- 7701. Anterior Spinal Artery
- (UMLS (NCI) C0149603) =Body Part, Organ, or Organ Component
| - 7751. anthrax edema factor
- [ ] (UMLS (CSP) C0962680) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 7702. Anterior staphyloma, localized
- [ ] (UMLS (ICD9CM) C0155362) =Disease or Syndrome ;
| - 7752. anthrax lethal factor
- [ ] (UMLS (CSP) C0964849) =Amino Acid, Peptide, or Protein; Biologically Active Substance; Hazardous or Poisonous Substance
|
- 7703. Anterior Supratentorial Cistern
- (UMLS (NCI) C1510913) Parasellar Cistern;
=Body Part, Organ, or Organ Component ;
| - 7753. anthrax protective antigen
- [ ] (UMLS (CSP) C0134992) =Amino Acid, Peptide, or Protein; Biologically Active Substance; Hazardous or Poisonous Substance
|
- 7704. Anterior Surface of the Epiglottis
- (UMLS (NCI) C0227160) =Body Location or Region
| - 7754. ANTHRAX SEPTICEMIA
- [ ] (UMLS (ICD9CM) C0152946) =Disease or Syndrome
|
- 7705. Anterior Surface of the Kidney
- (UMLS (NCI) C0227609) =Body Location or Region
| - 7755. anthrax toxin
- [toxic substances formed in or elaborated by Bacillus anthracis; consists of 3 separate proteins; protective antigen or factor (pa), edema factor (ef) and lethal factor (lf). ( CSP )] (UMLS (CSP) C0051962) =Amino Acid, Peptide, or Protein; Biologically Active Substance; Hazardous or Poisonous Substance =bacterial toxin;
|
- 7706. Anterior Surface of the Lens
- (UMLS (NCI) C0229227) =Body Location or Region
| - 7756. Anthrax Toxin Mechanism of Action
- [One of the key causes of anthrax virulence is the action of three specific factors produced by the bacterium Bacillus anthracis. Even with successful antibiotic treatment, anthrax toxins can remain in the circulation and cause lethality. The toxins produced by anthrax bacteria are lethal factor (LF), protective antigen (PA) and edema factor (EF). The entry of toxin into cells begins with the recognition of a cellular receptor in the plasma membrane by PA. Proteolytic cleavage of cell-bound PA creates a smaller fragment that then multimerizes into a pore-like structure in the plasma membrane. The LF and EF proteins bind to the PA pre-pore, followed by internalization of the entire structure through receptor-mediated endocytosis. In the endosomal compartment, the acidic pH causes a conformational change that inserts PA fragments and releases LF and EF into the cytoplasm. In the cytoplasm, LF acts as a protease that cleaves MAP kinase kinase (MAPKK 1 and MAPKK 2), inhibiting pathways that rely on this kinase family and causing cell death. Edema factor is an adenylate cyclase that inhibits the immune response, including phagocytosis by macrophages. (BioCarta) ( NCI )] (UMLS (NCI) C1510921) Anthrax Toxin Pathway;
=Molecular Function ;
|
- 7707. Anterior Surface of the Liver
- (UMLS (NCI) C0458924) =Body Location or Region
| - 7757. Anthropoidea
- [suborder of primates including monkeys, anthropoid apes and man; have flattened digits or cupped nails, true hands, man-like appearance; can be tailed or tailless. ( CSP )] (UMLS (CSP) C1564897) =Mammal; ;
=Mammals, Primates;
=Cercopithecidae;
great ape;
Ceboidea |
- 7708. Anterior Surface of the Prostate
- (UMLS (NCI) C0227960) =Body Location or Region
| - 7758. anthropology
- [The branch of science concerned with origin and development of humans in all their physical, social, and cultural relationships. ( NCI )] (UMLS (CSP) C0003184) =Occupation or Discipline ;
|
- 7709. Anterior Surface of the Stomach
- (UMLS (NCI) C0733984) =Body Location or Region
| - 7759. anthropometry
- [measurement of the physical dimensions of the human or other primate body characteristics such as size, breadth, girth, weight, proportion and distance between anatomical points; also includes segment masses, the centers of gravity of body segments, and the ranges of joint motion, which are used in biomechanical analyses of work postures; in anthropology it is used to refer to different body sizes and proportions of individuals belonging to different populations. ( CSP )] (UMLS (CSP) C0003188) =Research Activity ;
|
- 7710. Anterior Surface of the Vagina
- (UMLS (NCI) C1510914) =Body Location or Region ;
| - 7760. Anti B4bR
- [An immunotoxin comprised of an anti-B4 (CD19) murine monoclonal antibody linked to the modified plant-derived toxin blocked ricin. The antibody portion of anti-B4 blocked ricin immunotoxin binds to B lymphocytes that express CD19; the ricin portion cleaves the N-glycosidic bond between the ribose and adenine base at position 4324 in the B lymphocyte 28S ribosomal RNA, resulting in ribosome inactivation, inhibition of protein synthesis, and cell death. (NCI04) ( NCI )] (UMLS (NCI) C0763109) Anti B4-BR;
Anti-B4 Blocked Ricin;
Anti-B4 Blocked Ricin Immunotoxin;
Anti-B4-bR;
Monoclonal Antibody Anti-B4 Blocked Ricin =Pharmacologic Substance; Immunologic Factor |
- 7711. ANTERIOR SYNECHIAE
- (UMLS (ICD9CM) C0152252) =Disease or Syndrome ;
| - 7761. Anti CD3
- [A humanized monoclonal antibody deficient in Fc receptor binding directed against CD3 on the surfaces of T cells. Monoclonal antibody HuM291 binds to the CD3 portion of the CD3:TCR (T-cell receptor) complex expressed on the surface of T cells, resulting in apoptosis of antigen-activated T cells., (NCI04) ( NCI )] (UMLS (NCI) C0879551) Anti-CD3 Antibody;
HuM291;
HUM291 [Anti-CD3 Antibody];
MoAb HuM291;
Monoclonal Antibody HuM291 =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 7712. Anterior Temporal Artery
- (UMLS (NCI) C0226228) =Body Part, Organ, or Organ Component
| - 7762. Anti CD7 immunotoxin
- [A toxin linked to an anti-CD7 antibody. ( NCI )] (UMLS (NCI) C0677668) =Pharmacologic Substance; Immunologic Factor
|
- 7713. Anterior Tibial Artery
- (UMLS (NCI) C0085816) =Body Part, Organ, or Organ Component ;
| - 7763. Anti-Adhesion Agent
- [Agents that prevent metastasis by interfering with the aggregation of tumor cells. ( NCI )] (UMLS (NCI) C1510922) =Pharmacologic Substance; ;
|
- 7714. Anterior Tibial Artery Branch
- (UMLS (NCI) C1282115) =Body Part, Organ, or Organ Component
| - 7764. Anti-Adrenal
- [Substances that inhibit the biologic effects of the adrenal hormones by interfering with their synthesis, metabolism, or binding to their receptor sites. ( NCI )] (UMLS (NCI) C0279515) =Pharmacologic Substance
|
- 7715. Anterior Tibial Vein
- (UMLS (NCI) C0226833) =Body Part, Organ, or Organ Component
| - 7765. Anti-Anti-Idiotype
- [antibodies which react with the individual structural determinants (idiotypes) on a particular immunoglobulin (antibody) molecule. ( CSP )] (UMLS (NCI) C0003242) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 7716. Anterior Tongue Carcinoma
- (UMLS (NCI) C1332304) Carcinoma of Anterior Tongue;
Carcinoma of the Anterior Tongue;
=Neoplastic Process ;
| - 7766. Anti-asthmatic Agent
- [Classified as bronchodilators (beta-adrenoreceptor agonists, xanthines, muscarinic-receptor antagonists) and anti-inflammatory agents (glucocorticoids, cromolyn), natural or synthetic Anti-asthmatic Agents relieve asthma (a recurrent airway obstruction) in multiple ways and at various sites, by reducing bronchial spasm, dyspnea, allergic reaction, local inflammation, and pain. Other agents, such as anti-histamine and antibiotics, may also be used in asthma. (NCI04) ( NCI )] (UMLS (NCI) C0282556) =Pharmacologic Substance ;
|
- 7717. Anterior Tongue Mucoepidermoid Carcinoma
- (UMLS (NCI) C1332305) Mucoepidermoid Carcinoma of Anterior Tongue;
Mucoepidermoid Carcinoma of the Anterior Tongue;
=Neoplastic Process ;
| - 7767. anti-B1
- [A murine IgG2 monoclonal antibody directed against the CD20 antigen, found on the surface of B-cells. Tositumomab binds to the CD20 surface membrane antigen, resulting in apoptosis, and may stimulate antitumoral cell-mediated and/or antibody-dependent cytotoxicity. (NCI04) ( NCI )] (UMLS (NCI) C0879399) Anti-CD20 Antibody;
MoAb Anti-B1;
Monoclonal Antibody Anti-B1;
TOSITUMOMAB;
TOSITUMOMAB PREPARATION =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =[AN600] ANTINEOPLASTIC RADIOPHARMACEUTICALS;
Unclassified Ingredients =131-I-Anti-B1 Monoclonal Antibody;
TOSITUMOMAB 14 MG/ML |
- 7718. Anterior Tongue Neoplasm
- (UMLS (NCI) C1332306) Anterior Tongue Tumor;
Neoplasm of Anterior Tongue;
Neoplasm of the Anterior Tongue;
Tumor of Anterior Tongue;
Tumor of the Anterior Tongue =Neoplastic Process ;
| - 7768. anti-B7-1
- [A humanized IgG1 monoclonal antibody directed against CD80, the natural ligand for the T-cell antigen CD28 which mediates T-cell and B-cell adhesion. CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes and is often expressed at low levels on the surfaces of follicular lymphoma cells and other lymphoid malignancies. Galiximab binds to CD80 expressed on the cell surfaces of follicular lymphomas, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC). (NCI04) ( NCI )] (UMLS (NCI) C1098262) anti-CD80 Antibody;
Galiximab;
Monoclonal Antibody IDEC-114 =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 7719. Anterior Tongue SCC
- (UMLS (NCI) C0280298) =Neoplastic Process
| - 7769. Anti-Basement Membrane Glomerulonephritis
- (UMLS (NCI) C1332309) =Disease or Syndrome ;
|
- 7720. Anterior Ulnar Vein
- (UMLS (NCI) C1510915) =Body Part, Organ, or Organ Component ;
| - 7770. Anti-c-ERB-2
- [A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells. Trastuzumab blocks the effects of the growth factor protein HER2, which transmits growth signals to breast cancer cells. ( NCI )] (UMLS (NCI) C0728747) Anti-c-erbB2 Monoclonal Antibody;
Anti-ERB-2;
Anti-erbB-2;
Anti-erbB2 Monoclonal Antibody;
Anti-HER2/c-erbB2 Monoclonal Antibody;
Anti-p185-HER2;
c-erb-2 Monoclonal Antibody;
HER2 Monoclonal Antibody;
MoAb HER2;
Monoclonal Antibody c-erb-2;
Monoclonal Antibody HER2;
rhuMAb HER2;
TRASTUZUMAB;
TRASTUZUMAB PREPARATION =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =[AN000] ANTINEOPLASTICS;
Unclassified Ingredients =TRASTUZUMAB 440 MG;
|
- 7721. Anterior Urethra Malignant Neoplasm
- (UMLS (NCI) C0279930) =Neoplastic Process
| - 7771. anti-Carcinoembryonic Antigen Monoclonal Antibody Fab' Fragment
- [A murine IgG monoclonal Fab fragment antibody labeled with technetium-99m directed against carcinoembryonic antigen (CEA), a protein that is overexpressed by many tumor cell types. For tumors that overexpress CEA, arcitumomab may be used as an adjunct diagnostic imaging tool to obtain prognostic information following resection and to monitor for recurrent disease. (NCI04) ( NCI )] (UMLS (NCI) C0758542) Arcitumomab;
technetium Tc 99m arcitumomab;
=Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid |
- 7722. anterior uveitis
- [Inflammation of the anterior uvea comprising the iris, angle structures, and the ciliary body. Manifestations of this disorder include ciliary injection, exudation into the anterior chamber, iris changes, and adhesions between the iris and lens (posterior synechiae). Intraocular pressure may be increased or reduced. ( MSH )] (UMLS (CSP) C0042165) =Disease or Syndrome =PANUVEITIS;
=Behcet's syndrome;
iridocyclitis;
iritis;
| - 7772. Anti-CD22 Monoclonal Antibody, LL2
- [A murine monoclonal antibody (MoAb) IgG2a, LL2. MoAb LL2 recognizes CD22, a B-lymphocyte-restricted antigen expressed as a cytoplasmic protein in progenitor B cells, and as a cell surface protein in mature B cells. When labeled with radioisotope, MoAb LL2 targets at tumor cells that express CD22 antigen and deliver cytotoxic radiation that may be used to treat B-cell lineage cancers. ( NCI )] (UMLS (NCI) C0281743) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 7723. Anterior Wall of the Bladder
- (UMLS (NCI) C0559280) =Body Part, Organ, or Organ Component
| - 7773. Anti-CD22 Recombinant Immunotoxin BL22
- [An anticancer drug that belongs to the family of drugs called bacterial immunotoxins. BL22 is a bacterial toxic substance linked to an antibody that attaches to tumor cells and kills them. ( NCI )] (UMLS (NCI) C0796473) BL22;
BL22 Immunotoxin;
BL22 Immunotoxin [RFB4(dsFv) - PE38;
Immunotoxin BL22;
RFB4(dsFv)-PE38 Immunotoxin =Organic Chemical; Pharmacologic Substance; Immunologic Factor |
- 7724. Anterior Wall of the Nasopharynx
- (UMLS (NCI) C0225489) =Body Part, Organ, or Organ Component
| - 7774. anti-CD23 Antibody
- [IDEC-152 was developed to decrease the body's response to allergens, thereby affecting diseases related to asthma and allergic disorders. This monoclonal antibody binds to the CD23 receptor, by which IDEC-152 may favorably influence asthma through its selective regulation of IgE production and its inhibition of other inflammatory pathways. ( NCI )] (UMLS (NCI) C1327944) Lumiliximab;
Monoclonal Antibody IDEC-152;
p5E8 =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 7725. Anterior Wall of the Tympanum
- (UMLS (NCI) C1510916) =Body Part, Organ, or Organ Component ;
| - 7775. Anti-CD3 Monoclonal Antibody OKT3
- [A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells. ( NCI )] (UMLS (NCI) C0085379) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =IgG;
[IM600] IMMUNE SUPPRESSANTS =MUROMONAB-CD3 1 MG/ML;
|
- 7726. Antero-Lateral Ascending Tract
- (UMLS (NCI) C1510917) =Body Part, Organ, or Organ Component ;
| - 7776. Anti-CD3 x Anti-HER-2-Neu Bispecific Monoclonal Antibody/Autologous Lymphocytes/Interleukin-2/Sargramostim
- (UMLS (NCI) C1134532) =Therapeutic or Preventive Procedure
|
- 7727. Antero-Lateral Column
- (UMLS (NCI) C1510918) =Body Part, Organ, or Organ Component ;
| - 7777. Anti-CD30 Monoclonal Antibody
- [A genetically-engineered, chimeric mouse-human, anti-CD30 monoclonal antibody with potential antineoplastic activity. Monoclonal antibody SGN-30 specifically binds to the receptor CD-30, a member of the tumor necrosis factor receptor super-family, which may be overexpressed on the surfaces of Hodgkin's lymphoma cells and anaplastic-large cell lymphoma cells. After binding to CD30, this agent interferes with the G1 phase of the cell cycle, thereby inducing growth arrest and apoptosis in susceptible tumor cell populations. ( NCI )] (UMLS (NCI) C1328236) Monoclonal Antibody SGN-30;
SGN-30;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 7728. anterograde transport
- [ ] (UMLS (CSP) C0598952) =Cell Function
| - 7778. Anti-CD33 Immunotoxin
- [An immunoconjugate of the humanized monoclonal antibody hP67.6 chemically linked to a bacterial toxin, N-acetyl-gamma calicheamicin, by 4-acetylphenylacetic acid, with antileukemic property. The monoclonal antibody portion specifically binds to CD33 antigen, a cell surface antigen expressed on normal non-pluripotent hematopoietic stem cells as well as over-expressed on myelogenous leukemia cells. Upon internalization, calicheamicin, an enediyne class antibiotics, is released from the conjugate by hydrolysis, and binds in a sequence specific manner to the minor groove of DNA. Thereby leads to breakage of double-stranded DNA and consequently resulting in cell death. ( NCI )] (UMLS (NCI) C1510923) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
|
- 7729. Anterolateral
- [Denoting the area of the body in front and away from the middle line. ( NCI )] (UMLS (NCI) C0332194) =Spatial Concept
| - 7779. anti-CD45 Monoclonal Antibody BC8
- [A murine IgG1 anti-CD45 monoclonal antibody (MoAb) with immunotherapeutic activity. CD45 antigen, a receptor protein-tyrosine phosphatase essential for T cell development and lymphocyte activation, is expressed on virtually all leukocytes. MoAb BC8 has specificity for hematopoietic tissues and maybe used in targeted immunotherapy. ( NCI )] (UMLS (NCI) C1328195) Monoclonal Antibody BC8 =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 7730. Anterolateral Myocardial Infarction
- (UMLS (NCI) C0262564) =Disease or Syndrome
| - 7780. Anti-CD5 MoAb
- [An immunotoxin consisting of a murine anti-CD5 monoclonal antibody conjugated to the ricin A chain. The anti-CD5 monoclonal antibody component binds to CD5, a T-cell associated antigen, thereby targeting the delivery of the cytotoxic ricin A chain to T-cells. The ricin A chain component binds to T-cells and disrupts ribosomal activity and protein synthesis and induces cell cycle arrest. (NCI04) ( NCI )] (UMLS (NCI) C0287024) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 7731. Anteroseptal Myocardial Infarction
- (UMLS (NCI) C0262565) =Disease or Syndrome
| - 7781. anti-CEA antibody
- [An antibody against carcinoembryonic antigen (CEA), a protein present on certain types of cancer cells. ( NCI )] (UMLS (NCI) C1510924) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
|
- 7732. Antesternal anastomosis of esophagus
- [ ] (UMLS (ICD9CM) C0176738) =Therapeutic or Preventive Procedure
| - 7782. Anti-complement immunofluorescence (ACIF)
- [Immunofluorescence, Anti-Complement ( HL7V3.0 )] (UMLS (HL7) C0201450) =Laboratory Procedure =ObservationMethod;
|
- 7733. Antesternal esophageal anastomosis with interposition of colon
- [ ] (UMLS (ICD9CM) C0176743) =Therapeutic or Preventive Procedure
| - 7783. Anti-CTLA4 Human Monoclonal Antibody CP-675,206
- [A monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen-4 (CTLA4), an antigen that is expressed on activated T-cells and exhibits affinity for B7 co-stimulatory molecules. By binding CTLA4, ipilimumab enhances T-cell activation and blocks B7-1 and B7-2 T-cell co-stimulatory pathways. ( NCI )] (UMLS (NCI) C1367202) Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody;
Ipilimumab;
Ticilimumab =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 7734. Antesternal esophageal anastomosis with interposition of small bowel
- [ ] (UMLS (ICD9CM) C0176741) =Therapeutic or Preventive Procedure
| - 7784. Anti-Cytokine Therapy
- (UMLS (NCI) C0281178) =Therapeutic or Preventive Procedure
|
- 7735. Antesternal esophagoesophagostomy
- [ ] (UMLS (ICD9CM) C0176739) =Therapeutic or Preventive Procedure
| - 7785. Anti-cytotoxic T-lymphocyte-associated antigen-4 monoclonal antibody/gp100 antigen/MART-1 antigen/Montanide ISA-51/tyrosinase peptide
- (UMLS (NCI) C1134494) =Therapeutic or Preventive Procedure
|
- 7736. Antesternal esophagogastrostomy
- [ ] (UMLS (ICD9CM) C0176740) =Therapeutic or Preventive Procedure
| - 7786. Anti-cytotoxic T-lymphocyte-associated antigen-4 monoclonal antibody/gp100 antigen/Montanide ISA-51
- (UMLS (NCI) C1134583) =Therapeutic or Preventive Procedure ;
|
- 7737. Anthelone U
- [polypeptide growth factor that exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and epithelial cells. ( CSP )] (UMLS (NCI) C0242275) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone =Growth Agents;
| - 7787. Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody/Interleukin-2
- (UMLS (NCI) C1327942) =Therapeutic or Preventive Procedure; ;
|
- 7738. Anthozoa
- [class in the phylum Cnidaria, comprised mostly of corals and anemones; members occur only as polyps; the medusa stage is completely absent; includes sea anemones. ( CSP )] (UMLS (CSP) C0596106) =Invertebrate ;
=Cnidaria;
=coral;
| - 7788. Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody/Sargramostim
- (UMLS (NCI) C1327994) =Therapeutic or Preventive Procedure ;
|
- 7739. Anthra(1,9-cd)pyrazol-6(2H)-one, 5-((3-aminopropyl)amino)-7,10-dihydroxy-2-(2-((2-hydroxyethyl)amino)ethyl)
- [An anthrapyrazole antineoplastic antibiotic. Piroxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Although less cardiotoxic than doxorubicin, this agent exhibits a narrow spectrum of antineoplastic activity. (NCI04) ( NCI )] (UMLS (NCI) C0069736) =Organic Chemical; Pharmacologic Substance
| - 7789. Anti-DNA Antibody
- [One of a number of antinuclear autoantibodies. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease. ( NCI )] (UMLS (NCI) C0282056) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
|
- 7740. Anthra(1,9-cd)pyrazol-6(2H)-one,7,10-dihydroxy-2-(2-((2-hydroxyethyl)amino)ethyl)-5-((2-(methylamino)ethyl)amino Dihydrochloride
- [The hydrochloride salt of an anthrapyrazole antineoplastic antibiotic. Teloxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair, as well as RNA and protein synthesis ( NCI )] (UMLS (NCI) C0970561) Moxantrazole Hydrochloride;
Teloxantrone Hydrochloride =Organic Chemical; Pharmacologic Substance ;
| - 7790. Anti-Dopamine-b-Hydroxylase Monoclonal Antibody-Saporin
- [An immunoconjugate of the anti-dopamine-b-hydroxylase monoclonal antibody covalently linked to the ribosome-inactivating protein (RIP) saporin derived from Saponaria officinalis. The monoclonal antibody component recognizes and attaches to the membrane-associated antigen, dopamine-b-hydroxylase, resulting in the conjugate being internalized by receptor-mediated endocytosis. The saporin toxin is then released from the complex, and binds to ribosomal subunits, thereby halts protein synthesis, and results in cell death. This immunoconjugate targets the dopamine-beta-hydroxylase enzyme localized on adrenergic nerves in the brainstem particular medulla and pons, thereby could be used to study neurodegenerative disorders and/or address fundamental neurobiological questions. ( NCI )] (UMLS (NCI) C1510925) DSAP;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 7741. anthracene
- [group of compounds with three aromatic rings joined in linear arrangement. ( CSP )] (UMLS (CSP) C0003162) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid
| - 7791. Anti-F19 Monoclonal Antibody
- [A murine monoclonal antibody (MoAb) against human fibroblast activation protein (FAP). FAP is a 95 kDa cell surface glycoprotein and an inducible tumour stromal antigen of epithelial cancers and of a subset of soft tissue sarcomas. FAP shows a very limited distribution pattern in normal tissues, thereby MoAb F19 has possible diagnostic and therapeutic applications in epithelial cancers. ( NCI )] (UMLS (NCI) C0796524) Anti-FAP (Fibroblast Activation Protein), F19 Epitope, Monoclonal Antibody;
F19 monoclonal antibody;
MoAb F19;
Monoclonal Antibody F19;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 7742. Anthracenedione
- [A subgroup of the family of anticancer drugs called anticancer antibiotics. ( NCI )] (UMLS (NCI) C0003174) =Organic Chemical ;
| - 7792. Anti-Gastrin Therapeutic Vaccine
- [An immunotoxin composed of the hormone gastrin linked to diptheria toxin. It is in phase 3 trials for the treatment of pancreatic cancer. ( NCI )] (UMLS (NCI) C1510926) Neutralize Hormone G17;
Neutralizing G17 Hormone =Pharmacologic Substance; Immunologic Factor ;
|
- 7743. anthracosilicosis
- [A mixed condition of anthracosis and silicosis. (Dorland, 27th ed) ( MSH )] (UMLS (CSP) C0003164) =Disease or Syndrome ;
| - 7793. anti-HBc
- [An antibody produced by B lymphocytes to the hepatitis B core antigen as part of the immune response to hepatitis B viral infection. ( NCI )] (UMLS (NCI) C0369330) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 7744. Anthracosis
- (UMLS (NCI) C0003165) =Disease or Syndrome ;
| - 7794. anti-HBs
- [An antibody produced by B lymphocytes to the hepatitis B surface antigen as part of the immune response to hepatitis B viral infection. ( NCI )] (UMLS (NCI) C0369334) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 7745. anthracycline
- [organic compounds with a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine. ( CSP )] (UMLS (CSP) C0003234) =Organic Chemical; Antibiotic
| - 7795. Anti-human Chorionic Gonadotropin Vaccine
- [A synthetic peptide vaccine containing an epitope of the human chorionic gonadotropin beta-subunit with potential antineoplastic activity. Human chorionic gonadotropin (hGC), a hetrodimeric alpha/beta glycoprotein, is secreted by trophoblastic cells during normal gestation and is also an oncofetal tumor antigen. Elevated serum levels of free beta-hCG are seen with trophoblastic and germ cell tumors as well as with some solid tumors such as breast, prostate, colon, pancreatic, renal and lung cancer. The hCG hormone may play a role in tumor progression by functioning as a transforming growth factor, an inducer of metastasis, and as an angiogenesis factor. Vaccination with anti-hCG beta-subunit vaccine may elicit both a humoral and a cellular immune response against hCG-expressing tumor cells, resulting in decreased tumor cell growth. Anti-hCG vaccines have previously been evaluated as anti-fertility or alternative contraceptive treatments. ( NCI )] (UMLS (NCI) C0879548) =Pharmacologic Substance; Biologically Active Substance
|
- 7746. anthranilate
- [ ] (UMLS (CSP) C0103465) =Organic Chemical; Pharmacologic Substance
| - 7796. Anti-human chorionic gonadotropin vaccine/Gemcitabine
- (UMLS (NCI) C0879549) =Therapeutic or Preventive Procedure
|
- 7747. Anthrapyrazole
- [An antineoplastic antibiotic that intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Anthrapyrazoles may also block cell cycle division. In the presence of electron donors, some anthrapyrazole antibiotics cause single-strand breaks in DNA via photosensitization by visible light. These agents are less cardiotoxic than doxorubicin. (NCI04) ( NCI )] (UMLS (NCI) C0051960) =Organic Chemical; Pharmacologic Substance ;
| - 7797. Anti-Idiotype Specified Monoclonal Antibody
- [A synthetic antibody produced by a genetically homogenous population of hybrid cells (hybridoma) against determinant idiotypes (Id) which usually mimic human epitopes. Anti-Id vaccines may be effective in the treatment of B-cell lymphomas, resulting in tumor regression. Anti-idiotype vaccine therapy is less likely to induce autoimmunity if the target antigen is not normally expressed on normal tissues. Monoclonal antibodies have become powerful tools for tumor targeting, recognizing different protein markers on certain cancer cells and may be used alone or as delivery agents for drugs, toxins or radioactive material targeted to tumors. (NCI04) ( NCI )] (UMLS (NCI) C1510927) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
|
- 7748. Anthrapyrazole Antibiotic
- [A class of antibiotics related to the anthracycline antineoplastic antibiotics. The anthrapyrazole antibiotics intercalate into DNA and interact with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. These agents may also block cell cycle division. In the presence of electron donors, some anthrapyrazole antibiotics cause single-strand breaks in DNA via photosensitization by visible light. These agents are less cardiotoxic than doxorubicin. (NCI04) ( NCI )] (UMLS (NCI) C1510919) Anthrapyrazoles;
=Organic Chemical; Antibiotic | - 7798. anti-idiotype vaccine
- [A vaccine made of antibodies that see other antibodies as the antigen and bind to it. Anti-idiotype vaccines can stimulate the body to produce antibodies against tumor cells. ( NCI )] (UMLS (NCI) C1510928) =Pharmacologic Substance; Immunologic Factor ;
|
- 7749. anthrax
- [infectious bacterial zoonotic disease usually acquired by ingestion of Bacillus anthracis; marked by hemorrhage and serous effusions in the organs and cavities and symptoms of extreme prostration. ( CSP )] (UMLS (CSP) C0003175) =Disease or Syndrome ;
| - 7799. Anti-idiotypic Monoclonal Antibody BEC2
- [A murine anti-idiotypic monoclonal antibody (anti-Id MoAb) that directed against an idiotype mimicking a disialoganglioside GD3. GD3 represents a major surface marker on most human melanoma cells. Due to poor immunogenicity of GD3, anti-Id MoAb BEC2 (Ab2) was raised against a mouse anti-GD3 MoAb, R24 (Ab1). This anti-Id MoAb was shown to be functionally mimicking GD3 in stimulating immune response to produce Ab3 that maybe used in combination with other adjuvants for treatment of melanomas. ( NCI )] (UMLS (NCI) C0281550) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 7750. anthrax
- [vaccines or candidate vaccines used to prevent anthrax infection. ( CSP )] (UMLS (HL7) C0358297) =Pharmacologic Substance; Immunologic Factor =bacterial vaccine;
Vaccines administered (code = CVX)(parenteral, unless oral is noted);
VaccineType;
| - 7800. Anti-IgE Monoclonal Antibody E25
- [A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor. (NCI04) ( NCI )] (UMLS (NCI) C0910794) IGE 025;
Olizumab;
rhuMAb-E25;
=Amino Acid, Peptide, or Protein; Immunologic Factor |
home 
Armenian-English 
top