[A murine IgG1 anti-CD45 monoclonal antibody (MoAb) with immunotherapeutic activity. CD45 antigen, a receptor protein-tyrosine phosphatase essential for T cell development and lymphocyte activation, is expressed on virtually all leukocytes. MoAb BC8 has specificity for hematopoietic tissues and maybe used in targeted immunotherapy. ( NCI )]
UMLS (NCI) C1328195Monoclonal Antibody BC8
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor