4B5 monoclonal antibody anti-idiotype vaccine
[A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id 4B5 IgG was capable of eliciting both cellular and humoral immune responses against GD2 expression tumor cells. ( NCI )]
UMLS (NCI) C0879386MoAb 4B5 anti-idiotype vaccine
Monoclonal Antibody 4B5 Anti-Idiotype Vaccine
Monoclonal Antibody 4B5 Anti-Idiotype Vaccine
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor
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