[Encoded by human SAT Gene, 171-aa 20-kDa cytoplasmic Spermidine/Spermine N1-Acetyltransferase is a highly regulated homotetrameric rate-limiting enzyme in the catabolic polyamine metabolism pathway that regulates intracellular polyamine concentration and polyamine transport out of cells. SAT acts on putrescine, spermidine, spermine, N(1)-, and N(8)-acetylspermidine and catalyzes N(1)-acetylation of spermidine and spermine. (NCI) ( NCI )]
UMLS (NCI) C0072632 - Amino Acid, Peptide, or Protein
- Enzyme