[An ester prodrug of epinephrine, with sympathomimetic activity. Due to its lipophilicity, dipivefrin penetrates more easily to the anterior chamber of the eye and is hydrolyzed to epinephrine, when applied locally. Epinephrine, an adrenergic agonist, enhances the outflow of aqueous humor and decreases the production of aqueous humor by vasoconstriction. The overall result is a reduction in intraocular pressure. ( NCI )]
UMLS (NCI) C0058415 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: Adrenal
[OP103] ADRENERGICS, TOPICAL OPHTHALMIC
Relation/CHD: (1)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene Dipivalate Hydrochloride