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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
E E0 E6 E7 EA EB EC ED EE EF EG EH EI EJ EK EL EM EN EO EP EQ ER ES ET EU EV EW EX EY
ET ETA ETC ETE ETH ETI ETO ETR ETS

3-Ethyl-3-methylpyrrolidine-2,5-dione

[A succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures. ( NCI )]
UMLS (NCI) C0015043
 
Organic Chemical
Pharmacologic Substance
Relation/PAR: [CN400] ANTICONVULSANTS
succinimide
Relation/CHD: ETHOSUXIMIDE 250 MG
ETHOSUXIMIDE 250 MG/5ML
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