- 1. 1H-1,2,3-Triazole-4-carboxamide, 5-amino-1-((3,5-dichloro-4(4-chlorobenzoyl)phenyl)methyl)
- [An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. ( NCI )] (UMLS (NCI) C0064494) =Organic Chemical; Pharmacologic Substance ;
| - 16. HTLV I
- [A retrovirus that infects T-cells (a type of white blood cell) and can cause leukemia and lymphoma. HTLV-1 is spread by sharing syringes or needles used to inject drugs, through sexual contact, and from mother to child at birth or through breast-feeding. ( NCI )] (UMLS (CSP) C0020094) =Virus ;
=BLV-HTLV Retrovirus;
|
- 2. 1H-1,2,4-Triazol-3-Amine
- [A colorless, odorless crystalline, aromatic amine with a bitter taste. Amitrole is a widely used herbicide for nonfood croplands to control annual and perennial grass type weeds, pondweeds and broad leaf. This substance has a very low acute toxicity in humans and is characterized by skin rash, diarrhea, nausea, vomiting and nose bleeds. Amitrole is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0002602) =Organic Chemical; Hazardous or Poisonous Substance
| - 17. HTLV II
- [strain of primate T lymphotropic virus 2 that can transform normal T lymphocytes and can replicate in both T and B cell lines; associated with T cell hairy cell leukemia. ( CSP )] (UMLS (CSP) C0020099) =Virus ;
=BLV-HTLV Retrovirus;
|
- 3. 2,2'-[5-(1H-1,2,4-Triazol-1-ylmethyl)-1,3-phenylene]di(2-methylpropionitrile)
- [An anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Anastrozole is used to decrease estrogen production and suppress the growth of tumors that need estrogen to grow. ( NCI )] (UMLS (NCI) C0290883) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
NITRILE;
Triazoles;
=ANASTROZOLE 1 MG;
| - 18. HTLV-1 INFECTION OTH DIS
- [ ] (UMLS (ICD9CM) C0375019) =Disease or Syndrome
|
- 4. 5-HT-3
- [Serotonin 5-HT-3 Receptor, encoded by the human HTR3 gene, is one of the several different receptors for serotonin (5-hydroxytryptamine, 5-HT), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Whereas all other known serotonin receptor subtypes are G protein-coupled receptors, this receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel. Two isoforms, 1/5-HT3R-AS and 2/5-HT3R-AL, are produced by alternative splicing. (From OMIM, Swiss-Prot and NCI) ( NCI )] (UMLS (NCI) C0295352) =Amino Acid, Peptide, or Protein; Receptor ;
| - 19. HTLV-1 Related Malignancy
- (UMLS (NCI) C1333932) HTLV-1-Related Malignant Neoplasm;
=Neoplastic Process ;
|
- 5. 5HT transporter
- [responsible for accumulation of serotonin in peripheral blood cells, placenta, and lungs. ( CSP )] (UMLS (CSP) C0170657) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=membrane transport protein;
| - 20. HTLV-I REX Gene
- [Rex gene of the HTLV-I virus. ( NCI )] (UMLS (NCI) C0079556) =Gene or Genome ;
|
- 6. 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-
- [A thioxanthene derivative and a dopamine antagonist with antipsychotic property. Thiothixene blocks postsynaptic dopamine receptors in the mesolimbic system and medullary chemoreceptor trigger zone, thereby decreasing dopamine activity leading to decreased stimulation of the vomiting center and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks the D2 somatodendritic autoreceptor, thereby increasing dopamine turnover. Thiothixene possesses weak affinity for the histamine H1 and alpha-adrenergic receptors. ( NCI )] (UMLS (NCI) C0039955) =Organic Chemical; Pharmacologic Substance =Thioxanthenes;
[CN701] PHENOTHIAZINES/RELATED, ANTIPSYCHOTICS =9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-, Dihydrochloride, Dihydrate | - 21. HTLV-I TAX Gene
- [Tax gene of the HTLV-I virus. ( NCI )] (UMLS (NCI) C0079559) =Gene or Genome ;
|
- 7. 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-, Dihydrochloride, Dihydrate
- [The hydrochloride salt form of thiothixene, a thioxanthene derivative and a dopamine antagonist with antipsychotic property. Thiothixene blocks postsynaptic dopamine receptors in the mesolimbic system and medullary chemoreceptor trigger zone, thereby decreasing dopamine activity leading to decreased stimulation of the vomiting center and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks the D2 somatodendritic autoreceptor, thereby increasing dopamine turnover. Thiothixene possesses weak affinity for the histamine H1 and alpha-adrenergic receptors. ( NCI )] (UMLS (NCI) C0304386) =Organic Chemical; Pharmacologic Substance =9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-;
=THIOTHIXENE HYDROCHLORIDE 1 MG;
THIOTHIXENE HYDROCHLORIDE 5 MG;
THIOTHIXENE HYDROCHLORIDE 10 MG;
THIOTHIXENE HYDROCHLORIDE 20 MG;
THIOTHIXENE HYDROCHLORIDE 5 MG/ML;
THIOTHIXENE HYDROCHLORIDE 2 MG/ML;
THIOTHIXENE HYDROCHLORIDE 2 MG | - 22. HTLV-II INFECTN OTH DIS
- [ ] (UMLS (ICD9CM) C0375020) =Disease or Syndrome
|
- 8. H2TF1
- [NF-Kappa B p49/p100 is the precursor of the NFKB p52 subunit. NFKB2 belongs to the Rel/Dorsal family, contains seven ANK repeats, and binds to REL (p65) proteins to form NFKB, which is trapped in the cytoplasm by IkB proteins. IkB phosphorylation by IKBKA or IKBKB activates NFKB via destructive ubiquitination of IkBs. Activated transcription factor NFKB translocates to the nucleus and binds to the consensus Kappa-B enhancer DNA motif in immune response and acute phase reaction genes. (from SWISS-PROT Q00653, OMIM 164012, and NCI) ( NCI )] (UMLS (NCI) C0212691) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 23. HTLV-II REX Gene
- [Rex gene of the HTLV-II virus. ( NCI )] (UMLS (NCI) C0079563) =Gene or Genome ;
|
- 9. HT-29
- [Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells such as the GOBLET CELLS. ( MSH )] (UMLS (NCI) C0282639) =Cell ;
| - 24. HTLV-II TAX Gene
- [Tax gene of the HTLV-II virus. ( NCI )] (UMLS (NCI) C0079566) =Gene or Genome ;
|
- 10. HTC cell
- [immortalized cell line derived from liver carcinoma cells. ( CSP )] (UMLS (CSP) C0598613) =Cell =cell line;
neoplastic cell | - 25. HTML Text
- [For marked-up text according to the Hypertext Mark-up Language. HTML markup is sufficient for typographically marking-up most written-text documents. HTML is platform independent and widely deployed. ( HL7V3.0 )] (UMLS (HL7) C1554986) =Idea or Concept =TextMediaType;
|
- 11. hTERC
- [Telomerase RNA component is the ribonucleic acid subunit of telomerase. Telomerase uses the species-specific RNA sequences as the templates to synthesize GC-rich strand of telomeres, chromosome ends. ( NCI )] (UMLS (NCI) C0935992) hTR;
Telomerase RNA Component;
TERC =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
| - 26. HtmlLinkType
- [HtmlLinkType values are drawn from HTML 4.0 and describe the relationship between the current document and the anchor that is the target of the link ( HL7V3.0 )] (UMLS (HL7) C1553828) =Intellectual Product =CodeSystem;
=alternate;
stylesheet;
start;
next;
prev;
contents;
index;
glossary;
copyright;
chapter;
section;
subsection;
appendix;
help;
bookmark;
|
- 12. hTLR7
- [Expressed in lung, placenta, spleen, brain, stomach, small intestine, and pre-dendritic cells by human TLR7 Gene (TLR Family), 104-aa 121-kDa (precursor) type I membrane protein Toll-Like Receptor 7 contains a TIR domain and 27 LRR repeats. TLR7 has a fundamental role in pathogen recognition and activation of innate immunity to microbial agents. Sharing structural and functional similarities, highly conserved TLRs recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity. TLR7 likely acts via MyD88 (TIR interaction) and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. (NCI) ( NCI )] (UMLS (CSP) C0971207) TLR7;
Toll-Like Receptor 7 =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor | - 27. hToll
- [Expressed most in placenta, spleen, and myelomonocytic leukocytes by human TLR4 Gene (TLR Family), isoforms A-D of 96-kDa (precursor) type I membrane protein Toll-Like Receptor 4 contains a TIR domain and 21 LRR repeats. Sharing structural and functional similarities, highly conserved TLRs recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity. As part of the LPS receptor (with CD14 and LY96), TLR4 mediates the immune response to LPS in gram-negative bacteria. Binding to LY96 via the extracellular domain and to MyD88 and TIRAP via their TIR domains, TLR4 acts via MyD88, TIRAP, and TRAF6, leading to NF-kappa-B activation, cytokine secretion, and the inflammatory response. TLR4 Asn-526 and Asn-575 glycosylation seems necessary for the LPS-response. (NCI) ( NCI )] (UMLS (NCI) C1321919) TLR4;
tlr4 gene product;
TOLL;
Toll Homologue;
Toll-Like Receptor 4;
=Amino Acid, Peptide, or Protein; Receptor |
- 13. hTLR8
- [Expressed in lung, brain, heart, liver, placenta, monocytes, peripheral leukocytes, and CD11c+ immature dendritic cells by human TLR8 Gene (TLR Family), 1041-aa 120-kDa (precursor) type I membrane protein Toll-Like Receptor 8 contains a TIR domain and 24 LRR repeats. TLR8 has a fundamental role in pathogen recognition and activation of innate immunity to microbial agents. Sharing structural and functional similarities, highly conserved TLRs recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity. TLR8 likely acts via MyD88 (TIR interaction) and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. (NCI) ( NCI )] (UMLS (CSP) C0962444) TLR8;
Toll-Like Receptor 8 =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor | - 28. HTS1
- [ST5 protein contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. (from LocusLink) ( NCI )] (UMLS (NCI) C0753627) P126;
P70;
P82;
ST5;
ST5 Protein;
Suppression of Tumorigenicity 5 =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 14. hTLR9
- [ ] (UMLS (CSP) C0962445) =Amino Acid, Peptide, or Protein; Receptor ;
| - 29. HTTP
- [Hypertext Transfer Protocol [RFC 2068].http://www.ietf.org/rfc/rfc2068.txt ( HL7V3.0 )] (UMLS (HL7) C1555015) =Idea or Concept =URLScheme;
|
- 15. HTLV group
- [ ] (UMLS (CSP) C0920557) =Virus
| |
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