- 1. ATP
- [ATPase, Aminophospholipid Transporter-Like, Class I, Type 8A, Member 2, encoded by the ATP8A2 gene, is an integral membrane protein has similarity to P-type ATPases, proteins that drive uphill transport of ions across membranes. Transfection of antisense constructs into a nontumorigenic cell line rendered the cells tumorigenic in nude mice. (from Swiss-Prot and OMIM) ( NCI )] (UMLS (NCI) C1366832) ATP8A2;
ATPase, Aminophospholipid Transporter-Like, Class I, Type 8A, Member 2;
ATPIB;
DKFZP434B1913;
IB;
ML-1;
ML-1 Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 8. ATP-dependent DNA helicase II
- [Encoded by Ku Subunit Genes, tightly-associated 70-kDa Ku70 Protein and 80-kDa Ku80 Protein are subunits of heterodimeric DNA-binding Ku Protein, a DNA damage repair complex that, with the 470-kDa catalytic DNA-PKcs subunit forms DNA-dependent protein kinase, binds and repairs double-stranded DNA breaks, facilitates repair by nonhomologous end-joining, and is involved in V(D)J recombination. Ku also binds to DNA ends with a telomere binding protein and mediates telomere capping to prevent fusion of chromosome ends and genetic instability. KU70 and KU80 form a dyad-symmetrical ring molecule that encircles duplex DNA. Ku is identical to DNA helicase II, an ATP-dependent DNA unwinding enzyme. (NCI) ( NCI )] (UMLS (NCI) C1337080) Ku Protein =Amino Acid, Peptide, or Protein; Enzyme ;
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- 2. ATP biosynthesis (oxidative)
- [electron transfer through the cytochrome system liberating free energy which is transformed into high-energy phosphate bonds. ( CSP )] (UMLS (CSP) C0030013) =Molecular Function ;
=aerobiosis;
phosphorylation | - 9. ATP-Dependent DNA Helicase II, 70 kD Subunit
- [KU70 protein is the 70 kD subunit of the KU autoantigen, a heterodimeric DNA repair complex that binds DNA double-strand breaks, is the DNA-binding component of the DNA-dependent protein kinase, and facilitates repair by nonhomologous end-joining. KU70 and KU80 form a dyad-symmetrical molecule with a preformed ring that encircles duplex DNA. KU protein is also involved in V(D)J recombination. KU is identical to DNA helicase II, an ATP-dependent DNA unwinding enzyme. (from OMIM 152690 and NCI) ( NCI )] (UMLS (NCI) C1311257) G22P1;
Ku70 Protein;
La Protein;
Lupus Autoantigen;
Lupus Ku Autoantigen;
Thyroid Autoantigen 70kD =Amino Acid, Peptide, or Protein; Enzyme ;
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- 3. ATP citrate (pro3s) lyase
- [An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8. ( MSH )] (UMLS (CSP) C0004199) =Amino Acid, Peptide, or Protein; Enzyme
| - 10. ATP-Dependent DNA Helicase II, 86 kD Subunit
- [KU80 protein is the 80 kD subunit of the KU autoantigen, a heterodimeric DNA repair complex that binds DNA double-strand breaks, is the DNA-binding component of the DNA-dependent protein kinase, and facilitates repair by nonhomologous end-joining. KU70 and KU80 form a dyad-symmetrical molecule with a preformed ring that encircles duplex DNA. KU protein is also involved in V(D)J recombination. KU is identical to DNA helicase II, an ATP-dependent DNA unwinding enzyme. (from OMIM 194364 and NCI) ( NCI )] (UMLS (NCI) C0064435) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 4. ATP Hydrolysis
- [ATP Hydrolysis is the cleavage of a high-energy phosphate bond of adenosine triphosphate by the addition of water. The energy derived from hydrolysis of ATP is used to drive metabolic reactions including nucleic acid and protein synthesis, to move molecules against concentration gradients (active transport), and to produce mechanical motion (contraction of microfibrils and microtubules). ( NCI )] (UMLS (NCI) C1510699) =Molecular Function ;
| - 11. ATP-Dependent Helicase DDX1
- [Encoded by human DDX1 Gene and highly expressed in neuroectodermal tissues, 740-amino acid 82.4-kD DEAD/H Box Protein 1 has unknown function, contains a SPRY domain, and belongs to the DEAD/H box ATP-dependent RNA helicase family. DEAD box proteins, characterized by the conserved Asp-Glu-Ala-Asp (DEAD) motif, are putative RNA helicases that alter RNA secondary structure and influence translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on distribution, some family members may be involved in embryogenesis, spermatogenesis, and cellular growth and division. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0252684) =Amino Acid, Peptide, or Protein; Enzyme
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- 5. ATP phosphohydrolase (Na+ K+ transporting)
- [family of ouabain-sensitive, ATP-driven, transmembrane molecular pumps which maintain opposing concentration gradients of sodium and potassium across cell membranes term not valid for FY 92. ( CSP )] (UMLS (CSP) C0001479) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 12. ATP-Dependent RNA Helicase 3
- [Encoded by human DDX16 Gene (DEAD/H Subfamily, member 16), ubiquitous 1041-amino acid 119.3-kD nuclear DEAD/H Box Protein 16 is a functional homolog of the Prp8/cdc28 cell cycle progression protein (S. pombe), similar to DEAH box proteins that act as splicing factors. DBP2 is a probable ATP-binding RNA helicase involved in pre-mRNA splicing. DEAD box proteins, characterized by a conserved Asp-Glu-Ala-Asp (DEAD) motif, are putative RNA helicases that alter RNA secondary structure and influence translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on distribution, some family members may be involved in embryogenesis, spermatogenesis, and cellular growth and division. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1333211) DBP2;
DDX16;
DDX16 Protein;
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 16;
DEAD/H Box 16;
DEAD/H Box Protein 16;
DEAH-Box Protein 16;
DEAH-Box Protein 2;
PRP8 Homolog;
Putative Pre-mRNA Splicing Factor RNA Helicase =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 6. ATP receptor
- [ ] (UMLS (CSP) C0004204) =Amino Acid, Peptide, or Protein; Receptor
| - 13. ATP8A2
- [This gene plays a role in cellular transport. It is purported to be involved in the modulation of amphipathic transporters and their activities. ( NCI )] (UMLS (NCI) C1366628) ATP8A2 Gene;
ATPase, Aminophospholipid Transporter-Like, Class I, Type 8A, Member 2 Gene =Gene or Genome |
- 7. ATP Synthesis
- (UMLS (NCI) C1510700) ATP Synthesis Pathway;
=Functional Concept ;
| - 14. ATPase Domain
- [A protein domain that binds ATP and catalyzes its convertion to ADP and inorganic phosphate. ( NCI )] (UMLS (NCI) C1510701) =Amino Acid Sequence ;
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