3-Ethyl-3-methylpyrrolidine-2,5-dione
[A succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures. ( NCI )]
UMLS (NCI) C0015043- Organic Chemical
- Pharmacologic Substance
Relation/PAR: [CN400] ANTICONVULSANTS
succinimide
succinimide
Relation/CHD: ETHOSUXIMIDE 250 MG
ETHOSUXIMIDE 250 MG/5ML
ETHOSUXIMIDE 250 MG/5ML
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