[Diphtheria Toxin Receptor, encoded by the human DTR gene, is a heparin-binding EGF-like growth factor. It is mitogenic for fibroblasts and smooth muscle and may be involved in macrophage-mediated cellular proliferation. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. This mature type I membrane protein is released into the extracellular space and probably binds to a receptor. (From LocusLink, Swiss-Prot and NCI) ( NCI )]
UMLS (NCI) C0058402 - Amino Acid, Peptide, or Protein
- Immunologic Factor
- Receptor
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