[Encoded by human ALOX15 Gene, a putative mutator gene regulated by tumor-suppressor TP53, 661-amino acid 74.7 kD cytoplasmic Arachidonate 15-Lipoxygenase (Lipoxygenase Family) acts in leukotriene biosynthesis and is implicated in anti-inflammation, membrane remodeling, and cancer development or metastasis. It converts arachidonic acid to 15s-hydroperoxyeicosatetraenoic acid. (OMIM, Swiss-Prot, and NCI) ( NCI )]
UMLS (NCI) C0003692 - Amino Acid, Peptide, or Protein
- Enzyme