[An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activity. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. ( NCI )]
UMLS (NCI) C0025152 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: Anthranilic Acids
[CN104] NONSTEROIDAL ANTI-INFLAMMATORY ANALGESICS
Relation/CHD: Mefenamate 250 MG