- 1001. 2,4,5-Trihydroxyphenethylamine
- [neurotoxin used to induce experimental CNS and sympathetic neural lesions that model aging and various nervous disorders; also used to induce behavioral circling and as a potential antineoplastic for neuroblastoma. ( CSP )] (UMLS (NCI) C0085196) =Organic Chemical; Pharmacologic Substance =catecholamine;
Neurotoxin;
Dopamine Antagonist;
adrenergic antagonist | - 1051. 2-(p-Aminobenzenesulfonamido)-5-methylthiadiazole
- [A broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfamethizole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death. ( NCI )] (UMLS (NCI) C0038687) =Organic Chemical; Pharmacologic Substance =Sulfathiazoles;
[AM650] SULFONAMIDE/RELATED ANTIMICROBIALS =SULFAMETHIZOLE 250 MG;
SULFAMETHIZOLE 500 MG;
SULFAMETHIZOLE 0.5 GM;
SULFAMETHIZOLE 400 MG;
SULFAMETHIZOLE 800 MG;
|
- 1002. 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(2-Methylpropyl)-5-(2-propenyl)-
- [A barbiturate that exerts its effect by mimicking the inhibitory effect of gamma-aminobutyric acid (GABA) by binding to a site, distinct from the benzodiazepine binding site, on the GABA receptor. This leads to an increase in the duration of GABA-mediated opening of chloride channels and enhances the inhibitory effect of GABA. Consequently, its physiologic effects include sedation, hypnosis, reduction of anxiety, and respiratory depression and the drug causes tolerance and dependence. ( NCI )] (UMLS (NCI) C0054234) =Organic Chemical; Pharmacologic Substance =barbiturate;
[CN301] BARBITURIC ACID DERIVATIVE, SEDATIVES/HYPNOTICS =BUTALBITAL 50 MG;
BUTALBITAL 30 MG;
| - 1052. 2-(p-Aminophenyl)-2-ethylglutarimide
- [USP lists as an antineoplastic and an "adrenocortical suppressant." ( CSP )] (UMLS (NCI) C0002555) =Organic Chemical; Pharmacologic Substance ;
|
- 1003. 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-Ethyl-5-(1-methylbutyl), Monosodium Salt
- [The sodium salt of pentobarbital, a short-acting barbituric acid derivative with central nervous system (CNS) depressant property. Pentobarbital sodium binds to the gamma-aminobutyric acid (GABA)-A subtype receptor, resulting in modulation of chloride transport through receptor channels and potentiation of GABA-induced increases in chloride conductance. This enhances postsynaptic responses to the inhibitory actions of GABA and causes CNS depression. In addition, this agent inhibits glutamate induced nerve depolarization and depresses voltage-activated calcium currents. ( NCI )] (UMLS (NCI) C0700349) =Organic Chemical; Pharmacologic Substance ;
=PENTOBARBITAL;
=PENTOBARBITAL NA PWDR;
PENTOBARBITAL SODIUM 60 MG;
PENTOBARBITAL SODIUM 50 MG;
PENTOBARBITAL SODIUM 50 MG/ML;
PENTOBARBITAL SODIUM 30 MG;
PENTOBARBITAL SODIUM 120 MG;
PENTOBARBITAL SODIUM 100 MG;
PENTOBARBITAL SODIUM 200 MG;
PENTOBARBITAL SODIUM 20 MG/5ML | - 1053. 2-(p-Bromo-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine Maleate
- [The maleate salt form of brompheniramine, an alkylamine derivative and a histamine antagonist with anticholinergic and sedative properties. Brompheniramine maleate competes with histamine for the H1 receptor. This diminishes the actions of histamine on effector cells and decreases the histamine-mediated symptoms of allergic reaction such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle. ( NCI )] (UMLS (NCI) C0546853) =Organic Chemical; Pharmacologic Substance =BROMPHENIRAMINE;
=BROMPHENIRAMINE MALEATE 4 MG/5ML;
BROMPHENIRAMINE MALEATE 10 MG/ML;
BROMPHENIRAMINE MALEATE 12 MG;
BROMPHENIRAMINE MALEATE 6 MG;
BROMPHENIRAMINE MALEATE 2 MG/5ML;
BROMPHENIRAMINE MALEATE 4 MG;
BROMPHENIRAMINE MALEATE 2 MG;
|
- 1004. 2,4,6-Trichlorophenol
- [A synthetic, colorless crystalline solid that is slightly soluble in water and soluble in organic solvents. It has been used primarily in pesticide formulations and as a wood preservative, although most uses have been cancelled in the US. When heated to decomposition, 2,4,6-trichlorophenol emits toxic and corrosive fumes of hydrochloric acid and other toxic gases. Exposure of humans to 2,4,6-trichrophenol via inhalation has been reported to cause respiratory effects, altered pulmonary function and pulmonary lesions. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045437) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 1054. 2-(p-Chloro-alpha-(2-(dimethylamino)ethoxy)benzyl)pyridine Bimaleate
- [An ethanolamine class of H1 antihistamines with mild antimuscarinic and sedative properties. Carbinoxamine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries, and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscle. Carbinoxamine maleate is used to provide symptomatic relieve of allergic symptoms. ( NCI )] (UMLS (NCI) C0304300) =Organic Chemical; Pharmacologic Substance ;
=CARBINOXAMINE;
=CARBINOXAMINE MALEATE 2 MG/ML;
CARBINOXAMINE MALEATE 4 MG;
CARBINOXAMINE MALEATE 4 MG/5ML;
CARBINOXAMINE MALEATE 8 MG;
|
- 1005. 2,4,6-Tris(dimethylamino)-s-triazine
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0019453) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
triazine =ALTRETAMINE 50 MG | - 1055. 2-(Propylamino)-o-propionotoluidide Hydrochloride
- [The hydrochloride salt form of prilocaine, an intermediate-acting local anesthetic of the amide type chemically related to lidocaine. Prilocaine hydrochloride binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions. This leads to a stabilization of the neuronal membrane and inhibits depolarization and results in a reversible blockage of nerve impulse generation and propagation along nerve fibres and subsequent reversible loss of sensation. ( NCI )] (UMLS (NCI) C0008846) =Organic Chemical; Pharmacologic Substance =6,7-Epoxytropine Tropate;
=PRILOCAINE HYDROCHLORIDE 4 %;
|
- 1006. 2,4,D/2,4,5,T
- [(2,4-dichlorophenoxy)acetic acid, butyl ester, mixture with butyl (2,4,5-trichlorophenoxy)acetate; an herbicide and chemical defoliant. ( CSP )] (UMLS (NCI) C0050961) =Organic Chemical; Hazardous or Poisonous Substance =herbicide;
| - 1056. 2-.beta.-D-Ribofuranosyl-4-thiazolecarboxamide
- (UMLS (NCI) C0092663) =Organic Chemical; Pharmacologic Substance
|
- 1007. 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
- [antibacterial used in combination with a sulfonamide to treat some urinary tract infections and pneumocystis pneumonia, and alone as an antimalarial. ( CSP )] (UMLS (NCI) C0041041) =Organic Chemical; Pharmacologic Substance ;
=Pyrimidine;
antibacterial agent;
DAP;
[AM900] ANTI-INFECTIVES, OTHER =2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine Sulfate (2:1);
TRIMETHOPRIM 100 MG;
TRIMETHOPRIM 160 MG;
TRIMETHOPRIM 200 MG;
TRIMETHOPRIM 40 MG/5ML;
TRIMETHOPRIM 16 MG/ML;
TRIMETHOPRIM 80 MG;
TRIMETHOPRIM 50 MG/5ML;
| - 1057. 2-AAF
- [A synthetic, light tan crystalline solid that is insoluble in water and soluble in alcohols, glycols, ether, acetic acid, and fat solvents. It is used as a positive control by toxicologists to study the carcinogenicity and mutagenicity of aromatic amines. When heated to decomposition, 2-acetylaminofluorene emits toxic fumes of nitrogen oxides. The primary routes of potential human exposure to 2-acetylaminofluorene are inhalation and dermal contact. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0000248) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid; Hazardous or Poisonous Substance
|
- 1008. 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine Sulfate (2:1)
- [The sulfate salt form of trimethoprim, a synthetic substituted pyrimidine with antibacterial activity. Trimethoprim sulfate selectively binds to and reversibly inhibits dihydrofolate reductase, thereby blocking the production of tetrahydrofolic acid from dihydrofolic acid. This leads to an inhibition of bacterial synthesis of folic acid, thereby affecting nucleic acid and protein synthesis. Trimethoprim sulfate has a stronger binding affinity for the bacterial enzyme than for the corresponding mammalian enzyme. ( NCI )] (UMLS (NCI) C0724713) Trimethoprim Sulfate;
TRIMETHOPRIM SULFATE PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine;
=TRIMETHOPRIM SULFATE 0.1 % | - 1058. 2-Acetoxyethyltrimethylammonium Chloride
- [The chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride mimics the parasympathomimetic effect of the endogenous compound acetylcholine. Administered as an ophthalmic solution, this drug stimulates the cholinoceptors in the sphincter muscle of the iris, causing the pupil to constrict. (NCI05) ( NCI )] (UMLS (NCI) C0055389) =Organic Chemical; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine =acetylcholine;
=ACETYLCHOLINE CHLORIDE 1 %;
|
- 1009. 2,4-Diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline mono-D-glucuronate
- [A drug that belongs to the family of drugs called antimetabolites. It is used in the treatment of pneumocystis carinii pneumonia and is being studied in the treatment of cancer. ( NCI )] (UMLS (NCI) C0077209) =Organic Chemical; Pharmacologic Substance ;
| - 1059. 2-Amino 6MP
- [thioguanine is USP. ( CSP )] (UMLS (NCI) C0039902) =Organic Chemical; Pharmacologic Substance ;
=1,7-Dihydro-6H-purine-6-thione;
[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
[AN000] ANTINEOPLASTICS;
purine;
guanine analog;
=THIOGUANINE 40 MG |
- 1010. 2,4-Diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine
- [An anticancer drug. ( NCI )] (UMLS (NCI) C0054332) =Organic Chemical; Pharmacologic Substance ;
| - 1060. 2-Amino, 6-Methoxypurine Arabinoside
- [An arabinonucleoside antimetabolite with antineoplastic activity. Nelarabine is demethoxylated by adenosine deaminase to become biologically active 9-beta-D-arabinosylguanine (ara-G); ara-G incorporates into DNA, thereby inhibiting DNA synthesis and inducing an S phase-dependent apoptosis of tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0907349) 2-Amino-6-methoxypurine arabinoside;
2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine;
NELARABINE;
Nelarabine Intravenous Injection =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
|
- 1011. 2,4-Dichloro-1-(4-nitrophenoxy)benzene
- [A white, crystalline, solid, combustible, chlorinated compound. Nitrofen was used as an herbicide, but is no longer used or manufactured in the United States. Exposure to nitrofen irritates the skin, eyes and respiratory tract and affects the blood and central nervous system. This substance is teratogenic and carcinogenic in animals and is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0068833) =Organic Chemical; Hazardous or Poisonous Substance
| - 1061. 2-Amino-1,3-Dihydroxyoctadecane
- [A saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), L-threo-dihydrosphingosine competitively binds to the regulatory phorbol-binding domain of PKC, a kinase involved in tumorigenesis. This agent has been shown to act synergistically with other chemotherapeutic agents and may potentiate chemotherapy drug-induced apoptosis in vitro and in vivo. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41910&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41910&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1568" NCI Thesaurus) ( PDQ )] (UMLS (NCI) C0074987) =Lipid; Pharmacologic Substance ;
|
- 1012. 2,4-dihydroxy-5-methylpyrimidine
- [2,4-diketo-5-methylpyrimidine; one of the 5 major bases (with adenine, guanine, cytosine, and uracil) found in nucleic acids. ( CSP )] (UMLS (NCI) C0040087) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
=Pyrimidine;
nucleobase | - 1062. 2-Amino-1,7-dihydro-6H-purin-6-one
- [2-amino-6-hydroxypurine; one of the 5 major bases (with adenine, thymine, cytosine, and uracil) found in nucleic acids. ( CSP )] (UMLS (NCI) C0018321) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance =2-Aminopurine;
Hypoxanthines;
nucleobase;
=2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one |
- 1013. 2,4-Dioxo-5-fluoropyrimidine
- [pyrimidine analog that is an antineoplastic antimetabolite. ( CSP )] (UMLS (NCI) C0016360) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
[AN000] ANTINEOPLASTICS;
2, 4-Dioxopyrimidine;
fluoropyrimidine;
uracil analog;
[DE600] ANTINEOPLASTICS, TOPICAL =FLUOROURACIL 50 MG/ML;
FLUOROURACIL 5 %;
FLUOROURACIL 1 %;
FLUOROURACIL 2 %;
FLUOROURACIL 0.5 %;
| - 1063. 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
- [9-(2-hydroxyethoxymethyl) guanine; acts against herpesviruses by inhibiting the viral DNA polymerase. ( CSP )] (UMLS (NCI) C0001367) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
|
- 1014. 2,4-Imidazolidinedione, 5,5-diphenyl-3-((phosphonooxy)methyl)-, Disodium Salt
- [The sodium salt form of fosphenytoin, a prodrug that is hydrolyzed to the anticonvulsant phenytoin upon parental administration. Phenytoin exerts its effect most likely through an enhancement of sodium efflux from neurons in the motor cortex. This leads to a suppression of excessive neuronal firing and spread of seizure activity. Other physiologic effects from actions of phenytoin include modulation of the voltage-dependent calcium channels of neurons, inhibition of calcium flux across neuronal membranes and enhancement of sodium-potassium ATPase activity of neurons and glial cells. (NCI05) ( NCI )] (UMLS (NCI) C0284906) =Organic Chemical; Pharmacologic Substance =Fosphenytoin;
=FOSPHENYTOIN SODIUM 50 MG-PE/ML | - 1064. 2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one
- [9-(1,3-dihydroxy-2-propoxy)methylguanine; acyclovir analog which inhibits DNA replication of CMV and therefore has efficacy against AIDS-related oculopathy. ( CSP )] (UMLS (NCI) C0017066) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one;
[AM800] ANTIVIRALS;
2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one;
[OP203] ANTIVIRALS, TOPICAL OPHTHALMIC;
nucleoside analog;
=2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one;
DHPG sodium;
GANCICLOVIR 500 MG;
GANCICLOVIR 4.5 MG;
|
- 1015. 2,4-Oxazolidinedione, 3,5,5-trimethyl-
- [A dione-type anticonvulsant with antiepileptic activity. Trimethadione reduces T-type calcium currents in thalamic neurons, thereby stabilizing neuronal membranes, raising the threshold for repetitive activities in the thalamus and inhibiting corticothalamic transmission. This decreases the abnormal thalamocortical rhythmicity, which is thought to underlie the paroxysmal three-cycle-per-second spike-and-wave pattern seen with absence (petit mal) seizures. ( NCI )] (UMLS (NCI) C0041038) =Organic Chemical; Pharmacologic Substance ;
=[CN400] ANTICONVULSANTS;
oxazole =TRIMETHADIONE 150 MG;
TRIMETHADIONE 300 MG;
TRIMETHADIONE 40 MG/ML | - 1065. 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine
- [A synthetic, gray-white crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). It is one of the most abundant heterocyclic amines in a typical Western diet. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045811) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 1016. 2,4-Quinazolinediamine, 5-methyl-6-[[(3,4,5-trimethoxyphenyl)amino]methyl]-
- [2,4-diamino-5-methyl-6-(3,4,5-trimethoxy anilinomethyl)quinazoline; one of the most widely used cancer chemotherapeutic agents. ( CSP )] (UMLS (NCI) C0085176) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
quinazoline;
[AM900] ANTI-INFECTIVES, OTHER;
=TRIMETREXATE 25 MG | - 1066. 2-Amino-3,4-Dimethylimidazole[4,5-f]quinoline
- [A synthetic, yellow-green crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). 2-Amino-3-methylimidazo[4,5-f]quinoline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045819) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 1017. 2,6 dimethoxyphenylpenicillin
- [semisynthetic penicillin used as an antibacterial in resistant staphylococcal infections. ( CSP )] (UMLS (CSP) C0025643) =Organic Chemical; Antibiotic ;
=Penicillanic Acid;
[AM050] PENICILLINS;
[AM053] PENICILLINASE-RESISTANT PENICILLINS;
=4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-((2,6-dimethoxybenzoyl)amino)-3,3-dimethyl-7-oxo-, Monosodium Salt, Monohydrate,(2S-(2alpha,5alpha,6beta))- | - 1067. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline
- [A synthetic, pale orange to brown crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). It is one of the most abundant heterocyclic amines in a typical Western diet. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045822) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
|
- 1018. 2,6,10,14-Tetramethylpentadecane
- [A natural or synthetic isoprenoid hydrocarbon (C19) derivative, Pristane is commonly used in research to prime the abdomen prior to hybridoma implantation in experimental animals. An irritant that induces granulomatous inflammation and interferes with local lymphatic drainage, it increases ascitic yields. Pristane has a low margin of safety and is toxic at levels slightly higher than used to prime animals. (NCI04) ( NCI )] (UMLS (NCI) C0071986) =Organic Chemical; Pharmacologic Substance
| - 1068. 2-Amino-3-(5-hydroxy-1-H-indol-3-yl)propionic Acid
- [precursor of serotonin used as antiepileptic and antidepressant. ( CSP )] (UMLS (NCI) C0000578) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance
|
- 1019. 2,6-Bis(1,1-dimethylethyl)-4-methylphenol
- [2,6-di-tert-butyl-4-methylphonol, a perservative commonly used in packaged foods. ( CSP )] (UMLS (NCI) C0006507) =Organic Chemical; Pharmacologic Substance =Cresols;
food additive;
phenol;
Unclassified Ingredient Preparations =AQUA-A CREAM;
AQUADERM CREAM;
AQUADERM LOTION;
ALPHA KERI BAR SOAP;
KERI FACIAL SOAP;
BUTYLATED HYDROXYTOLUENE 100 GM | - 1069. 2-Amino-3-hydroxypropionic Acid
- [naturally occurring nonessential aminoacid, chemical name 2-amino-3-hydroxypropionic acid; it may be synthesized from glycine or threonine and is involved in the biosynthesis of purines, pyrimidines, and other amino acids. ( CSP )] (UMLS (NCI) C0036720) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance =Amino Acids, Neutral;
hydroxyaminoacid;
primary aminoacid;
Inactive Ingredient Preparations;
Unclassified Ingredient Preparations;
=(+)-4-Amino-3-isoxazolidinone;
SERINE 0.33 GM;
SERINE 0.5 GM;
SERINE 1.86 MG/ML;
SERINE 147 MG/100ML;
SERINE 150 MG/100ML;
SERINE 180 MG;
SERINE 2.21 MG/ML;
SERINE 2.25 MG/ML;
SERINE 2.65 MG/ML;
SERINE 20 MG;
SERINE 210 MG/100ML;
SERINE 230 MG/100ML;
SERINE 3 MG/ML;
SERINE 3.7 MG/ML;
SERINE 3.71 MG/ML;
SERINE 300 MG;
SERINE 347 MG/100ML;
SERINE 370 MG;
SERINE 4.5 MG/ML;
SERINE 4.95 MG/ML;
SERINE 420 MG/100ML;
SERINE 5 MG;
SERINE 5.3 MG/ML;
SERINE 5.92 MG/ML;
SERINE 500 MG;
SERINE 500 MG/100ML;
SERINE 56 MG/GM;
SERINE 590 MG/100ML;
SERINE 795 MG/100ML |
- 1020. 2,6-Diamino-3-(phenylazo)-pyridine Hydrochloride
- [A synthetic, brick-red crystalline solid that is only slightly soluble in cold water and ethanol but is soluble in boiling water, acetic acid, glycerol, ethylene glycol and propylene glycol. It is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include nausea, interference with the oxygen-carrying capacity of red blood cells (methemoglobinemia), hemolytic anemia as well as renal and hepatic toxicity. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0700555) =Organic Chemical; Pharmacologic Substance ;
=PHENAZOPYRIDINE;
=PHENAZOPYRIDINE HYDROCHLORIDE 100 MG;
PHENAZOPYRIDINE HYDROCHLORIDE 200 MG;
PHENAZOPYRIDINE HYDROCHLORIDE 50 MG;
PHENAZOPYRIDINE HYDROCHLORIDE 150 MG;
| - 1070. 2-Amino-3-methylimidazo[4,5-f]quinoline
- [A synthetic, light tan crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3-methylimidazo[4,5-f]quinoline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). 2-Amino-3-methylimidazo[4,5-f]quinoline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C1312059) 3-Methyl-3H-imidazo[4,5-f]quinolin-2-amine;
IQ =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance |
- 1021. 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-, Hydrochloride, (2R,6R,11R)-rel-
- [The hydrochloride salt form of pentazocine, a benzomorphan narcotic agonist-antagonist. Pentazocine hydrochloride binds to and activates kappa- and sigma-opioid receptors, resulting in sedation and analgesia. In addition, this agent antagonizes the mu-receptor. Pentazocine hydrochloride partially reverses opiate-induced cardiovascular, respiratory, and behavioral depression. ( NCI )] (UMLS (NCI) C0355587) =Organic Chemical; Pharmacologic Substance =PENTAZOCINE;
=PENTAZOCINE HYDROCHLORIDE 50 MG;
PENTAZOCINE HYDROCHLORIDE 12.5 MG;
PENTAZOCINE HYDROCHLORIDE 25 MG | - 1071. 2-Amino-4-(S-butylsulfonimidoyl) Butanoic Acid
- [used as a thiol depleter and inhibitor of the enzyme gamma glutamylcysteine synthase. ( CSP )] (UMLS (NCI) C0054252) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hazardous or Poisonous Substance =Amino Acids, Sulfur;
sulfhydryl reagent |
- 1022. 2-((2,3-Dimethylphenyl)amino)benzoic Acid
- [An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activity. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. ( NCI )] (UMLS (NCI) C0025152) =Organic Chemical; Pharmacologic Substance ;
=Anthranilic Acids;
[CN104] NONSTEROIDAL ANTI-INFLAMMATORY ANALGESICS =Mefenamate 250 MG | - 1072. 2-Amino-5-(carbamoylamino)pentanoic Acid
- [amino acid, C6H13N3O3, originally isolated from watermelon, that is produced as an intermediate in the conversion of ornithine to arginine during urea formation in the liver; chemical name L-ornithine, N5-(aminocarbonyl). ( CSP )] (UMLS (NCI) C0008864) =Amino Acid, Peptide, or Protein; Biologically Active Substance =aa;
|
- 1023. 2-((2,6-Dichlorophenyl)amino)-benzeneacetic Acid, Monopotassium Salt
- [The potassium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac potassium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. ( NCI )] (UMLS (NCI) C0282131) =Organic Chemical; Pharmacologic Substance ;
=2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid;
2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium Salt =DICLOFENAC POTASSIUM 50 MG | - 1073. 2-amino-5-bromo-6-phenyl-4-(3H)-pyrimidinone
- [An oral immunostimulant that causes the body to produce interferon and other substances. ( NCI )] (UMLS (NCI) C0054150) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 1024. 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium Chloride
- [slowly hydrolyzed cholinergic agonist that acts at both muscarinic and nicotinic receptors. ( CSP )] (UMLS (NCI) C0006945) =Organic Chemical; Pharmacologic Substance =choline;
cholinergic agent;
[OP102] MIOTICS, TOPICAL OPHTHALMIC;
[OP109] ANTIGLAUCOMA, OTHER =CARBACHOL 0.75 %WV;
CARBACHOL 1.5 %;
CARBACHOL 2.25 %;
CARBACHOL 3 %;
CARBACHOL 0.01 % | - 1074. 2-Amino-5-chlorotoluene
- [A yellowish to pinkish colored, synthetic leaflet material. p-Chloro-o-toluidine is used in industry in the manufacture of azo dyes and is used in the production of the pesticide chlordimeform. This substance is a possible mutagen and is reasonably anticipated to be a human carcinogen that may be associated with an increased risk of bladder cancer. (NCI05) ( NCI )] (UMLS (NCI) C0048164) =Organic Chemical; Pharmacologic Substance
|
- 1025. 2-((p-Bromo-alpha-phenylbenzyl)oxy)-N,N-dimethylethylamine Hydrochloride
- [The hydrochloride salt form of bromodiphenhydramine, a synthetic ethanolamine with histamine H1 antagonistic and sedative properties. Bromodiphenhydramine hydrochloride blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. This drug also prevents histamine-induced pain and itching of mucous membranes. ( NCI )] (UMLS (NCI) C0304299) =Organic Chemical; Pharmacologic Substance ;
=Bromazine;
=BROMODIPHENHYDRAMINE HYDROCHLORIDE 3.75 MG;
BROMODIPHENHYDRAMINE HYDROCHLORIDE 12.5 MG/5ML;
| - 1075. 2-Amino-6-(trifluoromethoxy)benzothiazole
- [A benzathiozole derivative with neuroprotective property. Although the mechanism of action has not been fully elucidated, riluzole may protect neural tissue by inhibiting glutamate release from presynaptic endings in the central nervous system. The agent also blocks postsynaptic NMDA-kainate-type glutamate receptors and inhibits voltage-dependent sodium channels. The inhibition of glutamatergic neurotransmission results in muscle relaxation and sedative effects. ( NCI )] (UMLS (NCI) C0073379) =Organic Chemical; Pharmacologic Substance ;
=thiazole;
[CN900] CNS MEDICATIONS, OTHER =RILUZOLE 50 MG |
- 1026. 2-(1-(Ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)pyridinium Phosphate
- [A class Ia antiarrhythmic agent with cardiac depressant properties. Disopyramide phosphate exerts its actions by blocking both sodium and potassium channels in cardiac membrane during phase 0 of the action potential. This slows the impulse conduction through the AV node and prolongs the duration of the action potential of normal cardiac cells in atrial and ventricular tissues. Disopyramide prolongs the QT interval and causes a widening of the QRS complex. It also posesses some anticholinergic and local anaesthetic properties. Disopyramide phosphate is used in the treatment of supraventricular tachycardia. ( NCI )] (UMLS (NCI) C0700534) =Organic Chemical; Pharmacologic Substance =disopyramide;
=DISOPYRAMIDE PHOSPHATE 100 MG;
DISOPYRAMIDE PHOSPHATE 150 MG;
| - 1076. 2-Amino-9,10-anthracenedione
- [A synthetic, red or orange-brown needle-shaped solid that is insoluble in water and soluble in alcohol, acetone, benzene and chloroform. It is used as intermediate for the synthesis of both anthraquinone dyes and pharmaceutical products. When 2-aminoanthraquinone is heated to decomposition, it emits toxic fumes of nitrogen oxides. The primary route of potential human exposure to this chemical is dermal contact. Acute exposure of humans to 2-aminoanthraquinone can cause irritation of the eyes and skin. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045870) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 1027. 2-(1-H-imidazol-4-yl) Ethylamine Dihydrochloride
- [A drug being studied for its ability to enhance the effectiveness of IL-2 in treating acute myeloid leukemia. ( NCI )] (UMLS (NCI) C0543456) =Organic Chemical; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine
| - 1077. 2-Aminonaphthalene
- [A synthetic, air-sensitive, colorless crystalline solid that is soluble in hot water, alcohol, ether and many organic solvents. Currently, it is only used in laboratory research. Because the commercial production and use of 2-naphthylamine are banned, the potential for human exposure is low. The general population may be exposed to this chemical through inhalation of emissions from sources where nitrogen-containing organic matter is burned, such as coal furnaces and cigarettes. At greatest risk of occupational exposure to 2-naphthylamine are laboratory technicians and scientists who use it in research. Acute inhalation exposure to high levels of 2-naphthylamine can result in methemoglobinemia, dyspnea, ataxia, hematuria, dysuria and hemorrhagic cystitis. It is known to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0000300) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 1028. 2-(1-Hexyloxyethyl)-2-Devinyl Pyropheophorbide-a
- [2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a. A drug that is used in photodynamic therapy that is absorbed by tumor cells; when exposed to light, it becomes active and kills the cancer cells. ( NCI )] (UMLS (NCI) C0248392) =Organic Chemical; Pharmacologic Substance ;
| - 1078. 2-Aminotoluene
- [A synthetic, light sensitive, light yellow liquid that is slightly soluble in water and miscible with carbon tetrachloride, diethyl ether and ethanol. The hydrochloride is a synthetic, light sensitive, white crystalline powder that is soluble in dimethylsulfoxide and ethanol. o-Toluidine and o-toluidine hydrochloride are used primarily as intermediates in the manufacture of dyes and pigments. When heated to decomposition, o-toluidine emits toxic fumes of nitrogen oxides while the hydrochloride also produces hydrochloric acid. Four studies of workers exposed to o-toluidine reported an excess of bladder cancers. o-Toluidine and o-toluidine hydrochloride are reasonably anticipated to be human carcinogens. (NCI05) ( NCI )] (UMLS (NCI) C0046584) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid
|
- 1029. 2-(1-Methylethyl)-4-pentenamide
- [An allylic compound that acts as a suicide inactivator of CYTOCHROME P450 by covalently binding to its heme moiety or surrounding protein. ( MSH )] (UMLS (NCI) C0002160) =Organic Chemical
| - 1079. 2-Aza-8-germaspiro[4.5]decane-2-propanamine, 8, 8-diethyl-N,N-dimethyl-, dihydrochloride
- (UMLS (NCI) C0954126) Spirogermanium HCl;
Spirogermanium hydrochloride =Organic Chemical; Pharmacologic Substance |
- 1030. 2-(2,3,5-Tri-O-acetyl-beta-D-ribofuranosyl)-as-triazine-3,5(2H,4H)-dione
- [A drug used in the treatment of psoriasis. ( NCI )] (UMLS (NCI) C0052757) =Organic Chemical; Pharmacologic Substance
| - 1080. 2-Aziridinecarboxamide, 1-[1-(2-cyano-1-aziridinyl)-1-methylethyl]
- [Azimexon (2-cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane) is a derivative of 2-cyanaziridine. Immunostimulant which shows therapeutic effects in tumor models and experimental infections in vitro, enhancing T lymphocyte transformation and phagocytosis. The mode of action of azimexon is unknown. It has been suggested that azimexon may alkylate DNA. In cancer patients it increases leukocytosis, blood active T rosettes, T4/T8 ratio, and is used as an adjuvant to chemotherapy in the treatment of melanoma and myeloma. ( NCI )] (UMLS (NCI) C0104835) =Organic Chemical; Pharmacologic Substance ;
|
- 1031. 2-(2-(Diethylamino)ethoxy)-3-phenylpropiophenone
- (UMLS (NCI) C0059677) =Organic Chemical; Pharmacologic Substance ;
| - 1081. 2-Benzimidazolinebutryric acid, 1-methyl-5-bis(2-chloroethyl)amino-, hydrochloride
- [The hydrochloride salt of bendamustine, a novel alkylating agent of the nitrogen mustard family with antitumor activity. Bendamustine, chemically related to the alkylator chlorambucil, has three active moieties: an alkylating group, in common with the nitrogen mustard family; a benzimidazole ring, which may act as a purine analog; and a butyric acid side-chain. This agent undergoes extensive first-pass metabolism by cytochrome p450 enzymes in vivo. One of the hydroxy metabolites, beta-hydroxybendamustine, alkylates and crosslinks macromolecules, thereby resulting in DNA, RNA and protein synthesis inhibition, and subsequently inducing apoptosis. ( NCI )] (UMLS (NCI) C0772139) Bendamustin Hydrochloride;
Bendamustine Hydrochloride =Organic Chemical; Pharmacologic Substance ;
|
- 1032. 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
- (UMLS (NCI) C0380453) =Organic Chemical; Pharmacologic Substance ;
| - 1082. 2-benzofurancarboximide,N-(2-((1-(chloromethyl)-1,6-dihydro-8-methyl-5-(((phenylamino)carbonyl0oxy0benzo(1,2-b:4,3-b')dipyrrol-3(2H0-yl)carbonyl-1H-indol-5-yl)-6-(diethylamino)-,(S)
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0172048) =Organic Chemical; Pharmacologic Substance ;
|
- 1033. 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) Acetamide
- (UMLS (NCI) C0382334) =Organic Chemical; Pharmacologic Substance ;
| - 1083. 2-bis[Cyclo(N-methyl-L-valyl-sarcosyl-L-prolyl-D-valyl-L-threonyl)]-1,9 dimethyl-4,6 3H-phenoxazinone-3
- [An anticancer drug that belongs to the family of drugs called antitumor antibiotics. ( NCI )] (UMLS (NCI) C0010934) =Amino Acid, Peptide, or Protein; Antibiotic =antineoplastic antibiotics;
Heterocyclic Compounds, 3-Ring;
cyclic peptide;
=DACTINOMYCIN 0.5 MG;
|
- 1034. 2-(2-Pyridyl)ethylidine-1,1-bisphosphonate
- [A synthetic pyridinyl bisphosphonate with anti-resorptive activity. Although the exact mechanism of action has yet to be fully elucidated, piridronic acid likely binds to hydroxyapatite crystals in the bone matrix and inhibits farnesyl pyrophosphate synthase, an enzyme that plays an important role in the mevalonate pathway. This inhibits the formation of isoprenoid metabolites that are substrates for protein prenylation. This prevents farnesylation and geranylgeranylation of proteins essential for osteoclast function, leading to the induction of apoptosis and eventually, osteoclast-cell death. By preventing osteoclast-mediated bone resorption, piridronic acid decreases bone turnover and stabilizes the bone matrix. ( NCI )] (UMLS (NCI) C0045686) =Organophosphorus Compound; Pharmacologic Substance ;
| - 1084. 2-Bromo-alpha-ergocryptine
- [D2 dopamine agonist used as a prolactin inhibitor. ( CSP )] (UMLS (NCI) C0006230) =Organic Chemical; Pharmacologic Substance ;
=[CN500] ANTIPARKINSON AGENTS;
ergoline;
Dopamine Agonist;
[AU900] AUTONOMIC AGENTS, OTHER =2-Bromo-alpha-ergocryptine Mesylate |
- 1035. 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
- [antioxidant flavonol widely distributed in plants. ( CSP )] (UMLS (NCI) C0034392) =Organic Chemical; Pharmacologic Substance; Vitamin =flavonoid;
vasoactive agent | - 1085. 2-Bromo-alpha-ergocryptine Mesylate
- [The mesylate salt form of bromocriptine, a semisynthetic, ergot alkaloid with antiparkinson and lactation inhibitory activity. Bromocriptine selectively binds to and activates the postsynaptic dopamine D2-like receptors in the corpus striatum of the central nervous system (CNS). D2-like receptors are coupled to inhibitory G-proteins, which inhibit adenylyl cyclase, thereby preventing signal transduction mediated via cAMP and leading to an inhibitory effect on neurotransmission. This improves Parkinson symptoms, such as dyskinesia. Bromocriptine also has an inhibitory effect on the anterior pituitary gland, which results in blockage of prolactin secretion, thereby suppressing lactation. ( NCI )] (UMLS (NCI) C0546852) =Organic Chemical; Pharmacologic Substance =2-Bromo-alpha-ergocryptine;
=BROMOCRIPTINE MESYLATE 2.5 MG;
BROMOCRIPTINE MESYLATE 5 MG |
- 1036. 2-(3,4-Dihydroxyphenyl)ethanol
- (UMLS (NCI) C0376776) =Organic Chemical; Pharmacologic Substance ;
| - 1086. 2-Butenoic acid, 3-bromo-4-(4-methoxyphenyl)-4-oxo-, sodium salt, (Z)- (9CI)
- (UMLS (NCI) C0893303) Acrylic acid, 3-p-anisoyl-3-bromo-, sodium salt;
Sodium Bromebrate;
Sodium cis-Beta-4-methoxybenzoyl-beta-bromacrylate =Organic Chemical; Pharmacologic Substance |
- 1037. 2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecanyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
- [family of isoprenoid quinones which serve as mitochondrial electron transport cofactors. ( CSP )] (UMLS (NCI) C0041536) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =Benzoquinone Compound;
cofactor | - 1087. 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol
- [antihypertensive agent; nonpeptide angiotension 1 subtype; angiotension 2 receptor antagonist/inhibitor. ( CSP )] (UMLS (NCI) C0126174) =Organic Chemical; Pharmacologic Substance ;
=antihypertensive agent;
biphenyl compound;
imidazole;
Tetrazoles;
[CV805] ANGIOTENSIN II INHIBITORS;
=2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, Monopotassium Salt;
LOSARTAN 25 MG;
LOSARTAN 50 MG |
- 1038. 2-(3-ethylureido)-6-methylpyridine
- (UMLS (NCI) C0532706) =Organic Chemical; Pharmacologic Substance
| - 1088. 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, Monopotassium Salt
- [The potassium salt form of losartan, a non-peptide angiotensin II antagonist with antihypertensive activity. Losartan potassium selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor. Angiotensin II, formed from angiotensin I by angiotensin-converting enzyme (ACE), stimulates the adrenal cortex to synthesize and secrete aldosterone, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. Losartan potassium, by blocking the binding of angiotensin II to the AT 1 receptor, promotes vasodilatation and decreases the effects of aldosterone. ( NCI )] (UMLS (NCI) C0700492) =Organic Chemical; Pharmacologic Substance ;
=2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol;
=LOSARTAN POTASSIUM 25 MG;
LOSARTAN POTASSIUM 50 MG;
LOSARTAN POTASSIUM 100 MG;
|
- 1039. 2-(4-(((3,5-Dimethylanilino)Carbonyl)Methyl)Phenoxy)-2-Methylpropionic Acid
- [A synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. (NCI04) ( NCI )] (UMLS (NCI) C0080719) =Organic Chemical; Pharmacologic Substance
| - 1089. 2-CdA/CLB
- (UMLS (NCI) C0281307) =Therapeutic or Preventive Procedure ;
|
- 1040. 2-(4-Bromophenyl)-4H-1-benzopyran-4-one
- (UMLS (NCI) C0763460) 2-(4-Bromophenyl)chromen-4-one;
4'-Bromoflavone;
4-Bromoflavone =Organic Chemical; Pharmacologic Substance | - 1090. 2-CdA/CTX/PRED
- (UMLS (NCI) C0678010) =Therapeutic or Preventive Procedure
|
- 1041. 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester
- [fibric acid derivative used in the treatment of hyperlipoproteinemia and hypertriglyceridemia. ( CSP )] (UMLS (NCI) C0009002) =Organic Chemical; Pharmacologic Substance ;
=[CV350] ANTILIPEMIC AGENTS;
butyrate;
Clofibric Acid;
chlorophenoxyacetate | - 1091. 2-CdA/IDA
- (UMLS (NCI) C0677832) =Therapeutic or Preventive Procedure ;
|
- 1042. 2-(Acetyloxy)benzoic Acid
- [prototypical analgesic used in the treatment of mild to moderate pain; has antiinflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins; aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. ( CSP )] (UMLS (NCI) C0004057) =Organic Chemical; Pharmacologic Substance
| - 1092. 2-CdA/VP-16
- (UMLS (NCI) C0392926) =Therapeutic or Preventive Procedure ;
|
- 1043. 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide Monohydrochloride
- [The hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability. ( NCI )] (UMLS (NCI) C0546869) =Organic Chemical; Pharmacologic Substance =[CV300] ANTIARRHYTHMICS;
.omega.-Diethylamino-2,6-dimethylacetanilide;
[CN204] LOCAL ANESTHETICS, INJECTION;
[GU900] GENITOURINARY AGENTS, OTHER =LIDOCAINE HCL MISC. POWDER (GM);
LIDOCAINE HYDROCHLORIDE 1 %;
LIDOCAINE HYDROCHLORIDE 1 %WV;
LIDOCAINE HYDROCHLORIDE 100 MG/ML;
LIDOCAINE HYDROCHLORIDE 160 MG;
LIDOCAINE HYDROCHLORIDE 2.5 %;
LIDOCAINE HYDROCHLORIDE 300 MG;
LIDOCAINE HYDROCHLORIDE 4 %;
LIDOCAINE HYDROCHLORIDE 10 MG/ML;
LIDOCAINE HYDROCHLORIDE 0.5 %;
LIDOCAINE HYDROCHLORIDE 5 %;
LIDOCAINE HYDROCHLORIDE 1 GM;
LIDOCAINE HYDROCHLORIDE 200 MG/ML;
LIDOCAINE HYDROCHLORIDE 2 GM;
LIDOCAINE HYDROCHLORIDE 2 MG/ML;
LIDOCAINE HYDROCHLORIDE 4 MG/ML;
LIDOCAINE HYDROCHLORIDE 20 MG/ML;
LIDOCAINE HYDROCHLORIDE 1.5 %;
LIDOCAINE HYDROCHLORIDE 40 MG/ML;
LIDOCAINE HYDROCHLORIDE 8 MG/ML;
LIDOCAINE HYDROCHLORIDE 2 %;
| - 1093. 2-Chlorallyl Diethyldithiocarbamate
- [A synthetic, amber oil that is slightly soluble in water and soluble in most organic solvents. Sulfallate products are no longer used in the United States. Therefore, the potential for human exposure is low. When heated to decomposition, sulfallate emits toxic fumes of hydrochloric acid, nitrogen, and sulfur oxides. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0054976) =Organic Chemical; Pharmacologic Substance ;
|
- 1044. 2-(DIETHYLAMINO)ETHANOL
- (UMLS (NCI) C0046079) =Organic Chemical; Pharmacologic Substance ;
| - 1094. 2-Chloro-1,3-butadiene
- [A colorless, flammable, carcinogenic, chlorinated hydrocarbon with a pungent, ethereal odor. Chloroprene is used as a chemical intermediate in the manufacture of neoprene rubber. Exposure to this substance causes damage to the skin, lungs, CNS, kidneys, liver and depression of the immune system. Chloroprene is a mutagen and carcinogen in animals and is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0008267) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 1045. 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate Monohydrochloride
- [The hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation. ( NCI )] (UMLS (NCI) C0740235) Benzoic Acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl Ester, Hydrochloride;
Proparacaine Hydrochloride;
PROPARACAINE HYDROCHLORIDE PREPARATION =Organic Chemical; Pharmacologic Substance =Proparacaine;
=PROPARACAINE HYDROCHLORIDE 0.5 % | - 1095. 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
- [extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. ( CSP )] (UMLS (NCI) C0014277) =Organic Chemical; Pharmacologic Substance ;
=[CN200] ANESTHETICS;
Methyl Ethers;
[CN201] ANESTHETICS INHALATION;
haloether =ENFLURANE 99.9 % |
- 1046. 2-(Diethylamino)ethyl p-aminobenzoate Monohydrochloride
- [The hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation. ( NCI )] (UMLS (NCI) C0358490) =Organic Chemical; Pharmacologic Substance =PROCAINE;
=PROCAINE HYDROCHLORIDE 1 %;
PROCAINE HYDROCHLORIDE 2 %;
PROCAINE HYDROCHLORIDE 1.25 %;
PROCAINE HYDROCHLORIDE 10 %;
| - 1096. 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine
- [phenothiazine derivative used chiefly as an antiemetic. ( CSP )] (UMLS (NCI) C0033229) =Organic Chemical; Pharmacologic Substance =[GA700] ANTIEMETICS;
Phenothiazine;
[CN700] ANTIPSYCHOTICS;
=2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine Edisylate;
Prochlorperazine Dimaleate;
2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine Edisylate;
Prochlorperazine Dimaleate;
PROCHLORPERAZINE 10 MG;
PROCHLORPERAZINE 2.5 MG;
PROCHLORPERAZINE 25 MG;
PROCHLORPERAZINE 5 MG/ML;
PROCHLORPERAZINE 5 MG |
- 1047. 2-(Difluoromethyl)-DL-ornithine
- [polyamine antagonist which reversibly inhibits DNA polymerase and irreversibly inhibits ornithine decarboxylase; used against bladder cancer, with potential applications in epilepsy and PCP withdrawal. ( CSP )] (UMLS (NCI) C0086156) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Antiprotozoal Agent;
fluoroaminoacid;
| - 1097. 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine Edisylate
- [The edisylate salt form of prochlorperazine, a derivative of phenothiazine with antipsychotic and antiemetic properties. Prochlorperazine edisylate blocks postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, including hallucinations and delusions. Prochlorperazine edisylate appears to exert its antiemetic activity by blocking the dopamine and histamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting. ( NCI )] (UMLS (NCI) C0033230) =Organic Chemical; Pharmacologic Substance =2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine;
=PROCHLORPERAZINE EDISYLATE 5 MG/ML;
PROCHLORPERAZINE EDISYLATE 5 MG/5ML;
|
- 1048. 2-(Difluoromethyl)-dl-ornithine Hydrochloride, Monohydrate
- [The hydrochloride form of eflornithine, a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. (NCI04) ( NCI )] (UMLS (NCI) C0282042) =Amino Acid, Peptide, or Protein; Pharmacologic Substance =Alpha-Difluoromethylornithine;
=EFLORNITHINE HYDROCHLORIDE 13.9 % | - 1098. 2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine
- [prototypical phenothiazine antipsychotic drug; antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors; chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup. ( CSP )] (UMLS (NCI) C0008286) =Organic Chemical; Pharmacologic Substance ;
=Phenothiazine;
[CN700] ANTIPSYCHOTICS;
[CN701] PHENOTHIAZINES/RELATED, ANTIPSYCHOTICS;
=2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine Monohydrochloride;
CHLORPROMAZINE 100 MG;
CHLORPROMAZINE 25 MG |
- 1049. 2-(Methacryloyloxy)ethanol
- [A hydroxyester compound and a resin monomer used in desensitizing dentin. By applying 2-hydroxyethyl methacrylate locally to sensitive teeth, sensitive areas in the teeth get sealed and block the dentinal tubules at the dentin surface from stimuli that cause pain. This prevents excitation of the tooth nerve and relieves pain caused by tooth hypersensitivity. ( NCI )] (UMLS (NCI) C0063127) =Organic Chemical; Biomedical or Dental Material ;
| - 1099. 2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine Monohydrochloride
- [The hydrochloride salt form of chlorpromazine, a phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine hydrochloride exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, such as hallucinations and delusions. Chlorpromazine hydrochloride appears to exert its anti-emetic activity by blocking the dopamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting. ( NCI )] (UMLS (NCI) C0355077) =Organic Chemical; Pharmacologic Substance =2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine;
=CHLORPROMAZINE HYDROCHLORIDE 25 MG;
CHLORPROMAZINE HYDROCHLORIDE 100 MG;
CHLORPROMAZINE HYDROCHLORIDE 10 MG;
CHLORPROMAZINE HYDROCHLORIDE 10 MG/5ML;
CHLORPROMAZINE HYDROCHLORIDE 150 MG;
CHLORPROMAZINE HYDROCHLORIDE 200 MG;
CHLORPROMAZINE HYDROCHLORIDE 30 MG;
CHLORPROMAZINE HYDROCHLORIDE 30 MG/ML;
CHLORPROMAZINE HYDROCHLORIDE 75 MG;
CHLORPROMAZINE HYDROCHLORIDE 50 MG;
CHLORPROMAZINE HYDROCHLORIDE 100 MG/ML;
CHLORPROMAZINE HYDROCHLORIDE 25 MG/ML;
|
- 1050. 2-(Methoxycarbonyl)propene
- [A methyl ester of methacrylic acid. Methyl methacrylate is a reactive resin, and the polymerized form is used as cement in dentistry, orthopaedic surgery and ophthalmology. The monomer form of this agent has relaxation effect on smooth muscle systemically, which might be a result of nitric oxide-mediated response. ( NCI )] (UMLS (NCI) C0066409) =Organic Chemical; Biomedical or Dental Material ;
=Methylmethacrylates;
[XX000] MISCELLANEOUS AGENTS;
Inactive Ingredient Preparations;
=METHYL METHACRYLATE 100 % | - 1100. 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine Succinate(1:1)
- [The succinate salt form of loxapine, a tricyclic dibenzoxazepine antipsychotic agent with antiemetic, sedative, anticholinergic, and antiadrenergic actions. Loxapine succinate exerts its actions by blocking the dopamine receptors at postsynaptic receptor sites in the limbic system, cortical system and basal ganglia, thereby reducing the hallucinations and delusions that are associated with schizophrenia. This agent also exerts extrapyramidal side effects. ( NCI )] (UMLS (NCI) C0024057) =Organic Chemical; Pharmacologic Substance ;
=LOXAPINE;
=LOXAPINE SUCCINATE 10 MG;
LOXAPINE SUCCINATE 25 MG;
LOXAPINE SUCCINATE 50 MG;
LOXAPINE SUCCINATE 5 MG;
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