- 1. Deubiquitinating
- [The generation of ubiquitin from proproteins and the processing of polyubiquitin chains to release monomeric ubiquitin. (NCI) ( NCI )] (UMLS (NCI) C1157996) Deubiquitination =Molecular Function
| - 6. deuterium
- [stable isotope of hydrogen; has one neutron and one proton in the nucleus. ( CSP )] (UMLS (CSP) C0011744) =Element, Ion, or Isotope =H element;
stable isotope |
- 2. Deubiquitinating Enzyme
- [Deubiquitinating Enzymes are hydrolases that catalyze cleavage of ubiquitinated substrates with addition of H2O at the point of cleavage. Protein ubiquitination regulates the half-lives of many proteins by targeting them for degradation. Ubiquitination and deubiquitination enzymes participate in highly regulated protein degradation, chromatin remodeling, heat shock, cell cycle progression, differentiation, antigen presentation, apoptosis, signal transduction, transcriptional activation, biological clocks, receptor down regulation, and endocytosis. ( NCI )] (UMLS (NCI) C1333282) =Amino Acid, Peptide, or Protein; Enzyme
| - 7. deuterium oxide
- [isotopic compound of hydrogen of mass 2 (deuterium) with oxygen; used to study mechanisms and rates of chemical or nuclear reactions, as well as biological processes. ( CSP )] (UMLS (CSP) C0011745) =Inorganic Chemical =WATER;
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- 3. Deubiquitinating Enzyme 6
- [Encoded by human TRE2 Gene, some evidence suggests that human Ubiquitin Specific Protease 6 (C19 Peptidase Family) may actually be encoded by separate elements on chromosomes 5, 18, and 17. The 1089-amino acid 122 kD hydrophilic protein contains two charge clusters, suggesting nucleic acid-binding properties. Ubiquitin Specific Protease 6 appears to have ATP-independent isopeptidase activity, cleaving at the carboxyl terminus of ubiquitin. (OMIM, Swiss-Prot, LocusLink, and NCI) ( NCI )] (UMLS (NCI) C1175888) Ubiquitin Carboxyl-Terminal Hydrolase 6;
Ubiquitin Specific Protease 6; Ubiquitin Thiolesterase 6; Ubiquitin-Specific Processing Protease 6; USP6 =Amino Acid, Peptide, or Protein; Enzyme | - 8. Deuteromycetes
- [large and heterogenous group of fungi whose common characteristic is the absence of a sexual state; many of the pathogenic fungi in humans belong to this group. ( CSP )] (UMLS (CSP) C0011746) =Fungus =Fungi;
=Moniliales |
- 4. Deubiquitinating Enzyme 8
- [Encoded by human USP8 Gene (C19 Peptidase Family), Ubiquitin Specific Protease 8 is a deubiquitinating enzyme related to the TRE2 oncogene product that cleaves at the carboxyl terminus of ubiquitin. In chronic myeloproliferative disorder, an oncogenic fusion of p85-beta occurs with the carboxyl end of USP8. (OMIM, Swiss-Prot, LocusLink, and NCI) ( NCI )] (UMLS (NCI) C0663052) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 9. deuteron
- [ ] (UMLS (CSP) C0205733) =Element, Ion, or Isotope
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- 5. DEUTAN DEFECT
- [ ] (UMLS (ICD9CM) C0155016) =Disease or Syndrome
| - 10. Deutsche Mark
- [Deutsche Mark, monetary currency of Germany ( HL7V3.0 )] (UMLS (HL7) C1555426) =Quantitative Concept =Currency;
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