- 1. D-Phenylalanine
- [The synthetic dextro isomer of phenylalanine, an essential amino acid with anti-depressant and analgesic activity. D-Phenylalanine is converted into tyrosine and tyrosine in turn is converted into L-dopa, norepinephrine, and epinephrine, three key neurotransmitters. As a result this agent is associated with elevated levels of the neurotransmitters dopamine and norepinephrine in the brain, which may alleviate symptoms of depression. In addition, as an inhibitor of enkephalinase, which metabolizes endorphins, D-phenylalanine may be used to treat chronic pain through blocking the break down of endorphins (natural pain killers). ( NCI )] (UMLS (NCI) C0771172) PHENYLALANINE,D-;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance | - 3. DPN hydrolase
- [An enzyme that catalyzes the hydrolysis of nicotinamide adenine dinucleotide (NAD) to NICOTINAMIDE and ADENOSINE DIPHOSPHATE RIBOSE. Some are extracellular (ectoenzymes).The enzyme from some sources also catalyses the hydrolysis of nicotinamide adenine dinucleotide phosphate (NADP). ( MSH )] (UMLS (CSP) C0027277) =Amino Acid, Peptide, or Protein; Enzyme ;
=N glycosidase;
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- 2. DPC4 Protein
- [The SMAD4 tumor suppressor protein specifically recognizes an eight base pair palindromic DNA sequence and is critical for transmitting TGFB, and related cytokine signals, to the cell nucleus to mediate transcriptional activation of target genes. The MADH4 gene is a cloned gene for Juvenile Polyposis, associated with colon cancer. (from OMIM 600993 and NCI) ( NCI )] (UMLS (NCI) C0385939) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 4. DPPE
- [Belongs to a group of antihormone drugs. ( NCI )] (UMLS (NCI) C0915182) Tesmilifene Hydrochloride;
=Organic Chemical; Pharmacologic Substance ;
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