- 1. H2A Histone Family, Member X
- [Encoded by human H2AX Gene (H2A Family) and expressed unlinked to replication in G1 and S-phase, 142-aa basal Histone H2AX has a unique conserved C-terminal sequence, QASQEY. NBS1/phospho-H2AX (gamma-H2AX) associate with irradiation-induced and V(D)J-induced DNA double-strand breaks. In pre-thymocytes, NBS1/gamma-H2AX form at RAG1-mediated TCRA V(D)J cleavage sites. NBS1/gamma-H2AX facilitate AID-dependent DNA break repair in G1 cells undergoing Ig heavy-chain constant region class switch recombination. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1172465) H2A.X;
H2A/X;
H2AFX;
H2AX;
H2AX Histone;
Histone H2A.X;
Histone H2AX;
=Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 2. H2A Histone Family, Member X Gene
- [This gene is involved in histone and nucleosome organization and chromatin compaction regulation. ( NCI )] (UMLS (NCI) C1415406) H2AFX;
H2AFX Gene =Gene or Genome |
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