- 1. hTLR7
- [Expressed in lung, placenta, spleen, brain, stomach, small intestine, and pre-dendritic cells by human TLR7 Gene (TLR Family), 104-aa 121-kDa (precursor) type I membrane protein Toll-Like Receptor 7 contains a TIR domain and 27 LRR repeats. TLR7 has a fundamental role in pathogen recognition and activation of innate immunity to microbial agents. Sharing structural and functional similarities, highly conserved TLRs recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity. TLR7 likely acts via MyD88 (TIR interaction) and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. (NCI) ( NCI )] (UMLS (CSP) C0971207) TLR7;
Toll-Like Receptor 7 =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor | - 8. HTLV-1 Related Malignancy
- (UMLS (NCI) C1333932) HTLV-1-Related Malignant Neoplasm;
=Neoplastic Process ; |
- 2. hTLR8
- [Expressed in lung, brain, heart, liver, placenta, monocytes, peripheral leukocytes, and CD11c+ immature dendritic cells by human TLR8 Gene (TLR Family), 1041-aa 120-kDa (precursor) type I membrane protein Toll-Like Receptor 8 contains a TIR domain and 24 LRR repeats. TLR8 has a fundamental role in pathogen recognition and activation of innate immunity to microbial agents. Sharing structural and functional similarities, highly conserved TLRs recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity. TLR8 likely acts via MyD88 (TIR interaction) and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. (NCI) ( NCI )] (UMLS (CSP) C0962444) TLR8;
Toll-Like Receptor 8 =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor | - 9. HTLV-I REX Gene
- [Rex gene of the HTLV-I virus. ( NCI )] (UMLS (NCI) C0079556) =Gene or Genome ;
|
- 3. hTLR9
- [ ] (UMLS (CSP) C0962445) =Amino Acid, Peptide, or Protein; Receptor ;
| - 10. HTLV-I TAX Gene
- [Tax gene of the HTLV-I virus. ( NCI )] (UMLS (NCI) C0079559) =Gene or Genome ;
|
- 4. HTLV group
- [ ] (UMLS (CSP) C0920557) =Virus
| - 11. HTLV-II INFECTN OTH DIS
- [ ] (UMLS (ICD9CM) C0375020) =Disease or Syndrome
|
- 5. HTLV I
- [A retrovirus that infects T-cells (a type of white blood cell) and can cause leukemia and lymphoma. HTLV-1 is spread by sharing syringes or needles used to inject drugs, through sexual contact, and from mother to child at birth or through breast-feeding. ( NCI )] (UMLS (CSP) C0020094) =Virus ;
=BLV-HTLV Retrovirus; | - 12. HTLV-II REX Gene
- [Rex gene of the HTLV-II virus. ( NCI )] (UMLS (NCI) C0079563) =Gene or Genome ;
|
- 6. HTLV II
- [strain of primate T lymphotropic virus 2 that can transform normal T lymphocytes and can replicate in both T and B cell lines; associated with T cell hairy cell leukemia. ( CSP )] (UMLS (CSP) C0020099) =Virus ;
=BLV-HTLV Retrovirus; | - 13. HTLV-II TAX Gene
- [Tax gene of the HTLV-II virus. ( NCI )] (UMLS (NCI) C0079566) =Gene or Genome ;
|
- 7. HTLV-1 INFECTION OTH DIS
- [ ] (UMLS (ICD9CM) C0375019) =Disease or Syndrome
| |