hCIT529I10

[Nuclear Receptor Co-Repressor 1, encoded by the NCOR1, mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. This protein is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. (from LocusLink) ( NCI )]

UMLS (NCI) C1384567

hN-CoR
KIAA1047
N-CoR
NCOR1
N-CoR1
Nuclear Receptor Corepressor
Nuclear Receptor Co-Repressor 1
Thyroid Hormone- and Retinoic Acid Receptor-Associated Corepressor 1
TRAC1

Amino Acid, Peptide, or Protein
Biologically Active Substance

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