- 701. 12
- [Maxillary left first premolar ( HL7V3.0 )] (UMLS (HL7) C0227047) tooth 12 =Body Part, Organ, or Organ Component =Permanent dentition;
| - 751. 14a
- [Maxillary left first molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553646) =Medical Device =Artificial dentition;
|
- 702. 12 hours
- (UMLS (HL7) C1292430) =Temporal Concept ;
=Duration categories;
| - 752. 14G2A
- [A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity. Monoclonal antibody 14G2A binds to the ganglioside GD2 and induces antibody-dependent cell mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. (NCI04) ( NCI )] (UMLS (NCI) C0280838) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 703. 12 hours post challenge
- (UMLS (HL7) C1547063) =Temporal Concept =Time delay post challenge;
| - 753. 14i
- [Maxillary left first molar implant ( HL7V3.0 )] (UMLS (HL7) C1552178) =Medical Device =Artificial dentition;
|
- 704. 12-20 years old
- [period of life beginning with the appearance of secondary sex characteristics and terminating with the cessation of somatic growth; typically between 12 and 20 years of age; when school grades are referenced, this age group is typically grade 5 or 6 and above; also index with appropriate human and clinical research terms. ( CSP )] (UMLS (CSP) C0001578) =Temporal Concept ;
| - 754. 14p
- [Maxillary left first molar prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553577) =Body Part, Organ, or Organ Component =Artificial dentition;
|
- 705. 12-Allyldeoxoartemisinin
- [A semi-synthetic analogue of Artemisinin - a sesquiterpene lactone extracted from the dry leaves of Artemisia Annua (sweet wormwood) used as anti-malaria agent. Limited data is available on Artemisinin antineoplastic activity. ( NCI )] (UMLS (NCI) C0294412) =Organic Chemical; Pharmacologic Substance ;
| - 755. 14pd
- [Maxillary left first molar distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553578) =Medical Device =Artificial dentition;
|
- 706. 12-HETE
- [A lipoxygenase metabolite of arachidonic acid. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (MeSH) ( NCI )] (UMLS (NCI) C0044800) =Eicosanoid; Biologically Active Substance ;
| - 756. 14pm
- [Maxillary left first molar mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553576) =Medical Device =Artificial dentition;
|
- 707. 12-O-tetradecanoylphorbol-13-acetate
- [A drug that is being studied as a treatment for hematologic cancer. ( NCI )] (UMLS (NCI) C0039654) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 757. 14q
- [Distal (long) arm of chromosome 14 ( NCI )] (UMLS (NCI) C1327813) Chromosome 14 Distal Arm;
Chromosome 14 Long Arm;
Chromosome 14q =Nucleotide Sequence ;
|
- 708. 125-Iodine
- [A radioactive isotope of iodine, a nonmetallic element of the halogen group. With a half-life of 60 days, iodine 125 occurs naturally and can be produced artificially. This agent has both therapeutic and diagnostic uses, particularly in thyroid disease. (NCI04) ( NCI )] (UMLS (NCI) C0796396) I-125;
I125 isotope;
Iodine 125;
Iodine I 125;
Iodine I-125;
IODINE,I-125;
IODINE,I-125 PREPARATION;
=Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope =I;
Inactive Ingredient Preparations =IODINE,I-125 0.01 MIC | - 758. 14s
- [Supernumerary maxillary left first molar ( HL7V3.0 )] (UMLS (HL7) C1552128) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 709. 125-L-Serine-2-133-interleukin 2
- [A laboratory-made colony-stimulating factor that stimulates the production of blood cells, especially platelets, during chemotherapy. It is a cytokine that belongs to the family of drugs called hematopoietic (blood-forming) agents. Also called interleukin-2 or IL-2. ( NCI )] (UMLS (NCI) C0218986) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=[IM700] IMMUNE STIMULANTS;
Recombinant Protein =ALDESLEUKIN 22 MILLION UNT/VIL | - 759. 15
- [Maxillary left second molar ( HL7V3.0 )] (UMLS (HL7) C0227052) tooth 15 =Body Part, Organ, or Organ Component =Permanent dentition;
|
- 710. 12a
- [Maxillary left first premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553644) =Medical Device =Artificial dentition;
| - 760. 15 day report
- (UMLS (HL7) C1546918) =Temporal Concept =Report timing;
|
- 711. 12i
- [Maxillary left first premolar implant ( HL7V3.0 )] (UMLS (HL7) C1552176) =Medical Device =Artificial dentition;
| - 761. 15 minutes post challenge
- (UMLS (HL7) C1547064) =Temporal Concept =Time delay post challenge;
|
- 712. 12p
- [Maxillary left first premolar prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553571) =Body Part, Organ, or Organ Component =Artificial dentition;
| - 762. 15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 3-((1E)-2-((1R,3R,4S)-4-chloro-3-methoxycyclohexyl)-1-methylethenyl)-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,1
- [A 33-epi-chloro-derivative of the ascomycin macrolactam with immunosuppressant property. Pimecrolimus binds to the receptor macrophilin-12 (FKBP-12) forming a complex that blocks the calcium-dependent signal transduction cascade mediated by calcineurin. Via dephosphorylation, calcineurin is the enzyme responsible for activating nuclear factor of activated T-cells (NF-AT), a T cell transcriptional regulatory factor. As a consequence, the synthesis and release of Th1- (T helper 1) and Th2- (T helper 2) type cytokines, and other inflammatory mediators from T-cells and mast cells are blocked and the expression of signals essential for the activation of inflammatory T-lymphocytes is inhibited. However, pimecrolimus mode of action is cell-selective and does not affect Langerhans' cells/dendritic cells and primary fibroblasts. ( NCI )] (UMLS (NCI) C1099414) 33-epi-Chloro-33-desoxyascomycin;
PIMECROLIMUS;
PIMECROLIMUS UNIDENTIFIED;
PIMECROLIMUS PREPARATION;
PIMECROLIMUS UNIDENTIFIED =Organic Chemical; Pharmacologic Substance =[DE900] DERMATOLOGICALS, TOPICAL OTHER;
Unclassified Ingredients =PIMECROLIMUS 1 % |
- 713. 12pd
- [Maxillary left first premolar distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553572) =Medical Device =Artificial dentition;
| - 763. 15-Deoxyspergualin Hydrochloride
- (UMLS (NCI) C0284558) =Organic Chemical; Pharmacologic Substance ;
|
- 714. 12pm
- [Maxillary left first premolar mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553570) =Medical Device =Artificial dentition;
| - 764. 15-Lipoxygenase, Reticulocyte Arachidonate
- [Encoded by human ALOX15 Gene, a putative mutator gene regulated by tumor-suppressor TP53, 661-amino acid 74.7 kD cytoplasmic Arachidonate 15-Lipoxygenase (Lipoxygenase Family) acts in leukotriene biosynthesis and is implicated in anti-inflammation, membrane remodeling, and cancer development or metastasis. It converts arachidonic acid to 15s-hydroperoxyeicosatetraenoic acid. (OMIM, Swiss-Prot, and NCI) ( NCI )] (UMLS (NCI) C0003692) =Amino Acid, Peptide, or Protein; Enzyme
|
- 715. 12s
- [Supernumerary maxillary left first premolar ( HL7V3.0 )] (UMLS (HL7) C1552126) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
| - 765. 150 kD Oxygen-Regulated Protein
- [Highly expressed in secretory tissues (liver and pancreas) by human HYOU1 Gene (HSP70 Family), hypoxia-induced 999-aa (precursor) 150 kD Hypoxia Up-Regulated 1 Protein is an endoplasmic reticulum cytoprotectant in oxygen deprivation that may act as a chaperone with GRPs and participate in protein folding and secretion. ORP150 contains a C-terminal KNDEL sequence and N-terminal similarity to HSP70 ATPase domain. ORP150 suppression is associated with accelerated apoptosis. ORP150 expression in neurons suppresses caspase-3-like activity and enhances BDNF under hypoxia signaling. Elimination of the signal peptide through an alternative translation site may generate a cytosolic housekeeping protein. (NCI) ( NCI )] (UMLS (NCI) C0377954) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 716. 13
- [Maxillary left second premolar ( HL7V3.0 )] (UMLS (HL7) C0227048) tooth 13 =Body Part, Organ, or Organ Component =Permanent dentition;
| - 766. 153Sm-EDTMP
- (UMLS (NCI) C0772051) Samarium Sm 153 Lexidronam;
Samarium Sm-153 EDTMP;
Samarium-153 EDTMP;
Samarium-153 Ethylenediaminetetramethylenephosphonate;
Samarium-153 Ethylenediaminetetramethylenephosphonic Acid;
Sm-153 EDTMP =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid |
- 717. 13 cis retinoate
- [a topical dermatologic agent that is used in the treatment of acne vulgaris and several other skin diseases. ( CSP )] (UMLS (CSP) C0022265) =Organic Chemical; Pharmacologic Substance =Retinoic Acid Agent;
retinoate;
[DE751] ANTIACNE AGENTS, SYSTEMIC;
=ISOTRETINOIN 10 MG;
ISOTRETINOIN 40 MG;
ISOTRETINOIN 20 MG;
| - 767. 1592U89
- (UMLS (NCI) C0540137) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=Dideoxynucleosides;
=Abacavir |
- 718. 13-(N,N-Dimethylglycyl)brefeldin A
- [A water soluble analogue of the antineoplastic agent brefeldin A (BFA). (NCI04) ( NCI )] (UMLS (NCI) C0760968) Breflate =Organic Chemical; Pharmacologic Substance ;
| - 768. 15a
- [Maxillary left second molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553647) =Medical Device =Artificial dentition;
|
- 719. 13-CRA/5-FU/IFN-A/IL-2
- (UMLS (NCI) C0338195) =Therapeutic or Preventive Procedure ;
| - 769. 15H-Pyrrolol[2,1-f][1,15,4,7,10,20]dioxatetraazacyclotri-cosine, Cyclic Peptide Deriv. (9CI)
- [A cyclic depsipeptide extracted from the Caribbean tunicate Trididemnum cyanophorum. Didemnin B activates caspase, thereby inducing apoptosis, and prevents eukaryotic elongation factor 2 (eEF-2)-dependent translocation, thereby inhibiting protein synthesis. This agent also has immunosuppressive and antiviral properties. (NCI04) ( NCI )] (UMLS (NCI) C0936059) 1-Oxoheptyl]oxy]-2,5-dimethyl-1,3-dioxohexyl]-L-leucyl]- L-prolyl]-N,O-dimethyl-, .phi.-lactone (9CI);
Didemnin;
Didemnin B;
L-Tyrosine, N-[1-[N-[4-[[3-hydroxy-4-[[N-[N-[1-(2-hydroxy-1-oxopropyl)- L-prolyl]-N-methyl-L-leucyl]-L-threonyl]amino-5-methyl- 1-oxoheptyl]oxy]-2,5-dimethyl-1,3-dioxohexyl]-L-leucyl]- L-prolyl]-N,O-dimethyl-, .phi.-lactone (9CI);
L-Tyrosine, N-[1-[N-[4-[[3-Hydroxy-4-[[N-[N-[1-(2-hydroxy-1-oxopropyl)- L-prolyl]-N-methyl-L-leucyl]-L-threonyl]amino-5-methyl-1-oxoheptyl]oxy]-2,5-dimethyl-1,3-dioxohexyl]-L-leucyl]- L-prolyl]-N,O-dimethyl-, .phi.-lactone (9CI);
=Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
|
- 720. 13-CRA/FLUT/LEUP
- (UMLS (NCI) C0281718) =Therapeutic or Preventive Procedure
| - 770. 15i
- [Maxillary left second molar implant ( HL7V3.0 )] (UMLS (HL7) C1552179) =Medical Device =Artificial dentition;
|
- 721. 13-CRA/IFN-A
- (UMLS (NCI) C0338122) =Therapeutic or Preventive Procedure ;
| - 771. 15p
- [Maxillary left second molar prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553580) =Body Part, Organ, or Organ Component =Artificial dentition;
|
- 722. 13-CRA/IFN-A/IL-2
- (UMLS (NCI) C0338194) =Therapeutic or Preventive Procedure ;
| - 772. 15pd
- [Maxillary left second molar distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553581) =Medical Device =Artificial dentition;
|
- 723. 13-CRA/IFN-A/VIT-E
- (UMLS (NCI) C0678004) =Therapeutic or Preventive Procedure
| - 773. 15pm
- [Maxillary left second molar mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553579) =Medical Device =Artificial dentition;
|
- 724. 13-CRA/IFN-B
- (UMLS (NCI) C0281419) =Therapeutic or Preventive Procedure
| - 774. 15s
- [Supernumerary maxillary left second molar ( HL7V3.0 )] (UMLS (HL7) C1552129) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 725. 13-CRA/PCB
- (UMLS (NCI) C0796376) Isotretinoin/Procarbazine =Therapeutic or Preventive Procedure ;
| - 775. 16
- [Maxillary left third molar ( HL7V3.0 )] (UMLS (HL7) C0227053) tooth 16 =Body Part, Organ, or Organ Component =Permanent dentition;
|
- 726. 13-CRA/TMZ
- (UMLS (NCI) C0796607) Isotretinoin/Temozolomide =Therapeutic or Preventive Procedure
| - 776. 16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure
- [A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect. ( NCI )] (UMLS (NCI) C0027444) =Organic Chemical; Antibiotic =macrolide antibiotic;
[OP202] ANTIFUNGALS, TOPICAL OPHTHALMIC =NATAMYCIN 5 %WV;
|
- 727. 13-CRA/VIT-E
- (UMLS (NCI) C0281667) =Therapeutic or Preventive Procedure
| - 777. 166 Holmium-DOTMP
- [A drug containing a radioactive isotope that is used in the diagnosis and treatment of cancer. ( NCI )] (UMLS (NCI) C1130449) Ho 166 DOTMP;
Holmium Ho 166 DOTMP;
=Organophosphorus Compound; Indicator, Reagent, or Diagnostic Aid |
- 728. 13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol
- [A synthetic progestogen with progesterone hormone receptor agonistic activity. Desogestrel binds intracellular progesterone receptors in progesterone responsive tissue and the resultant complex interacts with DNA and results in either gene transcription or gene repression. This leads to an inhibition of LH release and prevents ovulation and alters the cervical mucus. Desogestrel is used in birth control pills alone or in combination with estrogens. ( NCI )] (UMLS (NCI) C0057558) =Steroid; Pharmacologic Substance; Hormone =Norpregnenes;
[HS200] CONTRACEPTIVES, SYSTEMIC =DESOGESTREL 0.15 MG;
DESOGESTREL 0.1-0.15 MG;
DESOGESTREL 0.15-0.2 MG | - 778. 16a
- [Maxillary left third molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553648) =Medical Device =Artificial dentition;
|
- 729. 13-Hydroxydaunomycin
- [An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Duborimycin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0057159) =Organic Chemical; Pharmacologic Substance ;
| - 779. 16alpha-Fluoroandrost-5-en-17-one
- (UMLS (NCI) C0539515) =Steroid; Pharmacologic Substance ;
|
- 730. 130 kDa Retinoblastoma-Associated Protein
- [Expressed only in G0 by human RBL2 Gene (RB Family), 1139-aa 128-kDa nuclear Retinoblastoma-Like 2 protein binds to adenovirus E1A protein and to cyclins A and E, associates preferentially with E2F5, inhibits E2F-mediated trans-activation, and may function in cell cycle regulation. Ser-672 phosphorylation in G1 leads to ubiquitin-dependent proteolysis of RBL2. (NCI) ( NCI )] (UMLS (NCI) C0249759) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 780. 16i
- [Maxillary left third molar implant ( HL7V3.0 )] (UMLS (HL7) C1552180) =Medical Device =Artificial dentition;
|
- 731. 131 I-MIBG
- [An I 131 radioiodinated synthetic analogue of the neurotransmitter norepinephrine. Meta-iodobenzylguanidine localizes to adrenergic tissue and, in radioiodinated forms, may be used to image or eradicate tumor cells that take up and metabolize norepinephrine. ( NCI )] (UMLS (NCI) C0879568) I 131 Metaiodobenzylguanidine;
I 131 Meta-iodobenzylguanidine;
Iodine I 131 Metaiodobenzylguanidine;
=Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid | - 781. 16p
- [Maxillary left third molar prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553583) =Body Part, Organ, or Organ Component =Artificial dentition;
|
- 732. 131-I-Anti-B1 Monoclonal Antibody
- [A monoclonal antibody directed against a protein (CD20) expressed on the surface of B-lymphocytes and radiolabeled with the radioisotope I 131 with potential antineoplastic activity. Iodine 131 tositumomab delivers radiation selectively to neoplastic CD20-expressing B-lymphocytes cells, thereby decreasing the risk of systemic radiotoxicity. ( NCI )] (UMLS (NCI) C0768182) I 131 Bexxar;
I 131 Monoclonal Antibody Anti-B1;
I 131 Tositumomab;
I131-MOAB-B1;
Iodine I 131 MOAB Anti-B1;
Iodine I 131 Monoclonal Antibody Anti-B1;
Iodine I 131 Tositumomab;
Iodine-131 Anti-B1 Antibody;
Iodine-131 Anti-CD20 Monoclonal Antibody;
Iodine-131 Tositumomab;
TOSITUMOMAB IODINE-131;
TOSITUMOMAB IODINE-131 PREPARATION =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =anti-B1;
Unclassified Ingredients =TOSITUMOMAB IODINE-131 0.61 MCI/ML;
TOSITUMOMAB IODINE-131 VIAL 5.6MCI/ML | - 782. 16pd
- [Maxillary left third molar distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553584) =Medical Device =Artificial dentition;
|
- 733. 131-Iodine
- [A radioactive isotope of iodine with an atomic mass of 131, a half life of eight days, and potential antineoplastic activity. Selectively accumulating in the thyroid gland, iodine I 131 emits beta and gamma particles, thereby killing thyroid cells and decreasing thyroid hormone production. ( NCI )] (UMLS (NCI) C0303029) =Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope
| - 783. 16pm
- [Maxillary left third molar mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553582) =Medical Device =Artificial dentition;
|
- 734. 131I-HuCC49-deltaCH2
- [A radioimmunoconjugate consisting of the humanized monoclonal antibody (MoAb) CC49 having CH2 domain deleted, labeled with iodine 131 (I-131). MoAb CC49-deltaCH2 recognizes an epitope of the tumor-associated glycoprotein (TAG) 72 that is expressed by a wide range of cancers, including colorectal, gastric, pancreatic, ovarian, endometrial, breast, non-small cell lung, and prostate cancers. I-131 MoAb CC49-delta CH2 delivers beta and gamma radiation emitting I-131 nuclide directly to tumor cells that express TAG-72, thereby allowing imaging and/or treatment of cancers. ( NCI )] (UMLS (NCI) C1134477) 131I-MOAB CC49-deltaCH2;
I131 MOAB CC49-deltaCH2;
Iodine I 131 Monoclonal Antibody CC49-deltaCH2 =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor | - 784. 16s
- [Supernumerary maxillary left third molar ( HL7V3.0 )] (UMLS (HL7) C1552130) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 735. 131I-mAbF19
- [A radioimmunoconjugate of a murine monoclonal antibody (MoAb) F19 labelled with Iodine 131 (I-131). MoAb F19 was raised against fibroblast activation protein (FAP), which is highly expressed by tumor stromal cells. Using MoAb F19 as a carrier for I-131 results in the targeted imaging and/or destruction of cells overexpressed FAP. ( NCI )] (UMLS (NCI) C0796525) I 131 Monoclonal Antibody F19;
Iodine I 131 Monoclonal Antibody F19;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor | - 785. 17
- [Mandibular left third molar ( HL7V3.0 )] (UMLS (HL7) C0227054) tooth 17 =Body Part, Organ, or Organ Component =Permanent dentition;
|
- 736. 13a
- [Maxillary left second premolar abutment ( HL7V3.0 )] (UMLS (HL7) C1553645) =Medical Device =Artificial dentition;
| - 786. 17 Alpha-methyl-delta4-androsten-17beta-ol-4-one
- (UMLS (NCI) C1449554) =Steroid; Pharmacologic Substance
|
- 737. 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido(3',2':14,15)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolinium
- [The chloride salt form of tubocurarine, a naturally occurring curare alkaloid isolated from the bark and stem of Chondodendron tomentosum with a muscle relaxant property. Tubocurarine chloride competes with acetylcholine for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This may lead to skeletal muscle relaxation and paralysis. ( NCI )] (UMLS (NCI) C0282372) =Organic Chemical; Pharmacologic Substance ;
=Tubocurare;
=TUBOCURARINE CHLORIDE 3 MG/ML;
| - 787. 17 Beta-hydroxy-2 alpha-methyl-5 alpha-androstan-3-one
- (UMLS (NCI) C0960041) 2 Alpha-5 alpha-17 beta-17-hydroxy-2-methyl-androstan-3-one;
2 Alpha-methylandrostan-17 beta-ol-3-one;
2 Alpha-methyldihydrotestosterone;
2.alpha.-Methyldihydrotestosterone;
5.alpha.-Androstan-3-one, 17.beta.-hydroxy-2.alpha.-methyl- =Steroid; Pharmacologic Substance |
- 738. 13i
- [Maxillary left second premolar implant ( HL7V3.0 )] (UMLS (HL7) C1552177) =Medical Device =Artificial dentition;
| - 788. 17 Beta-Hydroxysteroid Dehydrogenase Type 7
- [Encoded by human HSD17B7 Gene (SDR Family) and expressed in breast, ovaries, pregnant uterus, placenta, testis, thymus, prostate, fetal liver, and some neural tissues, 341-amino acid 38-kD 17-Beta-Hydroxysteroid Dehydrogenase 7 oxidizes or reduces estrogens and androgens. Responsible for biosynthesis of estradiol in the corpus luteum during pregnancy, the membrane-associated phosphorylated enzyme is nearly 75% identical to rodent proteins and contains a short chain dehydrogenase domain. Close to the transmembrane domain, HSD17B7 contains a 28-residue superficial loop: a candidate prolactin receptor (PRLR)-binding domain. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1334066) 17 Beta-Hydroxysteroid Dehydrogenase Type VII;
17-Beta-HSD 7;
17-Beta-Hydroxysteroid Dehydrogenase 7;
EC 1.1.1.51;
Estradiol 17 Beta-Dehydrogenase 7;
HSD17B7;
Hydroxysteroid (17-Beta) Dehydrogenase 7 =Amino Acid, Peptide, or Protein; Enzyme |
- 739. 13p
- [Maxillary left second premolar prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553574) =Body Part, Organ, or Organ Component =Artificial dentition;
| - 789. 17 Beta-OH-7 beta, 17 alpha-dimethyl-androst-4-ene-3-one
- [A 17-alkylated orally active androgenic steroid. Calusterone may alter the metabolism of estradiol and reduce estrogen production. (NCI04) ( NCI )] (UMLS (NCI) C0006790) =Steroid; Pharmacologic Substance
|
- 740. 13pd
- [Maxillary left second premolar distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553575) =Medical Device =Artificial dentition;
| - 790. 17 hydroxycorticosteroid
- [A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of these compounds is used as an index of adrenal function. They are used systemically in the free alcohol form, but with esterification of the hydroxy groups, topical effectiveness is increased. ( MSH )] (UMLS (CSP) C0000163) =Steroid; Hormone ;
|
- 741. 13pm
- [Maxillary left second premolar mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553573) =Medical Device =Artificial dentition;
| - 791. 17,21-Dihydroxypregn-4-ene-3,11,20-trione
- [naturally occurring glucocorticoid used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent; cortisone itself is inactive and is converted in the liver to the active metabolite cortisol. ( CSP )] (UMLS (NCI) C0010137) =Steroid; Pharmacologic Substance; Hormone ;
=[HS051] GLUCOCORTICOIDS;
Pregnenes =21-(Acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione;
CORTISONE 25 MG;
|
- 742. 13s
- [Supernumerary maxillary left second premolar ( HL7V3.0 )] (UMLS (HL7) C1552127) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
| - 792. 17-(Acetyloxy)-6-chloropregna-4,6-diene-3,20-dione
- [An orally active synthetic progestational hormone used often in combinations as an oral contraceptive. ( MSH )] (UMLS (NCI) C0008214) =Steroid; Pharmacologic Substance ;
|
- 743. 14
- [Maxillary left first molar ( HL7V3.0 )] (UMLS (HL7) C0227051) tooth 14 =Body Part, Organ, or Organ Component =Permanent dentition;
| - 793. 17-(Allylamino)-17-demethoxygeldanamycin
- [A benzoquinone antineoplastic antibiotic derived from the antineoplastic antibiotic geldanamycin. Tanespimycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins; the inhibition of HSP90 promotes the proteasomal degradation of oncogenic signaling proteins that may be overexpressed by tumor cells. ( NCI )] (UMLS (NCI) C0675974) =Organic Chemical; Antibiotic ;
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- 744. 14 Carbon
- [An unstable isotope of carbon created when a neutron collides with a nitrogen atom, causing capture of the neutron and release of the proton converting nitrogen to a carbon with fourteen nucleons (6 protons and 8 neutrons). Carbon-14 emits beta particles as it decays and reverts back to nitrogen. ( NCI )] (UMLS (NCI) C0302945) =Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope ;
| - 794. 17-(Cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium
- [A methyl derivative of noroxymorphone with selective, opioid-receptor antagonistic activity. Methylnaltrexone displaces opioids from peripheral opioid receptors in the gastrointestinal tract, the bladder, and the skin, resulting in decreases in opioid-related constipation, urinary retention, and pruritis, respectively. Methylnaltrexone does not cross the blood-brain barrier and does not affect the centrally-mediated analgesic effect of opioids. ( NCI )] (UMLS (NCI) C0066411) =Organic Chemical; Pharmacologic Substance ;
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- 745. 14-3-3 Family
- [The 14-3-3 family of proteins mediates signal transduction by binding to phosphoserine-containing proteins. Two different binding motifs, RSXpSXP and RXY/FXpSXP, are present in nearly all known 14-3-3 binding proteins. The14-3-3 dimer binds tightly to single molecules containing tandem repeats of phosphoserine motifs, implicating bidentate association as a signaling mechanism with molecules such as Raf, BAD, and Cbl. (from OMIM) ( NCI )] (UMLS (NCI) C1337047) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 795. 17-Beta Hydroxysteroid Dehydrogenase
- [Expressed in many peripheral tissues (high in placenta) by human HSD17B2 Gene (SDR Family), 387-aa 43-kDa Hydroxysteroid 17-Beta Dehydrogenase 2 is a potential type II membrane protein enzyme with an N-terminal type II signal-anchor motif and a C-terminal ER retention motif, likely associated with ER membranes, that uses NADH in the oxidative inactivation metabolism of testosterone and androstenedione, as well as estradiol and estrone. HSD17B2 also has 3-beta-HSD activity and 20-alpha-HSD activity toward 20-alpha-dihydroprogesterone. (NCI) ( NCI )] (UMLS (NCI) C0014914) =Amino Acid, Peptide, or Protein; Enzyme ;
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- 746. 14-3-3 Protein Tau
- [Encoded by human YWHAQ Gene, 245-amino acid 27.8 kD YWHAQ Protein is a cytoplasmic homodimeric 14-3-3 family protein. 14-3-3 proteins are localized in neurons, and are axonally transported to the nerve terminals. 14-3-3 proteins may be present in other tissues as well. A probable multifunctional regulator of cell signaling processes, YWHAQ Protein strongly activates PKC and activates tyrosine and tryptophan hydroxylases in the presence of Ca(2+)/calmodulin-dependent protein kinase II. (Swiss-Prot, LocusLink, and NCI) ( NCI )] (UMLS (NCI) C1458135) 14-3-3 Protein T-Cell;
14-3-3 Protein Theta;
HS1 Protein;
Tyrosine 3/Tryptophan 5 -Monooxygenase Activation Protein, Theta Polypeptide;
Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Theta Polypeptide;
YWHAQ;
YWHAQ Protein;
=Amino Acid, Peptide, or Protein; Biologically Active Substance | - 796. 17-Demethoxy-15-methoxy-11-O-methylgeldanamycin, (15R)-
- [A benzoquinone antineoplastic antibiotic isolated from the bacterium Streptomyces hygroscopicus. Herbimycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins; the inhibition of HSP90 promotes the proteasomal degradation of oncogenic signaling proteins that may be over-expressed or overactive in tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0062565) =Organic Chemical; Antibiotic ;
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- 747. 14-3-3 Sigma
- [Stratifin was first identified as an epithelial cell antigen (HME-1) exclusively expressed in epithelia. The protein is a putative cytoplasmic, p53-regulated homodimeric inhibitor of G2/M progression that is over expressed in squamous cell carcinoma of the head and neck. The gene is a member of a large 14-3-3 gene family. ( NCI )] (UMLS (NCI) C0972212) Epithelial Cell Marker Protein 1;
SFN;
Stratifin =Amino Acid, Peptide, or Protein; Enzyme; Indicator, Reagent, or Diagnostic Aid | - 797. 17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic Acid, gamma Lactone, Acetate
- [potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules; used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis; its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. ( CSP )] (UMLS (NCI) C0037982) =Steroid; Pharmacologic Substance =aldosterone inhibitor;
LACTONE;
C21 steroid;
Pregnenes;
[CV704] POTASSIUM-SPARING/COMBINATIONS DIURETICS;
=SPIRONOLACTONE POWDER (GM);
SPIRONOLACTONE 100 MG;
SPIRONOLACTONE 25 MG;
SPIRONOLACTONE 50 MG;
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- 748. 14-Diethoxyacetoxydaunorubicin
- [A semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin. (NCI04) ( NCI )] (UMLS (NCI) C0057578) =Organic Chemical; Pharmacologic Substance ;
| - 798. 170-kD Melanoma Membrane-Bound Gelatinase
- [Expressed in fibroblasts similar to DPP4 and DPPX, inducible Fibroblast Activation Protein-Alpha major isoform 1 (Long, 760-aa, 87.8-kD) and truncated isoform 2 (Short, 239-aa) are encoded by human FAP Gene (Peptidase S9B Family). Heterodimeric (with DPP4) or homodimeric, N-glycosylated FAPA is a type II integral membrane protein gelatinase: 13 extracellular cysteine residues and 3 conserved serine protease domains, a transmembrane segment, and a short cytoplasmic tail. Monomer is inactive. On lamellipodia, FAPA appears involved in epithelial-mesenchymal interactions during development, tissue repair/remodeling, epithelial carcinogenesis, and malignant invasion. A product of the same gene, monomeric N-glycosylated Seprase is composed of proteolytically inactive subunits whose activities depend on subunit association. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0290024) =Amino Acid, Peptide, or Protein; Enzyme; Receptor
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- 749. 14-Hydroxydaunorubicin Hydrochloride
- [The hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects. ( NCI )] (UMLS (NCI) C0546861) =Organic Chemical; Pharmacologic Substance =(8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroacetyl)-1-methoxy-5,12-naphthacenedione;
=DOXORUBICIN HYDROCHLORIDE 10 MG;
DOXORUBICIN HYDROCHLORIDE 100 MG;
DOXORUBICIN HYDROCHLORIDE 150 MG;
DOXORUBICIN HYDROCHLORIDE 2 MG/ML;
DOXORUBICIN HYDROCHLORIDE 200 MG;
DOXORUBICIN HYDROCHLORIDE 50 MG;
DOXORUBICIN HYDROCHLORIDE 20 MG;
DOXORUBICIN HYDROCHLORIDE 5 MG/ML | - 799. 177 Lu-CC49
- [A radioimmunoconjugate of the humanized monoclonal antibody (MoAB) CC49 labeled with lutetium 131 (Lu-177). MoAb CC49 binds to the pancarcinoma tumor-associated glycoprotein (TAG)-72 with high affinity. Lu-177 MoAb CC49 delivers gamma radiation emitting Lu-177 nuclide directly to tumor cells that express TAG-72, thereby may be used in radioimmunotherapeutic treatment of cancers. ( NCI )] (UMLS (NCI) C0935675) Lutetium Lu 177 Monoclonal Antibody CC49;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 750. 141W94
- (UMLS (NCI) C0528367) =Organic Chemical; Pharmacologic Substance
| - 800. 17a
- [Mandibular left third molar abutment ( HL7V3.0 )] (UMLS (HL7) C1553649) =Medical Device =Artificial dentition;
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