- 1401. 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone
- [A benzophenone derivative and a catechol-O-methyltransferase (COMT) inhibitor. Tolcapone selectively and reversibly inhibits COMT, an enzyme that catalyzes the metabolism of biologically active catechols and their hydroxylated metabolites by transferring the methyl group of S-adenosyl-L-methionine to the phenolic group of catechol-containing substrates. When given in conjunction with a peripheral dopa decarboxylase inhibitor and levodopa, tolcapone may prevent the metabolism of levodopa to 3-methoxy-4-hydroxy- L-phenylalanine (3-OMD) in the brain and peripheral tissues leading to increased bioavailability and enhancement of delivery to the central nervous system (CNS) of levodopa. ( NCI )] (UMLS (NCI) C0246330) =Organic Chemical; Pharmacologic Substance ;
=[CN500] ANTIPARKINSON AGENTS;
Benzophenones =TOLCAPONE 100 MG;
TOLCAPONE 200 MG;
| - 1451. 3-hydroxymethyl-5-aziridinyl-1-methyl-2-(1H-indole-4,7-dione) prop-beta-en-alpha-ol
- [A bioreductive indoloquinone prodrug with potential antineoplastic and radiosensitizing activities. Apaziquone, an analogue of mitomycin C, becomes activated after being reduced by various reductases depending on tissue types. The activated metabolite and the reactive free radicals generated during reduction process cause DNA damages, thereby leading to induction of apoptosis. Furthermore, this agent displays cancer selectivity against both the hypoxic solid tumors, which exhibits higher expression of cytochrome P450 reductase, and also against the well-oxygenated malignant cells that overexpress the bioreductive enzyme NQO1 (NAD(P)H: quinone oxidoreductase). ( NCI )] (UMLS (NCI) C0095568) =Organic Chemical; Pharmacologic Substance ;
|
- 1402. 3,4-Dihydroxybenzohydroxamic acid
- [3,4-dihydroxybenzohydroxamic acid. An inhibitor of ribonucleotide reductase. ( NCI )] (UMLS (NCI) C0094556) =Organic Chemical; Pharmacologic Substance ;
| - 1452. 3-Isoxazolecarboxylic Acid, 5-methyl-, 2-(phenylmethyl)hydrazide
- [A hydralazine and monoamine oxidase (MAO) inhibitor with antidepressant activity. Isocarboxazid blocks the breakdown (oxidative deamination) of biogenic amines by inhibiting MAO, thereby increasing the concentrations of norepinephrine and 5-hydroxytrytamine (5-HT) at central aminergic receptors. These neurotransmitters are involved in sustaining mood and emotions. The down-regulation of central beta-adrenergic and serotonergic receptors by chronic inhibition of MAO may also contribute to the antidepressant effects seen by isocarboxazid. (NCI05) ( NCI )] (UMLS (NCI) C0022154) =Organic Chemical; Pharmacologic Substance ;
=isoxazole;
[CN602] MONOAMINE OXIDASE INHIBITOR ANTIDEPRESSANTS =ISOCARBOXAZID 10 MG;
|
- 1403. 3,4-Dihydroxyphenylethanol
- (UMLS (NCI) C0046981) =Organic Chemical; Pharmacologic Substance
| - 1453. 3-ketobutyrate
- [ ] (UMLS (CSP) C0220778) =Organic Chemical
|
- 1404. 3,5 cyclic AMP synthetase
- [An enzyme of the lyase class that catalyzes the formation of CYCLIC AMP and pyrophosphate from ATP. EC 4.6.1.1. ( MSH )] (UMLS (CSP) C0001492) =Amino Acid, Peptide, or Protein; Enzyme
| - 1454. 3-methyl TTNEB
- [An anticancer drug used to decrease the growth of some types of cancer cells. Also called bexarotene. ( NCI )] (UMLS (NCI) C0765273) 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic Acid;
Bexarotene;
BEXAROTENE PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Retinoic Acid Agent =BEXAROTENE 75 MG;
BEXAROTENE 1 % |
- 1405. 3,5-Bis(acetylamino)-2,4,6-triiodobenzoic Acid
- [A commonly used x-ray contrast medium. As DIATRIZOATE MEGLUMINE and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography. ( MSH )] (UMLS (NCI) C0012004) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
=[DX102] IONIC CONTRAST MEDIA;
=1-Deoxy-1-(methylamino)-D-glucitol 3,5-diacetamido-2,4,6-triiodobenzoate (salt);
3,5-Diacetamido-2,4,6-triiodobenzoic Acid, Sodium Salt | - 1455. 3-Methyl-7-chloro-1,2,4-benzothiadiazine 1,1-Dioxide
- [peripheral vasodilator that reduces blood pressure; diazoxide also has antidiuretic and hypoglycemic effects. ( CSP )] (UMLS (NCI) C0012022) =Organic Chemical; Pharmacologic Substance =antihypertensive agent;
benzothiadiazine;
[CV490] ANTIHYPERTENSIVES, OTHER;
thiazide;
[HS503] ANTIHYPOGLYCEMICS;
=DIAZOXIDE 15 MG/ML;
DIAZOXIDE 50 MG/ML;
DIAZOXIDE 50 MG;
|
- 1406. 3,5-Diacetamido-2,4,6-triiodobenzoic Acid, Sodium Salt
- [An iodinated radiopaque X-ray contrast medium. Diatrizoate sodium blocks X-rays, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not contain iodine and allowing visualization of these areas. This contrast agent is used as a diagnostic aid in angiography, urography and radiography. (NCI05) ( NCI )] (UMLS (NCI) C0012007) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid =3,5-Bis(acetylamino)-2,4,6-triiodobenzoic Acid;
1-Deoxy-1-(methylamino)-D-glucitol 3,5-diacetamido-2,4,6-triiodobenzoate (salt) =DIATRIZOATE NA PWDR,ORAL;
DIATRIZOATE SODIUM 80 MG/ML;
DIATRIZOATE SODIUM 100 MG;
DIATRIZOATE SODIUM 8 %;
DIATRIZOATE SODIUM 20 %;
DIATRIZOATE SODIUM 35 %;
DIATRIZOATE SODIUM 50 %;
DIATRIZOATE SODIUM 42 %;
DIATRIZOATE SODIUM 25 %;
DIATRIZOATE SODIUM 10 %;
DIATRIZOATE SODIUM 30 %;
DIATRIZOATE SODIUM 29.1 % | - 1456. 3-Methylglutaconyl-CoA Hydratase
- [AU-specific RNA-binding enoyl-CoA hydratase (AUH) protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. (LocusLink) ( NCI )] (UMLS (NCI) C0066377) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 1407. 3,5-Dibromo-N-(4-bromophenyl)-2-hydroxybenzamide
- [A salicylanilide derivative with antibacterial and antifungal activities banned by FDA due to its photosensitizing effect. Tribromsalan is used as disinfectant in medicated soaps. ( NCI )] (UMLS (NCI) C0077019) =Organic Chemical; Pharmacologic Substance ;
| - 1457. 3-Nitrobenzo[a]pyrene trans-7,8-Dihydrodiol
- (UMLS (NCI) C0768964) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 1408. 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl) pyridine
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0070220) =Organic Chemical; Pharmacologic Substance
| - 1458. 3-o-Chlorophenyl-5-methyl-4-isoxazolylpenicillin Sodium
- [The sodium salt form of cloxacillin, a semi-synthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity. Cloxacillin is bactericidal and binds to specific penicillin-binding proteins on the bacterium and inhibits the transpeptidation enzyme, thereby preventing the cross-linking of peptidoglycans. This leads to an interruption of the bacterial cell wall and causes bacterial lysis. Cloxacillin is active against beta-lactamase producing staphylococci. ( NCI )] (UMLS (NCI) C0037496) =Organic Chemical; Antibiotic ;
=CLOXACILLIN;
=CLOXACILLIN SODIUM 250 MG;
CLOXACILLIN SODIUM 500 MG |
- 1409. 3,5-Pyrazolidinedione, 1,2-diphenyl-4-(2-(phenylsulfinyl)ethyl)-
- [A phenylbutazone derivative with uricosuric and antithrombotic properties. Sulfinpyrazone competitively inhibits reabsorption of urate at the proximal renal tubule in the kidney. This agent acts on the organic anion transport exchanger, thereby increasing uric acid excretion and decreasing serum uric acid levels resulting in the prevention of urate deposition. Sulfinpyrazone also blocks tubular excretion of various acidic drugs, resulting in increased serum concentration of the drugs. In addition, sulfinpyrazone and its active metabolite inhibit the synthesis of thromboxane A2, by competitively inhibiting the activity of cyclooxygenase, thereby preventing platelet aggregation through restoration of platelet survival time to normal, and decreasing platelet adhesiveness to subendothelial cells. ( NCI )] (UMLS (NCI) C0038742) =Organic Chemical; Pharmacologic Substance ;
=[MS400] ANTIGOUT AGENTS;
PHENYLBUTAZONE =SULFINPYRAZONE 100 MG;
SULFINPYRAZONE 200 MG | - 1459. 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2
- [catalyzes the reduction of testosterone to 5 alphadihydrotestosterone. ( CSP )] (UMLS (NCI) C0039602) =Amino Acid, Peptide, or Protein; Enzyme ;
=hydrocarbon oxidoreductase;
|
- 1410. 3,5-Pyridinedicarboxylic Acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, Methyl 1-methylethyl Ester
- [A dihydropyridine calcium channel blockers with antihypertensive and vasodilator activity. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vascular smooth muscle, thereby dilating coronary arteries and peripheral arterioles. This increases oxygen delivery due to an increased blood flow and reduces oxygen requirements due to decrease in total peripheral resistance. (NCI05) ( NCI )] (UMLS (NCI) C0071304) =Organic Chemical; Pharmacologic Substance ;
=[CV200] CALCIUM CHANNEL BLOCKERS;
Dihydropyridines;
[CV250] ANTIANGINALS;
=ISRADIPINE 2.5 MG;
ISRADIPINE 5 MG;
ISRADIPINE 10 MG | - 1460. 3-oxobutyrate
- [ ] (UMLS (CSP) C1536988) =Organic Chemical
|
- 1411. 3,6-bis-(2-piperidinoethoxyl)acridine trihydrochloride
- (UMLS (NCI) C0055843) =Organic Chemical; Pharmacologic Substance ;
| - 1461. 3-Phenyl-1H-naphtho[2,1-b]pyran-1-one
- [A polycyclic aromatic hydrocarbon that consists of a flavone group attached to a benzene ring. Beta-naphthoflavone is an inducer of the hepatic cytochrome p450 CYP1A1 and CYP1A2. ( NCI )] (UMLS (NCI) C0053490) =Organic Chemical; Pharmacologic Substance ;
|
- 1412. 3,6-Dinitro-2-phenyl-4H-1-benzopyran-4-one
- (UMLS (NCI) C0538186) =Organic Chemical; Pharmacologic Substance ;
| - 1462. 3-Phenylacetylamino-2, 6-piperidinedione
- [A piperidinedione antineoplaston with potential antineoplastic activity. Antineoplaston A10 was originally isolated from human urine but is now synthetically derived. This agent intercalates into DNA, resulting in cell cycle arrest in G1 phase, reduction of mitosis, and decreased protein synthesis. Antineoplaston A10 may also inhibit ras-oncogene expression and activate tumor suppressor gene p53, leading to cell differentiation and apoptosis. (NCI04) ( NCI )] (UMLS (NCI) C0052080) =Organic Chemical; Pharmacologic Substance ;
|
- 1413. 3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic Acid
- [Porphyrins with four methyl, two vinyl, and two propionic acid side chains attached to the pyrrole rings. Protoporphyrin IX occurs in hemoglobin, myoglobin, and most of the cytochromes. ( MSH )] (UMLS (NCI) C0033733) =Organic Chemical; Biologically Active Substance
| - 1463. 3-Phosphoinositide Dependent Protein Kinase-1
- [3-Phosphoinositide Dependent Protein Kinase-1, encoded by the PDPK1 gene, belongs to the Ser/Thr family of protein kinases. This protein phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, p70S6K and p90S6K/RSK. It may play a general role in signaling processes and in development (by similarity). It becomes cytoplasmic and membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane. Three isoforms exist from alternative splicing and Isoform 3 is catalytically inactive. (from LocusLink) ( NCI )] (UMLS (NCI) C0541150) =Amino Acid, Peptide, or Protein; Enzyme
|
- 1414. 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- [1,3-dimethylxanthine; methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. ( CSP )] (UMLS (NCI) C0039771) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =bronchodilator;
Xanthine Alkaloids;
xanthine;
Muscle Relaxant;
methylpurine;
[RE104] BRONCHODILATORS, XANTHINE-DERIVATIVE =1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compound with 1,2-Ethanediamine(2:1);
DIMENHYDRINATE;
1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl;
Choline, hydroxide, compound with Theophylline(1:1);
pamabrom;
Theophylline Anhydrous;
THEOPHYLLINE CALCIUM SALICYLATE;
THEOPHYLLINE SODIUM GLYCINATE;
THEOPHYLLINE CALCIUM SALICYLATE;
THEOPHYLLINE SODIUM GLYCINATE;
THEOPHYLLINE 0.4 MG/ML;
THEOPHYLLINE 0.8 MG/ML;
Theophylline 10 MG/ML;
THEOPHYLLINE 100 MG;
THEOPHYLLINE 120 MG;
THEOPHYLLINE 125 MG;
THEOPHYLLINE 2 MG/ML;
THEOPHYLLINE 250 MG;
THEOPHYLLINE 3.2 MG/ML;
THEOPHYLLINE 300 MG;
THEOPHYLLINE 4 MG/ML;
THEOPHYLLINE 450 MG;
THEOPHYLLINE 600 MG;
THEOPHYLLINE 1.6 MG/ML;
THEOPHYLLINE 200 MG;
THEOPHYLLINE 400 MG;
THEOPHYLLINE 100 MG/18.75ML;
THEOPHYLLINE 100 MG/15ML;
Theophylline 10.7 MG/ML;
Theophylline 5.9 MG/ML;
THEOPHYLLINE SODIUMGLYCINATE;
THEOPHYLLINE 80 MG/15ML;
| - 1464. 3-Phosphoinositide Dependent Protein Kinase-1 Gene
- [This gene plays a role in cellular signaling and development. ( NCI )] (UMLS (NCI) C1335204) PDPK1;
PDPK1 Gene =Gene or Genome |
- 1415. 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
- [metabolite of pentifylline (a preparation of theobromine and hexyl halide); used as a vasodilator. ( CSP )] (UMLS (NCI) C0030899) =Organic Chemical; Pharmacologic Substance ;
=theobromine;
Vasodilating Agent;
[CV900] CARDIOVASCULAR AGENTS, OTHER;
=PENTOXIFYLLINE 400 MG;
| - 1465. 3-Pyridinecarboxamide
- [B complex vitamin used in the prophylaxis and treatment of pellagra; functions as a component of the coenzyme NAD (Nicotinamide-Adenine Dinucleotide). ( CSP )] (UMLS (NCI) C0028027) =Organic Chemical; Pharmacologic Substance; Vitamin =[VT103] NICOTINIC ACID;
3-Pyridinecarboxamide;
Nicotinic Acids;
[VT100] VITAMIN B;
TO BE DELETED INGREDIENT PREPARATIONS;
Unclassified Ingredient Preparations =3-Pyridinecarboxamide;
NICOTINAMIDE HYDRIODIDE;
NIACIN (AS NIACINAMIDE) 28 MG/L;
NIACIN (AS NIACINAMIDE) 3.33 MG;
NIACIN (AS NIACINAMIDE) 30 MG;
CITROTEIN POWDER (ORANGE);
MERITENE POWDER (CHOCOLATE);
MERITENE POWDER (MILK More… |
- 1416. 3,7-Dimethyl-9-(2,6, 6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
- [Vitamin A. It is essential for proper vision and healthy skin and mucous membranes. Retinol is being studied for cancer prevention; it belongs to the family of drugs called retinoids. ( NCI )] (UMLS (NCI) C0087161) =Organic Chemical; Pharmacologic Substance; Vitamin =Retinoic Acid Agent;
| - 1466. 3-Tritylthio-L-Alanine
- [A derivative of cysteine with antimitotic activity and potential antineoplastic activity. (NCI04) ( NCI )] (UMLS (NCI) C0601886) =Amino Acid, Peptide, or Protein ;
|
- 1417. 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-trans-4-trans-6-cis-8-trans-nonatetraenoic Acid
- [A drug being studied for cancer prevention. It belongs to the family of drugs called retinoids. ( NCI )] (UMLS (NCI) C0281666) =Organic Chemical; Pharmacologic Substance; Vitamin =(All-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid;
[DE600] ANTINEOPLASTICS, TOPICAL =ALITRETINOIN 0.1 % | - 1467. 3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinone
- (UMLS (NCI) C0538429) =Organic Chemical; Pharmacologic Substance
|
- 1418. 3-(((Dimethylamino)carbonyl)oxy)-1-methylpyridinium Bromide
- [The bromide salt form of pyridostigmine, a quaternary ammonium carbamate derivative and a acetylcholinesterase inhibitor. Pyridostigmine bromide binds reversibly to acetylcholinesterase active sites in the peripheral nervous system, thereby preventing the breakdown of acetylcholine. This leads to an accumulation of acetylcholine at cholinergic synapses and facilitates transmission of impulses across the neuromuscular junction. Mediated through muscarinic receptors, this agent increases contraction of bronchial and intestinal smooth muscle and the exocrine glands secretions, while it causes paralysis of the skeletal muscles mediated through nicotinic receptors . In addition, pyridostigmine is used as a reversible blocking agent to prevent organophosphates from binding to the acetylcholinesterase receptors and thereby protect the nervous system from the effects of nerve agents such as Soman. ( NCI )] (UMLS (NCI) C0034262) =Organic Chemical; Pharmacologic Substance ;
=Pyridinium Compounds;
PYRIDOSTIGMINE =PYRIDOSTIGMINE BROMIDE 180 MG;
PYRIDOSTIGMINE BROMIDE 5 MG/ML;
PYRIDOSTIGMINE BROMIDE 60 MG;
PYRIDOSTIGMINE BROMIDE 60 MG/5ML;
| - 1468. 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione
- [3-(2-(4-(p-fluorobenzoyl)-piperidino) ethyl)-2,4-quinazolinedione. ( CSP )] (UMLS (NCI) C0022616) =Organic Chemical; Pharmacologic Substance =quinazoline;
serotonin inhibitor |
- 1419. 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m-ethylthiazolium Chloride, Monohydrochloride
- [The hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, thiamine hydrochloride is phosphorylated by thiamine diphosphokinase to form active thiamine pyrophosphate (TPP), also known as cocarboxylase. TPP is an coenzyme for many enzymatic activities involving fatty acid, amino acid and carbohydrate metabolism. ( NCI )] (UMLS (NCI) C0770309) THIAMINE HYDROCHLORIDE;
THIAMINE HYDROCHLORIDE PREPARATION;
Vitamin B1 Hydrochloride =Organic Chemical; Pharmacologic Substance; Vitamin =[VT105] THIAMINE;
=CRITICARE HN LIQUID;
LONALAC POWDER,ORAL;
MERITENE More… | - 1469. 3-[[(R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]indole, Monohydrobromide
- [A triptan with specific affinity for the 5-hydroxytriptamine1B/1D receptor. Eletriptan hydrobromide binds to and acts at serotonin 5-HT1B receptors located on intracranial blood vessels which leads to vasoconstriction. This drug may also exerts its effects by binding to and activating 5-HT 1D receptors on sensory nerve endings in the trigeminal system, which results in the inhibition of pro-inflammatory neuropeptide release. Eletriptan hydrobromide is used to relieve pain or symptoms associated with migraine headaches. ( NCI )] (UMLS (NCI) C1178489) ELETRIPTAN HYDROBROMIDE;
ELETRIPTAN HYDROBROMIDE UNIDENTIFIED =Organic Chemical; Pharmacologic Substance |
- 1420. 3-(2,5-Dihydroxyphenyl)-2-propenoic Acid Methyl Ester
- [A cell-permeable analog of erbstatin, a compound isolated from Streptomyces that inhibits the autophosphorylation of epidermal growth factor receptor. Erbstatin analogue competitively inhibits epidermal growth factor receptor-associated tyrosine kinase, inhibiting the activation of v-abl tyrosine kinase. In addition, this agent has induced apoptosis in mouse thymocytes and inhibits the G2/M phase of the cell cycle. (NCI) ( NCI )] (UMLS (NCI) C0083406) =Organic Chemical; Pharmacologic Substance
| - 1470. 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
- [A flavonol glycoside found in many plants, including BUCKWHEAT; TOBACCO; FORSYTHIA; HYDRANGEA; VIOLA, etc. It has been used therapeutically to decrease capillary fragility. ( MSH )] (UMLS (NCI) C0035976) =Organic Chemical; Pharmacologic Substance ;
=Bioflavonoid;
Inactive Ingredient Preparations =RUTIN 50 MG |
- 1421. 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl Penicillin Sodium Monohydrate
- [The sodium salt form of dicloxacillin, a broad-spectrum, semi-synthetic beta-lactam with bactericidal and beta-lactamase resistant activity. Dicloxacillin sodium binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall. It also inhibits the cross-linkage of peptidoglycan, a critical component of bacterial cell walls. This leads to the inhibition of bacterial cell wall synthesis and eventually causes cell lysis. ( NCI )] (UMLS (NCI) C0887422) DICLOXACILLIN SODIUM;
DICLOXACILLIN SODIUM PREPARATION =Organic Chemical; Antibiotic ;
=3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin;
=DICLOXACILLIN SODIUM 250 MG;
DICLOXACILLIN SODIUM 500 MG;
DICLOXACILLIN SODIUM 62.5 MG/5ML | - 1471. 3.2% Citrate
- (UMLS (HL7) C1550056) =Organic Chemical; Biomedical or Dental Material =Additive/Preservative;
|
- 1422. 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin
- [A broad-spectrum, semi-synthetic, beta-lactam, penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Dicloxacillin binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall. It also inhibits the cross-linkage of peptidoglycan, a critical component of bacterial cell walls. This leads to the inhibition of bacterial cell wall synthesis and eventually causes cell lysis. ( NCI )] (UMLS (NCI) C0012093) =Organic Chemical; Antibiotic =CLOXACILLIN;
[AM053] PENICILLINASE-RESISTANT PENICILLINS =3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl Penicillin Sodium Monohydrate;
| - 1472. 3.2% Citrate
- [A 3.2% solution of Sodium Citrate in water. Used as a blood preservative ( HL7V3.0 )] (UMLS (HL7) C1561458) =Intellectual Product =MaterialEntityAdditive;
|
- 1423. 3-(2-Dimethylamino)ethylindol-4-ol Dihydrogen Phosphate
- [A tryptamine alkaloid, isolated from fungi of the genus Psilocybe with hallucinogenic, anxiolytic and psychoactive activities. Psilocybin is converted by phosphatases in vivo into the active compound psilocin. Psilocin exerts its effect by binding to and activating serotonin 2A (5-HT2A) and 1A (5-HT1A) receptors in the central nervous system, thereby mimicking the effects of serotonin. ( NCI )] (UMLS (NCI) C0033850) =Organic Chemical; Pharmacologic Substance
| - 1473. 3.8% Citrate
- (UMLS (HL7) C1550057) =Organic Chemical; Biomedical or Dental Material =Additive/Preservative;
|
- 1424. 3-(3-Hydroxyanthraniloyl)alanine
- (UMLS (NCI) C0047472) =Organic Chemical; Pharmacologic Substance ;
| - 1474. 3.8% Citrate
- [A 3.8% solution of Sodium Citrate in water. Used as a blood preservative ( HL7V3.0 )] (UMLS (HL7) C1561459) =Intellectual Product =MaterialEntityAdditive;
|
- 1425. 3-(4-(1-formylpiperazin-4-yl)-benzylidenyl)-2-indolinone
- (UMLS (NCI) C0538432) =Organic Chemical; Pharmacologic Substance
| - 1475. 3.Alpha,4.Beta, 15-triol, 12, 13-epoxy-,4, 15-diacetate (8CI)
- [trichothecene mycotoxin produced by species of Fusarium that contaminate grain and other foodstuffs, causing fusariotoxicosis and hemorrhaging in livestock. ( CSP )] (UMLS (NCI) C0057671) =Organic Chemical; Pharmacologic Substance ;
=Fungal Toxin;
sesquiterpene |
- 1426. 3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol
- [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called signal transduction inhibitors. ( NCI )] (UMLS (NCI) C1134444) NV-06;
Phenoxodiol;
=Organic Chemical; Pharmacologic Substance | - 1476. 30
- [The first, permanent, six-year molar of the lower right arch as defined by the Universal tooth numbering system. ( NCI )] (UMLS (HL7) C0227073) tooth 30 =Body Part, Organ, or Organ Component =Permanent dentition;
|
- 1427. 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1h-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-2-propenamide
- [A pyrrolo(1,4)benzodiazepine antineoplastic antibiotic isolated from the bacterium Streptomyces refuineus var. thermotolerans. Anthramycin binds covalently to guanine in the minor groove of DNA, thereby inhibiting DNA replication and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0003167) =Organic Chemical; Antibiotic
| - 1477. 30 day report
- (UMLS (HL7) C1546919) =Temporal Concept =Report timing;
|
- 1428. 3-(Aminocarbonyl)-O4-deacetyl-3-de-(methoxycarbonyl)vincaleukoblastine
- [An anticancer drug that belongs to the family of plant drugs called vinca alkaloids. ( NCI )] (UMLS (NCI) C0042682) =Organic Chemical; Pharmacologic Substance ;
| - 1478. 30 minutes post challenge
- (UMLS (HL7) C1547075) =Temporal Concept =Time delay post challenge;
|
- 1429. 3-(Aminomethyl)-5-methyl-hexanoic Acid
- [A 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic and analgesic activities. Pregabalin selectively binds to alpha2delta (A2D) subunit of the presynaptic voltage-gated calcium channels located in the central nervous system (CNS). Binding of A2D subunits prevent calcium influxes and the subsequent calcium-dependent releases of various neurotransmitters from presynaptic nerve terminals in hyperexcited neurons, including glutamate, norepinephrine, serotonin, dopamine, and substance P. This leads to an inhibition of synaptic transmission and reduces neuronal excitability. Pregabalin does not bind directly to GABA-A, GABA-B receptors and does not alter GABA uptake or degradation. ( NCI )] (UMLS (NCI) C0657912) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
| - 1479. 30-39% BDY BRN/10-19% 3D
- [ ] (UMLS (ICD9CM) C0161338) =Injury or Poisoning
|
- 1430. 3-(Hydroxynitrosoamino)-L-alanine
- [An amino acid analog derived from Streptomyces alanosinicus, a purine antagonist, and an adenylosuccinate synthase inhibitor with antineoplastic properties. L-alanosine deprives MTAP-deficient (salvage pathway) tumor cells of de novo synthesized adenosine and is probably responsible for diminished DNA synthesis. The clinical use of L-alanosine may be narrow due to its toxicity profile. (NCI04) ( NCI )] (UMLS (NCI) C0051066) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 1480. 30-39% BDY BRN/20-29% 3D
- [ ] (UMLS (ICD9CM) C0161339) =Injury or Poisoning
|
- 1431. 3-(Methylseleno)-l-alanine
- (UMLS (NCI) C0074299) =Organic Chemical; Pharmacologic Substance ;
| - 1481. 30-39% BDY BRN/3 DEG NOS
- [ ] (UMLS (ICD9CM) C0161337) =Injury or Poisoning
|
- 1432. 3-(o-Methoxyphenoxy)-1,2-propanediol
- [A glyceryl guaiacolate with expectorant effects. Guaifenesin increases respiratory tract mucus secretions, acts as an irritant to gastric vagal receptors and recruits efferent parasympathetic reflexes that cause glandular exocytosis. This agent reduces the viscosity of mucus secretion by reducing adhesiveness and surface tension as well as increasing hydration of mucus. Guaifenesin promotes the efficiency of the mucociliary mechanism important in removing accumulated secretions from the upper and lower airway. ( NCI )] (UMLS (NCI) C0018305) =Organic Chemical; Pharmacologic Substance =Guaiacol;
[RE400] MUCOLYTICS;
[RE302] NON-OPIOID-CONTAINING ANTITUSSIVES/EXPECTORANTS;
=METHOCARBAMOL;
Guaifenesin 10 MG/ML;
GUAIFENESIN 1200 MG;
Guaifenesin 13.4 MG/ML;
Guaifenesin 17 MG/ML;
GUAIFENESIN 100 MG/5ML;
GUAIFENESIN 250 MG;
GUAIFENESIN 150 MG/5ML;
GUAIFENESIN 200 MG/5ML;
GUAIFENESIN 400 MG;
GUAIFENESIN 25 MG/5ML;
GUAIFENESIN 50 MG;
GUAIFENESIN 250 MG/5ML;
GUAIFENESIN 500 MG;
GUAIFENESIN 600 MG;
GUAIFENESIN 125 MG;
Guaifenesin 15 MG/ML;
GUAIFENESIN 200 MG;
GUAIFENESIN 300 MG;
Guaifenesin 6 MG/ML;
GUAIFENESIN 100 MG;
GUAIFENESIN 800 MG;
GUAIFENESIN 100 MG/15ML;
GUAIFENESIN 575 MG;
Guaifenesin 13.3 MG/ML;
GUAIFENESIN 150 MG;
GUAIFENESIN 75 MG | - 1482. 30-39% BDY BRN/30-39% 3D
- [ ] (UMLS (ICD9CM) C0161340) =Injury or Poisoning
|
- 1433. 3-(p-(bis(2-chloroethyl)amino)phenyl)-L-Alanine, Hydrochloride
- [A bifunctional alkylating agent and phenylalanine derivative of nitrogen mustard. Melphalan hydrochloride is converted into highly reactive ethylenimmonium intermediates that induce covalent guanine N7-N7 intra- and inter-crosslinks and alkylation of adenine N3 of DNA. This agent also alkylates RNA and protein structures. As a result RNA transcription and protein synthesis are inhibited, ultimately leading to cell growth arrest and/or death. ( NCI )] (UMLS (NCI) C0771055) Melphalan Hydrochloride;
MELPHALAN HYDROCHLORIDE PREPARATION =Organic Chemical; Pharmacologic Substance =4-[bis(2-chloroethyl)amino]-L-phenylalanine;
=MELPHALAN HYDROCHLORIDE 50 MG;
| - 1483. 309 F
- (UMLS (NCI) C0878169) Fourneau 309 =Organic Chemical; Pharmacologic Substance
|
- 1434. 3-ABaP
- [A polycyclic aromatic hydrocarbon belongs to the family of mutagen benzo(a)pyrene. 3-aminobenzo(a)pyrene consists of five fused rings with an amino-group attached to the third carbon atom of the aromatic hydrocarbon ring with potential carcinogenicity. ( NCI )] (UMLS (NCI) C0768968) 3-Aminobenzo[a]pyrene;
=Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance | - 1484. 30a
- [Mandibular right first molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553668) =Medical Device =Artificial dentition;
|
- 1435. 3-Amino-1,2,4-benzotriazine-1,4-dioxide
- [antineoplastic, radiation sensitizing agent; 3-amino1,2,4-benzotriazine 1,4-dioxide. ( CSP )] (UMLS (NCI) C0208407) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Radiation Sensitizers;
triazine;
| - 1485. 30ad
- [Mandibular right first molar abutment distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1553670) =Medical Device =Artificial dentition;
|
- 1436. 3-Amino-1-[4-(2 amino-1H-imidazolyl]-propanol, 2HCl
- [A compound isolated from the marine sponge Pseudaxinyssa cantharella exhibiting anti-tumor activity. Studies indicate girodazole acts during the elongation/termination steps of protein synthesis, resulting in protein synthesis inhibition. (NCI) ( NCI )] (UMLS (NCI) C0119196) =Organic Chemical; Pharmacologic Substance
| - 1486. 30am
- [Mandibular right first molar abutment mesial hemisection ( HL7V3.0 )] (UMLS (HL7) C1553669) =Medical Device =Artificial dentition;
|
- 1437. 3-Aminopyridine-2-carboxaldehyde Thiosemicarbazone
- [3-aminopyridine-2-carboxaldehyde thiosemicarbazone. A substance that is being studied as an anticancer drug. It belongs to the family of drugs called ribonucleotide reductase inhibitors. ( NCI )] (UMLS (NCI) C0210403) =Organic Chemical; Pharmacologic Substance ;
| - 1487. 30d
- [Mandibular right first molar distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1552110) =Body Part, Organ, or Organ Component =Permanent dentition;
|
- 1438. 3-AP/Cisplatin/Paclitaxel
- (UMLS (NCI) C0935830) =Therapeutic or Preventive Procedure
| - 1488. 30i
- [Mandibular right first molar implant ( HL7V3.0 )] (UMLS (HL7) C1552200) =Medical Device =Artificial dentition;
|
- 1439. 3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine
- [A tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters. This drug also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which are responsible for the many side effects seen with this agent. ( NCI )] (UMLS (NCI) C0009010) =Organic Chemical; Pharmacologic Substance ;
=[CN601] TRICYCLIC ANTIDEPRESSANTS;
Dibenzazepines =3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine monohydrochloride;
| - 1489. 30id
- [Mandibular right first molar implant distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1552202) =Medical Device =Artificial dentition;
|
- 1440. 3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine monohydrochloride
- [The hydrochloride salt form of clomipramine, a tertiary amine salt derivative of dibenzazepine. Clomipramine hydrochloride is a tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters. This drug also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which are responsible for the many side effects seen with this agent. ( NCI )] (UMLS (NCI) C0282107) =Organic Chemical; Pharmacologic Substance ;
=3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine;
=CLOMIPRAMINE HYDROCHLORIDE 25 MG;
CLOMIPRAMINE HYDROCHLORIDE 50 MG;
CLOMIPRAMINE HYDROCHLORIDE 75 MG | - 1490. 30im
- [Mandibular right first molar implant mesial hemisection ( HL7V3.0 )] (UMLS (HL7) C1552201) =Medical Device =Artificial dentition;
|
- 1441. 3-Chloroprocainamide
- [A third-generation DNA repair inhibitor that modulates multi-drug resistance. ( NCI )] (UMLS (NCI) C0649622) =Organic Chemical
| - 1491. 30m
- [Mandibular right first molar mesial hemisection ( HL7V3.0 )] (UMLS (HL7) C1552109) =Body Part, Organ, or Organ Component =Permanent dentition;
|
- 1442. 3-Deazaguanine
- [A purine nucleoside analogue with antineoplastic and antiviral activity. By replacing guanine, dezaguanine incorporates into DNA and inhibits de novo purine synthesis, thereby inducing cell death. (NCI) ( NCI )] (UMLS (NCI) C0047332) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 1492. 30p
- [Mandibular right first molar prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553625) =Medical Device =Artificial dentition;
|
- 1443. 3-Ethyl-3-methylpyrrolidine-2,5-dione
- [A succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures. ( NCI )] (UMLS (NCI) C0015043) =Organic Chemical; Pharmacologic Substance ;
=[CN400] ANTICONVULSANTS;
succinimide =ETHOSUXIMIDE 250 MG;
ETHOSUXIMIDE 250 MG/5ML;
| - 1493. 30pd
- [Mandibular right first molar distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553626) =Medical Device =Artificial dentition;
|
- 1444. 3-ethyl-5-phenyl-2,4-imidazolidinedione
- [A hydantoin anticonvulsant with anti-epileptic activity. The mechanism of action is not completely known, but is thought to be fairly similar to phenytoin. Ethotoin influences synaptic transmission by altering sodium and calcium ion influx across neuronal membranes in the repolarization, depolarization, and membrane stability phase and interferes with the calcium uptake in presynaptic terminals. This inhibits neuronal firing and results in the stabilization of neuronal membranes, thereby preventing the spread of seizure activity at the motor cortex. ( NCI )] (UMLS (NCI) C0015046) =Organic Chemical; Pharmacologic Substance ;
=[CN400] ANTICONVULSANTS;
hydantoin =ETHOTOIN 250 MG;
ETHOTOIN 500 MG;
| - 1494. 30pm
- [Mandibular right first molar mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553624) =Medical Device =Artificial dentition;
|
- 1445. 3-Heptanol, 6-(dimethylamino)-4,4-diphenyl-, Acetate (Ester), (3S,6S)-(-)-
- [The hydrochloride salt form of levomethadyl acetate, a synthetic mu-receptor agonist with analgesic activity. Levomethadyl acetate hydrochloride mimics the actions of endogenous peptides at CNS opioid receptors, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. Levomethadyl acetate hydrochloride has less severe withdrawal symptoms compared to the morphine-like agents. In addition, with chronic use, levomethadyl acetate hydrochloride produces cross-tolerance to the effects of other mu-receptor agonists, thereby decreasing the physical dependence. ( NCI )] (UMLS (NCI) C0282232) =Organic Chemical; Pharmacologic Substance ;
=LEVOMETHADYL;
=LEVOMETHADYL ACETATE HYDROCHLORIDE 10 MG/ML | - 1495. 30s
- [Supernumerary mandibular right first molar ( HL7V3.0 )] (UMLS (HL7) C1552144) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 1446. 3-Hydroxy-2-phenyl-4H-1-benzopyran-4-one
- (UMLS (NCI) C0284815) =Organic Chemical; Pharmacologic Substance
| - 1496. 31
- [Mandibular right second molar ( HL7V3.0 )] (UMLS (HL7) C0227074) tooth 31 =Body Part, Organ, or Organ Component =Permanent dentition;
|
- 1447. 3-hydroxy-3-methylglutaryl-Coenzyme A Reductase
- [Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis. ( MSH )] (UMLS (NCI) C0063164) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 1497. 31-32 COMP WKS GESTATION
- [ ] (UMLS (ICD9CM) C1135245) 31-32 completed weeks of gestation;
=Temporal Concept |
- 1448. 3-Hydroxy-5-methoxy-6-methyl-2-pentyl-4H-pyran-4-one
- (UMLS (NCI) C0647702) =Organic Chemical; Pharmacologic Substance
| - 1498. 311C90
- (UMLS (NCI) C0289361) =Organic Chemical; Pharmacologic Substance ;
|
- 1449. 3-Hydroxy-alpha-methyl-L-tyrosine
- [A phenylalanine derivative and an aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the central nervous system. The antihypertensive action of methyldopa seems to be attributable to its conversion into alpha-methylnorepinephrine, which is a potent alpha-2 adrenergic agonist that binds to and stimulates potent central inhibitory alpha-2 adrenergic receptors. This results in a decrease in sympathetic outflow and decreased blood pressure. ( NCI )] (UMLS (NCI) C0025741) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine =dihydroxyphenylalanine;
[CV490] ANTIHYPERTENSIVES, OTHER =(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic Acid;
METHYLDOPATE;
METHYLDOPA 250 MG;
METHYLDOPA 125 MG;
METHYLDOPA 500 MG | - 1499. 31a
- [Mandibular right second molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553671) =Medical Device =Artificial dentition;
|
- 1450. 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one
- [A naturally occurring steroid with estrogenic activity obtained from the urine of pregnant mares. ( NCI )] (UMLS (NCI) C0014654) =Steroid; Pharmacologic Substance; Hormone
| - 1500. 31ad
- [Mandibular right second molar abutment distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1553673) =Medical Device =Artificial dentition;
|
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