- 1. (+)-Aldosterone
- [hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. ( CSP )] (UMLS (NCI) C0002006) =Steroid; Pharmacologic Substance; Hormone
| - 12. aldolase
- [An enzyme of the lyase class that catalyzes the cleavage of fructose 1,6-biphosphate to form dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. The enzyme also acts on (3S,4R)-ketose 1-phosphates. The yeast and bacterial enzymes are zinc proteins. (Enzyme Nomenclature, 1992) E.C. 4.1.2.13. ( MSH )] (UMLS (CSP) C0016762) =Amino Acid, Peptide, or Protein; Enzyme
|
- 2. Aldactone
- (UMLS (NCI) C0591054) =Steroid; Pharmacologic Substance
| - 13. Aldomet
- (UMLS (NCI) C0591055) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 3. Aldara
- (UMLS (NCI) C0718327) =Organic Chemical; Pharmacologic Substance ;
| - 14. aldosterone hypertension
- [ ] (UMLS (CSP) C0920393) =Pathologic Function ;
|
- 4. aldehyde
- [organic compounds containing a carbonyl group in the form -CHO. ( CSP )] (UMLS (CSP) C0001992) =Organic Chemical ;
| - 15. aldosterone inhibitor
- [agent that counteracts or opposes the action of aldosterone. ( CSP )] (UMLS (CSP) C0002007) =Pharmacologic Substance
|
- 5. aldehyde dehydrogenase
- [ ] (UMLS (CSP) C0684287) =Amino Acid, Peptide, or Protein; Enzyme ;
=aldehyde/ketone oxidoreductase;
| - 16. aldosterone receptor
- [Cytoplasmic proteins that specifically bind aldosterone and mediate its cellular effects. The aldosterone-bound receptor acts in the nucleus to regulate the transcription of specific segments of DNA. ( MSH )] (UMLS (CSP) C0051133) =Amino Acid, Peptide, or Protein; Receptor ;
|
- 6. Aldehyde Dehydrogenase 1 Family Member A2
- [Encoded by human ALDH1A2 Gene, Aldehyde Dehydrogenase 1A2 (ADH Family) is a 499-amino acid 54.8 kD putative cytoplasmic homotetrameric NAD-dependent retinaldehyde dehydrogenase, similar to class 1 aldehyde dehydrogenases that synthesizes retinoic acid from retinaldehyde. The protein contains conserved aldehyde dehydrogenase motifs: GXGXXXG motif NAD-binding domain, two peptide motifs, and cys301, critical for aldehyde group interaction. ALDH1A2 and CYP26A1 regulate local retinoic acid levels that act as a signal in developing and adult tissues; CYP26A1 metabolizes retinoic acid. In T-ALL, ectopically expressed TAL1 and LMO in T cells form a complex with GATA3 on the RALDH2-T promoter and activate transcription. (OMIM, Swiss-Prot, and NCI) ( NCI )] (UMLS (NCI) C0752609) Aldehyde Dehydrogenase 1 Family, Member A2;
Aldehyde Dehydrogenase 1A2;
ALDH1A2;
RALDH(II);
RALDH2;
RALDH-2;
Retinaldehyde-Specific Dehydrogenase Type 2 =Amino Acid, Peptide, or Protein; Enzyme | - 17. Aldosterone Receptor
- [Highly expressed as 4 alternative isoforms in kidney and sweat glands by human NR3C2 Gene (NR3 Family), ubiquitous phosphorylated Mineralocorticoid Receptor contains an N-terminal modulating domain, a DNA-binding domain, and a C-terminal steroid (mineralocorticoid/glucocorticoid)-binding domain. Absent ligand, NR3C2 resides in a heteromultimeric cytoplasmic complex with HSP90, HSP70, and FKBP4 or with HSD11B2 in the ER membrane. Ligand-activated NR3C2 translocates to the nucleus, binds to DNA mineralocorticoid response elements as a homodimer or heterodimer with NR3C1, and transactivates target gene expression, which increases ion and water transport; raises extracellular fluid volume and blood pressure; and lowers potassium levels. NR3C2 appears to bind NCOA1, NCOA2, TIF1, and NRIP1. NR3C2 defects cause PHA1 and early onset hypertension. (NCI) ( NCI )] (UMLS (NCI) C0066563) =Amino Acid, Peptide, or Protein; Receptor ;
|
- 7. Aldehyde Dehydrogenase 1 Family, Member A2 Gene
- [This gene plays a role in biosynthesis, cell differentiation and intercellular communication. ( NCI )] (UMLS (NCI) C1332076) ALDH1A2;
ALDH1A2 Gene;
=Gene or Genome | - 18. aldosterone stimulant
- [ ] (UMLS (CSP) C0599480) =Steroid; Pharmacologic Substance; Hormone
|
- 8. aldehyde lyase
- [Enzymes that catalyze a reverse aldol condensation. A molecule containing a hydroxyl group and a carbonyl group is cleaved at a C-C bond to produce two smaller molecules (ALDEHYDES or KETONES). EC 4.1.2. ( MSH )] (UMLS (CSP) C0001990) =Amino Acid, Peptide, or Protein; Enzyme
| - 19. aldosteronism
- [abnormality of electrolyte function caused by excessive secretion of aldosterone by the adrenal cortex. ( CSP )] (UMLS (CSP) C0020428) =Disease or Syndrome =adrenal disorder;
Adrenal Gland Hyperfunction =Bartter's Disease;
CONN'S SYNDROME;
Bartter's Disease;
|
- 9. aldehyde oxidase
- [An aldehyde oxidoreductase expressed predominantly in the LIVER; LUNGS; and KIDNEY. It catalyzes the oxidation of a variety of organic aldehydes and N-heterocyclic compounds to CARBOXYLIC ACIDS, and also oxidizes QUINOLINE and PYRIDINE derivatives. The enzyme utilizes molybdenum cofactor and FAD as cofactors. ( MSH )] (UMLS (CSP) C0051124) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 20. Aldrich syndrome
- [rare x-linked immunodeficiency syndrome of young boys characterized by eczema, thrombocytopenic purpura and recurrent pyogenic infection; IGM levels are low and IGA and IGE levels are elevated; lymphoreticular malignancies are common. ( CSP )] (UMLS (CSP) C0043194) =Disease or Syndrome ;
=HEMORRHAGIC COND NOS;
Genetic Condition;
hypoimmunity;
Congenital anomalies of the integument;
syndrome;
thrombocytopenia;
inborn immunodeficiency;
Purpura, Thrombocytopenic |
- 10. aldehyde reductase
- [aldose reductase converts glucose to sorbitol, mediating sorbitol toxicity (neuropathy and retinopathy) in diabetes mellitus do not confuse with EC 1.1.1.1, ALCOHOL DEHYDROGENASE. ( CSP )] (UMLS (CSP) C0002003) =Amino Acid, Peptide, or Protein; Enzyme
| - 21. aldrin
- [A highly poisonous substance that was formerly used as an insecticide. The manufacture and use has been discontinued in the U.S. (From Merck Index, 11th ed) ( MSH )] (UMLS (CSP) C0002011) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 11. aldehyde/ketone oxidoreductase
- [ ] (UMLS (CSP) C0596065) =Amino Acid, Peptide, or Protein; Enzyme =dehydrogenase;
=glyceraldehyde 3 phosphate dehydrogenase;
alpha ketoglutarate dehydrogenase;
pyruvate dehydrogenase;
pyruvate oxidase;
aldehyde dehydrogenase;
| |
home
