I I- I0 I1 I2 I3 I4 I5 I6 I7 I8 I9 IA IB IC ID IE IF IG IH II IK IL IM IN IO IP IQ IR IS IT IU IV IX
131I-HuCC49-deltaCH2
[A radioimmunoconjugate consisting of the humanized monoclonal antibody (MoAb) CC49 having CH2 domain deleted, labeled with iodine 131 (I-131). MoAb CC49-deltaCH2 recognizes an epitope of the tumor-associated glycoprotein (TAG) 72 that is expressed by a wide range of cancers, including colorectal, gastric, pancreatic, ovarian, endometrial, breast, non-small cell lung, and prostate cancers. I-131 MoAb CC49-delta CH2 delivers beta and gamma radiation emitting I-131 nuclide directly to tumor cells that express TAG-72, thereby allowing imaging and/or treatment of cancers. ( NCI )]
UMLS (NCI) C1134477131I-MOAB CC49-deltaCH2
I131 MOAB CC49-deltaCH2
Iodine I 131 Monoclonal Antibody CC49-deltaCH2
I131 MOAB CC49-deltaCH2
Iodine I 131 Monoclonal Antibody CC49-deltaCH2
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor
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