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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
D D D- D0 D1 D2 D5 D7 D8 D9 DA DB DC DD DE DF DG DH DI DJ DK DL DM DN DO DP DR DS DT DU DV DW DX DY
DN- DNA DNE

DNA Mismatch Repair Gene Homolog

[Associated with colon, endometrial, and stomach cancers, DNA Mismatch Repair Protein PMS2, a 97-kD protein encoded by the ubiquitously expressed PMS2 Gene (MUTL/HEXB family) is involved with MSH2 and MLH1 in mismatch repair of dinucleotide and trinucleotide sequences. PMS2 is part of the BASC genome surveillance complex. MSH2 and MLH1 interact with PMS1, PMS2, and MSH6. Essential for repair of replication slippage errors, PMS2 is a cloned gene for Turcot syndrome and Hereditary Non-Polyposis Colon Cancer. Transcribed from the opposite strand, JTV1 overlaps PMS2. (From SWISS-PROT, OMIM, and NCI) ( NCI )]
UMLS (NCI) C1333235
DNA Mismatch Repair Protein PMS2
PMS2
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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