- 1. 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1h-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-2-propenamide
- [A pyrrolo(1,4)benzodiazepine antineoplastic antibiotic isolated from the bacterium Streptomyces refuineus var. thermotolerans. Anthramycin binds covalently to guanine in the minor groove of DNA, thereby inhibiting DNA replication and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0003167) =Organic Chemical; Antibiotic
| - 51. Atherosclerosis excluding heart/brain
- (UMLS (ICPC) C0497251) (Atherosclerosis excluding heart/brain; ATEROSKLEROSISA (ESKL.BIHOTZA/BURMINA); Aterosklerose ex hjerte/hjerne; Atherosclerose ex coron/cerebr; ATEROSKLEROOSI/VERISUONTEN KALKKEUTUMINEN (PL SYDAN/AIVOT); Atherosclerose SF coeur/cerveau; Atherosklerose ex coron/cerebral; (108); atherosclerosis (kiv. sziv, agy); Aterosclerosi escl cuore/cervello; ATHEROSKLEROSE EKS HJERTE/HJERNE; Aterosclerose excl coracao/cerebro; Ateroesclerosis ex card/cereb; ARTERIOSKLEROS EXKL HJARTA/HJARNA) Atherosclerosis excl heart/brain; =Disease or Syndrome =CIRCULATORY; Diagnosis/Diseases Component
|
- 2. A therapeutic substitution was dispensed.
- (UMLS (HL7) C1549559) =Idea or Concept =Substitution Status;
| - 52. ATHEROSCLEROSIS NEC
- (UMLS (ICD9CM) C0004155) =Disease or Syndrome
|
- 3. AT
- [A country in Central Europe, north of Italy and Slovenia. (NCI) ( NCI )] (UMLS (NCI) C0004348) =Geographic Area ;
| - 53. ATHEROSCLEROSIS NOS
- (UMLS (ICD9CM) C0017327) =Disease or Syndrome
|
- 4. At a designated date/time
- (UMLS (HL7) C1548179) =Temporal Concept =Invocation event;
| - 54. Atherosclerosis of bypass graft of the extremities, unspecified graft
- [ ] (UMLS (ICD9CM) C0375301) =Disease or Syndrome
|
- 5. AT Hook Domain
- [Highly conserved peptide motifs of the HMG-I(Y) proteins that preferentially bind, in vivo and in vitro, to the narrow minor groove of stretches of AT-rich DNA. The AT Hook Motif tethers and unbends the minor groove of the DNA with very little specificity for the DNA sequence. The AT hook motif has a narrow DNA recognize surface which is devoid of hydrophobic amino acids and does not significantly distort the B-form DNA structure. ( NCI )] (UMLS (NCI) C0949662) AT Hook Motif;
ATH; =Amino Acid Sequence | - 55. Atherosclerosis of native arteries of the extremities
- [ ] (UMLS (ICD9CM) C0155735) =Disease or Syndrome ;
|
- 6. AT Mutated
- [Ataxia Telangiectasia Mutated Protein, encoded by the ATM gene, belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates and functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, which results in a defect in cell cycle regulation and DNA repair. Mutations are also associated with sensitivity to DNA damaging agents such as ionizing radiation. At least 3 alternatively spliced transcript variants encoding distinct isoforms, have been identified. (from LocusLink) ( NCI )] (UMLS (NCI) C0298973) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 56. Atherosclerosis of native arteries of the extremities, unspecified
- [ ] (UMLS (ICD9CM) C0375294) =Disease or Syndrome
|
- 7. At Rest
- (UMLS (NCI) C0443144) =Functional Concept
| - 57. Atherosclerosis of other native arteries of the extremities
- [ ] (UMLS (ICD9CM) C0375299) =Disease or Syndrome
|
- 8. AT Rich Interactive Domain 1B Protein
- [Widely expressed by human PLU-1 Gene (RBBP Family) at varying levels (highest in Sertoli cells), 1544-aa 176-kDa nuclear RBP2-Like Protein contains 3 Cys-rich zinc-binding DNA-binding PHD/LAP domains, a DNA-binding dead ringer domain, 5 putative nuclear localization signals, a putative DNA/chromatin binding motif, and other conserved regions of unknown function. With an additional 137 amino acids, 1681-aa 190-kDa RBBP2H1A appears to be an alternate PLU-1 product that shares 56% overall amino acid sequence identity with RBBP2, important in RB tumor suppressor regulation. (NCI) ( NCI )] (UMLS (NCI) C1321892) JARID1B;
Jumonji Protein; PLU-1; PLU-1 Protein; PUT1; RBBP2H1A; RBP2-Like Protein; Retinoblastoma-Binding Protein 2 Homolog 1A; =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 58. Atherosclerosis of renal artery
- [ ] (UMLS (ICD9CM) C0155734) =Disease or Syndrome ;
|
- 9. At time service is completed
- (UMLS (HL7) C1548177) =Temporal Concept =Invocation event;
| - 59. ATHETOID CEREBRAL PALSY
- [ ] (UMLS (ICD9CM) C0270742) =Disease or Syndrome
|
- 10. At time service is started
- (UMLS (HL7) C1548178) =Temporal Concept =Invocation event;
| - 60. athetosis
- [A dyskinesia characterized by an inability to maintain the fingers, toes, tongue, or other body parts in a stable position, resulting in continuous slow, sinusoidal, and flowing involuntary movements. This condition is frequently accompanied by CHOREA, where it is referred to as choreoathetosis. Athetosis may occur as a manifestation of BASAL GANGLIA DISEASES or DRUG TOXICITY. (From Adams et al., Principles of Neurology, 6th ed, p76) ( MSH )] (UMLS (CSP) C0004158) =Sign or Symptom
|
- 11. AT-125
- (UMLS (NCI) C0104485) =Organic Chemical; Pharmacologic Substance ;
| - 61. Athletic Trainer
- (UMLS (HL7) C1552343) =Intellectual Product =Specialist/Technologist;
|
- 12. AT-Hook Protein
- [Members of this family of high mobility group (HMG) proteins participate in a wide variety of nuclear processes ranging from chromosome and chromatin mechanics to acting as architectural transcription factors that regulate the expression of numerous genes. As a consequence, they function in the cell as highly connected nodes of protein-DNA and protein-protein interactions that influence a diverse array of normal biological processes including growth, proliferation, differentiation and death. Each protein contains three copies of the AT-hook, that preferentially binds to the minor groove of stretches of AT-rich sequence. HMGA genes are bona fide proto-oncogenes that promote tumor progression and metastasis when overexpressed. High constitutive HMGA protein levels are among the most consistent feature observed in all types of cancers with increasing concentrations being correlated with increasing malignancy. (Review in Gene 2001 277:63-81) ( NCI )] (UMLS (NCI) C0905617) HMGA Family Protein;
HMGI(Y) Protein; HMG-I(Y) Protein; HMG-I/Y Protein; HMG-I/Y/C; =Amino Acid, Peptide, or Protein; Biologically Active Substance ; | - 62. Athrombin-K
- (UMLS (NCI) C0917972) =Organic Chemical; Pharmacologic Substance ;
|
- 13. At-Risk Population
- [Population groups with an increased likelihood of a disease or other health issue, eg smoking, drug use, teen pregnancy. ( NCI )] (UMLS (NCI) C0242444) =Population Group ;
| - 63. athymia
- [ ] (UMLS (CSP) C0599540) =Disease or Syndrome ;
|
- 14. AT/RT
- [An aggressive malignant embryonal neoplasm arising from the central nervous system. It is composed of cells with a large eccentric nucleus, prominent nucleolus, and abundant cytoplasm. It may be associated with loss of chromosome 22. The vast majority of cases occur in childhood. Symptoms include lethargy, vomiting, cranial nerve palsy, headache, and hemiplegia. ( NCI )] (UMLS (NCI) C1266184) Atypical Teratoid/Rhabdoid Tumor;
Central Nervous System Rhabdoid Neoplasm; Central Nervous System Rhabdoid Tumor; CNS Rhabdoid Neoplasm; CNS Rhabdoid Tumor; Malignant Brain Rhabdoid Neoplasm; Malignant Brain Rhabdoid Tumor; Malignant Rhabdoid Neoplasm of Brain; Malignant Rhabdoid Neoplasm of the Brain; Malignant Rhabdoid Tumor of Brain; Malignant Rhabdoid Tumor of the Brain; Primary Malignant Brain Rhabdoid Neoplasm; Primary Malignant Brain Rhabdoid Tumor; Primary Malignant Rhabdoid Neoplasm of Brain; Primary Malignant Rhabdoid Neoplasm of the Brain; Primary Malignant Rhabdoid Tumor of Brain; Primary Malignant Rhabdoid Tumor of the Brain; Rhabdoid Neoplasm of Central Nervous System; Rhabdoid Neoplasm of CNS; Rhabdoid Neoplasm of the Central Nervous System; Rhabdoid Neoplasm of the CNS; Rhabdoid Tumor of Central Nervous System; Rhabdoid Tumor of CNS; Rhabdoid Tumor of the Central Nervous System; Rhabdoid Tumor of the CNS =Neoplastic Process | - 64. athymic mouse
- [mutant mouse homozygous for the recessive gene, nude, which fail to develop a thymus. ( CSP )] (UMLS (CSP) C0025932) =Mammal ;
=laboratory mouse; |
- 15. Atamestane
- [A drug being studied in the treatment of cancer. It belongs to the family of drugs called antiestrogens. Atamestane blocks the production of the hormone estrogen in the body. ( NCI )] (UMLS (NCI) C0074442) =Steroid; Pharmacologic Substance ;
| - 65. ATIC-ALK Fusion Protein Expression
- (UMLS (NCI) C1510696) =Cell or Molecular Dysfunction ;
|
- 16. Atamestane/Toremifene
- (UMLS (NCI) C0935775) =Therapeutic or Preventive Procedure ;
| - 66. Atiprimod
- [An orally bioavailable small molecule belonging to the azaspirane class of cationic amphiphilic agents with anti-inflammatory, antineoplastic, and antiangiogenic properties. Atiprimod inhibits the phosphorylation of signal transducer and activator of transcription 3 (STAT3), blocking the signalling pathways of interleukin-6 and vascular endothelial growth factor (VEGF) and downregulating the anti-apoptotic proteins Bcl-2, Bcl-XL, and Mcl-1, thereby inhibiting cell proliferation, inducing cell cycle arrest, and inducing apoptosis. ( NCI )] (UMLS (NCI) C0754307) N,N-Diethyl-8,8-dipropyl-2-azaspiro(4.5)decane-2-propanamine;
=Organic Chemical; Pharmacologic Substance |
- 17. Atarax
- (UMLS (NCI) C0684229) =Organic Chemical; Pharmacologic Substance
| - 67. Ativan
- (UMLS (NCI) C0699194) =Organic Chemical; Pharmacologic Substance ;
|
- 18. ataxia
- [awkwardness in motor behavior associated with loss of afferent information from the moving part or with loss of control mechanism of the cerebellum. ( CSP )] (UMLS (CSP) C0004134) =Sign or Symptom
| - 68. Atlanto-Axial Joint
- [The joint involving the atlas and axis bones. ( MSH )] (UMLS (NCI) C0004168) =Body Space or Junction
|
- 19. ATAXIA
- (UMLS (ICD9CM) C1135207) Ataxia as late effect of cerebrovascular disease =Disease or Syndrome
| - 69. Atlanto-Occipital Joint
- (UMLS (NCI) C0004169) =Body Space or Junction
|
- 20. ataxia telangiectasia
- [inherited disease characterized by onset in early childhood of progressive cerebellar ataxia, oculocutaneous telangiectasis, and severe sinopulmonary infections. ( CSP )] (UMLS (CSP) C0004135) =Disease or Syndrome
| - 70. atlas
- [Works consisting of collections of illustrative plates, charts, etc., usually with explanatory captions. ( MSH )] (UMLS (CSP) C0004171) =Manufactured Object; Intellectual Product ;
|
- 21. Ataxia Telangiectasia and Rad3 Related Protein
- [Ataxia Telangiectasia and Rad3 Related Protein (ATR), encoded by the ATR gene, is a member of the PIK (phosphatidylinositol kinase)-related kinase family that are high molecular weight kinases involved in cell cycle progression, DNA recombination, and the detection of DNA damage. ATR is essential for the viability of human somatic cells. ATR and ATRIP (ATR-interacting protein) are mutually dependent partners in cell cycle checkpoint signaling pathways - ATR phosphorylates ATRIP that regulates ATR expression and is an essential component of the DNA damage checkpoint pathway. ATR phosphorylates checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. ATR may be particularly essential in the early embryo to sense incomplete DNA replication and prevent mitotic catastrophe. (From OMIM, LocusLink and NCI) ( NCI )] (UMLS (NCI) C0912983) ATR;
FRAP-Related Protein-1; FRP1; Protein Kinase ATR; Rad3 Related Protein; =Amino Acid, Peptide, or Protein; Enzyme | - 71. Atlas of the Vertebra
- (UMLS (NCI) C0004170) =Body Part, Organ, or Organ Component
|
- 22. Ataxia Telangiectasia Mutated (Includes Complementation Groups A, C and D) Gene
- [This gene is involved in apoptosis, DNA repair and cell cycle regulation. ( NCI )] (UMLS (NCI) C0919524) ATM;
ATM Gene; =Gene or Genome ; | - 72. ATLAS-AXIS FUSION
- [ ] (UMLS (ICD9CM) C0186005) =Therapeutic or Preventive Procedure
|
- 23. Ataxia-Telangiectasia and Rad3-Related Gene
- [This gene is involved in cell cycle checkpoints and DNA recombination. ( NCI )] (UMLS (NCI) C1332120) ATR;
ATR Gene =Gene or Genome ; | - 73. atm
- [Non-SI unit of pressure equal to 101 325 Pa. ( NCI )] (UMLS (NCI) C0678214) =Quantitative Concept ;
=UnitOfMeasureAtomInsens; UnitOfMeasureAtomSens |
- 24. Ataxia-Telangiectasia Variant 1
- [A disorder, wherein unstable chromosomes have a tendency to break and become rearranged, characterized by microcephaly, stunted growth, subnormal mental development, cafe-au-lait spots, and immunodeficiency. The syndrome is named after the University of Nijmegen in the Netherlands. (JABL99) ( NCI )] (UMLS (CSP) C0398791) =Congenital Abnormality; Disease or Syndrome =ataxia telangiectasia;
| - 74. ATM Gene Mutation
- (UMLS (NCI) C1510697) =Cell or Molecular Dysfunction ;
|
- 25. ataxic gait
- [(ah-TAK-sik) Awkward, uncoordinated walking. ( NCI )] (UMLS (NCI) C0751837) Gait Ataxia =Sign or Symptom =Cerebellar Ataxia;
Gait Disorders, Neurologic | - 75. ATM Signaling Pathway
- [The ataxia telangiectasia-mutated gene (ATM) encodes a protein kinase that acts as a tumor suppressor. ATM activation by ionizing radiation damage to DNA stimulates DNA repair and blocks progression through the cell cycle. Mutation of the ATM gene causes the disease ataxia telangiectasia which involves an inherited predisposition to some cancers. To play this role ATM interacts with a broad network of proteins, including checkpoint factors (chk1, chk2), tumor suppressors (p53 and BRCA), DNA repair factors (RAD50, RAD51, GADD45), and other signaling molecules (c-Abl and NF-kB). In addition to regulating DNA repair and the cell cycle, ATM can also trigger apoptosis in radiation treated cells. (Biocarta) ( NCI )] (UMLS (NCI) C1510698) =Molecular Function ;
|
- 26. atelectasis
- [collapse of all or part of a lung due to bronchial plugging or the chest cavity being opened to atomspheric pressure. ( CSP )] (UMLS (CSP) C0004144) =Pathologic Function
| - 76. ATMOS PRESS/COMPOS CONTR
- [ ] (UMLS (ICD9CM) C0178051) =Therapeutic or Preventive Procedure
|
- 27. Ateles
- [ ] (UMLS (CSP) C0004146) =Mammal
| - 77. atmosphere
- [The gaseous envelope surrounding a planet or similar body. (From Random House Unabridged Dictionary, 2d ed) ( MSH )] (UMLS (CSP) C0004178) =Natural Phenomenon or Process ;
|
- 28. Ateline herpesvirus group
- [ ] (UMLS (CSP) C0598476) =Virus ;
| - 78. atmosphere (technical)
- [1 kgf/cm2 ( HL7V3.0 )] (UMLS (HL7) C1553014) =Quantitative Concept =UnitOfMeasureAtomInsens;
UnitOfMeasureAtomSens |
- 29. atenolol
- [l-p-carbamoylmethylphenoxy-3-isopropylamino -2-propanol, is a peripheral beta blocker used as an antihypertensive; propranolol, by contrast, also has CNS effects. ( CSP )] (UMLS (CSP) C0004147) =Organic Chemical; Pharmacologic Substance ;
| - 79. atmosphere/weather
- [gaseous envelope surrounding a planet or similar body including weather which is the state of the atmosphere at a given time and place, with respect to variables such as temperature, moisture, wind velocity, and barometric pressure. ( CSP )] (UMLS (CSP) C0935443) =Natural Phenomenon or Process ;
=environment; =climate |
- 30. Aterial puncture
- (UMLS (HL7) C1548740) =Diagnostic Procedure =Specimen Collection Method;
| - 80. atmospheric pressure
- [pressure at any point in an atmosphere due solely to the weight of the atmospheric gases above the point concerned. ( CSP )] (UMLS (CSP) C0004180) =Natural Phenomenon or Process ;
|
- 31. ATF 2
- [A basic leucine zipper transcription factor that is highly homologous to ACTIVATING TRANSCRIPTION FACTOR 2. It binds the consensus site TGACGTCA of the cyclic AMP response element in partnership with either PROTO-ONCOGENE PROTEINS C-JUN or activating transcription factor 2. ( MSH )] (UMLS (CSP) C0213709) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 81. atomic absorption spectrometry
- [spectrophotometric techniques in which the samples are examined in the form of atoms based on their unique energy levels for electrons; particularly used to analyze trace elements. ( CSP )] (UMLS (CSP) C0037806) =Laboratory Procedure ;
=spectrometry; ObservationMethod |
- 32. ATGAM
- (UMLS (NCI) C0004149) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 82. atomic energy
- [Energy released by nuclear fission or nuclear fusion. ( MSH )] (UMLS (CSP) C0028572) =Natural Phenomenon or Process ;
|
- 33. ATH EXT AUTOLOGS BPS GFT
- [ ] (UMLS (ICD9CM) C0375302) =Disease or Syndrome
| - 83. atomic orbital
- [ ] (UMLS (CSP) C0598889) =Qualitative Concept ;
|
- 34. ATH EXT NONAUTLG BPS GFT
- (UMLS (ICD9CM) C1112691) Atherosclerosis of nonautologous vein bypass graft of the extremities =Disease or Syndrome ;
| - 84. Atomic service/test/observation (test code or treatment code)
- (UMLS (HL7) C1549572) =Idea or Concept =Nature of Service/Test/Observation;
|
- 35. ATH EXT NTV ART GNGRENE
- [ ] (UMLS (ICD9CM) C0375298) =Disease or Syndrome
| - 85. Atonic Epilepsy
- (UMLS (NCI) C0086236) =Disease or Syndrome ;
|
- 36. ATH EXT NTV ART ULCRTION
- [ ] (UMLS (ICD9CM) C0375297) =Disease or Syndrome
| - 86. atonic seizure
- [ ] (UMLS (CSP) C0270846) =Disease or Syndrome
|
- 37. ATH EXT NTV AT W CLAUDCT
- [ ] (UMLS (ICD9CM) C0375295) =Disease or Syndrome
| - 87. ATONY OF BLADDER
- (UMLS (ICD9CM) C0403645) =Finding
|
- 38. ATH EXT NTV AT W RST PN
- [ ] (UMLS (ICD9CM) C0837139) Atherosclerosis of the extremities with rest pain =Disease or Syndrome
| - 88. Atopic Allergy
- [genetic predisposition toward the development of immediate (type I) hypersensitivity reactions against common environmental antigens (atopic allergy); the most common clinical manifestation is allergic rhinitis; bronchial asthmas, atopic dermatitis and food allergy also occur. ( CSP )] (UMLS (NCI) C0392707) =Pathologic Function =Allergy;
=ARNASESTUA; allergic dermatitis; Allergic rhinitis due to pollen |
- 39. Athapaskan
- (UMLS (HL7) C1697807) =Language =AthapaskanEyak;
=Apachean; PacificCoastAthapaskan; SouthernAlaska; CentralAlaskaYukon | - 89. Atopic dermatitis and related conditions
- (UMLS (ICD9CM) C0004187) =Disease or Syndrome ;
|
- 40. AthapaskanEyak
- (UMLS (HL7) C1698048) =Language ;
=Nadene; =Eyak; Athapaskan | - 90. Atopic dermatitis/eczema
- (UMLS (ICPC) C0497391) (Atopic dermatitis/eczema; DERMATITI ATOPIKOA; Atopisk dermatit/eksem; Constitutioneel eczeem; ATOOPPINEN IHOTTUMA/EKSEEMA; Dermatite atopique/eczema; Dermatitis atopica/chron Ekzem; atopik dermatitis/ekzema; atopias dermatitis/eccema; Dermatite atopica/eczema; EKSEM/ATOPISK DERMATITT; Dermatite/eczema atopico; Dermatitis atopica/eccema; ATOPISKT UTSLAG/EKSEM) =Disease or Syndrome ;
=Diagnosis/Diseases Component; Integument |
- 41. Atheism
- (UMLS (HL7) C0337687) =Idea or Concept ;
=Religious Affiliation; | - 91. Atorvastatin Calcium
- [The calcium salt form of atorvastatin, a synthetic lipid-lowering agent. Atorvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. Atorvastatin also increases the number of LDL receptors on hepatic cell surfaces to enhance uptake and catabolism of LDL and reduces LDL production and the number of LDL particles. This agent lowers plasma cholesterol and lipoprotein levels and modulates immune responses by suppressing MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. (NCI04) ( NCI )] (UMLS (NCI) C0286650) =Organic Chemical; Pharmacologic Substance =(betaR,deltaR)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid;
=atorvastatin 10 MG; atorvastatin 20 MG; ATORVASTATIN CALCIUM 80 MG; atorvastatin 40 MG; |
- 42. Atheist
- (UMLS (HL7) C0344345) =Population Group ;
=religion; | - 92. ATOVAQUONE
- [broad-spectrum antiparasitic drug found to be active against Pneumocystis carinii pneumonia in AIDS patients. ( CSP )] (UMLS (NCI) C0165603) =Organic Chemical; Pharmacologic Substance =[AM700] ANTIFUNGALS;
[AP000] ANTIPARASITICS; Antiprotozoal Agent; naphthoquinone; [AP109] ANTIPROTOZOALS, OTHER; =Atovaquone 150 MG/ML; ATOVAQUONE 250 MG; ATOVAQUONE 62.5 MG |
- 43. Atheroembolism
- [Blocking of a blood vessel by CHOLESTEROL-rich atheromatous deposits, generally occurring in the flow from a large artery to small arterial branches. It is also called arterial-arterial embolization or atheroembolism which may be spontaneous or iatrogenic. Patients with spontaneous atheroembolism often have painful, cyanotic digits of acute onset. ( MSH )] (UMLS (ICD9CM) C0149649) =Anatomical Abnormality =embolism;
=Blue Toe Syndrome | - 93. ATP
- [ATPase, Aminophospholipid Transporter-Like, Class I, Type 8A, Member 2, encoded by the ATP8A2 gene, is an integral membrane protein has similarity to P-type ATPases, proteins that drive uphill transport of ions across membranes. Transfection of antisense constructs into a nontumorigenic cell line rendered the cells tumorigenic in nude mice. (from Swiss-Prot and OMIM) ( NCI )] (UMLS (NCI) C1366832) ATP8A2;
ATPase, Aminophospholipid Transporter-Like, Class I, Type 8A, Member 2; ATPIB; DKFZP434B1913; IB; ML-1; ML-1 Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 44. Atheroembolism Of extremities
- [ ] (UMLS (ICD9CM) C1135211) =Disease or Syndrome
| - 94. ATP biosynthesis (oxidative)
- [electron transfer through the cytochrome system liberating free energy which is transformed into high-energy phosphate bonds. ( CSP )] (UMLS (CSP) C0030013) =Molecular Function ;
=aerobiosis; phosphorylation |
- 45. Atheroembolism of kidney
- [ ] (UMLS (ICD9CM) C1135215) ATHEROEMBOLISM, KIDNEY =Disease or Syndrome
| - 95. ATP citrate (pro3s) lyase
- [An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8. ( MSH )] (UMLS (CSP) C0004199) =Amino Acid, Peptide, or Protein; Enzyme
|
- 46. Atheroembolism of lower extremity
- [ ] (UMLS (ICD9CM) C1135213) ATHEROEMBOLISM,LOWER EXT =Disease or Syndrome
| - 96. ATP Hydrolysis
- [ATP Hydrolysis is the cleavage of a high-energy phosphate bond of adenosine triphosphate by the addition of water. The energy derived from hydrolysis of ATP is used to drive metabolic reactions including nucleic acid and protein synthesis, to move molecules against concentration gradients (active transport), and to produce mechanical motion (contraction of microfibrils and microtubules). ( NCI )] (UMLS (NCI) C1510699) =Molecular Function ;
|
- 47. Atheroembolism of other site
- [ ] (UMLS (ICD9CM) C1135216) Atheroembolism of other sites;
ATHEROEMBOLISM, SITE NEC =Disease or Syndrome | - 97. ATP phosphohydrolase (Na+ K+ transporting)
- [family of ouabain-sensitive, ATP-driven, transmembrane molecular pumps which maintain opposing concentration gradients of sodium and potassium across cell membranes term not valid for FY 92. ( CSP )] (UMLS (CSP) C0001479) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 48. Atheroembolism of upper extremity
- [ ] (UMLS (ICD9CM) C1135212) ATHEROEMBOLISM,UPPER EXT =Disease or Syndrome
| - 98. ATP receptor
- [ ] (UMLS (CSP) C0004204) =Amino Acid, Peptide, or Protein; Receptor
|
- 49. atheroma
- [yellowish plaques containing cholesterol, lipoid material, and lipophages formed within the intima and inner media of large and medium-sized arteries in atherosclerosis. ( CSP )] (UMLS (CSP) C0015697) =Acquired Abnormality =Atherosclerosis;
| - 99. ATP Synthesis
- (UMLS (NCI) C1510700) ATP Synthesis Pathway;
=Functional Concept ; |
- 50. atherosclerosis
- [age, lifestyle, diet, and gene related degeneration of arteries due to deposition of lipoid plaques (atheromas) on inner arterial walls; main cause of coronary artery disease, a leading cause of death. ( CSP )] (UMLS (CSP) C0004153) =Disease or Syndrome
| - 100. ATP-dependent DNA helicase II
- [Encoded by Ku Subunit Genes, tightly-associated 70-kDa Ku70 Protein and 80-kDa Ku80 Protein are subunits of heterodimeric DNA-binding Ku Protein, a DNA damage repair complex that, with the 470-kDa catalytic DNA-PKcs subunit forms DNA-dependent protein kinase, binds and repairs double-stranded DNA breaks, facilitates repair by nonhomologous end-joining, and is involved in V(D)J recombination. Ku also binds to DNA ends with a telomere binding protein and mediates telomere capping to prevent fusion of chromosome ends and genetic instability. KU70 and KU80 form a dyad-symmetrical ring molecule that encircles duplex DNA. Ku is identical to DNA helicase II, an ATP-dependent DNA unwinding enzyme. (NCI) ( NCI )] (UMLS (NCI) C1337080) Ku Protein =Amino Acid, Peptide, or Protein; Enzyme ;
|