[An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA. ( MSH )]
UMLS (CSP) C0011519 - Amino Acid, Peptide, or Protein
- Enzyme
Relation/PAR: endodeoxyribonuclease
Relation/CHD: dornase alfa