[The anhydrous form of docetaxel, a semisynthetic side-chain analogue of paclitaxel with antineoplastic property. Docetaxel binds specifically to the beta-tubulin subunit of microtubules and thereby antagonizes the disassembly of the microtubule proteins. This results in the persistence of aberrant microtubule structures and results in cell-cycle arrest and subsequent cell death. ( NCI )]
UMLS (NCI) C0771375DOCETAXEL, ANHYDROUS
- Organic Chemical
- Pharmacologic Substance