[The sodium salt form of benzylpenicillin, a semi-synthetic, broad-spectrum penicillin antibiotic with bactericidal activity. Benzylpenicillin sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. ( NCI )]
UMLS (NCI) C0037540 - Organic Chemical
- Antibiotic
Relation/PAR: Penicillin G Benzathine
PENICILLIN G PROCAINE
PENICILLIN
Relation/CHD: PENICILLIN G SODIUM 5000000 UNT