- 1. DJ
- [A country in Eastern Africa, bordering the Gulf of Aden and the Red Sea, between Eritrea and Somalia. (NCI) ( NCI )] (UMLS (NCI) C0012836) =Geographic Area ;
| - 2. DJ-927
- [A semi-synthetic orally-available taxane derivative with potent antineoplastic properties. DJ-927 binds to tubulin, promoting microtubule assembly and stabilization and preventing microtubule depolymerization, thereby inhibiting cell proliferation. As it represents a poor substrate for P-glycoprotein-related drug resistance mechanisms, this agent may be useful for treating multi-drug resistant tumors. DJ-927I is more potent than paclitaxel and docetaxel and is the first oral taxane derivative. (NCI04) ( NCI )] (UMLS (NCI) C1313820) =Organic Chemical; Pharmacologic Substance ;
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