- 1. D(1B) Dopamine Receptor
- [Dopamine Receptor D5, encoded by the human DRD5 gene, is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. This receptor complexes selectively with GABA-A ligand-gated channel through the direct binding of its carboxy-terminal domain with the second intracellular loop of the GABA-A gamma-2 (short) receptor subunit. This physical association enables mutual inhibitory functional interactions between these receptor systems. Pseudogenes related to this gene reside on chromosomes 1 and 2. Defects in DRD5 are a cause of blepharospasm, a primary focal dystonia affecting the orbicularis oculi muscles, usually beginning in middle age. (From LocusLink, Swiss-Prot, OMIM and NCI) ( NCI )] (UMLS (NCI) C0114836) =Amino Acid, Peptide, or Protein; Receptor ;
| - 7. DBD/DOX
- (UMLS (NCI) C0278921) =Therapeutic or Preventive Procedure
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- 2. DB-67
- (UMLS (NCI) C0961890) Silatecan DB-67 =Organic Chemical; Pharmacologic Substance
| - 8. DBF4
- [This gene is involved in DNA replication, protein binding and cell cycle control. ( NCI )] (UMLS (NCI) C1332118) DBF4 Gene;
DBF4 Homolog (S. cerevisiae) wt Allele =Gene or Genome ;
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- 3. DBA
- (UMLS (NCI) C0025923) =Mammal ;
| - 9. DBH (dopamine beta hydroxylase)
- [ ] (UMLS (CSP) C0013032) =Amino Acid, Peptide, or Protein; Enzyme ;
=Oxygenase;
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- 4. DBC1
- [Encoded by human tumor suppressor DBCCR1 Gene, 761-amino acid 88.9-kD DBCCR1 Protein contains a MAC/Perforin domain, seven potential N-glycosylation sites, four N-myristoylation sites, and thirty phosphorylation sites. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0675026) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 10. DBL
- [This gene is involved in signal transduction. ( NCI )] (UMLS (NCI) C0812211) Diffuse B-Cell Lymphoma Oncogene;
MCF.2 Cell Line Derived Transforming Sequence;
MCF2;
MCF2 Cell Line Derived Transforming Sequence Gene;
MCF2 Gene;
Oncogene DBL;
Oncogene MCF2;
Oncogene, DBL;
Oncogene, MCF-2 =Gene or Genome |
- 5. DBC1
- [This gene plays a role in receptor-mediated signal transduction. ( NCI )] (UMLS (NCI) C1413915) DBC1 Gene;
Deleted in Bladder Cancer 1 Gene =Gene or Genome | - 11. DBL Oncoprotein
- [Human DBL Oncoprotein is product of a mutated variant (Oncogene DBL) of widely expressed MCF2 Gene, which encodes 4 alternative variants of 66-kDa MCF2 (DBL) p66 Protein, a cytoplasmic and membrane phosphoserine guanine nucleotide exchange factor that modulates the activity of small RHO GTPases by promoting conversion from GDP- to GTP-bound form. p66 contains a CRAL-TRIO domain, a DH domain, a PH domain and a spectrin repeat; the DH domain catalyzes GDP-GTP exchange. Activated DBL oncogene is generated by 5-prime recombination with 3 (pter-p21) and by 3-prime recombination with 16 (p13-q22). The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42. DBL Oncoprotein disrupts normal cell function. ( NCI )] (UMLS (NCI) C0069500) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 6. DBD/5-FU/MTX/PRED
- (UMLS (NCI) C0279356) =Therapeutic or Preventive Procedure
| - 12. DBS
- [A highly invasive form of electroanalgesia mainly used in the management of debilitating chronic pain syndromes after all other less invasive therapeutic modalities (including SCS) have failed. (White, Li, and Chiu) ( NCI )] (UMLS (NCI) C0394162) =Therapeutic or Preventive Procedure
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