemical; Pharmacologic Substance
1326. 2ND DEG BURN SCALP
[ ] (UMLS (ICD9CM) C0161062) =Injury or Poisoning
1376. 3'-Deoxyadenosine-5'-(tetrahydrogen triphosphate)
[The triphosphate salt of Cordycepin, a purine nucleoside antimetabolite analogue and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic activity. Cordycepin incorporates into RNA, and, inhibits RNA chain elongation and synthesis due to the absence of a hydroxyl moiety at the 3' position. Because it is converted to an inactive metabolite by adenosine deaminase, this agent must be administered with an adenosine deaminase inhibitor in order to be effective. Cordycepin has displayed cytotoxicity against some leukemic cell lines in vitro. (NCI04) ( NCI )] (UMLS (NCI) C0046803) =Nucleic Acid, Nucleoside, or Nucleotide; Antibiotic
1327. 2ND DEG BURN SCAPULA
[ ] (UMLS (ICD9CM) C0161172) =Injury or Poisoning
1377. 3'5' cyclic nucleotide phosphodiesterase
[Enzymes that catalyze the hydrolysis of CYCLIC AMP to form adenosine 5'-phosphate. The enzymes are widely distributed in animal tissue and control the level of intracellular cyclic AMP. Many specific enzymes classified under this heading demonstrate additional spcificity for 3',5'-cyclic IMP and CYCLIC GMP. ( MSH )] (UMLS (CSP) C0000359) =Amino Acid, Peptide, or Protein; Enzyme ;
1328. 2ND DEG BURN SHOULDER
[ ] (UMLS (ICD9CM) C0161171) =Injury or Poisoning
1378. 3'5'-cyclic ester of AMP
[adenine nucleotide containing one phosphate group which is esterified to both the 3' and 5' positions of the sugar moiety; it is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones. ( CSP )] (UMLS (NCI) C0001455) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
1329. 2ND DEG BURN THIGH
[ ] (UMLS (ICD9CM) C0161286) =Injury or Poisoning
1379. 3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 17-(Acetyloxy)-6-chloro-1,2-dihydro-, (1beta,2beta)-
[A synthetic hormone being studied for treatment of hot flashes in men with prostate cancer who have had both testicles removed by surgery. ( NCI )] (UMLS (NCI) C0056855) =Steroid; Pharmacologic Substance
1330. 2ND DEG BURN THUMB
[ ] (UMLS (ICD9CM) C0161224) =Injury or Poisoning
1380. 3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, dichloride
[An dispiropiperazine derivative with potential cytostatic, anti-inflammatory and immune-suppressive properties. Although the exact mechanism of action of prospidin is not known, this agent was shown to interact with DNA, disrupting cell cycle at G2 phase, inhibiting phagocytic activity of monocytes and macrophage. Prospidin has good anti-lupus activity due to its immunosuppressive effects and was also used in refractory rheumatoid arthritis as an anti-rheumatic drug. (NCI04) ( NCI )] (UMLS (NCI) C0033524) =Organic Chemical; Pharmacologic Substance
1331. 2ND DEG BURN TOE
[ ] (UMLS (ICD9CM) C0161281) =Injury or Poisoning
1381. 3,3',4',5,7-Pentahydroxyflavone
(UMLS (NCI) C0910682) =Pharmacologic Substance ;
1332. 2ND DEG BURN TRUNK NEC
[ ] (UMLS (ICD9CM) C0161122) =Injury or Poisoning
1382. 3,3',5-triiodo-L-thyronine
[one of the thyroid hormones; an organic iodine containing compound secreted in small amounts by the thyroid gland; most circulating triiodothyroinine is produced by the deiodination of thyroxine in the peripheral tissues. ( CSP )] (UMLS (NCI) C0041014) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone =Thyroid Gland Hormone;
Thyronines;
3,3',5-triiodo-L-thyronine;
[HS851] THYROID SUPPLEMENTS =3,3',5-triiodo-L-thyronine;
LIOTHYRONINE SODIUM;
1333. 2ND DEG BURN TRUNK NOS
[ ] (UMLS (ICD9CM) C0840801) Blisters with epidermal loss due to burn [second degree] of unspecified site of trunk =Injury or Poisoning
1383. 3,3'-Azobis[6-hydroxybenzoic Acid]
[A prodrug of mesalamine (5-Aminosalicylic acid; 5-ASA) with anti-inflammatory activity. Unabsorbed olsalazine passes through gastrointestinal tract and is cleaved by azoreductases, produced by microflora in colon, into 2 active molecules of 5-ASA. 5-ASA exerts its anti-inflammatory action locally by inhibiting cyclooxygenase and lipoxygenase activities, thereby reducing the production of prostaglandins and leukotrienes. In addition, mesalamine may act as a scavenger of reactive oxygen free radicals. ( NCI )] (UMLS (NCI) C0069454) =Organic Chemical; Pharmacologic Substance ;
=Aminosalicylic Acids;
[GA900] GASTRIC MEDICATIONS, OTHER =Olsalazine Sodium;
1334. 2ND DEG BURN UPPER ARM
[ ] (UMLS (ICD9CM) C0161169) =Injury or Poisoning
1384. 3,3'-Diindolymethane
[A phytonutrient and plant indole found in cruciferous vegetables including broccoli, Brussels sprouts, cabbage, cauliflower and kale, with potential anti-androgenic and antineoplastic activities. As a dimer of indole-3-carbinol, diindolylmethane (DIM) promotes beneficial estrogen metabolism in both sexes by reducing the levels of 16-hydroxy estrogen metabolites and increasing the formation of 2-hydroxy estrogen metabolites, resulting in increased antioxidant activity. Although this agent induces apoptosis in tumor cells in vitro, the exact mechanism by which DIM exhibits its antineoplastic activity in vivo is unknown. ( NCI )] (UMLS (NCI) C1100708) 3,3'-Methylenebis-1H-indole;
CCRIS 5806;
Diindolylmethane;
=Organic Chemical; Pharmacologic Substance ;
1335. 2ND DEG BURN WRIST
[ ] (UMLS (ICD9CM) C1443011) Blisters with epidermal loss due to burn [second degree] of wrist;
=Injury or Poisoning ;
1385. 3,3'-Dimethoxybenzidine
[A colorless, highly toxic, crystalline compound that turns violet when exposed to air. Dianisidine is used exclusively as an intermediate for the production of dyes and pigments. Exposure to this substance causes skin irritation and sensitization. Dianisidine is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals. (NCI05) ( NCI )] (UMLS (NCI) C0011969) =Organic Chemical; Hazardous or Poisonous Substance ;
1336. 2ND DEGREE BURN NOS
[ ] (UMLS (ICD9CM) C0332687) =Injury or Poisoning
1386. 3,3'-Dimethyl-4,4'-biphenyldiamine
[A white to reddish colored, combustible, aromatic amine that emits toxic fumes of nitrogen oxides when heated to decomposition. o-Tolidine is used in industry as a dye or as an intermediate in the manufacture of dyes and pigments and is also used in clinical laboratories for the detection of blood. Exposure to this substance irritates the eyes, skin and respiratory tract and damages the kidneys and liver. o-Tolidine is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0046581) =Organic Chemical; Hazardous or Poisonous Substance
1337. 2ND DEGREE SUNBURN
[ ] (UMLS (ICD9CM) C0451998) =Injury or Poisoning
1387. 3,3'-Methylenebis(4-hydroxy-2H-1-benzopyran-2-one)
[An oral anticoagulant that interferes with the metabolism of vitamin K. It is also used in biochemical experiments as an inhibitor of reductases. ( MSH )] (UMLS (NCI) C0005640) =Organic Chemical; Pharmacologic Substance
1338. 2nd non-Operative
(UMLS (HL7) C1547205) =Idea or Concept =Procedure DRG Type;
1388. 3,3'-[(1,1'-Biphenyl)-4,4'-Diylbis(Azo)]Bis(5-Amino-4-Hydroxy)- 2,7-Naphthalenedisulfonic Acid, Tetrasodium Salt
[A Benzidine-based azo dye that is metabolized to free Benzidine in vivo. Direct blue 6 is primarily used for the dyeing of textiles, leather and paper. Benzidine and its metabolic derivatives have been detected in the urine of workers exposed to Benzidine-based dyes. Exposure to this dye is strongly associated with the occurrence of bladder cancer. (NCI05) ( NCI )] (UMLS (NCI) C0058439) =Organic Chemical; Pharmacologic Substance ;
1339. 2ND OP POST EYE REM NEC
[ ] (UMLS (ICD9CM) C0176302) =Therapeutic or Preventive Procedure
1389. 3,3-Dichloro-(1,1-Biphenyl)-4,4-Diamine
[A synthetic, light-sensitive, gray to purple crystalline solid that is insoluble in cold water but is soluble in ether, benzene, glacial acetic acid and alcohol. It is used primarily in the manufacture of pigments for printing ink, textiles, paper, paint, rubber, and plastics and as a curing agent for isocyanate-containing polymers and solid urethane plastics. When heated to decomposition, 3,3-dichlorobenzidine emits toxic fumes of chlorinated compounds and nitrogen oxides. The primary routes of potential human exposure to 3,3-dichlorobenzidine are inhalation of airborne dust, ingestion of contaminated well water by those living near hazardous waste sites, and dermal contact, primarily during industrial operations. Contact with this compound may cause dermatitis. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0000370) =Organic Chemical; Hazardous or Poisonous Substance ;
1340. 2nd Operative
(UMLS (HL7) C1547207) =Idea or Concept =Procedure DRG Type;
1390. 3,4 dihydroxyphenylacetate
[metabolite of DOPA. ( CSP )] (UMLS (CSP) C0178432) =Organic Chemical ;
=phenylacetate;
1341. 2NDRY EXENT CAVITY GRAFT
[ ] (UMLS (ICD9CM) C0176300) =Therapeutic or Preventive Procedure
1391. 3,4 methylenedioxyamphetamine
[abused, controlled, serotonergic hallucinogen of the "designer drug" class; probably the active metabolite of MDMA ("ecstasy"). ( CSP )] (UMLS (CSP) C0000379) =Organic Chemical; Pharmacologic Substance ;
1342. 2NDRY OCULAR IMP INSERT
[ ] (UMLS (ICD9CM) C0197003) =Therapeutic or Preventive Procedure
1392. 3,4 methylenedioxymethamphetamine
[synthetic adrenergic agonist resembling both amphetamine (a stimulant) and mescaline (a hallucinogen); "designer drug" once touted as potentially psychotherapeutic, but now a controlled substance considered a drug of abuse. ( CSP )] (UMLS (CSP) C0115471) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance =Amfetamine;
hallucinogen
1343. 2p
[Maxillary right second molar prosthesis ( HL7V3.0 )] (UMLS (HL7) C1552213) =Body Part, Organ, or Organ Component =Artificial dentition;
1393. 3,4,3',5'-Tetrahydroxy-trans-stilbene
(UMLS (NCI) C1176008) =Organic Chemical; Pharmacologic Substance
1344. 2pd
[Maxillary right second molar distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1552212) =Medical Device =Artificial dentition;
1394. 3,4,4'-Trichlorodiphenylurea
[A triclosan analogue with an antibacterial property. Triclocarban exerts its effect by inhibiting the activity of enoyl-(acyl-carrier protein) (ACP) reductase, widely distributed in bacteria, fungi and plants. ACP reductase catalyses the last step in each cycle of fatty acid elongation in the type II fatty acid synthase systems. As a result, this agent interupts cell membrane synthesis and leads to bacterial growth inhibition. ( NCI )] (UMLS (NCI) C0077072) =Organic Chemical; Pharmacologic Substance
1345. 2pm
[Maxillary right second molar mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1552214) =Medical Device =Artificial dentition;
1395. 3,4,5,6-Dibenzocarbazole
[A crystalline, carcinogenic aromatic hydrocarbon consisting of five fused rings and produced during the incomplete combustion of organic matter. 7H-Dibenzo[c,g]carbazole is primarily found in cigarette tar. This substance is used only for research purposes. 7H-Dibenzo[c,g]carbazole is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0049973) =Organic Chemical; Hazardous or Poisonous Substance
1346. 2PP2A
[Expressed by human SET Gene (NAP Family) in all tissues and responsive to serum factors, contact inhibition, or differentiation, 277-aa 32-kDa nuclear Phosphatase 2A Inhibitor I2PP2A is a specific inhibitor of PP2A that may be involved in intracellular signaling after ligand activation of HLA class II molecules. Serine phosphorylated SET has a long acidic C-terminus and SET domain. Located in an ER-associated complex containing pp32, HMG2, and APE1, SET is a specific inhibitor of GZMA-activated DNase/nucleoside diphosphate kinase (GAAD/NM23H1), which mediates GZMA-induced caspase-independent apoptosis characterized by single-stranded DNA nicks. GZMA cleavage of SET releases NM23H1 from bound inhibition to SET and results in SET degradation, NM23H1 translocation to the nucleus, and NM23H1 nicking of DNA. (NCI) ( NCI )] (UMLS (NCI) C1137947) HLA-DR Associated Protein II;
I2PP2A;
IGAAD;
Inhibitor of GZMA-Activated DNase;
PHAPII;
Phosphatase 2A Inhibitor I2PP2A;
SET;
SET Protein;
SET Translocation Inhibitor-2 of Protein Phosphatase-2A;
TAF-IBeta;
Template Activating Factor I Beta =Amino Acid, Peptide, or Protein; Biologically Active Substance
1396. 3,4,5-Trihydroxybenzoic Acid
(UMLS (NCI) C0885364) Gallic Acid =Organic Chemical ;
1347. 2s
[Supernumerary maxillary right second molar ( HL7V3.0 )] (UMLS (HL7) C1552116) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
1397. 3,4-Benzpyrene
[A crystalline, aromatic hydrocarbon consisting of five fused benzene rings and formed during the incomplete combustion of organic matter. 3,4-Benzpyrene is primarily found in gasoline and diesel exhaust, cigarette smoke, coal tar and coal tar pitch, charcoal-broiled foods and certain other foods, amino acids, fatty acids and carbohydrate pyrolysis products, soot smoke, creosote oil, petroleum asphalt and shale oils. This substance is used only for research purposes. 3,4-Benzpyrene is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0005052) =Organic Chemical; Hazardous or Poisonous Substance
1348. 2T- hours
(UMLS (HL7) C1547059) =Temporal Concept =Duration categories;
1398. 3,4-Dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione
[A naphthoquinone compound derived from bark of Tabebuia sp., with antitumor, antibacterial, antifungal and antitrypanosomal activities. Beta-lapachone exerts its anti-tumor effect by indirect actions of inducing p53-independent apoptosis and cell cycle arrest mediated through altered activities of cell cycle control regulatory proteins; including down-regulating retinoblastoma protein (pRB), a transcriptional repressor target at transcription factor E2F-1, as well as induces expression of cyclin dependent kinase inhibitor 1A (CDKN1A or p21). Both E2F-1 and p21 are required for G1/S-phase transition during cell cycle. This agent also inhibits DNA topoisomerase I by a mechanism distinct from that of camptothecin, and thereby blocks the formation of a cleavable complex leading to enzyme inhibition and prevent DNA repair. Furthermore, beta-lapachone could induce reactive oxygen species in vivo, and result in cytotoxicity. ( NCI )] (UMLS (NCI) C0053471) =Organic Chemical; Pharmacologic Substance ;
1349. 3
[Maxillary right first molar ( HL7V3.0 )] (UMLS (HL7) C0227034) tooth 3 =Body Part, Organ, or Organ Component =Permanent dentition;
1399. 3,4-Dihydro-2-amino-6-methyl-4-oxy-5-(4-pyridylthio)-quinazoline Dihydrochloride
[The hydrochloride salt form of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity. (NCI04) ( NCI )] (UMLS (NCI) C0389037) =Organic Chemical; Pharmacologic Substance
1350. 3
[A study to compare the results of people taking a new treatment with the results of people taking the standard treatment (for example, which group has better survival rates or fewer side effects). In most cases, studies move into phase III only after a treatment seems to work in phases I and II. Phase III trials may include hundreds of people. ( NCI )] (UMLS (NCI) C0282461) study III =Research Activity ;
=clinical trial;
1400. 3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide
[dacarbazine derivative; alkylating antineoplastic agent. ( CSP )] (UMLS (NCI) C0076080) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-;
Antineoplastic Alkylating Agent;
=TEMOZOLOMIDE 20 MG;
TEMOZOLOMIDE 100 MG;
TEMOZOLOMIDE 5 MG;
TEMOZOLOMIDE 250 MG;

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