- 7901. Antiestrogen Therapy
- (UMLS (NCI) C0854638) =Therapeutic or Preventive Procedure ;
| - 7951. antileukemic agent
- [substance that inhibits the development of or prevents leukemia. ( CSP )] (UMLS (CSP) C0596112) =Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS; |
- 7902. antifibrinolytic agent
- [agents that prevent fibrinolysis or lysis of a blood clot or thrombus; several endogenous antiplasmins are known; these agents are used to control massive hemorrhage and in other coagulation disorders. ( CSP )] (UMLS (CSP) C0003304) =Pharmacologic Substance ;
| - 7952. antileukocyte isoantibody
- [ ] (UMLS (CSP) C0596113) =Amino Acid, Peptide, or Protein; Immunologic Factor =isoantibody;
|
- 7903. Antiflatulent Agent
- [Natural or synthetic compounds usually administered orally, Antiflatulent Agents relieve or prevent flatulence, excess gas in the stomach and intestines, by adsorbing the gas, stimulating intestinal elimination of gas, or preventing gas formation. Alpha-galactosidase and activated charcoal are used against flatulence. (NCI04) ( NCI )] (UMLS (NCI) C0003305) =Pharmacologic Substance ;
| - 7953. Antimetabolic agents affecting fetus or newborn via placenta or breast milk
- [ ] (UMLS (ICD9CM) C1561786) MAT ANTIMETABOL AFF NB;
=Pathologic Function |
- 7904. antifoaming agent
- [Agents used to prevent the formation of foam or to treat flatulence or bloat. ( MSH )] (UMLS (CSP) C0003306) =Chemical Viewed Functionally ;
| - 7954. antimetabolite
- [drug that is chemically similar to a naturally occurring metabolite, but differs enough to interfere with normal metabolic pathways. ( CSP )] (UMLS (CSP) C0003376) =Pharmacologic Substance
|
- 7905. antifolate
- [inhibitors of the enzyme, dihydrofolate reductase, which converts dihydrofolate to tetrahydrofolate; frequently used in cancer chemotherapy. ( CSP )] (UMLS (NCI) C0016411) =Pharmacologic Substance =antimetabolite;
Inhibitors, Nucleic Acid Synthesis; vitamin antagonist; =4-Aminofolic acid; 4-Amino-10-methylfolic Acid; Thymidylate Synthase Inhibitor; DHFR Inhibitor; | - 7955. antimicroorganism antibody
- [immunoglobulins induced by exposure to microorganism antigens. ( CSP )] (UMLS (CSP) C0596114) =Amino Acid, Peptide, or Protein; Immunologic Factor =Ab;
=antibacterial antibody; antifungal antibody; antiviral antibody; |
- 7906. antifreeze
- [ ] (UMLS (CSP) C0598248) =Substance ;
| - 7956. antimitotic
- [agent that inhibits or prevents mitosis. ( CSP )] (UMLS (CSP) C0003379) =Pharmacologic Substance
|
- 7907. antifungal antibiotic
- [antibiotics inhibiting the growth of or killing fungi and used in the treatment of various fungal diseases. ( CSP )] (UMLS (CSP) C0003235) =Antibiotic ;
| - 7957. antimony
- [metallic element, atomic symbol Sb, atomic number 51, and atomic weight 121.75; used as a metal alloy; forms various medicinal and poisonous salts; toxic and an irritant to the skin and the mucous membranes. ( CSP )] (UMLS (CSP) C0003380) =Element, Ion, or Isotope
|
- 7908. antifungal antibody
- [immunoglobulins induced by exposure to fungal antigens. ( CSP )] (UMLS (CSP) C0003245) =Amino Acid, Peptide, or Protein; Immunologic Factor
| - 7958. Antimony Sodium Gluconate
- [Antimony complex where the metal may exist in either the pentavalent or trivalent states. The pentavalent gluconate is used in leishmaniasis. The trivalent gluconate is most frequently used in schistosomiasis. ( MSH )] (UMLS (NCI) C0003383) =Organic Chemical; Pharmacologic Substance ;
|
- 7909. Antifungal Therapy
- (UMLS (NCI) C0678026) =Therapeutic or Preventive Procedure ;
| - 7959. Antimuscarinic Agent
- [Natural or synthetic Antimuscarinic Agents inhibit acetylcholine neurotransmitter action at muscarinic receptors. Antimuscarinic drugs are used as antiarrhythmic, antiparkinson, antiasthmatic, and antispasmodic agents, as well as antidote of the natural mushroom alkaloid muscarine (Amanita muscaria) or to prevent parasympathetic stimulation at neuroeffector junctions. (NCI04) ( NCI )] (UMLS (NCI) C0003385) =Pharmacologic Substance
|
- 7910. antigen
- [any substance recognized by the immune system and inducing an immune reaction. ( CSP )] (UMLS (CSP) C0003320) =Immunologic Factor
| - 7960. antimycin
- [ ] (UMLS (CSP) C0052078) =Organic Chemical; Antibiotic ;
|
- 7911. Antigen AC133
- [Prominin-1 protein (865 aa, ~97 kDa) is encoded by the KIF4A gene. This protein may play a role in hematopoiesis, but an exact function has yet to be elucidated. The protien has been implicated in tumor pathogenesis and formation in several cancers, including retinoblastoma, hemangioma, and glioblastoma phenotypes. Additionally, the protein has been used as a marker to distinguish cells that have the potential to become cancerous from the larger normal cell population. ( NCI )] (UMLS (NCI) C0673028) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
| - 7961. Antin
- [An ethanolamine derivative with antihistaminic property. Phenyltoloxamine blocks H1 histamine receptors, thereby inhibiting phospholipase A2 and production of endothelium-derived relaxing factor, nitric oxide. Subsequent lack of activation of guanylyl cyclase through nitric oxide results in decreased cyclic GMP levels, thereby inhibiting smooth muscle constriction of various tissues, decreasing capillary permeability and decreasing other histamine-activated allergic reactions. ( NCI )] (UMLS (NCI) C0070709) =Organic Chemical; Pharmacologic Substance ;
=Benzhydryl Compounds; [AH900] ANTIHISTAMINES, OTHER =PHENYLTOLOXAMINE CITRATE; PHENYLTOLOXAMINE RESIN COMPLEX; PHENYLTOLOXAMINE CITRATE; PHENYLTOLOXAMINE RESIN COMPLEX; PHENYLTOLOXAMINE 10 MG/5ML; PHENYLTOLOXAMINE 50 MG; PHENYLTOLOXAMINE 30 MG; PHENYLTOLOXAMINE DIHYDROGENCITRATE; PHENYLTOLOXAMINE RESINCOMPLEX; PHENYLTOLOXAMINECITRATE; PHENYLTOLOXAMINEDIHYDROGEN CITRATE |
- 7912. antigen antibody affinity
- [A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes. ( MSH )] (UMLS (CSP) C0003255) =Molecular Function ;
| - 7962. antinematodal agent
- [Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice. ( MSH )] (UMLS (CSP) C0003391) =Pharmacologic Substance
|
- 7913. antigen antibody binding
- [ ] (UMLS (CSP) C0597878) =Molecular Function ;
| - 7963. ANTINEOPLASTIC CHEMO ENC
- [ ] (UMLS (ICD9CM) C1561677) Encounter for antineoplastic chemotherapy;
=Finding |
- 7914. antigen antibody complex
- [product of an antigen antibody reaction; may also contain complement. ( CSP )] (UMLS (CSP) C0003313) =Amino Acid, Peptide, or Protein; Immunologic Factor
| - 7964. Antineoplastic Vaccine
- [A vaccine designed to prevent or treat cancer. ( NCI )] (UMLS (NCI) C0376659) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 7915. antigen antibody reaction
- [immune response induced by binding antigen to antibody. ( CSP )] (UMLS (CSP) C0003314) =Molecular Function ;
| - 7965. Antineoplaston AS2-1
- [A 4:1 mixture of phenylacetate and phenylacetylgluatmine, degradation products of the antineoplaston agent A10. Antineoplaston AS2-1 inhibits the incorporation of L-glutamine into tumor-cell proteins, leading to cell cycle arrest in the G1 phase and inhibition of mitosis. This agent may also inhibit RAS oncogene expression and activate tumor suppressor gene p53, resulting in cell differentiation and apoptosis. (NCI04) ( NCI )] (UMLS (NCI) C0294295) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
|
- 7916. Antigen Binding
- [Antigen Binding Interaction involves specific and high affinity non-covalent interaction (binding) of an endogenous antibody through intermolecular physical forces of attraction and spatial complementarity with a soluble or particulate substance (antigen) that induces an immune response. ( NCI )] (UMLS (NCI) C1148575) =Molecular Function ;
| - 7966. antioncogene
- [genes whose loss or deactivation leads to neoplastic transformation; compare with ONCOGENE and PROTOONCOGENE. ( CSP )] (UMLS (CSP) C0079427) =Gene or Genome ;
=gene; =brca gene; p53 gene/protein |
- 7917. Antigen Binding Fragment
- [Part of an immunoglobulin antibody that binds a specific antigen and consists of both a light chain and part of a heavy chain. By comparison, natural antibodies consist of two heavy and two light chains. An FAB (fragment antibody) offers the advantages of smaller size and lower cross-reactivity compared to the complete antibody. (NCI04) ( NCI )] (UMLS (NCI) C0021031) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
=Immunoglobulin Fragments; =abciximab | - 7967. antioxidant
- [naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added; counteract the harmful and damaging effects of oxidation. ( CSP )] (UMLS (CSP) C0003402) =Pharmacologic Substance
|
- 7918. Antigen CD61
- [Widely expressed by human ITGB3 Gene (ITGB Family), type I membrane protein Integrin Beta 3 contains a VWFA-like domain and is involved in cell adhesion and signaling. Multiple heterodimeric alpha/beta combinations result in different integrins. ITGB3 associates with alphaIIB or alphaV and recognize RGD; aIIB/beta-3 also recognizes HHLGGGAKQAGDV in FN gamma. Beta-3C interacts with FLNB. aV/beta-3 is a receptor for cytotactin, fibronectin, laminin, MMP-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin, and von Willebrand factor. Receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin, and vitronectin, aIIB/beta-3 binds fibrinogen to induce platelet aggregation and plug ruptured endothelia. In response to platelet aggregation, Tyr-773/785 phosphorylated ITGB3 appears to bind GRB2/SHC. ITGB3 defects cause Glanzmann thrombasthenia (GT). (NCI) ( NCI )] (UMLS (NCI) C0638262) =Amino Acid, Peptide, or Protein; Receptor
| - 7968. antiphospholipid antibody syndrome
- [associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses; involves the presence of antibodies directed against phospholipids; cardiolipins show markedly elevated levels of anticardiolipin antibodies; present also are high levels of lupus anticoagulant; in pregnancy it can cause abortion. ( CSP )] (UMLS (CSP) C0085278) =Disease or Syndrome =autoimmune disease;
syndrome |
- 7919. Antigen CD82
- [Kangai 1 Protein, a metastasis suppressor protein encoded by the 80 kb human KAI1 gene (TM4SF family), is expressed in many tissues and has four putative transmembrane domains and a large extracellular domain having three potential N-glycosylation sites. KAI1 appears to be up regulated in activated T-cells. p53 activates the gene by interacting with sequences in a 5-prime upstream region. Loss of p53 appears to cause down-regulation of KAI1. Similar to leukocyte cell surface glycoproteins involved in cell adhesion and signal transduction, KAI1 is a likely homologue of mouse leukocyte surface antigen R2. Associated with CD4 or CD8, KAI1 delivers co-stimulatory signals for the TCR/CD3 pathway. KAI1 expression at the transcription or posttranscription level is often down regulated during tumor progression. (from SWISS-PROT, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0286983) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 7969. Antiplatelet Agent
- [An agent that inhibits platelet aggregation and reduces coagulation in the circulatory system. ( NCI )] (UMLS (NCI) C0085826) =Pharmacologic Substance ;
|
- 7920. antigen challenge
- [ ] (UMLS (CSP) C0597750) =Therapeutic or Preventive Procedure ;
| - 7970. antiplatyhelmintic agent
- [Agents used to treat cestode, trematode, or other flatworm infestations in man or animals. ( MSH )] (UMLS (CSP) C0003414) =Pharmacologic Substance
|
- 7921. Antigen Identified by Monoclonal Antibody Ki-67
- [Antigen Identified by Monoclonal Antibody Ki-67, encoded by the MKI67 gene, is a nuclear antigen expressed in proliferating cells but not in quiescent cells, and required for maintaining cell proliferation. Expression of this antigen occurs preferentially during late G1, S, G2, and M phases of the cell cycle, while in cells in G0 phase the antigen cannot be detected. Consequently, the monoclonal antibody Ki-67 is used in tumor pathology to detect proliferating cells in neoplastic diseases. This antigen is located in the nucleus, predominantly localized in the G1 phase in the perinucleolar region. In the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes. This antigen contains 1 FHA domain. Two alternative splicing forms exist, Long and Short. (from Swiss-Prot) ( NCI )] (UMLS (NCI) C0208804) =Amino Acid, Peptide, or Protein; Immunologic Factor; Indicator, Reagent, or Diagnostic Aid
| - 7971. antiport
- [cotransport of two solutes across a biological membrane in opposite directions, mediated by specific membrane pump proteins which may be ATP- or gradient-driven. ( CSP )] (UMLS (CSP) C1153198) =Cell Function =biological transport;
|
- 7922. Antigen Identified by Monoclonal Antibody Ki-67 Gene
- [This gene is involved in cellular proliferation. ( NCI )] (UMLS (NCI) C1334508) MKI67;
MKI67 Gene; =Gene or Genome ; | - 7972. antiporter
- [Membrane transporters that co-transport two or more dissimilar molecules in the opposite direction across a membrane. Usually the transport of one ion or molecule is against its electrochemical gradient and is "powered" by the movement of another ion or molecule with its electrochemical gradient. ( MSH )] (UMLS (CSP) C0052088) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 7923. Antigen LB39-AA
- [Expressed in melanocytes and retina by human MLANA Gene, 118-aa 13-kDa Pro-rich Melan-A Protein is an antigen recognized by cytolytic T lymphocytes that contains no leader sequence but has a putative transmembrane hydrophobic stretch, that may bind HLA-A2, followed by 3 Arg residues. (NCI) ( NCI )] (UMLS (NCI) C0385723) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 7973. Antiprogestational Therapy
- (UMLS (NCI) C0280531) =Therapeutic or Preventive Procedure
|
- 7924. antigen presentation
- [process by which an antigen is presented to lymphocytes in a form they can recognize; antigen presenting cells may ingest or digest the antigen and present the fragments to the cell surface for recognition by the lymphocytes. ( CSP )] (UMLS (CSP) C0206431) =Cell Function =immune modulation;
=leukocyte activation/transformation; lymphocyte proliferation | - 7974. Antiprolactin Therapy
- (UMLS (NCI) C0281149) =Therapeutic or Preventive Procedure
|
- 7925. Antigen Processing
- [The process by which foreign molecules are taken up by antigen presenting cells, proteolytically cleaved, and displayed on the cell surface in complex with MHC molecules. ( NCI )] (UMLS (NCI) C0206430) =Cell Function
| - 7975. Antipsychotic Medications
- (UMLS (HL7) C1548819) =Health Care Activity =Consent Type;
|
- 7926. Antigen Proliferation Assay
- [An in vitro test of T-cell function ( NCI )] (UMLS (NCI) C0201614) =Laboratory Procedure
| - 7976. antipyrine
- [family of N-phenylpyrazolones with nonnarcotic analgesic properties. ( CSP )] (UMLS (CSP) C0003420) =Organic Chemical; Pharmacologic Substance ;
|
- 7927. antigen receptor
- [family of immunoglobin-like lymphocyte surface molecules that mediate activation of lymphocytes by antigens. ( CSP )] (UMLS (CSP) C0034788) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor =Cytoplasmic Receptor;
=B cell receptor; Major Histocompatibility Complex Receptor; | - 7977. antireceptor antibody
- [autoantibodies against cell surface receptors; for example, those directed against acetylcholine receptors in myasthenia gravis and against TSH receptors in Graves disease; also includes antibodies formed in one organism and used against receptors in a different organism. ( CSP )] (UMLS (CSP) C0596115) =Amino Acid, Peptide, or Protein; Immunologic Factor =Ab;
|
- 7928. antigen registry
- [ ] (UMLS (CSP) C1331067) =Health Care Related Organization
| - 7978. antiretroviral agent
- [Agents used to treat RETROVIRIDAE INFECTIONS. ( MSH )] (UMLS (CSP) C0599685) =Pharmacologic Substance ;
|
- 7929. antigen resource
- [ ] (UMLS (CSP) C1331068) =Health Care Related Organization
| - 7979. antischizophrenic
- [ ] (UMLS (CSP) C0597884) =Pharmacologic Substance ;
|
- 7930. antigen specificity
- [ ] (UMLS (CSP) C1536991) =Molecular Function
| - 7980. Antisense Agents
- [Antisense Oligonucleotides, short synthetic segments of DNA or RNA, designed with a sequence complimentary to a specific mRNA that target and bind with mRNA, causing inhibition of translation or overexpression of the protein encoded by the mRNA. ( NCI )] (UMLS (NCI) C0079925) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance; Indicator, Reagent, or Diagnostic Aid
|
- 7931. antigen, gp209-2m
- [A modified peptide antigen derived from gp209, with potential immunomodulatory and antineoplastic activities. gp209-2M antigen (IMDQVPFSV) has a methionine substitution of threonine at position 2 of gp209 peptide (ITDQVPFSV), which is the immunogenic epitope of human melanoma tumor glycoprotein gp100. Vaccination with this peptide may evoke a cytotoxic T lymphocyte (CTL) response against tumor cells expression the gp100 antigen. ( NCI )] (UMLS (NCI) C0338352) =Pharmacologic Substance; Immunologic Factor
| - 7981. antisense nucleic acid
- [naturally occurring complementary RNA which regulates gene expression by binding to mRNA; or, DNA of genes which code acoantisense RNA; or, synthetic complementary DNA or RNA probes based on antisense sequences. ( CSP )] (UMLS (CSP) C0078973) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance; Indicator, Reagent, or Diagnostic Aid =Nucleic Acid;
=siRNA; MicroRNA; |
- 7932. Antigen, Prostate-Specific
- [PSA. A substance produced by the prostate that may be found in an increased amount in the blood of men who have prostate cancer, benign prostatic hyperplasia, or infection or inflammation of the prostate. ( NCI )] (UMLS (NCI) C0138741) =Amino Acid, Peptide, or Protein; Enzyme; Immunologic Factor =kallikrein;
| - 7982. Antisense Oligonucleotide Therapy
- (UMLS (NCI) C0935882) Antisense Therapy =Therapeutic or Preventive Procedure
|
- 7933. Antigen, Thomsen-Friedenreich
- [A type 1 core O-glycan with potential immunotherapeutic property. Thomsen-Friedenreich (TF) antigen, a galactose disaccharide, is normally O-linked to serine or threonine residue of mucins (MUC1), a transmembrane glycoprotein overexpressed on epithelial cell surface of a variety of tumor cells. The expression of this antigen is associated with tumor cell adhesion, tissue invasion and aggressiveness. When administered in a vaccine formulation, TF antigen may stimulate a cytotoxic T cell response against tumors expressing TF epitope, which may result in a reduction in tumor size. ( NCI )] (UMLS (NCI) C0053438) =Immunologic Factor
| - 7983. Antisense to ERCC-1
- [The 3-prime terminus of human ERCC1, a DNA repair gene, overlaps the 3-prime end of Antisense to ERCC-1 Gene. This exceptional type of overlap is conserved in mouse and even in yeast RAD10, an ERCC1 homolog, suggesting an important biologic function. ASE1 appears to encode a 399-amino acid 43 kD ASE1 Protein. (Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1366482) ASE-1;
CAST; CD3-Epsilon-Associated Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 7934. antigenic determinant
- [The simplest form of an antigenic determinant, on a complex antigenic molecule, which can combine with antibody or T cell receptor. ( NCI )] (UMLS (CSP) C0003316) =Immunologic Factor
| - 7984. antisepsis
- [prevention of infection by means of agents that inhibit or kill infectious microorganisms on environmental surfaces or a body surface such as skin or mucous membranes. ( CSP )] (UMLS (CSP) C0003424) =Therapeutic or Preventive Procedure
|
- 7935. antigenic peptide transporter
- [transmembrane transporters located as a complex anchored in the endoplasmic reticulum membrane; functions as an ATP dependent peptide pump to convey short peptides into the endoplasmic reticulum. ( CSP )] (UMLS (CSP) C0597880) =Amino Acid, Peptide, or Protein; Biologically Active Substance =membrane transport protein;
| - 7985. antiseptic sterilization
- [substances or processes used on humans, other animals, or food that destroy harmful microorganisms or inhibit their activity; distinguished from DISINFECTANT, which is used on inanimate objects. ( CSP )] (UMLS (CSP) C0596116) =Occupational Activity ;
=antisepsis; |
- 7936. Antigenic Surface Determinant Protein OA3
- [CD47 Antigen, encoded by the CD47 gene, is a 50-kD membrane protein with an amino-terminal immunoglobulin domain and a carboxyl-terminal multiple-membrane-spanning region. CD47 Antigen is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is also involved in membrane permeability changes induced following virus infection. Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior. The interaction of CD47 with SHPS-1 may contribute to the recruitment of B lymphocytes via endothelial cells under steady state conditions. CD47 Antigen is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. Four isoforms are produced by alternative splicing. (From LocusLink, OMIM, Swiss-Prot and NCI) ( NCI )] (UMLS (NCI) C0220248) =Amino Acid, Peptide, or Protein; Immunologic Factor =CD antigen;
| - 7986. antiserum registry
- [ ] (UMLS (CSP) C1331069) =Health Care Related Organization
|
- 7937. antiglaucoma drug
- [agent used to reduce elevated intraocular pressure. ( CSP )] (UMLS (CSP) C0597128) =Pharmacologic Substance ;
=[OP000] OPHTHALMIC AGENTS; =forskolin; | - 7987. antiserum resource
- [ ] (UMLS (CSP) C1331070) =Health Care Related Organization
|
- 7938. antiglobulin test
- [Hemagglutination test in which Coombs' reagent (antiglobulin, or anti-human globulin rabbit immune serum) is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which have been coated with antibody in vivo (e.g., in hemolytic disease of newborn, autoimmune hemolytic anemia, and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection of antibodies not identifiable by other means). (MeSH) ( NCI )] (UMLS (CSP) C0009961) =Laboratory Procedure
| - 7988. Antiserum to Endotoxin Core
- [A murine monoclonal antibody raised against endotoxins of Escherichia coli J5 strain with potential antibacterial activity. Monoclonal J5 reacts with lipid A, the key endotoxic component of the lipopolysaccharides (LPS), found mostly in gram-negative bacteria. By binding to endotoxins, monoclonal J5 prevents the initiation of a cascade of events in host cells, including the production of proinflammatory cytokines that eventually leads to the sepsis syndrome. ( NCI )] (UMLS (NCI) C1134511) Monoclonal J5;
=Pharmacologic Substance |
- 7939. Antihaemophilic Factor
- [antihemophilic factor that is part of the factor VIII/von Willebrand factor complex; produced in the liver and acts in the intrinsic pathway of blood coagulation; serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin. ( CSP )] (UMLS (NCI) C0015506) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance =Blood Coagulation Factor;
Antihaemophilic Factor =Antihaemophilic Factor; ANTIHEMOPHILIC FACTOR,HUMAN; Antihemophilic factor, porcine; ANTIHEMOPHILIC FACTOR,HUMAN,METHOD M,MONOCLONAL; ANTIHEMOPHILIC FACTOR,RECOMBINANT; | - 7989. antisickling agent
- [Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions. ( MSH )] (UMLS (CSP) C0003429) =Pharmacologic Substance
|
- 7940. Antihelix
- (UMLS (NCI) C0229308) =Body Part, Organ, or Organ Component
| - 7990. antisocial personality
- [personality disorder whose essential feature is a pervasive pattern of disregard for, and violation of, the rights of others through aggressive, antisocial behavior, without remorse or loyalty to anyone. ( CSP )] (UMLS (CSP) C0003431) =Mental or Behavioral Dysfunction
|
- 7941. antihemophilic factor B
- [Factor ix is a vitamin k-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor x to its active form in the presence of ca(2+) ions, phospholipids, and factor VIIIa. ( NCI )] (UMLS (CSP) C0015491) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance =Blood Coagulation Factor;
Serine Endopeptidases; [BL500] BLOOD DERIVATIVES; =FACTOR IX COMPLEX,HUMAN; FACTOR IX,RECOMBINANT; FACTOR IX COMPLEX,HUMAN; | - 7991. Antispasmodic Agent
- [agent that relieves spasm, usually of smooth muscles as in arteries, bronchi, intestine, bile duct, or ureters, but also of voluntary muscle. ( CSP )] (UMLS (NCI) C0037766) =Pharmacologic Substance ;
=Drug; |
- 7942. antihemophilic factor C
- [Stable blood coagulation factor involved in the intrinsic pathway. The activated form XIa activates factor IX to IXa. Deficiency of factor XI is often called hemophilia C. ( MSH )] (UMLS (CSP) C0015522) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=Blood Coagulation Factor; Serine Endopeptidases | - 7992. antisperm agent
- [any agent or substance which suppresses, prevents or opposes the formation of spermatozoa. ( CSP )] (UMLS (CSP) C0003433) =Pharmacologic Substance
|
- 7943. Antihistamine
- [Any agent that bind to the histamine-1 (H-1) receptor, thereby antagonizing histamine mediated allergic reactions, such as bronchoconstriction, vasodilation and up-regulated capillary permeability. ( NCI )] (UMLS (NCI) C0019592) =Pharmacologic Substance ;
=Histamine Antagonists; | - 7993. antitermination
- [ ] (UMLS (CSP) C0599945) =Genetic Function
|
- 7944. Antihormone Agents
- [substance or agent which suppresses, prevents or opposes the actions of hormones. ( CSP )] (UMLS (NCI) C0019927) =Pharmacologic Substance ;
=inhibitor/antagonist; =Androgen Antagonists; Antiestrogen; insulin inhibitor; (aa Beta, 17 beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one; prostaglandin inhibitor; [HS852] ANTITHYROID AGENTS; ACTH inhibitor; corticosteroid inhibitor; | - 7994. antitermination factor
- [ ] (UMLS (CSP) C0599943) =Biologically Active Substance
|
- 7945. antihypercholesterolemic agent
- [agents which reduce or control high cholesterol and bring about lower cholesterol levels in both the blood and the liver. ( CSP )] (UMLS (CSP) C0003277) =Pharmacologic Substance ;
| - 7995. antithrombin
- [endogenous family of proteins belonging to the serpin superfamily that neutralizes the action of thrombin; includes fibrin and antithrombin III. ( CSP )] (UMLS (CSP) C0003440) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance
|
- 7946. antihyperglycemic
- [class of agents which lower blood glucose levels. ( CSP )] (UMLS (CSP) C0020616) =Pharmacologic Substance =Drug;
=1,1-Dimethylbiguanide; sulfonylurea; 5-[[4-[4(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl\-2,4-thiazolidinedione; Rosiglitazone; insulinlike factor; | - 7996. antithrombin I
- [Antithrombin I refers to the capacity of fibrin to absorb or occlude thrombin and thus neutralize (but not inactivate) it. ( MSH )] (UMLS (CSP) C0581800) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 7947. antihyperkinetic agent
- [ ] (UMLS (CSP) C0596111) =Pharmacologic Substance ;
| - 7997. antithrombin III
- [blood glycoprotein which inhibits thrombin and other blood coagulation factors; important to maintenance of normal blood fluidity. ( CSP )] (UMLS (CSP) C0003438) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance
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- 7948. antihypertensive agent
- [agent that reduces high blood pressure. ( CSP )] (UMLS (CSP) C0003364) =Pharmacologic Substance
| - 7998. antithrombogenic surface
- [surfaces or surface coatings which inhibit the formation or development of a thrombus. ( CSP )] (UMLS (CSP) C0596117) =Finding ;
=blood coagulation; biomaterial interface interaction |
- 7949. antiinfective agent
- [substances that kill or prevent the spreading of infectious agents or organisms in order to prevent the spread of infection. ( CSP )] (UMLS (CSP) C0003204) =Pharmacologic Substance ;
| - 7999. antithymocyte globulin
- [(an-tee-THIGH-mo-site GLOB-yoo-lin) A protein used to reduce the risk of or to treat graft-versus-host disease. ( NCI )] (UMLS (NCI) C0003442) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
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- 7950. antiinflammatory agent
- [agent that counteracts or suppresses the inflammatory process. ( CSP )] (UMLS (CSP) C0003209) =Pharmacologic Substance ;
| - 8000. antitoxin
- [antibody against a microbial toxin or an antiserum from animals immunized by injections of a toxin or toxoid, administered as a passive immunizing agent to neutralize a specific microbial toxin. ( CSP )] (UMLS (CSP) C0003445) =Pharmacologic Substance; Immunologic Factor ;
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