[secretion of histamine from mast cell and basophil granules by exocytosis; this can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's Fc receptors; once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects. ( CSP )]
UMLS (CSP) C0019595 Relation/PAR: Allergy
host response