- 1. 1(2H)-Phthalazinone Hydrazone
- [direct-acting vasodilator that is used as an antihypertensive. ( CSP )] (UMLS (NCI) C0020223) =Organic Chemical; Pharmacologic Substance =antihypertensive agent;
hydrazine;
Phthalazines;
[CV490] ANTIHYPERTENSIVES, OTHER =HYDRALAZINE HYDROCHLORIDE;
HYDRALAZINE 50 MG | - 32. HPT B ACTE WO CM W DLTA
- [ ] (UMLS (ICD9CM) C0375005) =Disease or Syndrome
|
- 2. 1(2H)-Phthalazinone, 4-((4-Chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, Monohydrochloride
- [The hydrochloride salt form of azelastine, a phthalazinone derivative with antihistaminergic activity. Azelastine hydrochloride competes with histamine for the H1 receptor, thereby diminishing the actions of histamine on effector cells and decreasing the histamine-mediated symptoms of allergic reaction, such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle. ( NCI )] (UMLS (NCI) C0771004) Azelastine Hydrochloride;
AZELASTINE HYDROCHLORIDE PREPARATION;
W-2979M =Organic Chemical; Pharmacologic Substance =AZELASTINE;
=AZELASTINE HYDROCHLORIDE 0.05 %;
AZELASTINE HYDROCHLORIDE 137 MCG/ACTUAT | - 33. HPT B ACTE WO CM WO DLTA
- [ ] (UMLS (ICD9CM) C0375004) =Disease or Syndrome
|
- 3. 1(2H)-Pyrimidinecarboxamide, 5-fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-
- [An antimetabolite (pyrimidine analogue) antineoplastic derivative of 5-fluorouracil. (NCI) ( NCI )] (UMLS (NCI) C0044401) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 34. HPT B CHRN COMA W DLTA
- [ ] (UMLS (ICD9CM) C0375003) =Disease or Syndrome
|
- 4. 15H-Pyrrolol[2,1-f][1,15,4,7,10,20]dioxatetraazacyclotri-cosine, Cyclic Peptide Deriv. (9CI)
- [A cyclic depsipeptide extracted from the Caribbean tunicate Trididemnum cyanophorum. Didemnin B activates caspase, thereby inducing apoptosis, and prevents eukaryotic elongation factor 2 (eEF-2)-dependent translocation, thereby inhibiting protein synthesis. This agent also has immunosuppressive and antiviral properties. (NCI04) ( NCI )] (UMLS (NCI) C0936059) 1-Oxoheptyl]oxy]-2,5-dimethyl-1,3-dioxohexyl]-L-leucyl]- L-prolyl]-N,O-dimethyl-, .phi.-lactone (9CI);
Didemnin;
Didemnin B;
L-Tyrosine, N-[1-[N-[4-[[3-hydroxy-4-[[N-[N-[1-(2-hydroxy-1-oxopropyl)- L-prolyl]-N-methyl-L-leucyl]-L-threonyl]amino-5-methyl- 1-oxoheptyl]oxy]-2,5-dimethyl-1,3-dioxohexyl]-L-leucyl]- L-prolyl]-N,O-dimethyl-, .phi.-lactone (9CI);
L-Tyrosine, N-[1-[N-[4-[[3-Hydroxy-4-[[N-[N-[1-(2-hydroxy-1-oxopropyl)- L-prolyl]-N-methyl-L-leucyl]-L-threonyl]amino-5-methyl-1-oxoheptyl]oxy]-2,5-dimethyl-1,3-dioxohexyl]-L-leucyl]- L-prolyl]-N,O-dimethyl-, .phi.-lactone (9CI);
=Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
| - 35. HPT B CHRN COMA WO DLTA
- [ ] (UMLS (ICD9CM) C0375002) =Disease or Syndrome
|
- 5. 1H-Purin-6-amine
- [6-aminopurine; one of the 5 major bases (with guanine, thymine, cytosine, and uracil) found in nucleic acids. ( CSP )] (UMLS (NCI) C0001407) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
| - 36. HPT B CHRN WO CM W DLTA
- [ ] (UMLS (ICD9CM) C0375007) =Disease or Syndrome
|
- 6. 1H-Purin-6-amine, 2-fluoro- (9CI)
- [A fluorinated heterocyclic 2-ring compound. 2-fluoroadenine is the base moiety for many carbocyclic and acyclic nucleoside analogues, which may be used in antineoplastic studies. ( NCI )] (UMLS (NCI) C0046110) =Nucleic Acid, Nucleoside, or Nucleotide
| - 37. HPT B CHRN WO CM WO DLTA
- [ ] (UMLS (ICD9CM) C0375006) =Disease or Syndrome
|
- 7. 1H-Purine-2,6-diamine
- [One of a number of organic compounds that share a similar purine structure and possess antiviral and antitumor properties. 2,6-Diaminopurine nucleosides are versatile synthetic precursors for specific N-6 modifications of antiviral and antitumor agents. (NCI04) ( NCI )] (UMLS (NCI) C0045587) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 38. HPT C W HEPATIC COMA NOS
- [ ] (UMLS (ICD9CM) C1456265) Unspecified viral hepatitis C with hepatic coma;
=Disease or Syndrome |
- 8. 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compound with 1,2-Ethanediamine(2:1)
- [drug combination that contains theophylline and ethylenediamine; its most common use is in bronchial asthma, but it has been investigated for several other applications. ( CSP )] (UMLS (NCI) C0002575) =Organic Chemical; Pharmacologic Substance
| - 39. HPT C W/O HEPAT COMA NOS
- [ ] (UMLS (ICD9CM) C1456263) Unspecified viral hepatitis C without hepatic coma;
=Disease or Syndrome |
- 9. 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl
- [A xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosine receptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema. ( NCI )] (UMLS (NCI) C0013360) =Organic Chemical; Pharmacologic Substance =3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione;
[RE104] BRONCHODILATORS, XANTHINE-DERIVATIVE;
TO BE DELETED INGREDIENT PREPARATIONS;
=DYPHYLLINE 125 MG/ML;
Dyphylline 20 MG/ML;
DYPHYLLINE 200 MG;
DYPHYLLINE 250 MG/ML;
DYPHYLLINE 400 MG;
DYPHYLLINE 100 MG/15ML;
Dyphylline 10.7 MG/ML;
DYPHYLLINE 100 MG | - 40. HPTPE
- [Encoded by human PTPRE Gene (PTP Family), alternative isoform 642-aa Protein Tyrosine Phosphatase Epsilon Isoform 2 is a cytoplasmic nonreceptor-type PTP with a distinct hydrophilic N-terminus and PTP catalytic domains. Alternative isoform 700-aa 81-kDa (precursor) Protein Tyrosine Phosphatase Receptor Type Epsilon Isoform 1 is a type I membrane protein receptor-type PTP with a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains. Studies of the mouse homolog suggest a regulatory role for PTPRE in RAS related signal transduction pathways, cytokine-induced SATA signaling, and activation of voltage-gated K+ channels. (NCI) More…
|
- 10. 1H-Pyrazole, 4-methyl-
- [A pyrazole with competitive alcohol dehydrogenase inhibitor activity. Fomepizole prevents the metabolism of ethylene glycol and methanol by alcohol dehydrogenase, thereby inhibiting the formation of their toxic metabolites, glycolate and oxalate (from ethylene glycol), and formic acid (from methanol). Fomepizole is indicated for use as an antidote in ethylene glycol and methanol poisoning. (NCI05) ( NCI )] (UMLS (NCI) C0048504) =Organic Chemical; Pharmacologic Substance =Pyrazole Compound;
1H-Pyrazole, 4-methyl-;
[AD900] ANTIDOTES/DETERRENTS, OTHER;
=1H-Pyrazole, 4-methyl-;
FOMEPIZOLE 1 GM/ML;
| - 41. HPTPG
- [Expressed in many tissues (likely developmentally regulated in brain) by human PTPRG Gene (PTP Family), Protein Tyrosine Phosphatase Receptor Type G is a likely type I membrane protein receptor-type PTP with an extracellular region containing an eukaryotic-type CAH domain and a fibronectin type III domain, a single transmembrane region, and two tandem intracytoplasmic catalytic PTP domains. PTPs typically regulate cell growth, differentiation, and mitotic cycle. (NCI) ( NCI )] (UMLS (NCI) C1335555) Protein Tyrosine Phosphatase Gamma;
Protein Tyrosine Phosphatase Receptor Type Gamma Polypeptide;
Protein Tyrosine Phosphatase Receptor Type-G;
PTPG;
PTPRG;
Receptor Tyrosine Phosphatase Gamma;
Receptor-Type Protein Phosphatase Gamma;
RPTPG;
R-PTP-Gamma =Amino Acid, Peptide, or Protein; Receptor |
- 11. 1H-Pyrido(4,3-b)indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2((5-methyl-1H-imidazol-4-yl)methyl)-, Monohydrochloride
- [The chloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron hydrochloride blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly on enteric and nociceptive sensory neurons. Alosteron hydrochloride affects the regulation of visceral pain, decreases gastrointestinal contraction and motility, and decreases gastrointestinal secretions. This drug is used to treat diarrhea-predominant irritable bowel syndrome in women. (NCI05) ( NCI )] (UMLS (NCI) C0291771) =Organic Chemical; Pharmacologic Substance =alosetron;
| - 42. HPV
- [A recombinant vaccine of different types of HPV proteins which are well-conserved within types with a significant inter-type variation. ( NCI )] (UMLS (HL7) C1512511) HPV Vaccine;
Human Papilloma Virus Vaccine =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =Vaccines administered (code = CVX)(parenteral, unless oral is noted);
VaccineType |
- 12. 2(1H)-pyridinone, 4-hydroxy-1-beta-D-ribofuranosyl
- [A synthetic analogue of nucleoside uridine lacking a ring nitrogen in the 3-position. 3-deazauridine inhibits cytidine synthase, thereby reducing intracellular levels of cytidine and deoxycytidine and disrupting DNA and RNA synthesis. This agent may trigger apoptosis and enhance differentiation of neoplastic cells.. (NCI04) ( NCI )] (UMLS (NCI) C0000399) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 43. HPV
- [(pap-ih-LO-ma-VYE-rus) A virus that causes abnormal tissue growth (warts) and is often associated with some types of cancer. ( NCI )] (UMLS (NCI) C0021344) =Virus =Papilloma Virus;
|
- 13. 2(1H)-Pyrimidinone, 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)-
- [A drug being studied for use as an anticancer agent. ( NCI )] (UMLS (NCI) C0877874) Troxacitabine;
=Organic Chemical; Pharmacologic Substance ;
| - 44. HPV 16 E6 Peptide
- [A synthetic peptide sequence of human papillomavirus (HPV) type 16 oncoprotein E6. The E6 oncoprotein is implicated in the tumorigenesis of cervical carcinoma. Vaccination with HPV 16 E6 peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against cells expressing the E6 oncoprotein, resulting in tumor cell lysis. ( NCI )] (UMLS (NCI) C0133938) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 14. 2(1H)-Pyrimidinone, 4-amino-1-[4, 5-dihydroxy- 3-(hydroxymethyl)-2-cyclopenten-1-yl]-
- [A synthetic cyclopentenyl antimetabolite analogue of cytidine with antineoplastic activity and antiviral activity. Cyclopentenyl cytosine competitively inhibits cytidine triphosphate (CTP) synthase, thereby depleting cytidine pools and inhibiting DNA synthesis. This agent may also induce differentiation of some tumor cell types. Cyclopentenyl cytosine's antiviral activity is broad-spectrum. (NCI04) ( NCI )] (UMLS (NCI) C0111606) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 45. HPV DNA Probes
- [DNA probes specific for the identification of human papilloma virus. ( MSH )] (UMLS (NCI) C0012895) =Nucleic Acid, Nucleoside, or Nucleotide; Indicator, Reagent, or Diagnostic Aid
|
- 15. 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-,(2R-cis)-
- [A synthetic nucleoside analog of cytosine with activity against human immunodeficiency virus type 1 reverse transcriptase. Emtricitabine is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate. Emtricitabine 5'-triphosphate inhibits the activity of the HIV-1 reverse transcriptase by competing with the natural substrate deoxycytidine 5'-triphosphate. Incorporation of emtricabine 5'-triphosphate into nascent viral DNA results in chain termination. Emtricitabine 5'-triphosphate is a weak inhibitor of mammalian DNA polymerase alpha, beta, epsilon and mitochondrial DNA polymerase gamma. ( NCI )] (UMLS (NCI) C0909839) EMTRICITABINE;
EMTRICITABINE PREPARATION;
FTC;
=Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =[AM800] ANTIVIRALS;
Unclassified Ingredients =EMTRICITABINE 200 MG;
| - 46. HPV-16
- [A strain of the human papillomavirus virus, (HPV16), has been directly linked to cervical cancer and is significantly associated with invasiveness. The papillomavirus virus constitutes a protein coat (capsid) surrounding a circular, double-stranded DNA organised into coding and non-coding regions, and induces skin and mucosal epithelial lesions. Progression from low- to high-grade neoplasia is often associated with the integration of the HPV16 virus genome into the host chromosome. The event occurs with disruption or deletion of the E2 ORF followed by inactivation of the E2 regulatory protein. ( NCI )] (UMLS (NCI) C0999806) Human Papillomavirus-16;
=Virus |
- 16. 2(1H)-pyrimidinone, tetrahydro-4-hydroxy-1-beta-D-ribofuranosyl-
- [A synthetic pyrimidine nucleoside analogue with biomodulating activity. Tetrahydrouridine increases the efficacy of the radiosensitizer cytochlor (5-chloro-2'-deoxycytidine) by inhibiting the enzyme deoxycytidine monophosphate (dCMP) deaminase and preventing the premature deamination of the cytochlor metabolite 5-chloro-2'-deoxycytidine monophosphate (CldCMP) to 5-chloro-2'-deoxyuridine monophosphate (CldUMP); in turn, this increases tumor concentrations of CldUMP which is then further anabolized and incorporated selectively into tumor DNA as CldU (5-chloro-2'-deoxyuridine). (NCI04) ( NCI )] (UMLS (NCI) C0039677) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 47. HPV-18
- [A strain of the human papillomavirus virus, (HPV18), has been directly linked to cervical cancer and plays a role in the pathogenesis of the disease. The papillomavirus virus constitutes a protein coat (capsid) surrounding a circular, double-stranded DNA organised into coding and non-coding regions, and induces skin and mucosal epithelial lesions. The virus integrates its DNA at specific chromosomal locations, such as 8q24 and 12q15, which harbours both HPV18 and HPV16. The use of molecular markers such as HPV18 DNA type may allow the identification of patients with early stage cervical cancer at high risk for disease recurrence. ( NCI )] (UMLS (NCI) C0999807) Human Papillomavirus-18;
=Virus |
- 17. 2H-pyran-2-one,5,6-dihydro-6-(3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11,-tridecatetraenyl)-,trans
- [An anti-tumor antibiotic isolated from the bacterium Streptomyces pulveraceus. Fostriecin inhibits topoisomerase II catalytic activity, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis in various malignant cell types. This agent also inhibits serine/threonine protein phosphatase type 2A in some tumor cell types, thereby interfering with cellular proliferation and differentiation. (NCI04) ( NCI )] (UMLS (NCI) C0118175) =Organic Chemical; Pharmacologic Substance
| - 48. HPV-6
- [Genital warts caused by HPV 6 and 11 are the most common STD in the United States. Over a million cases are seen per year. ( NCI )] (UMLS (NCI) C1005556) Human Papillomavirus Type 6;
Human Papillomavirus-6 =Virus |
- 18. 4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, Dihydrochloride,(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-
- [The hydrochloride salt form of spectinomycin, an aminocyclitol antibiotic derived from Streptomyces spectabilis with antibacterial property. Spectinomycin hydrochloride binds to the bacterial 30S ribosomal subunit, thereby inhibiting peptide elongation and protein synthesis, consequently leading to bacterial cell death. ( NCI )] (UMLS (NCI) C0887525) Spectinomycin Dihydrochloride;
SPECTINOMYCIN HYDROCHLORIDE;
Spectinomycin Hydrochloride Anhydrous;
SPECTINOMYCIN HYDROCHLORIDE PREPARATION;
Spectogard;
=Organic Chemical; Antibiotic ;
=SPECTINOMYCIN;
=SPECTINOMYCIN HYDROCHLORIDE 2 GM/VIL | - 49. HPV-Related Adenocarcinoma
- (UMLS (NCI) C1334048) Human Papilloma Virus Related Adenocarcinoma;
Human Papilloma Virus-Related Adenocarcinoma;
=Neoplastic Process |
- 19. 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic Acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, Disodium Salt
- [The sodium salt form of nedocromil, a pyranoquinolone derivative with anti-inflammatory properties. Nedocromil sodium inhibits the activation and release of inflammatory mediators (leukotrienes, histamine and prostaglandins) from a variety of cells involved in hypersensitivity reactions, including mast cells, eosinophils, neutrophils, macrophages, monocytes and platelets. As a result, nedocromil sodium inhibits both immediate and late bronchoconstriction, decreases bronchial hyperresponsiveness and inhibits recruitment of other inflammatory cells into the airway epithelium. ( NCI )] (UMLS (NCI) C0886658) FPL 59002KP;
NEDOCROMIL SODIUM;
NEDOCROMIL SODIUM PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=NEDOCROMIL;
=NEDOCROMIL SODIUM 1.75 MG/ACTUAT;
NEDOCROMIL SODIUM 2 %;
| - 50. HPV-Related Anal Squamous Cell Carcinoma
- [An anal squamous cell carcinoma related to infection with sexually transmittable human papilloma virus. ( NCI )] (UMLS (NCI) C1334049) Human Papilloma Virus Related Anal Squamous Cell Carcinoma;
Human Papilloma Virus-Related Anal Squamous Cell Carcinoma;
=Neoplastic Process |
- 20. 4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-
- [A pyrazinoisoquinoline derivative with anthelminthic property. Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm. The result is the formation of granulomas and phagocytosis. ( NCI )] (UMLS (NCI) C0032911) =Organic Chemical; Pharmacologic Substance ;
=Anthelminthics;
2 benzazine =PRAZIQUANTEL 600 MG | - 51. HPV-Related Carcinoma
- (UMLS (NCI) C1334050) Human Papilloma Virus Related Carcinoma;
Human Papilloma Virus-Related Carcinoma;
=Neoplastic Process |
- 21. 4H-Pyrido(1,2-a)pyrimidin-4-one, 9-methyl-3-(1H-tetrazol-5-yl)-, Potassium Salt
- [The potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium exerts its action by blocking the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, histamine and leukotrienes, which are involved in the allergic process. Pemirolast potassium also prevents inflammatory mediator release from eosinophils. ( NCI )] (UMLS (NCI) C0872971) Pemirolast Potassium;
PEMIROLAST POTASSIUM PREPARATION;
PEMIROLAST POTASSIUM UNIDENTIFIED =Organic Chemical; Pharmacologic Substance ;
=Pemirolast;
Unclassified Ingredients | - 52. HPV-Related Cervical Carcinoma
- (UMLS (NCI) C1334051) Human Papilloma Virus Related Cervical Carcinoma;
Human Papilloma Virus-Related Cervical Carcinoma;
=Neoplastic Process |
- 22. 4H-Pyrrolo(3,2-d)pyrimidin-4-one,1,5-dihydro-2-amino-7-(3-pyridinylmethyl)
- [A substance that is being studied for the treatment of cancer. ( NCI )] (UMLS (NCI) C0338278) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
| - 53. HPV-Related Cervical Squamous Cell Carcinoma
- (UMLS (NCI) C1334052) Human Papilloma Virus Related Cervical Squamous Cell Carcinoma;
Human Papilloma Virus-Related Cervical Squamous Cell Carcinoma;
=Neoplastic Process |
- 23. 6H-Purine-6-thione, 2-amino-9-(2-deoxy-.alpha.-D-erythro-pentofuranosyl)-1,9-dihydro- (9CI)
- [A purine analog with potential antineoplastic activity. (NCI04) ( NCI )] (UMLS (NCI) C0051299) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 54. HPV-Related Endocervical Adenocarcinoma
- (UMLS (NCI) C1334053) Human Papilloma Virus Related Endocervical Adenocarcinoma;
Human Papilloma Virus-Related Endocervical Adenocarcinoma;
=Neoplastic Process |
- 24. 6H-Pyrido[4, 3-b]carbazolium, 9-hydroxy-2,5,11-trimethyl-acetate (salt)
- [A derivative of the alkaloid ellipticine isolated from species of the plant family Apocynaceae, including Bleekeria vitensis, a plant with anti-cancer properties. As a topoisomerase II inhibitor and intercalating agent, elliptinium stabilizes the cleavable complex of topoisomerase II and induces DNA breakages, thereby inhibiting DNA replication and RNA and protein synthesis (NCI04) ( NCI )] (UMLS (NCI) C0100593) =Organic Chemical; Pharmacologic Substance ;
| - 55. HPV-Related Esophageal Squamous Cell Carcinoma
- (UMLS (NCI) C1334054) Human Papilloma Virus Related Esophageal Squamous Cell Carcinoma;
Human Papilloma Virus-Related Esophageal Squamous Cell Carcinoma;
=Neoplastic Process |
- 25. 9H-Purine-9-acetaldehyde, .alpha.-(1-formyl-2-hydroxyethoxy)-1,6-dihydro-6-oxo-, (R-(R*, R*))- (9CI)
- [A toxic purine analogue. Inosine dialdehyde inhibits ribonucleotide reductase, resulting in decreased synthesis of DNA, RNA, and proteins, and G2/M-phase cell cycle arrest. This agent also forms stable covalent crosslinks in proteins, thereby inhibiting the activity of enzymes involved in nucleic acid synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0063555) =Organic Chemical; Pharmacologic Substance ;
| - 56. HPV-Related Malignancy
- (UMLS (NCI) C1334055) Human Papilloma Virus-Related Malignancy;
Human Papilloma Virus-Related Malignant Neoplasm;
=Neoplastic Process |
- 26. HPA
- [interaction and feedback in stimulation or suppression of hormones produced in the hypothalamus, pituitary, and adrenal glands. ( CSP )] (UMLS (CSP) C0597719) =Body System ;
=neuroendocrine;
=pituitary adrenal axis;
hypothalamic pituitary axis;
| - 57. HPV-Related Penile Squamous Cell Carcinoma
- (UMLS (NCI) C1334056) Human Papilloma Virus Related Penile Squamous Cell Carcinoma;
Human Papilloma Virus-Related Penile Squamous Cell Carcinoma;
=Neoplastic Process |
- 27. HPA-23
- (UMLS (NCI) C0122297) =Pharmacologic Substance; Inorganic Chemical
| - 58. HPV-Related Squamous Cell Carcinoma
- (UMLS (NCI) C1334057) Human Papilloma Virus Related Squamous Cell Carcinoma;
Human Papilloma Virus-Related Squamous Cell Carcinoma;
=Neoplastic Process |
- 28. HPRT1
- [This gene is involved in purine/pyrimidine metabolism. ( NCI )] (UMLS (NCI) C1415701) HPRT1 Gene;
Hypoxanthine Phosphoribosyltransferase 1 (Lesch-Nyhan Syndrome) Gene =Gene or Genome | - 59. HPV-Related Verrucous Carcinoma
- (UMLS (NCI) C1334058) Human Papilloma Virus Related Verrucous Carcinoma;
Human Papilloma Virus-Related Verrucous Carcinoma;
=Neoplastic Process |
- 29. HPRT2
- [This gene plays a putative role in transcription. ( NCI )] (UMLS (NCI) C1415702) HPRT2 Gene;
Hypoxanthine Phosphoribosyltransferase 2 Gene =Gene or Genome | - 60. HPV-Related Vulvar Squamous Cell Carcinoma
- (UMLS (NCI) C1334059) Human Papilloma Virus Related Vulvar Squamous Cell Carcinoma;
Human Papilloma Virus-Related Vulvar Squamous Cell Carcinoma;
=Neoplastic Process |
- 30. HPT B ACTE COMA W DLTA
- [ ] (UMLS (ICD9CM) C0375001) =Disease or Syndrome
| - 61. HPV16 E7
- (UMLS (NCI) C0069508) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 31. HPT B ACTE COMA WO DLTA
- [ ] (UMLS (ICD9CM) C0375000) =Disease or Syndrome
| - 62. HPV16 E7/PADRE 965.10
- [A synthetic agent derived from human papillomavirus (HPV) E7 nuclear protein which is used to produce vaccines against HPV infection and HPV-related neoplasms. HPV E7 oncogenic protein binds the retinoblastoma tumor suppressor protein, pRB, as well as a number of other cellular proteins, and serves as a transcriptional activator. This protein is important in the induction and maintenance of cellular transformation and is co-expressed in the majority of HPV-containing carcinomas. PADRE(R) is a proprietary family of molecules that enhances the immune systems response against an administered immunogen such as the HPV E7 nuclear protein. (NCI04) ( NCI )] (UMLS (NCI) C0338214) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
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