- 1. H SIMPLEX COMPLICAT NEC
- [ ] (UMLS (ICD9CM) C0153043) =Disease or Syndrome
| - 12. HSD17B7
- [This gene is involved in regulation of the biological potency of certain steroids. ( NCI )] (UMLS (NCI) C1333927) HSD17B7 Gene;
Hydroxysteroid (17-beta) Dehydrogenase 7 Gene =Gene or Genome ;
|
- 2. H SIMPLEX COMPLICAT NOS
- (UMLS (ICD9CM) C0153047) =Disease or Syndrome
| - 13. HsEg5 Protein
- (UMLS (NCI) C1173400) Human Eg5 Protein;
Human Kinesin Spindle Protein;
Kinesin Family Member 11;
Kinesin Heavy Chain;
Kinesin-Like 1 Protein;
KNSL1 Protein;
Thyroid Receptor Interacting Protein 5;
Xenopus Homolog of Eg5 =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 3. H SIMPLEX IRIDOCYCLITIS
- [ ] (UMLS (ICD9CM) C0153039) =Disease or Syndrome
| - 14. HSG (hysterosalpingogram)
- [Radiography of the uterus and fallopian tubes after the injection of a contrast medium. ( MSH )] (UMLS (CSP) C0020709) =Diagnostic Procedure
|
- 4. H SIMPLEX KERATITIS
- [ ] (UMLS (ICD9CM) C0153038) =Disease or Syndrome
| - 15. hsides
- (UMLS (HL7) C1552832) =Idea or Concept =TableFrame;
|
- 5. H SIMPLEX MENINGITIS
- (UMLS (ICD9CM) C0153045) =Disease or Syndrome
| - 16. hSMAD6
- [Encoded by MADH6 Gene (SMAD Family), ubiquitous (predominantly vascular endothelium) SMAD6 Protein Isoforms A (496-aa 53.5-kD) and B (235-aa) act similar to other MAD-proteins as second messengers distal to TGFBRs and contain an N-terminal DWA/MH1 domain and a C-terminal DWB/MH2 domain. An inhibitory SMAD phosphorylated by type 1 receptor kinase, SMAD6 acts as an antagonist of TGF-beta type 1 receptor signaling. A selective inhibitor of BMPs signaling; SMAD6 competes with SMAD4 for receptor-activated SMAD1. SMAD6 interacts with TGF-beta type I receptor superfamily members, SMAD1, HOXC8, and HOXC9. MADH6 and MADH7 form complexes. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0540682) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 6. H SIMPLEX OTITIS EXTERNA
- (UMLS (ICD9CM) C0153046) =Disease or Syndrome
| - 17. hSMAD7
- [Encoded by MADH7 Gene (SMAD Family) and induced by TGF-beta and IFNG, ubiquitous (lung, vascular endothelium highest) 426-amino acid SMAD7 Protein is an inhibitory Activin/TGFBR1 signaling component containing DWA/MH1 and DWB/MH2 domains. SMAD7 lacks C-terminal phosphorylation sites of other MAD proteins, suggesting distinct regulation. Adaptor SMAD7 constitutively recruits nuclear E3 ubiquitin ligase SMURF2 to TGFBR complexes preventing SMAD2 access and causing proteasomal and lysosomal receptor degradation. SMAD7-expressing cells are susceptible to apoptosis induced by TGFB, TNFA, serum withdrawal, or loss of cell adhesion. SMAD7 decreases NFKB activity, promoting apoptosis. RAS suppresses SMAD7 inhibition of NFKB and potentiation of apoptosis. MADH7 and MADH6 form complexes. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0664910) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 7. Hs
- [Supernumerary maxillary left primary canine ( HL7V3.0 )] (UMLS (HL7) C1552153) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
| - 18. hSNF2L
- [This protein is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. ( NCI )] (UMLS (NCI) C0165820) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 8. HS
- [the hour of sleep ( HL7V3.0 )] (UMLS (HL7) C1611093) =Temporal Concept ;
=TimingEvent;
| - 19. HSNIK
- [Encoded by MAP3K14 Gene (MAP3K Family) and expressed in small intestine, spleen, thymus, peripheral leukocytes, testis, prostate, ovary, and colon, autophosphorylated 947-amino acid 104-kD cytoplasmic Ser/Thr Protein Kinase NIK is involved in NFKB activation. NIK selectively activates NFKB cascades of TNF/NGF receptors and IL1R type-I. TNFA acts through TRAF2; IL1 acts through IRAK1 and TRAF6. LTBR and CD95 also act through NIK. NIK appears to bind TRAFs 2, 5, and 6, IKKA, and NFKB2/p100. Binding to TRAF2 involves the TRAF2 N- and C-terminal regions. NIK induces NFKB2/p100 processing, degradation of phosphoserine-induced ubiquitinated destruction of IKBA, and release of cytoplasmic NFKB for nuclear translocation and kappa-B DNA-mediated gene expression. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1335946) MAP3K14;
MAP3K14 Protein;
Mitogen-Activated Protein Kinase Kinase Kinase 14;
NFKB-Inducing Kinase;
NIK;
Serine/Threonine Protein Kinase NIK =Amino Acid, Peptide, or Protein; Enzyme |
- 9. hSARA
- [Encoded by MADHIP Gene, ubiquitous cytoplasmic SARA contains a FYVE domain zinc finger, seen in signaling molecules and required for SARA localization but not SMAD interaction. Able to bind PI-3 phosphate, SARA recruits SMAD2/3 to TGFBR. The SMAD binding domain (SBD) of SARA interacts with the SMAD2/3 MH2 domain; the C-terminal domain interacts with TGFBR. SMAD2/SMAD3 phosphorylation induces SARA dissociation, SMAD2/SMAD4 formation, and SMAD nuclear translocation. Alternate isoforms represent full-length (1425-aa, 156-kD) or truncated protein (1210-aa and 762-aa). Disruption of MADHIP appears to be involved in Alzheimer's disease. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0761585) MAD (Mothers Against Decapentaplegic, Drosophila) Homolog Interacting Protein, Receptor Activation Anchor;
MADH-Interacting Protein;
MADHIP;
Mothers Against Decapentaplegic Homolog Interacting Protein;
Novel Serine Protease;
NSP;
Receptor Activation Anchor Protein;
SARA Protein;
SMAD Anchor for Receptor Activation =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 20. HSORC1
- [Expressed by G1 cyclin-dependent kinase activated human ORC1L Gene (ORC1 Family), 861-aa 97-kDa nuclear Origin Recognition Complex Subunit 1 is the largest of 6 conserved subunits of the ORC complex that binds to the consensus ACS of Origins in an ATP-dependent manner, serves as a platform for assembly of additional initiation factors such as CDC6 and MCM proteins, initiates DNA replication, and is essential for viability. Bound to origins throughout the cell cycle, ORC and associated factors modulate local chromatin structure to facilitate replication initiation. Selectively phosphorylated during mitosis and unlike other ORC subunits, ORC1L levels vary during the cell cycle, regulated by ubiquitin-mediated proteolysis after replication initiation. Also involved in transcriptional silencing, ORC1L may interact with MYST histone acetyltransferase 2. (NCI) ( NCI )] (UMLS (NCI) C1335134) ORC1;
ORC1L;
Origin Recognition Complex 1;
Origin Recognition Complex Subunit 1;
Origin Recognition Complex Subunit 1 Homolog-Like;
Origin Recognition Complex Subunit 1-Like;
PARC1;
Replication Control Protein 1 =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 10. HSCR1
- [Human Oncogene RET is a mutated variant of RET Gene, which encodes Tyrosine-Protein Kinase Receptor RET, a type I membrane protein receptor for Glial Cell Line-Derived Neurotrophic Factor with an extracellular cadherin-like domain and important in neural crest development. Some oncogenic RET point mutations cause constitutive kinase activation. PTC1 oncogene involves fusion of RET kinase to the H4 dimerization leucine zipper. In PTC6, RET is fused to the N-terminal part of Transcriptional Intermediary Factor-1-alpha. In PTC7, RET is fused to a C-terminal part of TIF1-gamma. Oncogenic RET mutations are associated with Hirschsprung's disease, Multiple Endocrine Neoplasia, pheochromocytoma, hyperparathyroidism and medullary thyroid cancer. Oncogene RET disrupts normal cell function. ( NCI )] (UMLS (NCI) C0813143) MEN2A;
MEN2B;
MTC1;
Oncogene RET;
PTC Oncogene;
RET;
=Gene or Genome | - 21. hSWI/SNF
- [hSWI/SNF is an ATP-dependent chromatin-remodeling complex implicated in the regulation of gene expression, cell cycle control, and oncogenesis. The complex facilitates transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Subunits of the complex include: BAF57, BAF60a,-b,-c, BAF155, BAF170, BRG-1, BRM, and hSNF5/INI1. BAF57 contains an HMG domain adjacent to a kinesin-like region and binds DNA. BAF155 and BAF170 are BRG-1-associated proteins with dimerization motifs for transcription factors. BRM and BRG-1 are ATPase subunits of the complex and co-activators for nuclear hormone receptors. BRG-1 interacts with BRCA1, a nuclear phosphoprotein transcription and recombination accessory factor. ( NCI )] (UMLS (NCI) C1337050) Human SWI/SNF =Amino Acid, Peptide, or Protein; Enzyme
|
- 11. HSD17B2
- [This gene plays a role in hormonal signaling. ( NCI )] (UMLS (NCI) C1333926) HSD17B2 Gene;
Hydroxysteroid (17-beta) Dehydrogenase 2 Gene =Gene or Genome ;
| |
home
