[A disintegrin and metalloproteinase with thrombospondin motifs-9 (ADAMTS9), encoded by the ADAMTS9 gene, is a member of the ADAMTS protein family. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This enzyme contains four C-terminal TS motifs. The spacer domain and the TSP Type-1 domains are important for a tight interaction with the extracellular matrix. The precursor is cleaved by a furin endopeptidase. Two isoforms, a long form and a short form, may be produced by alternative splicing. ADAMTS9 is secreted and associated with the extracellular matrix. It is highly expressed in all fetal tissues and expressed slightly in adult ovary, pancreas, heart, kidney, lung, placenta, spinal cord and brain. (From LocusLink, Swiss_Prot and NCI) ( NCI )]
UMLS (NCI) C1257533A Disintegrin and Metalloproteinase with Thrombospondin Motifs-9
ADAMTS9
ADAM-TS9
- Amino Acid, Peptide, or Protein
- Enzyme