- 1. 1,2,3,4,4a,4b,7,9,10,10a-Decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthrenepropionic Acid Delta-Lactone
- [A progesterone derivative with antineoplastic activity. Testolactone inhibits steroid aromatase, thereby preventing the formation of estrogen from adrenal androstenedione and reducing endogenous estrogen levels. (NCI04) ( NCI )] (UMLS (NCI) C0039600) =Steroid; Pharmacologic Substance; Hormone =Androstadienes;
Homosteroids; [AN500] ANTINEOPLASTIC HORMONES; =TESTOLACTONE 50 MG | - 51. ABC-DLBCL
- [A biologic subset of diffuse large B-cell lymphomas with a unique molecular signature or expression profile. It represents approximately 30% of diffuse large B-cell lymphomas, and is characterized by the expression of CD44, PKCbeta1, Cyclin D2, BCL-2, and IRF4/MUM1 genes. Morphologically, these lymphomas are either centroblastic or immunoblastic (ratio 2:1). Patients with this type of diffuse large B-cell lymphoma are reported to have a less favorable outcome compared to those with a germinal center B-cell expression profile, with a 5-year survival rate of 35% and a median survival of 2 years. — 2004 ( NCI )] (UMLS (NCI) C1333296) Activated B-Cell-Like Diffuse Large B-Cell Lymphoma;
Diffuse Large B-Cell Lymphoma with an Activated B-Cell Expression Profile; =Neoplastic Process ; |
- 2. 1-ABaP
- [A polycyclic aromatic hydrocarbon belongs to the family of mutagen benzo(a)pyrene. 1-aminobenzo(a)pyrene consists of five fused rings with an amino-group attached to the first carbon atom of the aromatic hydrocarbon ring with potential carcinogenicity. ( NCI )] (UMLS (NCI) C0768966) 1-Aminobenzo[a]pyrene;
=Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance | - 52. ABCB1
- [gene product of the multidrug resistance gene mdr-1, believed to be a membrane spanning transporter that can pump a wide variety of cytotoxic agents out of the cell. ( CSP )] (UMLS (NCI) C0242643) =Amino Acid, Peptide, or Protein; Biologically Active Substance =membrane transport protein;
|
- 3. 3-ABaP
- [A polycyclic aromatic hydrocarbon belongs to the family of mutagen benzo(a)pyrene. 3-aminobenzo(a)pyrene consists of five fused rings with an amino-group attached to the third carbon atom of the aromatic hydrocarbon ring with potential carcinogenicity. ( NCI )] (UMLS (NCI) C0768968) 3-Aminobenzo[a]pyrene;
=Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance | - 53. ABCB1
- [This gene plays a role in multi-drug resistance and is involved in blood-brain barrier transport. ( NCI )] (UMLS (NCI) C0376622) =Gene or Genome
|
- 4. Ab
- [infection-fighting protein molecule in blood or secretory fluids that tags, neutralizes, and helps destroy pathogenic microorganisms such as bacteria or viruses and toxins; they are generally known as immunoglobulins, and are made and secreted by B-lymphocytes in response to stimulation by antigens; each specific antibody binds only to the specific antigen that stimulated its production. ( CSP )] (UMLS (NCI) C0003241) =Amino Acid, Peptide, or Protein; Immunologic Factor
| - 54. ABCB6
- [This gene is involved in multi-drug resistance, antigen presentation and is postulated to play a role in mitochondrial function. ( NCI )] (UMLS (NCI) C1332001) ABCB6 Gene;
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 Gene; =Gene or Genome ; |
- 5. AB FINDINGS-BREAST NEC
- [ ] (UMLS (ICD9CM) C0949148) Other abnormal findings on radiological examination of breast =Disease or Syndrome
| - 55. ABCB6
- [ATP-Binding Cassette, Sub-Family B, Member 6, encoded by the ABCB6 gene, is a membrane-associated protein of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. It could be involved in the transport of heme from the mitochondria to the cytosol. This gene is a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. (From LocusLink, Swiss_Prot and NCI) ( NCI )] (UMLS (NCI) C1334777) ATP-Binding Cassette, Sub-Family B, Member 6;
Mitochondrial ABC Protein 3 =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 6. AB FTL HRT RT/RH B/F LAB
- [ ] (UMLS (ICD9CM) C0695249) =Pathologic Function
| - 56. ABCC1
- [The MRP1 Protein constitutes a multidrug resistance-associated plasma membrane drug-efflux pump, detectable in lung, testis, and peripheral blood mononuclear cells. This transporter protein is similar to ABC superfamily of transport systems and is over expressed in a multidrug-resistant SCLC cell line. (from OMIM 158343 and NCI) ( NCI )] (UMLS (NCI) C0906368) ATP-Binding Cassette, Sub-Family C, Member 1;
MRP1 Protein; Multiple Drug Resistance-Associated Protein; =Amino Acid, Peptide, or Protein; Biologically Active Substance ; ◊ [This gene plays a role in multi-drug resistance and organic anion transport. ( NCI )] (UMLS (NCI) C0919458) ABCC1 Gene; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 Gene; Gene or Genome ; |
- 7. AB FTL HRT RT/RH DUR LAB
- [ ] (UMLS (ICD9CM) C0695250) =Pathologic Function
| - 57. ABCcodes
- [Five character alphabetic codes fit into current claims processing software or onto standard paper claim forms. ABC Codes give business parity to licensed CAM and nurse providers who file claims to insurance companies. . ( HL7V3.0 )] (UMLS (HL7) C1553861) =Intellectual Product =CodeSystem;
|
- 8. AB FTL HRT RT/RHY NOS
- [ ] (UMLS (ICD9CM) C0695251) =Pathologic Function
| - 58. Abcess
- (UMLS (HL7) C1550609) =Body Substance =SpecimenEntityType;
|
- 9. AB MAMMOGRAM NOS
- [ ] (UMLS (ICD9CM) C0949146) Abnormal mammogram, unspecified =Disease or Syndrome
| - 59. ABCG2
- [Human ATP binding cassette transporter-G2 protein (2436 aa, ~270 kDa) is encoded by the human ABCG2 gene. This integral membrane protein plays a role in transport and is associated with drug resistance in tumor cell lines. ( NCI )] (UMLS (NCI) C0761993) ATP Binding Cassette Transporter G2;
ATP-Binding Cassette, Sub-Family G, Member 2; BCRP1 Protein; Breast Cancer Resistance Protein 1; Mitoxantrone Resistance Protein; Placenta Specific MDR Protein; Placenta-Specific ATP-Binding Cassette Transporter =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 10. AB NOS UNCOMPLICAT-COMP
- [ ] (UMLS (ICD9CM) C0156582) =Injury or Poisoning
| - 60. ABCG2
- [This gene plays a role in xenobiotic transport and multi-drug resistance. ( NCI )] (UMLS (NCI) C1332002) ABCG2 Gene;
ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 Gene; =Gene or Genome ; |
- 11. AB NOS UNCOMPLICAT-INC
- [ ] (UMLS (ICD9CM) C0156581) =Injury or Poisoning
| - 61. ABCM
- (UMLS (NCI) C0279181) =Therapeutic or Preventive Procedure
|
- 12. AB NOS UNCOMPLICAT-UNSP
- [ ] (UMLS (ICD9CM) C0156580) =Pathologic Function
| - 62. ABCX
- (UMLS (NCI) C0279465) =Therapeutic or Preventive Procedure
|
- 13. AB NOS W COMPL NEC-COMP
- [ ] (UMLS (ICD9CM) C0156575) =Pathologic Function
| - 63. ABD AORTIC EMBOLISM
- (UMLS (ICD9CM) C0013923) =Pathologic Function
|
- 14. AB NOS W COMPL NEC-INC
- [ ] (UMLS (ICD9CM) C0156574) =Pathologic Function
| - 64. ABD ARTERY RESEC W REPLA
- [ ] (UMLS (ICD9CM) C0190653) =Therapeutic or Preventive Procedure
|
- 15. AB NOS W COMPL NEC-UNSP
- [ ] (UMLS (ICD9CM) C0156573) =Injury or Poisoning
| - 65. ABD CONTR PHLEBOGRAM NEC
- [ ] (UMLS (ICD9CM) C0177794) =Diagnostic Procedure
|
- 16. AB NOS W COMPL NOS-COMP
- [ ] (UMLS (ICD9CM) C0156579) =Pathologic Function
| - 66. ABD HRN REP-GRF/PROS NEC
- [ ] (UMLS (ICD9CM) C0176962) =Therapeutic or Preventive Procedure
|
- 17. AB NOS W COMPL NOS-INC
- [ ] (UMLS (ICD9CM) C0156578) =Pathologic Function
| - 67. ABD PREG W INTRAUT PREG
- [ ] (UMLS (ICD9CM) C1135232) Abdominal pregnancy with intrauterine pregnancy;
=Disease or Syndrome |
- 18. AB NOS W COMPL NOS-UNSP
- (UMLS (ICD9CM) C1299558) Unspecified abortion with unspecified complication;
Unspecified type of abortion, unspecified, with unspecified complication =Pathologic Function | - 68. ABD PREG W/O INTRAU PREG
- [ ] (UMLS (ICD9CM) C1135231) Abdominal pregnancy without intrauterine pregnancy;
=Disease or Syndrome |
- 19. AB NOS W EMBOLISM-COMP
- [ ] (UMLS (ICD9CM) C0156571) =Injury or Poisoning
| - 69. ABD REGION DX PROC NEC
- [ ] (UMLS (ICD9CM) C0176972) =Diagnostic Procedure
|
- 20. AB NOS W EMBOLISM-INC
- [ ] (UMLS (ICD9CM) C0156570) =Disease or Syndrome
| - 70. ABD REPAIR-DIAPHR HERNIA
- (UMLS (ICD9CM) C0198463) =Therapeutic or Preventive Procedure
|
- 21. AB NOS W EMBOLISM-UNSP
- [ ] (UMLS (ICD9CM) C0156568) =Disease or Syndrome
| - 71. ABD VARICOS V LIGA-STRIP
- [ ] (UMLS (ICD9CM) C0176651) =Therapeutic or Preventive Procedure
|
- 22. AB NOS W METAB DIS-COMP
- [ ] (UMLS (ICD9CM) C0156563) =Injury or Poisoning
| - 72. ABD VEIN RESECT & ANAST
- (UMLS (ICD9CM) C0191072) =Therapeutic or Preventive Procedure
|
- 23. AB NOS W METAB DIS-INC
- [ ] (UMLS (ICD9CM) C0156562) =Injury or Poisoning
| - 73. ABD VEIN RESECT W REPLAC
- [ ] (UMLS (ICD9CM) C0176643) =Therapeutic or Preventive Procedure
|
- 24. AB NOS W METAB DIS-UNSP
- [ ] (UMLS (ICD9CM) C0156561) =Injury or Poisoning
| - 74. ABD VESSEL RESECT/ANAST
- [ ] (UMLS (ICD9CM) C0190618) =Therapeutic or Preventive Procedure
|
- 25. AB NOS W PELV DAMAG-COMP
- [ ] (UMLS (ICD9CM) C0156555) =Injury or Poisoning
| - 75. ABD WALL HERN REPAIR NEC
- [ ] (UMLS (ICD9CM) C0176961) =Therapeutic or Preventive Procedure
|
- 26. AB NOS W PELV DAMAG-INC
- [ ] (UMLS (ICD9CM) C0156554) =Injury or Poisoning
| - 76. ABD WALL SUTURE NEC
- [ ] (UMLS (ICD9CM) C0176977) =Therapeutic or Preventive Procedure
|
- 27. AB NOS W PELV DAMAG-UNSP
- [ ] (UMLS (ICD9CM) C1263817) Unspecified abortion complicated by damage to pelvic organs or tissues;
Unspecified type of abortion, unspecified, complicated by damage to pelvic organs or tissues; =Injury or Poisoning | - 77. ABD-B
- [Encoded by human HOXA9 Gene (ABD-B Family), 272-amino acid 30-kD Homeobox Protein A9 isoforms are class I sequence-specific DNA-binding homeobox transcription factors potentially involved in morphogenesis and myeloid differentiation; expression is spatially and temporally regulated during embryonic development. Frameshifted isoform B contains a distinct C-terminus lacking the homeodomain. HOXA9 acts within a developmental regulatory system that provides specific anterior-posterior positional identity to cells. Associated with acute myeloid leukemogenesis, a chimerically fused in-frame nucleoporin NUP98 amino terminal half to HOXA9 may inhibit differentiation or disrupt nucleocytoplasmic transport. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0386322) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 28. AB NOS W RENAL FAIL-COMP
- [ ] (UMLS (ICD9CM) C0156559) =Injury or Poisoning
| - 78. ABD-CORON ARTERY BYPASS
- [ ] (UMLS (ICD9CM) C0375941) =Therapeutic or Preventive Procedure
|
- 29. AB NOS W RENAL FAIL-INC
- [ ] (UMLS (ICD9CM) C0156558) =Injury or Poisoning
| - 79. ABDMNAL MASS EPIGASTRIC
- [ ] (UMLS (ICD9CM) C0375562) =Sign or Symptom
|
- 30. AB NOS W RENAL FAIL-UNSP
- [ ] (UMLS (ICD9CM) C0156556) =Disease or Syndrome
| - 80. ABDMNAL MASS GENERALIZED
- [ ] (UMLS (ICD9CM) C0375563) =Sign or Symptom
|
- 31. AB-DIC
- (UMLS (NCI) C0081426) =Therapeutic or Preventive Procedure ;
| - 81. ABDMNAL MASS LFT UP QUAD
- [ ] (UMLS (ICD9CM) C0375558) =Sign or Symptom
|
- 32. Abacavir
- [A synthetic carbocyclic nucleoside analog. In vivo, the activated triphosphate metabolite of abacavir is incorporated into the viral DNA instead of the natural substrate deoxyguanosine, thereby inhibiting human immunodeficiency virus (HIV) reverse transcriptase (RT) and, so, the replication of the viral DNA and infectious viral particles. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS. ( NCI )] (UMLS (NCI) C0663655) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM800] ANTIVIRALS; deoxyribonucleoside; Reverse Transcriptase Inhibitor; 1592U89 =Abacavir Sulfate; | - 82. ABDMNAL MASS LT LWR QUAD
- [ ] (UMLS (ICD9CM) C0375560) =Sign or Symptom
|
- 33. Abacavir Sulfate
- [The sulfate salt form of abacavir, a synthetic carbocyclic nucleoside analog. In vivo, the activated triphosphate metabolite of abacavir is incorporated into the viral DNA instead of the natural substrate deoxyguanosine, thereby inhibiting human immunodeficiency virus (HIV) reverse transcriptase (RT) and, so, the replication of the viral DNA and infectious viral particles. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS. ( NCI )] (UMLS (NCI) C0724515) ABACAVIR SULFATE PREPARATION;
=Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ; =Abacavir; =ABACAVIR SULFATE 100 MG/5ML; ABACAVIR SULFATE 300 MG; | - 83. ABDMNAL MASS OTH SPCF ST
- [ ] (UMLS (ICD9CM) C0375564) =Sign or Symptom
|
- 34. Abagovomab
- [A murine immunoglobulin G1 (IgG1) monoclonal anti-idiotype antibody (ACA125). Vaccination with abagovomab may stimulate the host immune system to mount an antibody response and subsequent antibody-dependent cell-mediated cytotoxicity response against CA125 positive tumor cells, thereby decreasing tumor growth. (NCI04) ( NCI )] (UMLS (NCI) C1327946) Monoclonal Antibody ACA125 Anti-Idiotype Vaccine =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 84. ABDMNAL MASS PERIUMBILIC
- [ ] (UMLS (ICD9CM) C0375561) =Sign or Symptom
|
- 35. abalone
- [ ] (UMLS (CSP) C0598488) =Invertebrate ;
| - 85. ABDMNAL MASS RT LWR QUAD
- [ ] (UMLS (ICD9CM) C0375559) =Sign or Symptom
|
- 36. Abandonment or neglect of infants and helpless persons
- [ ] (UMLS (ICD9CM) C0261659) =Human-caused Phenomenon or Process
| - 86. ABDMNAL MASS RT UPR QUAD
- [ ] (UMLS (ICD9CM) C0375557) =Sign or Symptom
|
- 37. Abasic Site Formation
- [Abasic Site Formation involves the creation of an apurinic or apyrimidinic site resulting from the loss of a purine or pyrimidine residue from DNA. ( NCI )] (UMLS (NCI) C1510710) Formation of Abasic Site;
=Cell or Molecular Dysfunction | - 87. ABDMNAL MASS UNSPCF SITE
- [ ] (UMLS (ICD9CM) C0375556) =Sign or Symptom
|
- 38. Abatement of event after product withdrawn
- (UMLS (HL7) C1546994) =Idea or Concept =Causality Observations;
| - 88. ABDMNAL PAIN EPIGASTRIC
- [ ] (UMLS (ICD9CM) C0232493) =Sign or Symptom
|
- 39. Abbokinase
- (UMLS (NCI) C0701941) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Enzyme ;
| - 89. ABDMNAL PAIN GENERALIZED
- [ ] (UMLS (ICD9CM) C0344304) =Sign or Symptom ;
|
- 40. Abbott 40566
- (UMLS (NCI) C0740167) =Organic Chemical; Pharmacologic Substance ;
| - 90. ABDMNAL PAIN LFT UP QUAD
- (UMLS (ICD9CM) C0238552) =Sign or Symptom
|
- 41. Abbott Laboratories
- (UMLS (HL7) C1546858) =Health Care Related Organization =Manufacturers of Vaccines (code=MVX);
| - 91. ABDMNAL PAIN LT LWR QUAD
- (UMLS (ICD9CM) C0238551) =Sign or Symptom
|
- 42. Abbott Laboratories (includes Ross Products Division)
- [Abbott Laboratories (includes Ross Products Division) ( HL7V3.0 )] (UMLS (HL7) C1552881) =Health Care Related Organization =VaccineManufacturer;
| - 92. ABDMNAL PAIN OTH SPCF ST
- [ ] (UMLS (ICD9CM) C0375555) =Sign or Symptom
|
- 43. Abbott-56268
- (UMLS (NCI) C0701282) =Organic Chemical; Antibiotic
| - 93. ABDMNAL PAIN PERIUMBILIC
- [ ] (UMLS (ICD9CM) C1096624) Abdominal pain, periumbilic =Sign or Symptom ;
|
- 44. ABBP-1
- [Heterogeneous Nuclear Ribonucleoprotein A/B, encoded by the HNRPAB gene, belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and they form a component of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It acts as the catalytic component of the multiprotein editosome complex which mediates apolipoprotein B mRNA editing. Two alternatively spliced transcript variants has been described for this gene which encode different isoforms. (from LocusLink) ( NCI )] (UMLS (NCI) C0534522) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 94. ABDMNAL PAIN RT LWR QUAD
- [ ] (UMLS (ICD9CM) C0740603) Abdominal pain, right lower quadrant =Sign or Symptom ;
|
- 45. Abbreviation
- [A shortened form of a word or phrase. ( NCI )] (UMLS (NCI) C0000723) =Intellectual Product ;
| - 95. ABDMNAL PAIN RT UPR QUAD
- [ ] (UMLS (ICD9CM) C0235299) =Sign or Symptom
|
- 46. ABC test
- [ ] (UMLS (CSP) C0597877) =Laboratory Procedure ;
| - 96. ABDMNAL PAIN UNSPCF SITE
- [Sensation of discomfort, distress, or agony in the abdominal region; generally associated with functional disorders, tissue injuries, or diseases. ( MSH )] (UMLS (ICD9CM) C0000737) =Sign or Symptom
|
- 47. ABC Transport Protein
- [ABC transporters consist of two integral membrane proteins (permeases) each having six transmembrane segments, two peripheral membrane proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. The ATP-binding protein component is the most conserved, the membrane protein component is somewhat less conserved, and the substrate-binding protein component is most divergent. ( NCI )] (UMLS (NCI) C0242738) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 97. ABDMNAL RGDT EPIGASTRIC
- [ ] (UMLS (ICD9CM) C0375570) =Sign or Symptom
|
- 48. ABC Transporter Binding
- [ABC Transporter Binding involves temporary non-covalent interaction of a molecule through intermolecular physical forces of attraction with a protein complex that, after conformational change, moves a bound substrate across a cell membrane against a concentration gradient resulting directly from the expenditure of energy. ABC Transporter complexes consist of two conserved six-transmembrane proteins (permeases), two conserved ATP-hydrolyzing peripheral membrane proteins, and a periplasmic substrate-binding protein. ( NCI )] (UMLS (NCI) C1510679) =Molecular Function ;
| - 98. ABDMNAL RGDT GENERALIZED
- [ ] (UMLS (ICD9CM) C0375571) =Sign or Symptom
|
- 49. ABC Transporter, MHC 1
- [Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP), encoded by the TAP1 gene, is a member of the superfamily of ATP-binding cassette (ABC) transporters. Being a member of the MDR/TAP subfamily and a subunit of the heterodimeric TAP1/TAP2 complex (TAP), this protein is involved in antigen processing. TAP transports peptides from the cytoplasm to the endoplasmic reticulum for assembly of MHC class I molecules. Loss of TAP function occurs more often in metastatic than in primary tumors. Loss of TAP1 expression may enhance tumor growth by enabling them to escape T-cell recognition during the effector phase of an antitumor immune response in immunized mice. However, it does not change the immunogenicity of tumor cells in the priming phase. Mutations in the TAP1 gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. (From LocusLink 6890, PMID 12019164 and NCI) ( NCI )] (UMLS (NCI) C0140599) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 99. ABDMNAL RGDT LFT UP QUAD
- [ ] (UMLS (ICD9CM) C0375566) =Sign or Symptom
|
- 50. ABC Transporter, MHC 2
- [Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP), encoded by the TAP2 gene, is a member of the superfamily of ATP-binding cassette (ABC) transporters. Being a member of the MDR/TAP subfamily and a subunit of the heterodimeric TAP1/TAP2 complex (TAP), this protein is involved in antigen processing. TAP transports peptides from the cytoplasm to the endoplasmic reticulum for assembly of MHC class I molecules. Loss of TAP function occurs more often in metastatic than in primary tumors. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. (From LocusLink 6891, PMID 11773612 and NCI) ( NCI )] (UMLS (NCI) C0165949) =Amino Acid, Peptide, or Protein; Immunologic Factor
| - 100. ABDMNAL RGDT LT LWR QUAD
- [ ] (UMLS (ICD9CM) C0375568) =Sign or Symptom
|