[The sodium salt form of phenytoin, a hydantoin derivate and non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin sodium promotes sodium efflux from neurons located in the motor cortex, thereby stabilizing the neuron and inhibiting synaptic transmission. This leads to a reduction in posttetanic potentiation at synapses, an inhibition of repetitive firing of action potentials and ultimately inhibits the spread of seizure activity. ( NCI )]
UMLS (NCI) C0237417 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: 5,5-Diphenyl-2,4-imidazolidinedione
Relation/CHD: PHENYTOIN SODIUM 100 MG
PHENYTOIN SODIUM 125 MG/5ML
PHENYTOIN SODIUM 50 MG/ML
PHENYTOIN SODIUM 30 MG
PHENYTOIN SODIUM 300 MG
PHENYTOIN SODIUM 200 MG