- 1. 1H-Imidazo(4,5-c)quinolin-4-amine, 1-(2-methylpropyl)-
- [A substance that improves the body's natural response to infection and disease. It is being studied as a topical agent (something used on the surface of the body) for the prevention of some types of cancer. It belongs to the family of drugs called biological response modifiers. ( NCI )] (UMLS (NCI) C0165032) =Organic Chemical; Pharmacologic Substance =S 26308;
[IM900] IMMUNOLOGICAL AGENTS, OTHER =IMIQUIMOD 5 % | - 7. 1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-
- [cytotoxic alkylating agent used as an antineoplastic primarily for treatment of malignant melanoma and in combination chemotherapy for Hodgkin's disease and sarcomas; administered intravenously; abbreviated DTIC. ( CSP )] (UMLS (NCI) C0010927) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
imidazole;
Triazene Compound;
imidazole carboxamide =3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide;
DACARBAZINE 100 MG;
DACARBAZINE 200 MG;
|
- 2. 1H-Imidazole, 1-(2-((7-chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, Mononitrate
- [The nitrate salt form of sertaconazole, a synthetic imidazole derivative with antifungal property. Sertaconazole nitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and the inhibition of ergosterol synthesis, an essential component of the cell membrane of fungi. This leads to a disruption of cell membrane permeability and leakage of adenine triphosphate (ATP) and other constituents from fugal cells. ( NCI )] (UMLS (NCI) C0771896) Sertaconazole Nitrate;
=Organic Chemical; Pharmacologic Substance | - 8. 1H-Imidazole-5-Carboxylic Acid, 1-((1R)-1-phenylethyl)-, Ethyl Ester
- [An imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid (GABA) like effects, mediated through GABA-A receptor. The action enhances the inhibitory effect of GABA on the central nervous system by causing chloride channel opening events which leads to membrane hyperpolarization. ( NCI )] (UMLS (NCI) C0015131) =Organic Chemical; Pharmacologic Substance ;
=imidazole;
[CN203] GENERAL ANESTHETICS, OTHER =ETOMIDATE 2 MG/ML |
- 3. 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, Monohydrochloride
- [The hydrochloride salt form of tetrahydrozoline, an imidazole derivative with sympathomimetic property. Applied locally to the eye or nose, tetrahydrozoline binds to and activates alpha-adrenergic receptors, resulting in vasoconstriction and decreased nasal and ophthalmic congestion. ( NCI )] (UMLS (NCI) C0148485) =Organic Chemical; Pharmacologic Substance ;
=TETRAHYDROZOLINE;
=tetrahydrozoline 0.5 MG/ML Nasal Solution;
TETRAHYDROZOLINE HYDROCHLORIDE 0.1 %;
| - 9. 1H-Imidazole-5-carboxylic Acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester
- [A synthetic imidazole derivative prodrug with an antihypertensive property. Upon hydrolysis, olmesartan medoxomil is converted to olmesartan. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor of angiotensin II in vascular smooth muscle and adrenal gland, thereby competing angiotensin II binding to the receptor. This prevents angiotensin II-induced vasoconstriction and decreases aldosterone production, thereby preventing aldosterone-stimulated sodium retention and potassium excretion. ( NCI )] (UMLS (NCI) C0386393) =Organic Chemical; Pharmacologic Substance ;
=Olmesartan;
Unclassified Ingredients =OLMESARTAN MEDOXOMIL 20 MG;
OLMESARTAN MEDOXOMIL 40 MG;
OLMESARTAN MEDOXOMIL 5 MG |
- 4. 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, Monohydrochloride
- [The hydrochloride salt form of naphazoline, an imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive properties. Upon ocular administration, naphazoline hydrochloride exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness. ( NCI )] (UMLS (NCI) C0282259) =Organic Chemical; Pharmacologic Substance ;
=NAPHAZOLINE;
=NAPHAZOLINE HYDROCHLORIDE 0.025 %;
NAPHAZOLINE HYDROCHLORIDE 0.05 %;
NAPHAZOLINE HYDROCHLORIDE 0.02 %;
NAPHAZOLINE HYDROCHLORIDE 0.1 %;
NAPHAZOLINE HYDROCHLORIDE 0.012 % | - 10. 1H-imidazo[4,5-f]quinoline, acetamide deriv
- [A synthetic imidazoquinoline with antineoplastic activity. Acodazole intercalates into DNA, resulting in disruption of DNA replication. Use of this agent has been associated with significant cardiotoxicity. (NCI04) ( NCI )] (UMLS (NCI) C0050565) =Organic Chemical; Pharmacologic Substance ;
|
- 5. 1H-Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-
- [A drug that increases the effectiveness of radiation therapy. ( NCI )] (UMLS (NCI) C0059682) =Organic Chemical; Pharmacologic Substance ;
| - 11. 2-(1-H-imidazol-4-yl) Ethylamine Dihydrochloride
- [A drug being studied for its ability to enhance the effectiveness of IL-2 in treating acute myeloid leukemia. ( NCI )] (UMLS (NCI) C0543456) =Organic Chemical; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine
|
- 6. 1H-Imidazole-2-methanamine, 4,5-Dihydro-N-phenyl-N-(phenylmethyl)-, Phosphate(1:1)
- [The phosphate salt of antazoline, an ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents the typical allergic symptoms caused by histamine activities on capillaries, skin, mucous membranes, gastrointestinal and bronchial smooth muscles. These histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Antazoline is used to provide symptomatic relieve of allergic symptoms. ( NCI )] (UMLS (NCI) C0003144) =Organic Chemical; Pharmacologic Substance
| - 12. 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic Acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-, Ethyl Ester
- [An imidazo-benzodiazepine derivative, effective in reversing benzodiazepine-induced activities. Flumazenil antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel opening events and inhibiting neuronal hyperpolarization. As a result, flumazenil reverses benzodiazepine-induced effects including sedation, psychomotor deficits, amnesia, and hypoventilation in a dose-dependent manner. ( NCI )] (UMLS (NCI) C0016293) =Organic Chemical; Pharmacologic Substance ;
=Benzodiazepinones;
[AD900] ANTIDOTES/DETERRENTS, OTHER =FLUMAZENIL 0.1 MG/ML |
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