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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
AT AT- ATA ATE ATF ATG ATH ATI ATL ATM ATO ATP ATQ ATR ATS ATT ATV ATY

AT Hook Domain

[Highly conserved peptide motifs of the HMG-I(Y) proteins that preferentially bind, in vivo and in vitro, to the narrow minor groove of stretches of AT-rich DNA. The AT Hook Motif tethers and unbends the minor groove of the DNA with very little specificity for the DNA sequence. The AT hook motif has a narrow DNA recognize surface which is devoid of hydrophobic amino acids and does not significantly distort the B-form DNA structure. ( NCI )]
UMLS (NCI) C0949662
AT Hook Motif
ATH
 
Amino Acid Sequence
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